1. Pregnancy outcomes and influencing factors of fresh embryo transfer cycle for primary and secondary infertility
- Author
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Xiong Yao, Ye Zhaoyang
- Subjects
infertility ,embryo transfer ,fresh cycle ,assisted reproductive technology ,pregnancy outcome ,influencing factor ,Medicine - Abstract
Objective To analyze the pregnancy outcomes and influencing factors of fresh embryo transfer cycle in patients with primary and secondary infertility. Methods Clinical data of infertility patients who underwent fresh embryo transfer cycle were collected. All patients were divided into the primary and secondary infertility groups according to the type of infertility. Clinical data,infertility factors and pregnancy outcomes were statistically compared between two groups. The influencing factors of different pregnancy outcomes were identified by logistic regression analysis. Results The clinical pregnancy and live birth rates in the primary infertility group were higher than those in the secondary infertility group (both P < 0.05). There was no statistical difference in the incidence of spontaneous abortion. Maternal age,duration of infertility,number of oocytes retrieved,number of high-quality embryos and endometrial thickness were correlated with clinical pregnancy (all P < 0.05). For clinical pregnancy outcomes,without adjusting for any clinical characteristics,the odds ratio (OR) for clinical pregnancy between primary and secondary infertility was 1.34 (1.14-1.59, P < 0.001). After adjusting for male and female factors as well as embryo factors,the OR for clinical pregnancy between primary and secondary infertility was 1.25 (1.02-1.53, P = 0.032). For live birth outcomes,without adjusting for any factors,the OR for live birth between primary and secondary infertility was 1.48 (1.08-2.13, P = 0.014). After adjusting for male and female factors as well as embryo factors,the OR for live birth between primary and secondary infertility was 1.27 (0.86-1.88, P = 0.237). Conclusion In the fresh embryo transfer cycle,higher clinical pregnancy and live birth rates can be obtained in primary infertility patients compared with their counterparts with secondary infertility.
- Published
- 2023
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