6 results on '"Yuka EGUCHI"'
Search Results
2. Accessory breast cancer in the inframammary region: a case report and review of the literature
- Author
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Heiji Yoshinaka, Yuki Nomoto, Takao Ohtsuka, Keiichiro Uchikura, Yoshiaki Shinden, Kazunobu Sueyoshi, Ayako Nagata, Hazuki Saho, Naoki Hayashi, and Yuka Eguchi
- Subjects
Sentinel node biopsy ,Surgical margin ,medicine.medical_specialty ,RD1-811 ,medicine.diagnostic_test ,business.industry ,Case Report ,Inframammary region ,Ductal carcinoma ,Sentinel node ,medicine.disease ,Accessory breast ,Accessory breast cancer ,Axilla ,medicine.anatomical_structure ,Breast cancer ,Biopsy ,medicine ,Carcinoma ,Surgery ,Radiology ,business - Abstract
Background Although a few cases of accessory breast cancer (ABC) have been reported, most were in the axillary region. We encountered an extremely rare case of ABC in the inframammary region (IMR). Case presentation The patient was a 68-year-old postmenopausal woman who had noticed a congenital accessory nipple in her left IMR with slight, occasional discharge 20 years ago. Recently, she noticed a mass under the accessory nipple and visited a nearby clinic; fine-needle aspiration cytology of the mass revealed that it was malignant. She presented to our department 2 weeks after she had noticed the mass. Physical and imaging examinations showed an irregular tumor mass 1.7 × 1.4 × 1.0 cm in size connected to the accessory nipple beneath the left normal breast. Neither distant metastasis nor lymph node swelling was observed. Ultrasound-guided core needle biopsy revealed the mass to be invasive ductal carcinoma. We diagnosed her tumor as ABC in the left IMR; cT1cN0M0: stage IA. Curative wide resection with sentinel node biopsy was performed. Intraoperative evaluation of the frozen section revealed a hot and green ipsilateral axillary lymph node that was free from carcinoma; therefore, nodal dissection was avoided. Histopathological examination including immunochemical staining revealed that the tumor was invasive ductal carcinoma arising from the accessory breast tissue, scirrhous type, 1.7 × 1.4 × 1.0 cm in size, with a solid intraductal component. There was no lymphovascular infiltration, and the surgical margin was 1.5 cm or more. The tumor was estrogen and progesterone receptor-positive, Her2/neu-negative, and had a Ki-67 labeling index of 20%. There was no involvement of the three hot and/or green nodes. The final classification was pT1cN0(sn)M0: stage IA. Letrozole 2.5 mg/day will be administered for 5 years as adjuvant hormonal therapy. Conclusions A cutaneous and/or subcutaneous lesion except for proper breast tissue on the milk line, or mammary ridge from axilla to groin may be an accessory breast tissue. Its serial abnormalities must be worried malignant potential to ductal carcinoma which needs some imaging and pathological examinations for definitive diagnosis and appropriate treatment according to the usual orthotopic breast cancer without delay. more...
- Published
- 2021
Catalog
3. Two cases of radiation-associated angiosarcoma of the breast
- Author
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Yuko Kijima, Yoshiaki Shinden, Heiji Yoshinaka, Yuki Nomoto, Akihide Tanimoto, Tsubasa Hiraki, Shoji Natsugoe, Ikumi Kitazono, Yuka Eguchi, and Munetugu Hirata
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medicine.medical_specialty ,Open biopsy ,medicine.medical_treatment ,lcsh:Surgery ,Case Report ,030218 nuclear medicine & medical imaging ,Secondary angiosarcoma ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Biopsy ,medicine ,Angiosarcoma ,medicine.diagnostic_test ,business.industry ,lcsh:RD1-811 ,medicine.disease ,Radiation therapy ,030220 oncology & carcinogenesis ,Skin biopsy ,Skin grafting ,Radiology ,business ,Mastectomy ,Breast-conserving treatment - Abstract
Background The incidence of radiation-associated angiosarcoma (RAA) of the breast has been increasing, and its prognosis is reportedly poor. It is important to remove tumor tissues completely to prevent recurrence. Case presentation We report two cases of patients with RAA of the breast. Both patients had a nodule in their remaining breast a few years after undergoing breast-conserving surgery and radiation therapy for breast cancer. The nodules were diagnosed as angiosarcoma by skin biopsy and open biopsy, respectively. To determine the extent of lesion spread, mapping biopsy was performed before surgery. Both patients underwent mastectomy, extensive skin resection, and split skin grafting. Pathological findings showed that their tumors could be completely resected. After surgery, chemotherapy was performed. Conclusion In our cases, no local or distant recurrence has been detected in either patient for over 4 years. We identified the range of tumor invasion by preoperative mapping biopsy and completely resected all tumor tissue. more...
- Published
- 2018
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4. A Case of Invasive Micropapillary Carcinoma of the Breast in an 82-year-old Man
- Author
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Takako Yoshioka, Yuka Eguchi, Shoji Natsugoe, Yuko Kijima, Heiji Yoshinaka, and Munetsugu Hirata
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Oncology ,03 medical and health sciences ,medicine.medical_specialty ,0302 clinical medicine ,business.industry ,030220 oncology & carcinogenesis ,Internal medicine ,General surgery ,medicine ,030211 gastroenterology & hepatology ,Micropapillary carcinoma ,business - Published
- 2016
- Full Text
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5. Apocrine papillary lesion: comparison of pathological findings from 22 years previously and the present
- Author
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Ayako Nagata, Yasuyo Ohi, Naoki Hayashi, Shoji Natsugoe, Yuko Kijima, Yuka Eguchi, Heiji Yoshinaka, Yoshiaki Shinden, Yuki Nomoto, and Kazunobu Sueyoshi
- Subjects
0301 basic medicine ,Pathology ,medicine.medical_specialty ,Breast Neoplasms ,Malignancy ,Metastasis ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Biopsy ,medicine ,Humans ,Pharmacology (medical) ,Radiology, Nuclear Medicine and imaging ,Aged ,medicine.diagnostic_test ,Papilloma ,business.industry ,Sentinel Lymph Node Biopsy ,Carcinoma, Ductal, Breast ,Apocrine ,General Medicine ,Ductal carcinoma ,medicine.disease ,Carcinoma, Papillary ,030104 developmental biology ,Oncology ,030220 oncology & carcinogenesis ,Female ,Biopsy, Large-Core Needle ,medicine.symptom ,business - Abstract
Apocrine papillary lesion (APL) is difficult to diagnose as benign or malignant. We experienced an APL remaining in the body for 22 years. We present a case of a 71-year-old woman who had undergone excisional biopsy 22 years previously at the first hospital that she visited. 1 year previously, she had undergone fine-needle aspiration cytology at a second hospital, and the lesion was diagnosed as potentially malignant. She underwent core-needle biopsy at a third hospital, but whether the lesion was benign or malignant could not be definitively diagnosed. We performed right mastectomy and sentinel lymph-node biopsy, because her tumor was suspected to be malignant based on imaging means, and malignancy could not be ruled out on either biopsy or cytology. The histopathological diagnosis was tiny foci of apocrine proliferative lesion with massive hemorrhagic necrosis and no tumor metastasis in two sentinel lymph nodes. Retrospectively, we compared all of the patient’s previous specimens with the present ones, and applied the recent pathological diagnostic criteria. Although the biopsy specimen excised 22 years ago suggested an encapsulated apocrine papillary carcinoma or a papilloma with apocrine ductal carcinoma in situ, neither infiltration nor metastasis has occurred. Furthermore, neither the pathological findings nor the clinical behavior has changed over time. more...
- Published
- 2018
6. Impaired wound healing and expansion of a large ulcer after bevacizumab with paclitaxel for skin metastases from breast cancer: report of a case
- Author
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Heiji Yoshinaka, Akihiro Nakajo, Tetsuya Ijichi, Hideo Arima, Hiroshi Okumura, Yuka Eguchi, Munetsugu Hirata, Yuko Kijima, Hiroshi Kurahara, Yoshikazu Uenosono, Yoshiaki Shinden, Shoji Natsugoe, and Sumiya Ishigami more...
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medicine.medical_specialty ,Skin Neoplasms ,Axillary lymph nodes ,Bevacizumab ,Paclitaxel ,medicine.medical_treatment ,Breast Neoplasms ,Antibodies, Monoclonal, Humanized ,chemistry.chemical_compound ,Breast cancer ,Fatal Outcome ,Antineoplastic Combined Chemotherapy Protocols ,Surgical Wound Dehiscence ,medicine ,Humans ,Total Mastectomy ,Thoracic Wall ,Chemotherapy ,business.industry ,Granulation tissue ,General Medicine ,Middle Aged ,medicine.disease ,Combined Modality Therapy ,Surgery ,medicine.anatomical_structure ,chemistry ,Female ,Neoplasm Recurrence, Local ,business ,Thoracic wall ,Eribulin ,medicine.drug - Abstract
A 48-year-old Japanese woman was found to have local recurrence of breast cancer in the chest wall following neoadjuvant chemotherapy, total mastectomy with axillary lymphadenectomy, postoperative radiation therapy to the chest wall, and adjuvant systemic therapy using trastuzumab. As a third line of treatment after recurrence, bevacizumab with paclitaxel was initiated for several metastatic lesions on the skin of the chest wall, left internal costal lymph nodes, and right axillary lymph nodes. The wound on the chest wall continued to expand in diameter and depth after the third course of bevacizumab with paclitaxel until the rib was exposed. After stopping the bevacizumab, granulation tissue expanded and by 3 months, had covered the bottom of the ulcer. The patient died soon thereafter, despite systemic chemotherapy with eribulin; however, there was no further bleeding from the ulcer on the chest wall or the exposed ribs. more...
- Published
- 2013
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