5 results on '"West Jordan"'
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2. Energy metabolism during damaging contractile activity in isolated skeletal muscle: A31P-NMR study
- Author
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J. A. West-Jordan, Peter A. Martin, Malcolm J. Jackson, Raymond J. Abraham, and Rht Edwards
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medicine.medical_specialty ,Magnetic Resonance Spectroscopy ,Phosphocreatine ,Clinical Biochemistry ,Stimulation ,Biology ,Biochemistry ,Phosphates ,chemistry.chemical_compound ,Adenosine Triphosphate ,Internal medicine ,medicine ,Animals ,Myocyte ,Lactic Acid ,Creatine Kinase ,Muscles ,Biochemistry (medical) ,Skeletal muscle ,Rats, Inbred Strains ,General Medicine ,Metabolism ,Hydrogen-Ion Concentration ,Electric Stimulation ,Rats ,Cytosol ,Endocrinology ,medicine.anatomical_structure ,chemistry ,Lactates ,biology.protein ,Female ,Creatine kinase ,medicine.symptom ,Energy Metabolism ,Glycogen ,Muscle Contraction ,Muscle contraction - Abstract
Creatine kinase (CK) release in response to excessive electrically stimulated contractile activity has been studied in isolated rat soleus muscles. The exacerbation of CK release induced by contractile activity was found to be directly related to the length of time for which the muscle was stimulated and indirectly related to the recovery of force following the end of stimulation. 31P-NMR studies were undertaken using a recirculating superfused muscle preparation and demonstrated that muscles subjected to two different stimulation protocols (stimulation for 0.5 s every 2 s in oxygenated medium or for 1.5 s every 2 s in anoxic medium) had similar falls in ATP content and pH despite a Substantially greater release of CK from the muscles stimulated under anoxia. However, stimulated muscles under anoxia showed a more rapid fall and reduced recovery of phosphocreatine and a greater sustained elevation of inorganic phosphate than muscles in oxygenated medium. It is concluded that only part of the increased loss of CK from muscles stimulated in anoxic medium can be explained by release from cells which have lost energy supplies and therefore that other mechanisms must exist which allow release of CK and other cytosolic enzymes from muscle cells.
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- 1991
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3. Energy dependence of cytosolic enzyme efflux from rat skeletal muscle
- Author
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Peter A. Martin, Richard H.T. Edwards, Raymond J. Abraham, Julie A. West-Jordan, and Malcolm J. Jackson
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Magnetic Resonance Spectroscopy ,Phosphocreatine ,Clinical Biochemistry ,chemistry.chemical_element ,Calcium ,Biochemistry ,2,4-Dinitrophenol ,chemistry.chemical_compound ,Adenosine Triphosphate ,Cytosol ,medicine ,Animals ,Creatine Kinase ,Calcimycin ,biology ,Muscles ,Biochemistry (medical) ,Skeletal muscle ,Rats, Inbred Strains ,General Medicine ,Rats ,medicine.anatomical_structure ,chemistry ,biology.protein ,Biophysics ,Creatine kinase ,Female ,Energy Metabolism ,Adenosine triphosphate ,Intracellular ,Dinitrophenols ,Deoxycholic Acid - Abstract
(1) A recirculating isolated superfused skeletal muscle preparation has been developed for the study of rat soleus muscles at physiological temperature using 31P Nuclear Magnetic Resonance (NMR). (2) This system has been used to study intracellular muscle high energy phosphate content and pH during experimental damage to the muscle induced by 2,4-dinitrophenol, deoxycholate and the calcium ionophore, A23187. (3) Results indicate that release of intracellular cytosolic enzymes from damaged skeletal muscle may be induced by phosphocreatine (PCr) and adenosine trisphosphate (ATP) depletion, but under certain circumstances intracellular enzymes can be released from skeletal muscle without any fall in muscle PCr or ATP content.
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- 1990
4. 31P NMR studies on recovery from hypoxia of human tumor cells
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A. Smith, Raymond J. Abraham, J. A. West-Jordan, H. M. Warenius, J. A. Gardner, Richard H.T. Edwards, and S. Myint
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Magnetic Resonance Spectroscopy ,fungi ,Tumor cells ,Metabolism ,Adenocarcinoma ,Biology ,Hypoxia (medical) ,In vitro ,Cell Line ,Phosphates ,Human tumor ,Biochemistry ,Cell culture ,Neoplasms ,Colonic Neoplasms ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,31p nmr spectroscopy ,medicine.symptom ,Hypoxia ,Incubation - Abstract
We describe the use of 31P NMR spectroscopy in the study of metabolic changes related to hypoxia in cultured human tumor cells in vitro. The 31P NMR spectrum can easily distinguish between metabolically active cells, metabolically inactive “dormant” cells, and necrotic cells. A crucial observation was that of the ability of the “dormant” cells to resume active metabolism on incubation with oxygen after long periods of hypoxia. © 1987 Academic Press. Inc.
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- 1987
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5. Exceptional fossil assemblages confirm the existence of complex Early Triassic ecosystems during the early Spathian
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Arnaud Brayard, Kevin G. Bylund, L. J. Krumenacker, Daniel A. Stephen, Michael Hautmann, Emmanuel Fara, Christopher P. Smith, Thomas Laville, James F. Jenks, Gilles Escarguel, Nicolas Goudemand, Nicolas Olivier, Sylvain Charbonnier, Emmanuelle Vennin, Biogéosciences [UMR 6282] [Dijon] (BGS), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), Muséum national d'Histoire naturelle (MNHN), Équipe 6 - Paléontologie, Paléoécologie, Paléobiogéographie, Évolution (P3E), Laboratoire d'Ecologie des Hydrosystèmes Naturels et Anthropisés (LEHNA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Magmas et Volcans (LMV), Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement et la société-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Observatoire de Physique du Globe de Clermont-Ferrand (OPGC), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Institut de Génomique Fonctionnelle de Lyon (IGFL), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Spanish Fork, West Jordan, Department of Earth Sciences, Utah Valley University, Utah Valley University (UVU), Paläontologisches Institut und Museum der Universität Zürich, Karl-Schmid Strasse 4, CH-8006 Zürich, Switzerland (PALäONTOLOGISCHES INSTITUT UND MUSEUM DER UNIVERSITäT ZüRICH, KARL-SCHMID STRASSE 4, CH-8006 ZüRICH, SWITZERLAND), Universität Zürich [Zürich] = University of Zurich (UZH), Department of Geosciences, Idaho State University, University of Zurich, Centre de Recherche en Paléontologie - Paris (CR2P), Muséum national d'Histoire naturelle (MNHN)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), 140 South 700 East, Spanish Fork, 1134 Johnson Ridge Lane, West Jordan, Universität Zürich [Zürich] (UZH), Department of Geosciences, Idaho State University, Biogéosciences [UMR 6282] (BGS), Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), and Paläontologisches Institut und Museum der Universität Zürich
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010506 paleontology ,Permian ,Paleozoic ,Fauna ,Science ,Early Triassic ,Evolutionary fauna ,10125 Paleontological Institute and Museum ,010502 geochemistry & geophysics ,01 natural sciences ,Article ,Paleontology ,14. Life underwater ,[SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces, environment ,0105 earth and related environmental sciences ,Extinction event ,Multidisciplinary ,Palaeontology ,Palaeoecology ,Biota ,15. Life on land ,Geography ,560 Fossils & prehistoric life ,[SDU.STU.ST]Sciences of the Universe [physics]/Earth Sciences/Stratigraphy ,[SDE]Environmental Sciences ,Paleoecology ,Medicine ,[SDE.BE]Environmental Sciences/Biodiversity and Ecology ,[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/Paleontology - Abstract
The mass extinction characterizing the Permian/Triassic boundary (PTB; ~ 252 Ma) corresponds to a major faunal shift between the Palaeozoic and the Modern evolutionary fauna. The temporal, spatial, environmental, and ecological dynamics of the associated biotic recovery remain highly debated, partly due to the scarce, or poorly-known, Early Triassic fossil record. Recently, an exceptionally complex ecosystem dated from immediately after the Smithian/Spathian boundary (~ 3 myr after the PTB) was reported: the Paris Biota (Idaho, USA). However, the spatiotemporal representativeness of this unique assemblage remained questionable as it was hitherto only reported from a single site. Here we describe three new exceptionally diverse assemblages of the same age as the Paris Biota, and a fourth younger one. They are located in Idaho and Nevada, and are taxonomic subsets of the Paris Biota. We show that the latter covered a region-wide area and persisted at least partially throughout the Spathian. The presence of a well-established marine fauna such as the Paris Biota, as soon as the early Spathian, indicates that the post-PTB biotic recovery and the installation of complex ecosystems probably took place earlier than often assumed, at least at a regional scale.
- Published
- 2021
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