25 results on '"Quinn, D"'
Search Results
2. Reference genes for gene expression studies in the mouse heart
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Adrián Ruiz-Villalba, Andrea Mattiotti, Quinn D. Gunst, Sara Cano-Ballesteros, Maurice J. B. van den Hoff, and Jan M. Ruijter
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Medicine ,Science - Abstract
Abstract To be accurate, quantitative Polymerase Chain Reaction (qPCR) studies require a set of stable reference genes for normalization. This is especially critical in cardiac research because of the diversity of the clinical and experimental conditions in the field. We analyzed the stability of previously described as potential reference genes in different subsets of cardiac tissues, each representing a different field in cardiac research. The qPCR dataset was based on 119 different tissue samples derived from cardiac development to pathology in mouse adult hearts. These samples were grouped into 47 tissue types. The stability of 9 candidate genes was analyzed in each of 12 experimental conditions comprising different groupings of these tissue types. Expression stability was determined with the geNorm module of qbase+. This analysis showed that different sets of two or three reference genes are required for analysis of qPCR data in different experimental conditions in murine cardiac research.
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- 2017
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3. Reducing soft-tissue shrinkage artefacts caused by staining with Lugol’s solution
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B. De Bakker, N. H. J. Lobe, Quinn D. Gunst, Jaco Hagoort, Y. Dawood, B. A. Siadari, M. J. B. Van Den Hoff, Gustav J. Strijkers, Jan M. Ruijter, Graduate School, Medical Biology, ACS - Heart failure & arrhythmias, APH - Personalized Medicine, APH - Quality of Care, ARD - Amsterdam Reproduction and Development, Biomedical Engineering and Physics, ACS - Atherosclerosis & ischemic syndromes, AMS - Musculoskeletal Health, and AMS - Sports
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Lugol's Solution ,Pathology ,medicine.medical_specialty ,Science ,Contrast Media ,Computed tomography ,Article ,Mice ,Fetus ,Medical research ,Developmental biology ,medicine ,Animals ,Humans ,Shrinkage ,Multidisciplinary ,Staining and Labeling ,medicine.diagnostic_test ,Osmotic concentration ,Chemistry ,Soft tissue ,Tissue shrinkage ,Hydrogen-Ion Concentration ,Iodides ,Staining ,Connective Tissue ,Medicine ,Anatomy ,Artifacts ,Tomography, X-Ray Computed ,Tissue volume - Abstract
Diffusible iodine-based contrast-enhanced computed tomography (diceCT) is progressively used in clinical and morphological research to study developmental anatomy. Lugol’s solution (Lugol) has gained interest as an effective contrast agent; however, usage is limited due to extensive soft-tissue shrinkage. The mechanism of Lugol-induced shrinkage and how to prevent it is largely unknown, hampering applications of Lugol in clinical or forensic cases where tissue shrinkage can lead to erroneous diagnostic conclusions. Shrinkage was suggested to be due to an osmotic imbalance between tissue and solution. Pilot experiments pointed to acidification of Lugol, but the relation of acidification and tissue shrinkage was not evaluated. In this study, we analyzed the relation between tissue shrinkage, osmolarity and acidification of the solution during staining. Changes in tissue volume were measured on 2D-segmented magnetic resonance and diceCT images using AMIRA software. Partial correlation and stepwise regression analysis showed that acidification of Lugol is the main cause of tissue shrinkage. To prevent acidification, we developed a buffered Lugol’s solution (B-Lugol) and showed that stabilizing its pH almost completely prevented shrinkage without affecting staining. Changing from Lugol to B-Lugol is a major improvement for clinical and morphological research and only requires a minor adaptation of the staining protocol.
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- 2021
4. Identifying the evolutionary building blocks of the cardiac conduction system.
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Bjarke Jensen, Bastiaan J D Boukens, Alex V Postma, Quinn D Gunst, Maurice J B van den Hoff, Antoon F M Moorman, Tobias Wang, and Vincent M Christoffels
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Medicine ,Science - Abstract
The endothermic state of mammals and birds requires high heart rates to accommodate the high rates of oxygen consumption. These high heart rates are driven by very similar conduction systems consisting of an atrioventricular node that slows the electrical impulse and a His-Purkinje system that efficiently activates the ventricular chambers. While ectothermic vertebrates have similar contraction patterns, they do not possess anatomical evidence for a conduction system. This lack amongst extant ectotherms is surprising because mammals and birds evolved independently from reptile-like ancestors. Using conserved genetic markers, we found that the conduction system design of lizard (Anolis carolinensis and A. sagrei), frog (Xenopus laevis) and zebrafish (Danio rerio) adults is strikingly similar to that of embryos of mammals (mouse Mus musculus, and man) and chicken (Gallus gallus). Thus, in ectothermic adults, the slow conducting atrioventricular canal muscle is present, no fibrous insulating plane is formed, and the spongy ventricle serves the dual purpose of conduction and contraction. Optical mapping showed base-to-apex activation of the ventricles of the ectothermic animals, similar to the activation pattern of mammalian and avian embryonic ventricles and to the His-Purkinje systems of the formed hearts. Mammalian and avian ventricles uniquely develop thick compact walls and septum and, hence, form a discrete ventricular conduction system from the embryonic spongy ventricle. Our study uncovers the evolutionary building plan of heart and indicates that the building blocks of the conduction system of adult ectothermic vertebrates and embryos of endotherms are similar.
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- 2012
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5. Cardiac regeneration from activated epicardium.
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Bram van Wijk, Quinn D Gunst, Antoon F M Moorman, and Maurice J B van den Hoff
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Medicine ,Science - Abstract
In contrast to lower vertebrates, the mammalian heart has a very limited regenerative capacity. Cardiomyocytes, lost after ischemia, are replaced by fibroblasts. Although the human heart is able to form new cardiomyocytes throughout its lifespan, the efficiency of this phenomenon is not enough to substitute sufficient myocardial mass after an infarction. In contrast, zebrafish hearts regenerate through epicardial activation and initiation of myocardial proliferation. With this study we obtain insights into the activation and cellular contribution of the mammalian epicardium in response to ischemia. In a mouse myocardial infarction model we analyzed the spatio-temporal changes in expression of embryonic epicardial, EMT, and stem cell markers and the contribution of cells of the Wt1-lineage to the infarcted area. Though the integrity of the epicardial layer overlaying the infarct is lost immediately after the induction of the ischemia, it was found to be regenerated at three days post infarction. In this regenerated epicardium, the embryonic gene program is transiently re-expressed as well as proliferation. Concomitant with this activation, Wt1-lineage positive subepicardial mesenchyme is formed until two weeks post-infarction. These mesenchymal cells replace the cardiomyocytes lost due to the ischemia and contribute to the fibroblast population, myofibroblasts and coronary endothelium in the infarct, and later also to the cardiomyocyte population. We show that in mice, as in lower vertebrates, an endogenous, epicardium-dependent regenerative response to injury is induced. Although this regenerative response leads to the formation of new cardiomyocytes, their number is insufficient in mice but sufficient in lower vertebrates to replace lost cardiomyocytes. These molecular and cellular analyses provide basic knowledge essential for investigations on the regeneration of the mammalian heart aiming at epicardium-derived cells.
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- 2012
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6. Protocol for a definitive, multi-centre, randomised controlled trial of Individual Placement and Support for people with alcohol and drug dependence
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Colocassis K, Jonathan Knight, Paul Anders, Quinn D, Clark H, Jez Stannard, Wright, John Marsden, Alexandra Melaugh, and Brian Eastwood
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Protocol (science) ,medicine.medical_specialty ,Randomized controlled trial ,law ,business.industry ,Alcohol and drug ,Physical therapy ,Medicine ,Multi centre ,business ,law.invention - Abstract
BACKGROUND : Unemployment is highly prevalent in populations with alcohol and drug dependence and current employment support is ineffective. Individual Placement and Support (IPS) is an evidence-based intervention for competitive employment. IPS has been extensively studied with people with severe mental illness and physical disabilities, but there have been no formal randomised controlled trials in alcohol and drug dependence. The Individual Placement and Support for Alcohol and Drug Dependence (IPS-AD) trial will determine definitively the effectiveness and cost effectiveness of IPS for patients with alcohol use disorder (AUD), opioid use disorder (OUD) and other drug use disorders.DESIGN/METHODS: The IPS-AD trial is a seven-site, pragmatic, two-arm, parallel group, superiority, randomised controlled trial, with an independent process evaluation. Eligible patients – all enrolled in ongoing community treatment in England for AUD, OUD and other drug use disorders (adult, unemployed or economically inactive for at least 6 months and wishing to obtain open job market employment) – will be randomised (1:1) to receive standard employment support (treatment-as-usual [TAU]) or TAU and IPS for nine months with up to four months of in-work support. The primary outcome measure will be competitive employment status (at least one day [7 hours]) during an 18-month follow-up, determined by patient-level, trial data-linkage with national tax and state benefit databases. With an 18% target difference (for the IPS intervention), and a two-sided 5% level of statistical significance, a minimum target sample of 832 participants will give 90% power for a pre-specified, mixed-effects, multi-variable logistic regression model, using a maximum-likelihood multiple imputation approach to manage missing outcome data. IPS-AD has seven vocational secondary outcome measures: total time in competitive employment (and corresponding National Insurance contributions and tax paid); time from randomisation to first competitive employment; number of competitive job appointments; job tenure (length of longest held competitive employment); sustained employment (tenure in a single appointment for at least 13 weeks); and job search self-efficacy. A cost-benefit and cost-effectiveness analysis will be done using the primary and secondary vocational outcomes, along with a set of secondary alcohol and drug treatment-related and social and health outcomes and their associated reference costs. The study process evaluation will address complementary questions of IPS implementation and delivery.DISCUSSION : The IPS-AD trial is the first large-scale, superiority randomised controlled trial of IPS for people with alcohol and drug dependence. The study will provide definitive evidence for the effectiveness and cost-effectiveness of the IPS model and will have substantial implications for service delivery. TRIAL REGISTRATION : ISRCTN Registry, ISRCTN24159790. Registered on 1 February 2018.KEYWORDS : Individual Placement and Support, alcohol, opioids, drugs, dependence.
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- 2019
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7. Deletion of Fstl1 (Follistatin-Like 1) From the Endocardial/Endothelial Lineage Causes Mitral Valve Disease
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Maurice J.B. van den Hoff, Luis J.J. Borreguero, Fereshte Rezai, Quinn D. Gunst, Marc Sylva, Lorena Flores Ruiz, Stuti Prakash, José Luis de la Pompa, Jan M. Ruijter, Medical Biology, Graduate School, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction & Development (AR&D), and ACS - Heart failure & arrhythmias
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0301 basic medicine ,Cardiac function curve ,medicine.medical_specialty ,Epithelial-Mesenchymal Transition ,Follistatin-Related Proteins ,Time Factors ,Endothelium ,Biology ,Ventricular Function, Left ,03 medical and health sciences ,Ventricular Dysfunction, Left ,Heart Conduction System ,Transforming Growth Factor beta ,Internal medicine ,Mitral valve ,medicine ,Animals ,Cell Lineage ,Genetic Predisposition to Disease ,cardiovascular diseases ,Endocardium ,Cell Proliferation ,Heart Failure ,Mice, Knockout ,Atrioventricular valve ,Mitral regurgitation ,Mitral Valve Prolapse ,Integrases ,Ventricular Remodeling ,Endothelial Cells ,Mitral Valve Insufficiency ,medicine.disease ,Receptor, TIE-2 ,Disease Models, Animal ,030104 developmental biology ,medicine.anatomical_structure ,Phenotype ,Heart failure ,Bone Morphogenetic Proteins ,Cardiology ,Disease Progression ,cardiovascular system ,Mitral Valve ,Cardiology and Cardiovascular Medicine ,Heart failure with preserved ejection fraction ,Signal Transduction ,Transcription Factors - Abstract
Objective— Fstl1 (Follistatin-like 1) is a secreted protein that is expressed in the atrioventricular valves throughout embryonic development, postnatal maturation, and adulthood. In this study, we investigated the loss of Fstl1 in the endocardium/endothelium and their derived cells. Approach and Results— We conditionally ablated Fstl1 from the endocardial lineage using a transgenic Tie2-Cre mouse model. These mice showed a sustained Bmp and Tgfβ signaling after birth. This resulted in ongoing proliferation and endocardial-to-mesenchymal transition and ultimately in deformed nonfunctional mitral valves and a hypertrophic dilated heart. Echocardiographic and electrocardiographic analyses revealed that loss of Fstl1 leads to mitral regurgitation and left ventricular diastolic dysfunction. Cardiac function gradually deteriorated resulting in heart failure with preserved ejection fraction and death of the mice between 2 and 4 weeks after birth. Conclusions— We report on a mouse model in which deletion of Fstl1 from the endocardial/endothelial lineage results in deformed mitral valves, which cause regurgitation, heart failure, and early cardiac death. The findings provide a potential molecular target for the clinical research into myxomatous mitral valve disease.
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- 2017
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8. Clinical Utility of Random Anti–Tumor Necrosis Factor Drug–Level Testing and Measurement of Antidrug Antibodies on the Long‐Term Treatment Response in Rheumatoid Arthritis
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Jani, Meghna, Chinoy, Hector, Warren, Richard B., Griffiths, Christopher E. M., Plant, Darren, Fu, Bo, Morgan, Ann W., Wilson, Anthony G., Isaacs, John D., Hyrich, KimmeL., Barton, Anne, Prouse, P. J., Moitra, R. K., Shawe, D. J., Nisar, M., Fairburn, K., Nixon, J., Barnes, T., Hui, M., Coady, D., Wright, D., Morley, C., Raftery, G., Bracewell, C., Bridges, M., Armstrong, D., Chuck, A. J., Hailwood, S., Kumar, N., Ashok, D., Reece, R., O'Reilly, S. C., Ding, T., Badcock, L. J., Deighton, C. M., Raj, N., Regan, M. R., Summers, G. D., Williams, R. A., Lambert, J. R., Stevens, R., Wilkinson, C., Kelly, C. A., Hamilton, J., Heycock, C. R., Saravanan, V., Cope, A., Garrood, T., Ng, N., Kirkham, B., Green, M., Gough, A., Lawson, C., Das, D., Borbas, E., Wazir, T., Emery, P., Bingham, S., Bird, H. A., Conaghan, P.G., Pease, C. T., Wakefield, R. J., Buch, M., Bruce, I., Gorodkin, R., Ho, P., Parker, B., Smith, W., Jenkins, E., Mukhtyar, C., Gaffney, K., Macgregor, A. J., Marshall, T., Merry, P., DeSilva, C., Birrell, F. N., Crook, P. R., Szebenyi, B., Bates, D., James, D., Gillott, T., Alvi, A., Grey, C., Browning, J., McHale, J. F., Gaywood, I.C., Jones, A. C., Lanyon, P., Pande, I., Doherty, M., Gupta, A., Courtney, P. A., Srikanth, A., Abhishek, A., Das, L., Pattrick, M., Snowden, H. N., Bowden, A. P., Smith, E. E., Klimiuk, P., Speden, D. J., Naz, S., Ledingham, J. M., Hull, R. G., McCrae, F., Cooper, A., Young‐Min, S. A., Wong, E., Shaban, R., Woolf, A. D., Davis, M., Hutchinson, D., Endean, A., Mewar, D., Tunn, E. J., Nelson, K., Kennedy, T. D., Dubois, C., Pauling, J., Korendowych, E., Jenkinson, T., Sengupta, R., Bhalla, A., McHugh, N., O'Neil, T., Herrick, A. L., Jones, A. K., Cooper, R. G., Dixon, W. G., Harrison, B., Buckley, C. D., Carruthers, D. C., Elamanchi, R., Gordon, P. C., Grindulis, K. A., Khattak, F., Raza, K., Situnayake, K., Akil, M., Till, S., Dunkley, L., Tattersall, R., Kilding, R., Tait, T., Maxwell, J., Kuet, K.-P., Plant, M. J., Clarke, F., Fordham, J. N., Tuck, S., Pathare, S. K., Paul, A., Marguerie, C. P., Rigby, S. P., Dunn, N., Abbas, I., Filer, C., Abernethy, V. E., Clewes, A. R., Dawson, J. K., Kitas, G., Erb, N., Klocke, R., Whallett, A. J., Douglas, K., Pace, A., Sandhu, R., John, H., Shand, L., Lane, S., Foster, H., Griffiths, B., Griffiths, I., Kay, L., Ng, W.-F., Platt, P. N., Walker, D. J., Peterson, P., Lorenzi, A., Friswell, M., Thompson, B., Lee, M., Pratt, A., Hopkinson, N. D., Dunne, C. A., Quilty, B., Marks, J., Mukherjee, S., Mulherin, D., Chalam, S. V., Price, T., Sheeran, T., Venkatachalam, S., Baskar, S., Al- Allaf, W., McKenna, F., Shah, P., Filer, A., Bowman, S. J., Jobanputra, P., Rankin, E. C., Allen, M., Chaudhuri, K., Dubey, S., Price‐Forbes, A., Ravindran, J., Samanta, A., Sheldon, P., Hassan, W., Francis, J., Kinder, A., Neame, R., Moorthy, A., Bukhari, M., Ottewell, L., Palkonyai, E., Hider, S., Hassell, A., Menon, A., Dowson, C., Kamath, S., Packham, J., Dutta, S., Price, S., Roddy, E., Paskins, Z., O'Reilly, D. T., Rajagopal, V., Bhagat, S., Chattopadhyay, C. B., Quinn, D., Isdale, A., Brown, A., Saleem, B., Foo, B., Al Saffar, Z., and Koduri, G.
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musculoskeletal diseases ,medicine.medical_specialty ,business.industry ,Immunology ,Arthritis ,Hydroxychloroquine ,Rheumatoid Arthritis ,medicine.disease ,Etanercept ,Surgery ,Rheumatology ,Sulfasalazine ,Internal medicine ,Rheumatoid arthritis ,medicine ,Adalimumab ,Immunology and Allergy ,Prospective cohort study ,business ,skin and connective tissue diseases ,Rheumatism ,medicine.drug - Abstract
Objective: To investigate whether antidrug antibodies and/or drug non-trough levels predict the long-term treatment response in a large cohort of patients with rheumatoid arthritis (RA) treated with adalimumab or etanercept and to identify factors influencing antidrug antibody and drug levels to optimize future treatment decisions. Methods: A total of 331 patients from an observational prospective cohort were selected (160 patients treated with adalimumab and 171 treated with etanercept). Antidrug antibody levels were measured by radioimmunoassay, and drug levels were measured by enzyme-linked immunosorbent assay in 835 serial serum samples obtained 3, 6, and 12 months after initiation of therapy. The association between antidrug antibodies and drug non-trough levels and the treatment response (change in the Disease Activity Score in 28 joints) was evaluated. Results: Among patients who completed 12 months of followup, antidrug antibodies were detected in 24.8% of those receiving adalimumab (31 of 125) and in none of those receiving etanercept. At 3 months, antidrug antibody formation and low adalimumab levels were significant predictors of no response according to the European League Against Rheumatism (EULAR) criteria at 12 months (area under the receiver operating characteristic curve 0.71 [95% confidence interval (95% CI) 0.57, 0.85]). Antidrug antibody–positive patients received lower median dosages of methotrexate compared with antidrug antibody–negative patients (15 mg/week versus 20 mg/week; P = 0.01) and had a longer disease duration (14.0 versus 7.7 years; P = 0.03). The adalimumab level was the best predictor of change in the DAS28 at 12 months, after adjustment for confounders (regression coefficient 0.060 [95% CI 0.015, 0.10], P = 0.009). Etanercept levels were associated with the EULAR response at 12 months (regression coefficient 0.088 [95% CI 0.019, 0.16], P = 0.012); however, this difference was not significant after adjustment. A body mass index of ≥30 kg/m2 and poor adherence were associated with lower drug levels. Conclusion: Pharmacologic testing in anti–tumor necrosis factor–treated patients is clinically useful even in the absence of trough levels. At 3 months, antidrug antibodies and low adalimumab levels are significant predictors of no response according to the EULAR criteria at 12 months.
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- 2015
9. Risk Factors for Suicide in a National Sample of Veterans With Multiple Sclerosis
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Steven L. Leipertz, Narineh Hartoonian, Aaron P. Turner, Quinn D. Kellerman, Jodie K. Haselkorn, Megan L. Beier, Trisha A. Hostetter, and Charles Maynard
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Adult ,Male ,Mental Health Services ,030506 rehabilitation ,medicine.medical_specialty ,Multiple Sclerosis ,Databases, Factual ,Psychological intervention ,Physical Therapy, Sports Therapy and Rehabilitation ,Alcohol use disorder ,National Death Index ,03 medical and health sciences ,0302 clinical medicine ,Sex Factors ,Risk Factors ,Cause of Death ,Medicine ,Humans ,Psychiatry ,Veterans Affairs ,Depression (differential diagnoses) ,Cause of death ,Aged ,Retrospective Studies ,Veterans ,business.industry ,Incidence ,Mental Disorders ,Rehabilitation ,Age Factors ,Odds ratio ,Middle Aged ,medicine.disease ,Survival Analysis ,United States ,Assessment of suicide risk ,Suicide ,United States Department of Veterans Affairs ,Case-Control Studies ,Multivariate Analysis ,Female ,0305 other medical science ,business ,030217 neurology & neurosurgery - Abstract
Objectives To examine risk factors in the year before suicide in a national sample of United States veterans with multiple sclerosis (MS), as well as means of suicide and receipt of mental health services prior to death. Design Case control study. Individuals in the Veterans Affairs MS National Data Repository were linked to the National Death Index Plus to obtain death records, including specific causes of death. Participants were veterans with MS who died by suicide and randomly selected nonsuicide MS controls (5 per participant) who were alive at the time of the index suicide. Mental health disorders and medical comorbidities were identified in the year before death for suicides and during the identical time period for controls. Setting Veterans Health Administration. Participants Veterans (N=426) who received treatment for MS in the United States Veterans Health Administration between 1999 and 2011. There were 71 deaths by suicide and 355 randomly selected controls. Interventions Not applicable. Main Outcome Measure Suicide. Results Results from the adjusted multivariable model suggest that the following factors were associated with an increased risk for suicide: male sex (odds ratio [OR], 3.60; 95% confidence interval [CI], 1.35-9.42), depression (OR, 1.82; 95% CI, 1.03-3.23), and alcohol use disorder (OR, 3.10; 95% CI, 1.38-6.96). Half (50.7%) had a mental health appointment in the year before suicide. The primary means of suicide was by firearm (62.0%). Conclusions Routine assessment of suicide risk in individuals with MS is warranted, particularly for those with recent history of depression or alcohol use disorder.
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- 2018
10. Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease within the ECLIPSE study
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Leeming, Diana J., Byrjalsen, Inger, Sand, Jannie M.B., Bihlet, Asger R., Lange, Peter, Thal-Singer, Ruth, Miller, Bruce E., Karsdal, Morten A., Vestbo, Jørgen, Ivanov, Y., Kostov, K., Bourbeau, J., Fitzgerald, M., Hernández, P., Killian, K., Levy, R., Maltais, F., O'Donnell, D., Krepelka, J., Vestbo, J., Wouters, E., Quinn, D., Bakke, P., Kosnik, M., Agusti, A., Sauleda, Jaume, Feschenko, Y., Gavrisyuk, V., Yashina, L., MacNee, W., Singh, D., Wedzicha, J., Anzueto, A., Braman, S., Casaburi, R., Celli, B., Giessel, G., Gotfried, M., Greenwald, G., Hanania, N., Mahler, D., Make, B., Rennard, S., Rochester, C., Scanlon, P., Schuller, D., Sciurba, F., Sharafkhaneh, A., Siler, T., and Silverman, E.
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Pulmonary and Respiratory Medicine ,Male ,Chronic bronchitis ,medicine.medical_specialty ,medicine.drug_class ,Collagen Type VI ,Collagen Type I ,Serology ,03 medical and health sciences ,Pulmonary Disease, Chronic Obstructive ,0302 clinical medicine ,Internal medicine ,Bronchodilator ,Forced Expiratory Volume ,Medicine ,Humans ,COPD ,030212 general & internal medicine ,Serological marker ,Lung function change ,Aged ,lcsh:RC705-779 ,biology ,business.industry ,Surrogate endpoint ,C-reactive protein ,lcsh:Diseases of the respiratory system ,Extracellular matrix ,respiratory system ,Middle Aged ,medicine.disease ,Prognosis ,Matrix Metalloproteinases ,Peptide Fragments ,respiratory tract diseases ,Clinical trial ,C-Reactive Protein ,030228 respiratory system ,biology.protein ,Observational study ,Female ,business ,Biomarkers ,Research Article - Abstract
Background Change in forced expiratory volume in one second (FEV1) is important for defining severity of chronic obstructive pulmonary disease (COPD). Serological neoepitope markers of collagen turnover may predict rate of change in FEV1. Methods One thousand COPD subjects from the observational, multicentre, three-year ECLIPSE (Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints) study (NCT00292552, trial registration in February 2006) were included. Matrix metalloproteinase (MMP)-generated fragments of collagen type I, and type VI (C1M and C6M) were assessed in month six serum samples. A random-coefficient model with both a random intercept and a random slope was used to test the ability of the markers to predict post-dose bronchodilator FEV1 (PD-FEV1) change over two years adjusting for sex, age, BMI, smoking, bronchodilator reversibility, prior exacerbations, emphysema and chronic bronchitis status at baseline. Results Annual change of PD-FEV1 was estimated from a linear model for the two-year study period. Serum C1M and C6M were independent predictors of lung function change (p = 0.007/0.005). Smoking, bronchodilator reversibility, plasma hsCRP and emphysema were also significant predictors. The effect estimate between annual change in PD-FEV1 per one standard deviation (1SD) increase of C1M and C6M was +10.4 mL/yr. and +8.6 mL/yr. C1M, and C6M, had a significant association with baseline FEV1. Conclusion We demonstrated that markers of tissue turnover were significantly associated with lung function change. These markers may function as prognostic biomarkers and possibly as efficacy biomarkers in clinical trials focusing on lung function change in COPD. Trial registration NCT00292552, Retrospectively registered, trial registration in February 2006. Electronic supplementary material The online version of this article (10.1186/s12890-017-0505-4) contains supplementary material, which is available to authorized users.
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- 2017
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11. Annals Story Slam - Voices of Medical Students and Residents: What Can Be Done to Build Trust
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Quinn D Bott
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Medical education ,Annals ,business.industry ,Internal Medicine ,Medicine ,General Medicine ,business ,Students medical - Published
- 2020
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12. Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes
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Holman, Rr, Bethel, Ma, Mentz, Rj, Thompson, Vp, Lokhnygina, Y, Buse, Jb, Chan, Jc, Choi, J, Gustavson, Sm, Iqbal, N, Maggioni, Ap, Marso, Sp, Öhman, P, Pagidipati, Nj, Poulter, N, Ramachandran, A, Zinman, B, Hernandez, Af, EXSCEL Study Group, : Califf RM, Patel, R, George, J, Sourij, H, Wong, Yw, Hannan, K, Sellers, Ma, Gottlieb, P, Lavender, P, Leloudis, D, Meadows, Y, Larson, D, Anderson, H, Elkins, M, Stone, A, Tisch, A, Perkins, L, Sanders, K, Campbell, C, Kennedy, I, Heal, P, Masterson, M, Darbyshire, J, Mumtaz, L, Athwal, R, Ferch, A, Batra, P, Durborow, L, Vincent, J, Woodall, A, Flanagan, T, Katona, B, Reicher, B, Pozzi, E, Oulhaj, A, Coleman, R, Rouleau, Jl, Pocock, Sj, Gorelick, F, Mcmurray, J, Riddle, M, Gagel, R, Collier, T, Markovic, T, Kong, Aps, Hian, Sk, Scott, R, Panelo, A, Yoon, Kh, Sheu, W, Sritara, P, Linong, J, Pan, C, Yong, H, Schernthaner, G, Mathieu, C, Tankova, T, Widimsky, P, Hanefeld, M, Keltai, M, Wainstein, J, del Prato, S, Pirags, V, Jakuboniene, N, Kooy, A, Dziemidok, P, Veresiu, Ia, Dreval, Av, Murin, J, Torello, Al, Sattar, N, Parkhomenko, O, Omar, M, Diaz, R, Lopes, R, Lanas, F, Urina Triana, M, Leiva-Pons, Jl, Aguliera, D, Bergenstal, R, Goodman, S, Yale, Jf, Caterson, I, Weng, J, Hu, D, Junbo, G, Zannad, F, Anoop, M, Ambrish, M, Gallegos, Ja, Green, Jb, Akerblom, A, Alexander, K, Al-Khatib, S, Armaganijan, L, Barros, P, Batit, M, Bernacki, G, Bernandez, S, Bloomfield, G, Clausen, E, De Souza Brito, F, Devore, A, Dombrowski, K, Eapen, Z, Gellad, Z, George, D, Guimaraes, P, Halim, S, Harrison, R, Hawes, J, Hess, C, Hyland, K, Jackson, L, Jones, S, Jordan, D, Katz, M, Kong, D, Koshizaka, M, Lakey, W, Leblanc, T, Leonardi, S, Luo, N, Mahaffey, K, Mandawat, A, Mehta, R, Melloni, C, Morse, M, Pagidpati, N, Patel, C, Patel, K, Pokorney, S, Posvic, T, Rao, M, Roe, M, Shah, B, Tillmann, H, Truffa, A, Zazula, A, Zeitler, E, Sicer, M, Ulla, Mr, Maffei, L, Klyver, Mi, Calella, P, Alvarisqueta, A, De La Fuente RL, Aizenberg, D, Roque, F, Cruciani, A, Frechtel, G, Gelersztein, E, Villarino, A, Mallagray, M, Nardone, L, Zaidman, C, Novaretto, L, Bartolacci, I, de Salvo, M, Delcourt, C, Crimmins, D, Jackson, R, O’Neal, D, Colman, P, Jeffries, W, Mah, Pm, Wittert, G, Proietto, J, Amerena, J, Marks, S, Tan, R, Colquhoun, D, Pieber, T, Drexel, H, Prager, R, Schnack, C, Hoppichler, F, Fasching, P, Francesconi, C, Luger, A, Schoenherr, Hr, Ebenbichler, C, Paulweber, B, Shernthaner, G, Verhaegen, A, Vanuytsel, J, Thissen, Jp, e Silva P, Barros, Gonzaga, C, Borges, J, Hissa, M, Rea, R, Rossi, P, Chacra, A, Eliaschewitz, F, Garbelini, B, Felicio, J, Rassi, N, Rossi, F, Nunes dos Santos, M, e Farias F, Bandeira, Lisboa, H, e Forti A, Costa, Saraiva, Jk, Kovacheva, S, Levterov, G, Sheinkova, G, Ilieva, E, Lyubenova, L, Damyanova, V, Gushterova, V, Mincheva, L, Illiev, D, Ivanov, V, Bobeva, R, Nikitov, Z, Shumkova, R, Lefterov, In, Zaharieva, S, Videva, V, Yakov, A, Cheung, S, Elliott, T, Mehta, P, Ross, S, Sigal, R, Woo, V, Jaffer, S, Kuritsky, R, Bell, A, Dumas, R, Gosselin, G, Robitaille, Y, Greenspoon, A, Lochnan, H, Tytus, R, Leiter, L, Pandey, A, Punthakee, Z, Dube, F, Sigalas, J, Pearce, M, Woodford, T, Paul, P, Bourgeois, R, Conway, R, Mazza, G, Hatheway, R, Misterski, J, Raffo, C, Olivares, C, Godoy, J, Potthoff, S, Santibañez, C, Larenas Yanez GJ, Gu, W, Shen, F, Ma, J, Guo, X, Li, Q, Du, Y, Hu, J, Ji, L, Li, Y, Deng, H, Feng, Y, Liu, L, Mu, Y, Ma, C, Qu, S, Wang, J, Wang, Y, Yuan, Z, Zhang, L, Zhou, S, Yang, T, Dong, Y, Liu, D, Coronel Arroyo, J, Perez Amador, G, Botero Lopes, R, Jaramilo, C, Orozco Linares, A, Cure Cure CA, Hernandez Triana, E, Molina de Salazar DI, Marin, Cr, Jaramilo Gomez CJ, Kellinerova, I, Adamkova, V, Krami, P, Brychta, T, Havelkova, J, Pantikova, K, Schoper, F, Pohl, W, Schumm-Draeger, Pm, Julius, U, Tschöpe, D, Hamann, A, Seissler, J, Schellong, S, Rose, L, Becker, B, Linn, T, Oerter, Em, Strotmann, Hj, Mölle, A, Pfutzner, A, Forst, T, Schäufele, T, Mugge, A, Lehrke, M, Meyer-Pannwitt, U, Mehling, H, Simon-Wagner, I, Schenkenberger, I, Busch, K, Hermes, S, Milek, K, Landers, B, Grueneberg, M, Braun, M, Nothroff, J, Kamke, W, Hergdt, G, Duengen, Hd, Kleinertz, K, Kuesters, D, Boenninghoff, Ah, Appel, Kf, Schaefer, A, Bieler, T, Ozaki, R, Luk, Aoy, Chu, Dw, Cheung-Wong, Mm, Siu, Dc, Yan, Bpy, Kung, K, Wong, Sys, Tsang, Cc, Yeung, Vt, Cheung, Bm, Tse, Hf, Hodi, G, Nagy, K, Lippai, J, Takacs, J, Fulop, T, Gaal, Z, Pauker, Z, Foldesi, I, Simon, J, Oroszan, T, Futo, L, Bezzegh, K, Nagy, A, Vandorfi, G, Kiss, J, Kesmarki, N, Kis, E, Papp, A, Kovacs, A, Szakal, I, Palinkas, A, Czegany, Z, Voros, P, Reiber, I, Kerenyi, Z, Dezso, E, Wittman, I, Penzes, J, Ples, Z, Taller, A, Farago, K, Kis, Jt, Zilahi, Z, Molnar, M, Barkai, L, Mileder, M, Szentpeteri, I, Peterfai, E, Lovasz, O, Mosenzon, O, Minuchin, O, Jaffe, A, Vishlitsky, V, Shimon, I, Bashkin, A, Stern, N, Elias, N, Bental, T, Butnaru, A, Lewis, B, Adawi, F, Nseir, W, Klainman, E, Herskovits, T, Cignarelli, M, Rotella, Cm, Ambrosio, G, Pozzilli, P, Genovese, S, Cavarape, A, Salvioni, A, Sokolova, J, Strautina, I, Teterovska, D, Stalte, V, Pastare, S, Leitane, I, Lagzdina, L, Andersone, I, Eglite, R, Stelmane, I, Levinger, A, Barsiene, L, Sulskiene, M, Varanauskiene, E, Danyte, E, Urbanaviciene, E, Urbanavicius, V, Zabuliene, L, Juskiene, R, Velaviciene, A, Kakariekiene, V, Augusteniene, A, Velickiene, D, Lasiene, J, Dauksiene, D, Caponis, J, Tan, At, Ramanathan, L, Hassan, Mra, Tan, F, Ong, Tk, Foo, Sh, Ghani, Ra, Cheah, Wk, Sanchez Mijangos JH, Cabrera Jardines, R, Barrientos Perez, M, Sauque Reyna, L, Alcocer Gamba MA, Villeda Espinosa, E, Tamez Perez HE, De La Garza Hernandez NE, Lopes, Sm, Ramirez Diaz SP, Reyes Sanchez, R, Márquez-Rodriguez, E, Köse, V, Voors-Pette, C, Oldenburg-Ligtenberg, Pc, van Kempen WW, Cox, K, Hoogendyk, J, Swinkels-Diepenmaat, L, Rojas-Lingan, G, Kentgens, S, Schipperen, S, de Valk HW, Swart, H, van Bemmel, B, Hoogslag, Pam, Diamant, M, Serné, Eh, Hamer, A, Wilson, S, Fisher, N, Dixon, P, Chaudhri, O, Crawford, V, Quinn, D, Nirmalaraj, K, Dunn, P, Gillies, J, Cutfield, R, Krebs, J, Helm, C, Kerr, J, Pryke, J, Ebo, G, Denopol, M, Ang, E, Uy, N, Jimeno, C, Mirasoi, R, Paz Pacheco, E, Custodio, M, Nicodemus, N Jr, Catindig, Ea, Magno, M, Tirador, L, Cylkowska, B, Stasinksa, T, Silwinska, T, Sroka, M, Piepiorka, M, Korzeniak, R, Mirecka, H, Zaluska, R, Pupek-Musialik, D, Homenda, W, Grabowska, A, Okopien, B, Niegowska, J, Pogorzelska, H, Mikolajczyk-Swatko, A, Sikorski, M, Sowinski, D, Tahk, Sj, Kim, Yn, Nam, Cw, Rim, Sj, Kim, Cj, Choi, Km, Lee, Ik, Kim, Ij, Namgung, J, Moon, Kw, Kim, Ks, Oh, Bh, Lee, Wy, Choi, Sh, Kim, Es, Moon, S, Mindrescu, Nm, Aron, G, Graur, M, Hancu, N, Mlitaru, C, Nafornita, V, Szilagyi, I, Popa, Ar, Angelescu, Lm, Negrisanu, Gd, Zaharie, Dg, Culman, Mi, Vacaru, G, Munteanu, M, Constantinescu, S, Tivadar, S, Dreval, A, Barbarash, O, Strongin, L, Dogadin, S, Suplotova, L, Izmozherova, N, Marasaev, V, Khokhlov, A, Repin, A, Turova, E, Bondar, I, Samoylova, Y, Sherenkov, A, Smolenskaya, O, Zrahevskiy, K, Koshelskaya, O, Obrezan, A, Dzupina, A, Stevlik, J, Buganova, I, Pella, D, Vinanska, D, Jascur, J, Micko, K, Sosovec, D, Philippiova, A, Olexa, P, Fedacko, J, Selecky, J, Nicolau, J, Mediavilla Garcia, J, Botella Serrano, M, Lecube, A, Arguelles, I, Sabán, J, Gómez Cerezo, F, Soto, A, Bellido, D, Sucunza Alfonso, N, Vendrell Ortega, J, Alvarez, L, Garcia Puig, J, Angustias Quesada, M, Contreras Gilbert, J, Almeida, Ca, Tinahones, Fj, Garcia Ortiz, L, Gómez Marcos MA, Aomar, I, Fernández Balsells, M, Distiller, L, Padayachee, T, Badat, A, Ebrahim, I, Naiker, P, Ranjith, N, Kelfkens, Y, Makan, H, Mogashoa, S, Fulat, M, Carim-Ganey, N, Coetzee, K, Govender, T, Nortje, H, Wilhase, A, Seedat, S, Gani, M, Ellis, G, Rheeder, P, Wing, J, Blignaut, S, Kaplan, H, Lottering, H, Pillai, P, Louw, C, Coetzer, T, Sheu, Whh, Chen, Jf, Yang, Cy, Tseng, St, Wang, Cy, Lai, Wt, Hung, Yj, Hsieh, Ic, Su, Sl, Pei, D, Benjasuratwong, Y, Purewal, T, Milward, A, Dimitropoulos, I, Kumar, S, Barber, T, Wiles, P, Dang, C, Adler, A, Philip, S, Bellary, S, Price, D, Oelbaum, R, Heller, S, Sathayapalan, T, Clark, J, Leese, G, Simpson, H, Kilvert, A, Dawson, A, Hall, T, Takhar, A, Bundy, C, Harvey, P, Maxwell, S, Asamoah-Owusu, Nj, Mcknight, J, Chatterjee, S, Calvert, J, Wright, A, Macrury, S, Macfarlane, D, Johnson, A, Litchfield, J, Field, B, Koval, O, Larin, O, Levchenko, O, Martynyuk, L, Maslyanko, V, Rudyk, I, Suprun, Y, Tseluyko, V, Botsyurko, V, Vatutin, M, Fushtey, I, Grishyna, O, Kuskalo, P, Panina, S, Pererva, L, Prysupa, L, Teliatnikova, Z, Sokolova, L, Vlasenko, M, Berenfus, V, Gyrina, O, Kopytsya, M, Vizir, V, Vayda, M, Shanik, M, Headapohl, D, Pahl, J, Aronoff, S, Bartkowiak, A Jr, Chang, A, Gaudiani, L, Kayne, D, Look, M, Patel, N, Moran, J, Stout, E, Tsao, J, Struble, R, Fishman, N, Rodbard, H, Lucas, K, Dugano-Daphnis, P, Merrick, B, Nadar, V, Severa, L, Sorli, C, Chang, M, Reed, J III, Grunberger, G, Bain, C, Bestermann, W Jr, Morawski, E, White, J, Azizad, M, Ukwade, P, Anekwe, A, Jimenez, A, Weiss, D, Green, S, Overcash, J, Eaton, C, Roseman, H, Soler, N, Mikell, F, Manos, P, Levinson, L, Claxton, E Jr, Weiss, R, Argoud, G, Bickel, L, Wilson, J, Short, B, Webster, B, Mcneill, R, Schnall, A, Force, R, Phillips, L, Bybee, K, Forker, A, Denham, D, Vonderhaar, T, Pullman, J, Kruger, D, Whitehouse, F, Wysham, C, Baron, M, Kravitz, A, Dushkin, H, Manning, Mb, Wine, A, Jaffrani, N, Chadha, C, Sperl-Hillen, J, Busch, R, Estevez, R, Robbins, D, Rassouli, N, Garvey, T, Oparil, S, Eckel, R, Mcdermott, M, Rasouli, N, Mcgill, J, Corder, C, Klonoff, D, Mills, R, Earl, J, Kessel, J, Cuddihy, R, Zimmerman, R, Dayamani, P, Oral, E, Zimering, M, Marks, J, Farnsworth, K, Sugimoto, D, Toth, P, Bhargava, A, Mcguire, D, Rohatgi, A, Davies, M, Peden, E, Wyne, K, Alfonso, L, Seyoum, B, Akpunonu, B, Feinglos, M, Reaven, P, Soule, J, Luttrell, L, Schactman, B, Canadas, R, Boggs, B, Abbott, L, Herring, C, Roberts, L, Hage-Korban, E, Schubart, U, Taylon, A, Tannenbaum, A, Kingsley, J, Lenhard, J, Biscoveanu, M, Cohen, J, Donovan, D, Laferrere, B, Thompson, N, Wade, T, Detweiler, R, Henson, B, White, A, Cavale, A, Ravi, C, Thomas, A, Goodman, H, Kalen, V, Fox, D, Dauber, I, Rizvi, S, Marcus, A, Mulford, M, Higgins, A, Chane, M, Bland, V, Osunkoya, A, Suresh, D, Khan, S, Anastasi, L, Bajaj, M, Eisen, H, Mudaliar, Sr, Powell, S, Carr, K, Tripathy, D, Azad, N, Wakefield, P, Acheatel, R, Bressler, P, Dean, J, El Shahawy, M, Gilbert, J, Haque, I, Humiston, D, Ison, R, Karounos, D, Lillestol, M, Ferrier, N, Labroo, A, Vo, A, D’Agostino, R, Dulin, M, Mcwilliams, A, Hargrove, J, Blumberg, E, Jackson, B, Staniloae, C, Salacata, A, Hidalgo, H Jr, Nicol, P, Digiovanna, M, Soufer, J, Mahabadi, V, Akinboboye, O, Arauz-Pacheco, C, Neutel, J, Dungan, K, Benson, M, Powell, T, Gandy, W, Rovner, S, Berk, M, Khan, A, Ledesma, G, Madu, I, Erickson, B, Radbill, M, Graves, M, Kaczmarek, G, Giep, S, Baldauf, C, Golden, G, Lesh, K, Davis, C, Godbole, N, Kirby, W, Razzaque, N, Bhatt, B, Wilson, M., Internal medicine, ACS - Diabetes & metabolism, and ACS - Microcirculation
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Male ,medicine.medical_specialty ,EXSCEL Study Group ,Injections, Subcutaneous ,030209 endocrinology & metabolism ,Type 2 diabetes ,Kaplan-Meier Estimate ,030204 cardiovascular system & hematology ,Placebo ,Article ,Drug Administration Schedule ,GLP1-agonists ,03 medical and health sciences ,0302 clinical medicine ,Double-Blind Method ,Interquartile range ,Internal medicine ,Diabetes mellitus ,General & Internal Medicine ,medicine ,Humans ,Hypoglycemic Agents ,Least-Squares Analysis ,Aged ,Glycated Hemoglobin ,business.industry ,Venoms ,Semaglutide ,Incidence ,Type 2 diabetes, GLP1-agonists, exenatide, cardiovascular effects ,General Medicine ,11 Medical And Health Sciences ,Middle Aged ,medicine.disease ,Surgery ,Albiglutide ,Editorial ,Diabetes Mellitus, Type 2 ,Cardiovascular Diseases ,Exenatide ,Dulaglutide ,Female ,business ,Peptides ,cardiovascular effects ,medicine.drug - Abstract
BACKGROUND: The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown. METHODS: We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extended-release exenatide at a dose of 2 mg or matching placebo once weekly. The primary composite outcome was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. The coprimary hypotheses were that exenatide, administered once weekly, would be noninferior to placebo with respect to safety and superior to placebo with respect to efficacy. RESULTS: In all, 14,752 patients (of whom 10,782 [73.1%] had previous cardiovascular disease) were followed for a median of 3.2 years (interquartile range, 2.2 to 4.4). A primary composite outcome event occurred in 839 of 7356 patients (11.4%; 3.7 events per 100 person-years) in the exenatide group and in 905 of 7396 patients (12.2%; 4.0 events per 100 person-years) in the placebo group (hazard ratio, 0.91; 95% confidence interval [CI], 0.83 to 1.00), with the intention-to-treat analysis indicating that exenatide, administered once weekly, was noninferior to placebo with respect to safety (P
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- 2017
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13. Endothelial follistatin-like-1 regulates the postnatal development of the pulmonary vasculature by modulating BMP/Smad signaling
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I. Sophie T. Bos, Wim Timens, H. Maarsingh, Luis Jesús Jiménez-Borreguero, Quinn D. Gunst, Reinoud Gosens, Martina Schmidt, Stuti Prakash, Andrea Mattiotti, Navessa Padma Tania, Maurice J.B. van den Hoff, Molecular Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Medical Biology, Graduate School, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction & Development (AR&D), and ACS - Heart failure & arrhythmias
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0301 basic medicine ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Vascular smooth muscle ,Endothelium ,endothelium ,Bone morphogenetic protein ,MICE LACKING ,03 medical and health sciences ,Internal medicine ,bone morphogenetic protein ,medicine ,HEREDITARY HEMORRHAGIC TELANGIECTASIA ,KINASE-1 GENE ,Research Articles ,GENE-EXPRESSION ,Tube formation ,biology ,Endothelin-1 ,business.industry ,Endoglin ,Endothelin 1 ,Endothelial stem cell ,BINDING-PROTEIN ,030104 developmental biology ,medicine.anatomical_structure ,Endocrinology ,II RECEPTOR ,Jagged1 ,Immunology ,biology.protein ,ARTERIAL-HYPERTENSION ,ARTERIOVENOUS-MALFORMATIONS ,GLA PROTEIN-DEFICIENCY ,business ,Follistatin - Abstract
Bone morphogenetic protein (BMP) signaling regulates vascular smooth muscle maturation, endothelial cell proliferation, and tube formation. The endogenous BMP antagonist Follistatin-like 1 (Fstl1) is highly expressed in pulmonary vascular endothelium of the developing mouse lung, suggesting a role in pulmonary vascular formation and vascular homeostasis. The aim of this study was to investigate the role of Fstl1 in the pulmonary vascular endothelium. To this aim, Fstl1 was conditionally deleted from endothelial and endothelial-derived cells using Tie2-cre driven Fstl1-KO mice (Fstl1-eKO mice). Endothelial-specific Fstl1 deletion was postnatally lethal, as ∼70% of Fstl1-eKO mice died at three weeks after birth. Deletion of Fstl1 from endothelium resulted in a reduction of right ventricular output at three weeks after birth compared with controls. This was associated with pulmonary vascular remodeling, as the percentage of actin-positive small pulmonary vessels was increased at three weeks in Fstl1-eKO mice compared with controls. Endothelial deletion of Fstl1 resulted in activation of Smad1/5/8 signaling and increased BMP/Smad-regulated gene expression of Jagged1, Endoglin, and Gata2 at one week after birth compared with controls. In addition, potent vasoconstrictor Endothelin-1, the expression of which is driven by Gata2, was increased in expression, both on the mRNA and protein levels, at one week after birth compared with controls. At three weeks, Jagged1 was reduced in the Fstl1-eKO mice whereas Endoglin and Endothelin-1 were unchanged. In conclusion, loss of endothelial Fstl1 in the lung is associated with elevated BMP-regulated genes, impaired small pulmonary vascular remodeling, and decreased right ventricular output.
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- 2017
14. Effect of a Behavioral Self-Regulation Intervention on Patient Adherence to Fluid Intake Restrictions in Hemodialysis: A Randomized Controlled Trial
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M. Bryant Howren, Jamie A. Cvengros, William J. Lawton, Alan J. Christensen, Quinn D. Kellerman, and Stephen L. Hillis
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Adult ,Male ,Pediatrics ,medicine.medical_specialty ,medicine.medical_treatment ,030232 urology & nephrology ,Drinking ,Article ,law.invention ,Self-Control ,03 medical and health sciences ,Fluid intake ,0302 clinical medicine ,Randomized controlled trial ,law ,Behavior Therapy ,Renal Dialysis ,Intervention (counseling) ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Renal Insufficiency, Chronic ,General Psychology ,Aged ,business.industry ,Medical record ,Middle Aged ,medicine.disease ,Psychiatry and Mental health ,Health psychology ,Treatment Outcome ,Patient Compliance ,Female ,Hemodialysis ,medicine.symptom ,business ,Weight gain ,Kidney disease - Abstract
The purpose of this study is to evaluate the efficacy of a behavioral self-regulation intervention vs. active control condition using a parallel-group randomized clinical trial with a sample of center hemodialysis patients with chronic kidney disease. Participants were recruited from 8 hemodialysis treatment centers in the Midwest. Eligible patients were (a) fluid nonadherent as defined by an interdialytic weight gain >2.5 kg over a 4-week period, (b) >18 years of age, (c) English-speaking without severe cognitive impairment, (d) treated with center-based hemodialysis for >3 months, and (e) not living in a care facility in which meals were managed. Medical records were used to identify eligible patients. Patients were randomly assigned to either a behavioral self-regulation intervention or active control condition in which groups of 3–8 patients met for hour-long, weekly sessions for 7 weeks at their usual hemodialysis clinic. Primary analyses were intention-to-treat. Sixty-one patients were randomized to the intervention while 58 were assigned to the attention-placebo support and discussion control. Covariate-adjusted between-subjects analyses demonstrated no unique intervention effect for the primary outcome, interdialytic weight gain (β = 0.13, p = 0.48). Significant within-subjects improvement over time was observed for the intervention group (β = −0.32, p = 0.014). The present study found that participation in a behavioral self-regulation intervention resulted in no unique intervention effect on a key indicator of adherence for those with severe chronic kidney disease. There was, however, modest within-subjects improvement in interdialytic weight gain for the intervention group which meshes with other evidence showing the utility of behavioral interventions in this patient population. ClinicalTrials.gov Identifier: NCT01066949
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- 2016
15. Palivizumab prophylaxis of respiratory syncytial virus disease in 2000-2001: Results from the palivizumab outcomes registry
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Guillermin J, Freutner S, Cohen S, Cassino D, Benoit M, Carroll C, Wingate J, Batiz E, Blum, Rowen J, Guedes B, Chavarria C, Clay Smith, Busey A, Barton Wj, Nowatzke P, Sarnosky K, Goessler M, Romero J, Geiss D, Gley M, Milla P, Sadeghi H, Swafford C, Boron Ml, Rojas S, Hensley S, Farrell L, Hirsch Rl, Kelly T, Boland J, Mink Jw, Walsh J, Martin S, Douglas G, Speer M, Sokunbi Ma, Sorrentino M, Aaronson A, Bentler J, Hunter, Burleson L, Habersang R, Zanni R, Hand I, Stanford A, Booth T, Mackey K, Marcus M, Rzepka Aa, McCall M, McRae P, Davis R, Ghaffari K, Guclu L, Wolsztein J, Emmanuel B. Walter, Shank K, Rouse K, Shah R, Simon W. Lewis, Lovett N, Bolling C, Parnes C, Schmucker J, Wilkinson L, Fuentes S, Free T, Fishbein J, Hirsch D, Johnson C, Komendowski K, Chawla, Quintin A, Lawson Sm, Benbow M, Stephen A. Chartrand, Rhodes T, Rowley R, Sullivan M, Richardson L, Colby L, Riordan L, Lee H, Zinno, Ledbetter J, Prater M, Marshall, Andrew Gelfand, Cyrus S, Cross M, Calcagno Ja, Minard C, Young C, Seybold K, F T Weber, Hayes C, Bennett E, DeBonnett L, McFarland K, Combs K, Butler S, Smeltzer D, Naranjo M, Atkinson La, Harris Ka, Airington S, Richard N, Schochet P, Ortiz M, Arispe E, Frogel M, Protter P, Lemm D, Thompson P, Unfer S, Gatti A, Quinn D, Nicholes P, Roach J, Joyave J, Copenhaver S, Van Veldhuisen Pc, Beverly P. Giordano, Botts T, Cyrus J, Eki C, Halpin Gj, Zuniga M, Fetter-Zarzeka A, Pane C, Case E, Muraligopal, Walker L, van Houten J, Deckard M, Nerwen C, Haskett K, Hudak M, Linehan D, Buchin D, and Raby D
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Male ,Pulmonary and Respiratory Medicine ,Palivizumab ,Pediatrics ,medicine.medical_specialty ,Population ,Respiratory Syncytial Virus Infections ,Disease ,Virus diseases ,Antibodies, Monoclonal, Humanized ,Antiviral Agents ,Risk Factors ,Outcomes Registry ,medicine ,Humans ,Prospective Studies ,Registries ,Respiratory system ,Prospective cohort study ,education ,education.field_of_study ,business.industry ,Antibodies, Monoclonal ,Infant ,Hospitalization ,Treatment Outcome ,Pediatrics, Perinatology and Child Health ,Gestation ,Female ,business ,medicine.drug - Abstract
The objective of the Registry was to characterize the population of infants receiving prophylaxis for respiratory syncytial virus (RSV) disease by describing the patterns and scope of usage of palivizumab in a cross section of US infants. RSV hospitalization outcomes were also described. The Palivizumab (Synagis, MedImmune, Inc., 25 West Watkins Mill Road, Gaithersburg, MD 20878) Outcomes Registry was a prospective multicenter survey conducted at 63 sites. Demographics, injection history, and RSV hospitalization outcomes were collected on 2,116 infants receiving palivizumab. Infants were enrolled in the Registry between September 1, 2000-March 1, 2001, at the time of their first injection. Infants born at less than 32 weeks of gestation accounted for 47% of infants enrolled, and those between 32-35 weeks accounted for 45%; approximately 8% were greater than 35 weeks of gestation. Lower RSV hospitalization rates were observed in infants who had greater adherence to regularly scheduled injections. Nearly one-half of all hospitalizations occurred within the first and second injection intervals, suggesting the importance of early RSV protection. The confirmed RSV hospitalization rate of all infants in the Registry was 2.9%; the rate was 5.8% in infants with chronic lung disease of infancy, and 2.1% in premature infants without chronic lung disease. In conclusion, these data support the continued effectiveness of palivizumab prophylaxis for severe RSV lower respiratory tract disease in a large cohort of high-risk infants from geographically diverse pediatric offices and clinics. The Palivizumab Outcomes Registry provides an opportunity to assess palivizumab utilization and clinical effectiveness in the US.
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- 2003
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16. Depression in Chronic Kidney Disease
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Alan J. Christensen, Julia R. Van Liew, and Quinn D. Kellerman
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medicine.medical_specialty ,business.industry ,Internal medicine ,medicine ,medicine.disease ,business ,Depression (differential diagnoses) ,Kidney disease - Abstract
Chronic kidney disease (CKD) is a prevalent medical condition posing a range of unique physical and self-management demands for patients and presenting a variety of patient management challenges for clinicians. Co-morbid depression and other psychiatric disorders represent a significant detriment to the quality of life and clinical outcomes of CKD patients. Evidence suggests that 12% to 40% of individuals in the later stages of CKD meet DSM (III, IV, or IV-TR) diagnostic criteria for a mood disorder. Moreover, the existence of comorbid depression has been associated with earlier patient mortality. Depression assessment is itself complicated by the physiologic and medical treatment status of the patient, and depression is believed to be both underdiagnosed and undertreated in this population. Rigorous empirical demonstrations of the safety and/or efficacy of both pharmacologic and nonpharmacologic treatments for depression are limited for this population. However, a number of important factors that should be considered in treating depression in kidney disease patients have been identified. This chapter summarizes these and other key clinical recommendations relevant to the evaluation and treatment of co-morbidity of depression in this population.
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- 2014
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17. Cardiac regeneration from activated epicardium
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Antoon F.M. Moorman, Bram van Wijk, Quinn D. Gunst, Maurice J.B. van den Hoff, Cardiothoracic Surgery, ACS - Amsterdam Cardiovascular Sciences, Medical Biology, and ARD - Amsterdam Reproduction and Development
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medicine.medical_specialty ,Embryology ,Histology ,Mesenchyme ,Population ,Ischemia ,Myocardial Infarction ,lcsh:Medicine ,Biology ,Cardiovascular ,Polymerase Chain Reaction ,Cell Fate Determination ,Mice ,Internal medicine ,Molecular Cell Biology ,medicine ,Myocyte ,Animals ,Regeneration ,Myocytes, Cardiac ,cardiovascular diseases ,education ,lcsh:Science ,Zebrafish ,In Situ Hybridization ,education.field_of_study ,Multidisciplinary ,Regeneration (biology) ,Myocardium ,Mesenchymal stem cell ,lcsh:R ,Heart ,Cell Differentiation ,Molecular Development ,medicine.disease ,biology.organism_classification ,Embryonic stem cell ,Signaling ,Cell biology ,Morphogens ,medicine.anatomical_structure ,Cardiology ,cardiovascular system ,Medicine ,lcsh:Q ,Pericardium ,Research Article ,Developmental Biology - Abstract
In contrast to lower vertebrates, the mammalian heart has a very limited regenerative capacity. Cardiomyocytes, lost after ischemia, are replaced by fibroblasts. Although the human heart is able to form new cardiomyocytes throughout its lifespan, the efficiency of this phenomenon is not enough to substitute sufficient myocardial mass after an infarction. In contrast, zebrafish hearts regenerate through epicardial activation and initiation of myocardial proliferation. With this study we obtain insights into the activation and cellular contribution of the mammalian epicardium in response to ischemia. In a mouse myocardial infarction model we analyzed the spatio-temporal changes in expression of embryonic epicardial, EMT, and stem cell markers and the contribution of cells of the Wt1-lineage to the infarcted area. Though the integrity of the epicardial layer overlaying the infarct is lost immediately after the induction of the ischemia, it was found to be regenerated at three days post infarction. In this regenerated epicardium, the embryonic gene program is transiently re-expressed as well as proliferation. Concomitant with this activation, Wt1-lineage positive subepicardial mesenchyme is formed until two weeks post-infarction. These mesenchymal cells replace the cardiomyocytes lost due to the ischemia and contribute to the fibroblast population, myofibroblasts and coronary endothelium in the infarct, and later also to the cardiomyocyte population. We show that in mice, as in lower vertebrates, an endogenous, epicardium-dependent regenerative response to injury is induced. Although this regenerative response leads to the formation of new cardiomyocytes, their number is insufficient in mice but sufficient in lower vertebrates to replace lost cardiomyocytes. These molecular and cellular analyses provide basic knowledge essential for investigations on the regeneration of the mammalian heart aiming at epicardium-derived cells.
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- 2012
18. The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis
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Vivian S. W. Li, Maurice J.B. van den Hoff, Hans Clevers, Anita A. A. Buffing, Marc Sylva, Saskia van der Velden, Maaike van den Born, Quinn D. Gunst, Antoon F.M. Moorman, Johan H. van Es, Jan Harm Koolstra, Neuroscience Campus Amsterdam - integrative Analysis & Modeling, Research Institute MOVE, Mathematics, Faculteit der Geneeskunde, Orale Celbiologie (ORM, ACTA), ACS - Amsterdam Cardiovascular Sciences, Medical Biology, Other departments, ARD - Amsterdam Reproduction and Development, Oral Cell Biology, and Hubrecht Institute for Developmental Biology and Stem Cell Research
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Male ,Pathology ,Anatomy and Physiology ,Mouse ,Organogenesis ,Respiratory System ,Limb Development ,Regulator ,Gene Expression ,Mice ,Morphogenesis ,Lung ,Musculoskeletal System ,Zebrafish ,Mice, Knockout ,Multidisciplinary ,biology ,Embryo ,Animal Models ,Cell biology ,Bone Morphogenetic Proteins ,embryonic structures ,Medicine ,Female ,Research Article ,medicine.medical_specialty ,Follistatin-Related Proteins ,animal structures ,Science ,SOX9 ,Model Organisms ,SDG 17 - Partnerships for the Goals ,Genetics ,medicine ,Animals ,Birth Defects ,Muscle, Skeletal ,Biology ,Endochondral ossification ,Mesenchymal stem cell ,Molecular Development ,biology.organism_classification ,Signaling ,Mice, Inbred C57BL ,biology.protein ,Skeletal Development ,Developmental Biology ,Follistatin - Abstract
Follistatin-like 1 (Fstl1) is a secreted protein of the BMP inhibitor class. During development, expression of Fstl1 is already found in cleavage stage embryos and becomes gradually restricted to mesenchymal elements of most organs during subsequent development. Knock down experiments in chicken and zebrafish demonstrated a role as a BMP antagonist in early development. To investigate the role of Fstl1 during mouse development, a conditional Fstl1 KO allele as well as a Fstl1-GFP reporter mouse were created. KO mice die at birth from respiratory distress and show multiple defects in lung development. Also, skeletal development is affected. Endochondral bone development, limb patterning as well as patterning of the axial skeleton are perturbed in the absence of Fstl1. Taken together, these observations show that Fstl1 is a crucial regulator in BMP signalling during mouse development. [KEYWORDS: Animals, Bone Morphogenetic Proteins/ antagonists & inhibitors, Female, Follistatin-Related Proteins/genetics/ metabolism, Lung/ embryology/ metabolism, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Muscle, Skeletal/ embryology/ metabolism, Organogenesis/genetics/ physiology]
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- 2011
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19. Association between depressive symptoms and mortality risk in chronic kidney disease
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Alan J. Christensen, Quinn D. Kellerman, Austin S. Baldwin, and William J. Lawton
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Male ,medicine.medical_specialty ,Disease ,Article ,Risk Factors ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Risk factor ,Prospective cohort study ,Applied Psychology ,Depression (differential diagnoses) ,Proportional Hazards Models ,Proportional hazards model ,business.industry ,Depression ,Mortality rate ,Public health ,Middle Aged ,medicine.disease ,Iowa ,Surgery ,Psychiatry and Mental health ,Multivariate Analysis ,Kidney Failure, Chronic ,Female ,business ,Kidney disease - Abstract
Previous examinations of depression as a predictor of mortality in end-stage renal disease have yielded inconsistent findings. We sought to clarify the possible link with mortality by assessing depression at an earlier stage of renal impairment before the uremic disease state and depressive symptoms become highly confounded, and then following patients during the period of disease progression.Prospective design using an assessment of depression before initiation of renal replacement therapy to predict mortality status an average of 81 months later in patients in the early stages of chronic kidney disease.Mortality status.After controlling for relevant mortality risk factors (i.e., age, gender, presence of diabetes and cardiovascular disease, and potassium level), results of Cox regression analyses indicated that higher levels of nonsomatic depression symptoms were predictive of an increased mortality risk, χ²(1, N = 359) = 8.02, p = .005. Patients with nonsomatic depression scores 1 SD above the mean had an estimated mortality rate 21.4% higher than average scorers in this sample.Clinical implications of these findings point to the importance of assessment and treatment of depressive symptoms in patients with chronic kidney disease.
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- 2010
20. Feasibility and utility of an electronic diary to assess self-report symptoms in patients with inflammatory bowel disease
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Leighann Litcher-Kelly, Quinn D. Kellerman, Arthur A. Stone, and Stephen B. Hanauer
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Adult ,Male ,medicine.medical_specialty ,MEDLINE ,Protocol Deviation ,Pilot Projects ,Inflammatory bowel disease ,Electronic diary ,Medical Records ,Crohn Disease ,Recall bias ,medicine ,Humans ,In patient ,General Psychology ,Aged ,business.industry ,Medical record ,Middle Aged ,medicine.disease ,Psychiatry and Mental health ,Health psychology ,Computers, Handheld ,Physical therapy ,Feasibility Studies ,Patient Compliance ,Colitis, Ulcerative ,Female ,business ,Software - Abstract
Background: Self-report items from the Crohn’s Disease Activity Index (CDAI) are completed using a 7-day paper diary; however, there are reports of protocol deviations by both patients and researchers/clinicians. The self-report literature has demonstrated these deviations can distort the information collected by introducing recall bias, especially for subjective measures like pain and well-being.Purpose: The purpose of this pilot study is to evaluate the feasibility of using an electronic diary to collect symptom self-reports.Methods: Sixteen patients with Inflammatory Bowel Disease completed entries on the diary 12 times per day for 3 weeks. The diary included “user-friendly” features that made it easier to incorporate into their daily lives.Results: Despite 2 compliance outliers, the overall compliance was 88%; when these outliers were removed compliance increased to 92%. Participants used the diary features appropriately and completed a substantial number of assessments per day. Although overall compliance declined significantly over the 3-week study period, the number of prompts completed did not change significantly over time.Conclusions: Limitations include the small sample size, but despite this limitation this report supports the feasibility of collecting symptom information using an electronic diary. Future studies are needed to evaluate the possibility of using an electronic diary to collect the CDAI self-report information in both clinical and research settings.
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- 2007
21. 555Cardiac regeneration from activated epicardium
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Quinn D. Gunst, M. J. B. Van Den Hoff, Andy Wessels, and A Van Wijk
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education.field_of_study ,medicine.medical_specialty ,Endothelium ,Physiology ,Regeneration (biology) ,Population ,Mesenchymal stem cell ,Ischemia ,Infarction ,Biology ,medicine.disease ,Embryonic stem cell ,Cell biology ,medicine.anatomical_structure ,Physiology (medical) ,Internal medicine ,cardiovascular system ,medicine ,Cardiology ,cardiovascular diseases ,Cardiology and Cardiovascular Medicine ,education ,Myofibroblast - Abstract
The mammalian heart has a very limited regenerative capacity. Cardiomyocytes, lost after ischemia, are replaced by fibroblasts. Although the human heart is able to form new cardiomyocytes throughout its lifespan, the efficiency of this phenomenon is not enough to substitute sufficient myocardial mass after an infarction. In contrast, zebrafish hearts regenerate through epicardial activation and initiation of myocardial proliferation. We have used the mWt1/IRES/GFP-Cre mouse line to trace the fate of epicardial derived cells during development and subsequently used this line to obtain insights into the activation and cellular contribution of the epicardium in response to ischemia. Epicardial derived cells (EPDCs) start to populate the ventricular myocardium from E12 onward. Remarkably the EPDCs only populate the compact layer and it is only at the end of gestation that the EPDCs invade the trabecular myocardium. Within the developing myocardium the myocardium the EPDCs also contribute to a subset of the coronary endothelial cells and perivascular fibroblasts. In this mouse model we subsequently induced a myocardial infarction and analyzed the spatio-temporal changes in expression of embryonic epicardial, EMT, and stem cell markers and the contribution of the epicardial-lineage to the infarcted area. Immediately after the myocardial infarction the integrity of the epicardial layer overlaying the infarct is lost. The epicardium was found to regenerate within three days post infarction. In this regenerated epicardium, the embryonic gene program is transiently re-expressed as well as proliferation. Concomitant with this activation, EPDCs are formed until two weeks post-infarction. These EPDCs initially form a thick layer in between the newly fromed epicardium and ischemic myocardium. Subsequently, these mesenchymal cells replace the cardiomyocytes lost due to the ischemia and contribute to the fibroblast population, myofibroblasts and coronary endothelium in the infarct. From one month post infarction onward a small number of lineage postive cardiomyocytes is found within the infarcted zone. We show that the contribution of epicardial derived cells to the froming ventricle and that an endogenous, epicardium-dependent regenerative response to injury is induced. Although this regenerative response leads to the formation of new cardiomyocytes, their number is insufficient. These molecular and cellular analyses provide basic knowledge essential for investigations on the regeneration of the mammalian heart aiming at epicardium-derived cells.
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- 2014
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22. P315Wt1 regulates the expression of inhibitory chemokines during heart development
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M. J. B. Van Den Hoff, You-Ying Chau, Manuel Reina, Fernando O. Martinez, Victor Velecela, Nicholas D. Hastie, Laura A. Lettice, Quinn D. Gunst, and Ofelia M. Martínez-Estrada
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congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Heart morphogenesis ,Heart development ,urogenital system ,Physiology ,fungi ,Cell migration ,Biology ,urologic and male genital diseases ,female genital diseases and pregnancy complications ,CCL5 ,Cell biology ,Paracrine signalling ,Chemokine receptor ,Endocrinology ,Physiology (medical) ,Internal medicine ,medicine ,CXCL10 ,Signal transduction ,Cardiology and Cardiovascular Medicine - Abstract
The embryonic epicardium is an important source of cardiovascular precursor cells and paracrine factors that are required for adequate growth and complete formation of the heart. WT1 is expressed in the embryonic and neonatal heart in mammals; however it becomes quiescent in the adult heart. Recently, a great deal of attention has been given to the signalling pathways regulated by WT1 that promote heart development. It has been demonstrated that WT1 can regulate epicardial EMT and the release of growth factors; however there is little information on the signalling pathways regulated by WT1 that could act in a negative manner. Transcriptome analysis of Wt1KO epicardial cells reveals an unexpected role for WT1 in repressing the expression of interferon-regulated genes that could be involved in a negative regulation of heart morphogenesis. We showed that WT1 is required to repress the expression of the chemokines Ccl5 and Cxcl10 in epicardial cells. We observed an inverse correlation of Wt1 and the expression of Cxcl10 and Ccl5 during epicardium development. Chemokine receptor analyses of hearts from Wt1(gfp/+) mice demonstrate the differential expression of their chemokine receptors in GFP(+) epicardial enriched cells and GFP(-) cells. Functional assays demonstrate that CXCL10 and CCL5 inhibit epicardial cell migration and the proliferation of cardiomyocytes respectively. WT1 regulates the expression levels of Cxcl10 and Ccl5 in epicardial cells directly and indirectly through increasing the levels of IRF7. As epicardial cell reactivation after myocardial damage is linked with WT1 expression, the present work has potential implications in the field of adult heart repair.
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- 2014
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23. Enfortumab vedotin after PD-1 or PD-L1 inhibitors in cisplatin-ineligible patients with advanced urothelial carcinoma (EV‑201): a multicentre, single-arm, phase 2 trial
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Janet Trowbridge, Peter H. O'Donnell, Arjun Vasant Balar, Joyce Steinberg, Evan Y. Yu, Jae-Lyun Lee, Mark N. Stein, Andrea Necchi, Michael R. Harrison, Daniel P. Petrylak, Shang-Ying Liang, Bradley Alexander McGregor, Se Hoon Park, David I. Quinn, Michiel S. van der Heijden, Mary Campbell, Yohann Loriot, Takahiro Kojima, Jonathan E. Rosenberg, Elisabeth I. Heath, Yu, E. Y., Petrylak, D. P., O'Donnell, P. H., Lee, J. -L., van der Heijden, M. S., Loriot, Y., Stein, M. N., Necchi, A., Kojima, T., Harrison, M. R., Hoon Park, S., Quinn, D. I., Heath, E. I., Rosenberg, J. E., Steinberg, J., Liang, S. -Y., Trowbridge, J., Campbell, M., Mcgregor, B., and Balar, A. V.
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0301 basic medicine ,Adult ,Male ,medicine.medical_specialty ,Urologic Neoplasms ,Metastatic Urothelial Carcinoma ,Adolescent ,medicine.medical_treatment ,Programmed Cell Death 1 Receptor ,Enfortumab vedotin ,Phases of clinical research ,Neutropenia ,B7-H1 Antigen ,Disease-Free Survival ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Clinical endpoint ,Humans ,Adverse effect ,Immune Checkpoint Inhibitors ,Response Evaluation Criteria in Solid Tumors ,Aged ,Chemotherapy ,business.industry ,Carcinoma ,Antibodies, Monoclonal ,Middle Aged ,medicine.disease ,Gene Expression Regulation, Neoplastic ,030104 developmental biology ,Oncology ,030220 oncology & carcinogenesis ,Cisplatin ,Urothelium ,business ,Cell Adhesion Molecules - Abstract
Summary Background Locally advanced or metastatic urothelial carcinoma is generally incurable and has scarce treatment options, especially for cisplatin-ineligible patients previously treated with PD-1 or PD-L1 therapy. Enfortumab vedotin is an antibody–drug conjugate directed at Nectin-4, a protein highly expressed in urothelial carcinoma. We aimed to evaluate the efficacy and safety of enfortumab vedotin in the post-immunotherapy setting in cisplatin-ineligible patients. Methods EV-201 is a multicentre, single-arm, phase 2 study of enfortumab vedotin in patients with locally advanced or metastatic urothelial carcinoma previously treated with PD-1 or PD-L1 inhibitors. Cohort 2 included adults (aged ≥18 years) with an Eastern Cooperative Oncology Group performance status score of 2 or less who were considered ineligible for cisplatin at enrolment and who had not received platinum-containing chemotherapy in the locally advanced or metastatic setting. Enfortumab vedotin was given intravenously at a dose of 1·25 mg/kg on days 1, 8, and 15 of every 28-day cycle. The primary endpoint was confirmed objective response rate per Response Evaluation Criteria in Solid Tumours version 1.1 assessed by blinded independent central review. Efficacy and safety were analysed in all patients who received at least one dose of enfortumab vedotin. EV-201 is an ongoing study and the primary analysis is complete. This study is registered with Clinicaltrials.gov , NCT03219333 . Findings Between Oct 8, 2017, and Feb 11, 2020, 91 patients were enrolled at 40 sites globally, of whom 89 received treatment. Median follow-up was 13·4 months (IQR 11·3–18·9). At data cutoff (Sept 8, 2020), the confirmed objective response rate was 52% (46 of 89 patients; 95% CI 41–62), with 18 (20%) of 89 patients achieving a complete response and 28 (31%) achieving a partial response. 49 (55%) of 89 patients had grade 3 or worse treatment-related adverse events. The most common grade 3 or 4 treatment-related adverse events were neutropenia (eight [9%] patients), maculopapular rash (seven [8%] patients), and fatigue (six [7%] patients). Treatment-related serious adverse events occurred in 15 (17%) patients. Three (3%) patients died due to acute kidney injury, metabolic acidosis, and multiple organ dysfunction syndrome (one [1%] each) within 30 days of first dose and these deaths were considered by the investigator to be related to treatment; a fourth death from pneumonitis occurred more than 30 days after the last dose and was also considered to be related to treatment. Interpretation Treatment with enfortumab vedotin was tolerable and confirmed responses were seen in 52% of cisplatin-ineligible patients with locally advanced or metastatic urothelial carcinoma who were previously treated with PD-1 or PD-L1 inhibitors. These patients have few treatment options, and enfortumab vedotin could be a promising new therapy for a patient population with a high unmet need. Funding Astellas Pharma Global Development and Seagen.
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- 2021
24. A universal standard for the validation of blood pressure measuring devices: Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Collaboration Statement
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Alan Murray, Martin Myers, Richard J McManus, Thomas Graßl, Neil Atkins, John P. A. Ioannidis, Gerhard N. Frick, Bruce A. Friedman, George S. Stergiou, Paolo Palatini, Siegfried Eckert, Andrew Shennan, Bruce S. Alpert, David I. Quinn, Takashi Usuda, Stephan Mieke, Josh Sarkis, Eoin O'Brien, Colin O. Wu, Ji-Guang Wang, Tsutomu Ichikawa, Gianfranco Parati, Roland Asmar, Peter S. Lacy, Stergiou, G, Alpert, B, Mieke, S, Asmar, R, Atkins, N, Eckert, S, Frick, G, Friedman, B, Graßl, T, Ichikawa, T, Ioannidis, J, Lacy, P, Mcmanus, R, Murray, A, Myers, M, Palatini, P, Parati, G, Quinn, D, Sarkis, J, Shennan, A, Usuda, T, Wang, J, Wu, C, and O'Brien, E
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medicine.medical_specialty ,Engineering ,Consensus ,Standardization ,Physiology ,blood pressure measurement ,International Cooperation ,Iso standards ,Validation Studies as Topic ,030204 cardiovascular system & hematology ,Article ,Medical instrumentation ,03 medical and health sciences ,0302 clinical medicine ,Internal Medicine ,medicine ,Humans ,Medical physics ,030212 general & internal medicine ,protocol ,Reference standards ,device ,Societies, Medical ,Protocol (science) ,Statement (computer science) ,validation ,Blood pressure monitors ,accuracy ,business.industry ,Reproducibility of Results ,standard ,blood pressure ,Blood Pressure Determination ,Guideline ,Reference Standards ,Sphygmomanometers ,Blood Pressure Monitors ,Europe ,Fully developed ,Blood pressure ,monitor ,Research Design ,Practice Guidelines as Topic ,Hypertension ,Cardiology and Cardiovascular Medicine ,business - Abstract
Copyright © 2018 Wolters Kluwer Health, Inc., and American Heart Association, Inc. This article has been copublished in Hypertension. In the last 30 years, several organizations, such as the US Association for the Advancement of Medical Instrumentation (AAMI), the British Hypertension Society, the European Society of Hypertension (ESH) Working Group on Blood Pressure (BP) Monitoring and the International Organization for Standardization (ISO) have developed protocols for clinical validation of BP measuring devices. However, it is recognized that science, as well as patients, consumers and manufacturers would be best served if all BP measuring devices were assessed for accuracy according to an agreed single validation protocol that had global acceptance. Therefore, an international initiative was taken by AAMI, ESH and ISO experts who agreed to develop a universal standard for device validation. This statement presents the key aspects of a validation procedure, which were agreed by the AAMI, ESH and ISO representatives as the basis for a single universal validation protocol. As soon as the AAMI/ESH/ISO standard is fully developed, this will be regarded as the single universal standard and will replace all other previous standards/protocols.
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- 2018
25. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
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S. Artigas, A V Dreval, Mark I. McCarthy, C Watson, Peter H. Bennett, M Quint, Y Ikeda, E Alpert, F Schiele, H Sekihara, Erik Gylfe, P Lowe, J Kuhlmann, Alain Golay, V Longo, Shahidul Alam Khan Akm., L G Mantovani, M Zawodniak-Szalapska, G Winkler, T Harrity, L Virág, U Johne, Kuo S-W., Linda C Tapsell, J Rodriguez, Michel Komajda, K Kankova, Carole A. Cull, M Sporna, E Estilles, U Ribel, M C Spruce, E Buzzigoli, T Prazak, J K McLaughlin, M K Lingohr, M Lim, F Calara, A Siebenhofer, G Meregalli, Roberto Anichini, A D Baron, R Kurashvili, P C Butler, G I Fantus, T. E. De Gooyer, Park Y-M., R. Walther, S Heinrich, Agnieszka Zawiejska, S Mukherjee, Nikolaos Papanas, G Wong, Ian D. Caterson, David M. Maahs, Shuichi Kaneko, Alexandra E. Butler, Francisco Javier Ampudia-Blasco, O N Kong, Attali J-R., C A Hedman, K Oshinyemi, Nicolle Müller, I C Cranston, N Okumus, M V Vlaiculescu, Balasubramanian Ravikumar, W W Cheatham, K Mukasa, K B Biswas, Annunziata Lapolla, Phil McEwan, G Mader, Gilles Chassot, Dragi Anevski, Werner A. Scherbaum, M Donath, C Hesselmann, R A Gandhi, David E. Moller, Ezio Bonifacio, C Garcia, V Ifandi, P Hornnes, Nieuwenhoven Fav., C Puech, S Pérez-Del-Pulgar, Kim S-R., G Hines, C Rubio Terrés, Michael Gaster, N. Hosszufalusi, A Scholze, Andrew A. Young, Stavros Liatis, F Hariri, S Tan, Paul Valensi, Allan E. Karlsen, J Kim, E. Moberg, J Kaiser, L Berman, G Nelson, A Altkrüger, P Kothare, D B Cook, S Doran, G. van Dijk, Shahnaz Shahinfar, Kim C-S., P Stahl, M Manousaki, S Sigrist, S K Lim, M. P. Stern, A Guberti, C Rezzani, J McKenney, Karl Thomaseth, Sofia Carlsson, M Julia, R Brillante, I Rubesova, T Darkow, E Matsumoto, Wendy M. Macfarlane, M Di Martino, G Bardini, Rossella Menghini, D Duhot, E Farcasiu, Annalisa Natalicchio, I Lindner, J Buvat, Christian L. Brand, Harry Dorchy, Iwona Pietrzak, Z T Luo, P Home, M Ekelund, Jesper Gromada, Kristine Færch, F Piarulli, H Kim, R Mentel, Zsuzsanna K. Zsengellér, Dullaart Rpf., Anton Luger, Thomas A. Pearson, V Manicardi, P Rösen, Feng Y-M., R Morganti, Lars Hansen, Demuth H-U., Haruo Kasai, A Shostak, Rudi Steffensen, G Taylor, Markolf Hanefeld, C Santini, E Hamaguchi, Roberto Miccoli, F Storms, M Cooper, Y Lee, Allison E. Aiello, P Smith, T Suehiro, K Treece, M Waluś, Timothy A Welborn, Simone Baltrusch, E Kontela, S Chai, J Crean, H Yokoyama, Johan G. Eriksson, Rafael Hernández Hernández, J Rodríguez-Saldaña, M P Tornero, G Formoso, D. Lovell, E Bingham, A Mylonakis, M Manteghetti, D Fedele, Antonio Martín-Duce, Ralph A. DeFronzo, D Salcedo, Kurt Højlund, Antonio Petrone, Sheu Whh., C Gutierrez, Flavia Pricci, S Kurita, Z G Abbas, M M Benedetti, Philippe A. Halban, Daniel J. Cox, O Ljungkvist, Justine Davies, J Palsgaard, Lars Sjöström, E Bosi, L Janin-Manificat, W. F. Kelly, M. Fernandez, E Colak, O V Mulyarchik, B Kronshage, F Lang, M Erfurth, Takashi Kadowaki, N Jendrike, U Walter, J Wishart, Y. Neye, D Kim, N Furuhashi, M Barsotti, D Florow, L Ke, L Borgquist, N C Jackson, Ffolliott M. Fisher, V Baskar, K Yoshioka, Bryan A. Wolf, G Chabrier, R Skoumal, Livio Luzi, H Kose, I Pharisien, B. Klein, H Winiarska, M C Johnson, L Griffiths, Nonna Kravchun, C Combe, Baptist Gallwitz, J Zdychova, L Skorda, Jorma Ilonen, W Gao, I N Steen, A Terrinoni, P D Ambery, W Kern, C M Kusminski, Cho M-H., Paolo Pozzilli, Louise G. Grunnet, E Schönle, David R Matthews, Robert W. Taylor, Y Cohen, Kim H-S., M P Eccles, N B Tutuncu, D McDowell, Richard M. Bergenstal, K Takamatsu, T Steiner, Jaan Palgi, Valdemar Grill, N Niculescu, G Federici, S Lehto, P. M. McKeigue, M Barone, Michael E. Trautmann, S Smirnov, J Mannion, M Eto, C Rousseau, M Conti, C S Ernest, Antonio Ceriello, D H Schweitzer, Jung E-D., Andreas Festa, Avijit Lahiri, A Shepelkevich, A Murro, A Kollmann, Jonathan R.S. Arch, R Landgraf, Son H-Y., I Engelsberger, E Agardh, S Rodríguez-Mulero, P J Kraml, K Lee, D. F. Du Toit, E Kim, G Fadini, Williams Ajk., Philip Home, M B Antcieferov, C Perlemoine, D Perrea, Song X-L., D Ruggieri, Krister Bokvist, Heidi Sørensen, Bilbao, G Yoshino, J P Taylor, Shen H-M., S M Furier, R Urquhart, J Wohlgelernter, Jianping Weng, T. Baba, Q Hong, C Silva, Castaigne J-P., M Felaco, X X Zhang, M Jaroň, Milla Rosengård-Bärlund, J G Papp, Toshio Miyata, Lervang H-H., Park M-K., I Kinalska, A Long, Oomen Phn., N Kogawa, Ippolita Patrizia Patera, S. Karadeniz, Dinesh Selvarajah, D S Chung, A Wensaas, Richard Imrich, M Recasens, J Ruxer, O Buchea, E Wilpart, S P Stepanenko, Le Ttd., H Ohgawara, Mariaconsuelo Valentini, A Mondok, M Peltonen, Marianne O. Larsen, K Chatzianagnostou, Agneta Ståhle, A L Ferrari, L Bordier, F Maingrette, A Matsuda, G Vukomanovic, Jakob D. Wikstrom, T Yamakita, E Gorostiaga, J Jin, B Gopalan, Heinz Drexel, S Hewitt, Rury R. Holman, C Dieterle, T L Ruchti, N Asatiani, M Sidira, A Iezzi, A J Sommerfield, D Châtenet, M L Olsen, R Bergemann, C Koehler, T L Kuraeva, B Balas, Christian Berne, E Santos-Mazo, G Smith, A Siejka, R Kožnarová, A Mattina, S Sheikh, A Adomeit, M Rasmussen, J. Fagerudd, N Busciantella Ricci, Nuria Vilarrasa, E Hammar, T L Thoms, L Aydın, Ron G. Rosenfeld, A Nikolajuk, R Gos, C L Morgan, H L Yu, D Dheelchand, S Ramrath, N Boudriga, Jerome I. Rotter, C Jahannault, W M Weston, Folke Lindgärde, M Hertlova, D Knight, A Monroy-Mayorga, E Pardini, A Chamson-Reig, B Franke, Janie McCluskey, Joseph Bryan, C Nikolopoulou, Christie M. Ballantyne, Fausto Santeusanio, L Pegoraro, M Lee, A Klimenko, S Jaiveer, K. Pettersson-Fernholm, Michael A. Nauck, A Ekbom-Schnell, G Deferrari, Riccardo Schiaffini, S. Pampanelli, Khan Aka., David Hopkins, Maija Wessman, M Kamarinos, Noh J-H., O Ebisui, K McCarroll, Jeppe Sturis, Peter Nowotny, N Gorbenko, Åke Sjöholm, David G. Maggs, A E Halseth, B Cresci, A A Ortiz-Gress, A Korakovouni, O Matejkova, C E Mogensen, C J Lin, Ramon Gomis, H Seaman, C Granier, Yang C-H., F Assah, O Sanchez, Fausto Machicao, Peter G. Morris, Alberto Ortiz, A Giardinelli, D Bracaglia, A Gonzalo, S Pavlatos, Andreas Lechner, F Canovic, L Sjolind, Allan Vaag, Birgitte Bruun Nielsen, David A. Ziegler, Vito Lampasona, R Gershoni-Baruch, A. Dei Cas, H Renz, E Mena, Matthew Waltham, Kim D-M., H Levanen, D D Mick, Valentina Alexandrovna Peterkova, E Meskhishvili, Sarah Nutland, R Bustani, John R. Lindsay, M Christoforidou, A Abicht, E Harno, K Cyganek, A Fitchet, S Neelotpol, P Nikishin, P Serradas, J Hinrichsen, M Halvorson, M Chovatia, B Voet, Jinny Willis, E Parretti, M Haslbeck, M Wellard, L Teng, Julio Wainstein, J S Fischer, K. Lalic, D Roggenland, I Gich, R Anwar, Maurizio Cassader, D Serota, X J Li, R J Schotzinger, Vilmundur Gudnason, Björn Zethelius, S A Wootton, W Andrzejewski, R Rezsohazy, R Gao, T Klimentova, T Mazurek, I Bruckner, C Dohrmann, R E James, G daSilva Xavier, Kim S-Y., A Dorca, Stuart J. Pocock, Terri J. Allen, I Giovos, P B Parab, N H Andersen, P Fotinakis, Miriam Cnop, H Lee, Norbert Tennagels, Omorodola I. Abatan, F Ailett, I. Lager, D Manzella, H Hut, Larry A. Distiller, G Lip, Lim S-K., Rong Zhang, T Tsuno, Steen Knudsen, M. Bajardi, Manuel Benito, Dai Sugimoto, Melvin J. Prince, D W Dunstan, D Rankins, K A Majali, G Ozansoy, Isabella Russo, S Uçak, G Annuzzi, R Talar-Wojnarowska, K Lange, S Neugebauer-Baba, Campbell H. Thompson, Eric Renard, P. D. Mountjoy, Z Morrison, Elizabeth A. Davis, Franco Cavallo, C Corvaja, R Antuña, Craig John Currie, H Linnebjerg, He Y-L., A J Palmer, Mariola R. Chacón, H Malinska, M. Jones, R Lichnovská, K Mandes, Paolo Tessari, T Mokhort, A Laina, H. L. Y. Chan, I Schmidt, R Banks, Richard G. IJzerman, L Ksinantova, G Setti, H Vaudry, A Gallo, V Spallone, Chen J-W., Thomas Danne, A Chong, M Hallschmid, S Aczel, S Hulme, N Islam, M Hosoi, P M Ternan, P Di Bartolo, N Bishara, T Shibasaki, Martin A. Osterhoff, Im S-S., M Jecht, T Hamaguchi, S Mattera, K Ways, Elizabeth Northam, U Rajala, Reinhard W. Holl, L Yang, S Panaiotopoulos, K Horvath, R Kluge, Thora B. Bodvarsdottir, Y Dong, Irene Alemanno, C McDougall, Reimar W. Thomsen, M Campbell, W Rabl, John Öhrvik, Yuichiro Yamada, Paola Ungaro, W Benzer, Mike Sampson, Roberto Trevisan, R G Radu, Aas A-M., P E Lobo, Ricardo Scott, S M Son, Josephine M. Forbes, T A Hillier, K L Wyne, Louis L. Nguyen, J Farmer, M H Tan, Kwon H-S., J Yang, L Sandvik, Franco Folli, A K Jenum, M Nguyen, W Pratipanawatr, A L Frederiksen, Rebecca Smith, Lee H-J., A Schäfer, C Manuelli, G S Denver, T Vukovich, B Maceira, K Matsumoto, K. Chokkalingam, Nurcan Üçeyler, P Modi, Timothy M. Morgan, S Mertens, B M Singh, Michaela Riedl, K Iso, C Cucurullo, G. F. Bottazzo, M Calvani, K Hur, J Wetzels, Kazuhiro Takahashi, Y Aso, H Stammer, M G Masding, Fitsum Guebre-Egziabher, J L González-Sánchez, L Armstrong, Alberto Maran, Peter G.F. Swift, S S Popovic, J Starczynski, E Vitacolonna, Luigi Laviola, R W Gelling, Marina Cardellini, D Barilla, Rosa de Diego Martínez, W H Landschulz, Anne Mette Rosenfalck, R K Wong, Kevin E. Schneider, K Peros, Giuseppe Nanni, F Zhang, I Rákóczi, T Iburi, M Nakhjavani, X Q Zhang, S Tournis, Per Lav Madsen, Graham A. Hitman, A. Tura, K Laubner, N D Kostic, Lawrence M. Dolan, R. Sinha Roy, J A Wagner, J. Tuomilehto, J Hauptman, M Abdel-Ghany, D Lacombe, Toralph Ruge, Johannes A Maassen, Triantafyllos Didangelos, K Sasaki, I Argüelles, Klaus Levin, C Popow, Emanuel Christ, R Chetty, L Baillet-Blanco, Jo-Ann Salmon, T Mine, James L. Trevaskis, I Franke, J Gorski, E A Andrianova, A Dayan, A Caballero, Aleksandra Gilis-Januszewska, M Yasujima, Z Kasalová, C.D.A. Stehouwer, F. K. Gorus, G A Nichols, A Glowania, David P. Strachan, P Fredlund, N. F. da Silva, P Reboldi, M Sausbier, K H Groenier, G Stuccio, N Guttman, K R Ahmed, A D Ristic, T Kapellen, J Coutcher, Aldo V. Greco, Oswald Wagner, A Zagayko, Maria Alevizaki, B B Zhang, W F Ferris, Jenny Fredriksson, Lois Jovanovic, J Hänninen, R De Giglio, Kazuo Yagui, O Potterat, P Hamliton, R E Scranton, B Mankovsky, A Stylianou, B Fellström, Abdel-Wahab Yha., M Kitagawa, Katherine L. Baldock, F R Johnson, F Baigts, S D'Addato, F J Sanz, A Mistry, S D Wise, T Pratipanawatr, U R Fölsch, James R.C. Parkinson, Claudia Sommer, C Park, F E Griffiths, M L Martí, R Demirtunc, S Taniguchi, J Lundkvist, T Siegmund, Juan Sztajzel, C Dienesch, F Baumgartner, L Scalone, T M Mckolanis, K Otake, Ullrik Pedersen-Bjergaard, T M Vriesendorp, Michael B. Wheeler, Henry Schmitt, Peter Hovind, S Lange, Stephane Roze, L. Van Gaal, B Klaproth, Anthony E. Civitarese, D Eckland, A Dagar, D F Hopkins, Kari Stefansson, C Gonzalez-Yanes, B Meyboom-de Jong, D. J. Betteridge, K Buhling, M Crepaldi, Ana M. Wägner, L Renna, L Volpe, R McBride, V Corbo, E O Brennesvik, R P Hayes, R Abdollahnia, G Viviani, C F Liew, Francisco Pérez-Bravo, Jeffrey Baron, Brian M. Frier, H H Samira, D Szentendrei, K. J. Schjoedt, W K Waldhäusl, D Gniuli, D Zou, G Tschank, V Urbančič, A L Nolan, Albertini J-P., J Malcomson, M Larbig, C Cheyssac, K Aurich, C M Kesson, S Heller, Maija E. Miettinen, R F Luco, Adrian J. Cameron, Luigi Mattiello, Z. Metelko, X E Zhang, M Parramón, I. G. Obrosova, J Fruchart, M Ilic, Björn Eliasson, Gilles Chatellier, M A Martín, D M Kendall, Holger Luthman, V F Varillas, D Maccubbin, Jang S-A., Amalia Gastaldelli, E Salzsieder, P. de Mol, A Yoshida, H D Lindner, D Gostiljac, M Just, Pan C-Y., J M Fujitaki, G Eiermann, K Bergenheim, A D Frick, A Agacdiken, K Varytimiadis, K Cseh, D A Jackson, S Calderari, Dena G. Hernandez, H M Liebich, K Min, F. de Zegher, Bernd Kulzer, K Han, Ulrich A. Müller, D Marrero, H Hatakeyama, René Koopman, Doo H-K., Petr Wohl, P. Sharp, P Forder, Thor Aspelund, N Meneveau, R M Schmülling, R Aubert, Thom Sam., H Youshikawa, M Ankelo, D Bowden, I Kelly, Frédéric Fumeron, M Sartini, Robert S. Sherwin, L Varadhan, A Criscimanna, John Betteridge, V Jelic, M Bartnik, N Lemke, B Ursø, A Bertoldo, A M Owona, H Okochi, L Pérez-Tamajó, S L Monfre, Daniel Brandhorst, K T Legg, Andries J. Smit, Veronica Sancho, Masashi Hirai, C Klein, Paul J. Thornalley, A Chaidaroglou, K Miura, B Zinman, O M Dvoynishnikova, J Plank, Jan Bolinder, C Lush, B Rubi, R Pozzilli, M Bashir, S A Shtandel, F Mosca, A Naskalska, Josef Vcelak, U Sausbier, P Cavaiani, T U Baehring, Michele Solimena, P Formisano, M Rastaldi, Bernard Thorens, J Ruzzin, E Arbit, M. Hori, Torkel B. Brismar, E Soltes Rak, A Filo, P Heinke, Matthew P. Coghlan, M Masotti, I Perevozskaya, K Ahn, I Moules, K Van Dyck, I Goldstein, Z Mathe, G Z Zhao, S Fajardo, J Taylor, S Chrul, J C Pareja, D Hadjidakis, A J Scheen, N Siddiqua, D C Cavan, R Grella, Krabbe S, H J Rochlitz, A E Hinkkanen, W Wilpshaar, Richard Stevens, M Dreyer, S Hara, X Wang, Melania Manco, D Gillen, Magalie A. Ravier, Olli Simell, John C. Lawrence, Kohnert K-D., Agardh C-D., A Berghold, L Kristensen, Grant Sfa., N Gursoy, Leif Groop, N Freemantle, Anja Schweizer, L Pala, Legros J-J., C. Di Pietro, N. Yamamoto, J Magyar, B Nikolovski, H Ikeda, D Lee, Bruce A. Buckingham, A O Wollitzer, I Kennedy, C Ernest, Neville H. McClenaghan, S Tanaka, Asimina Mitrakou, T Heinze, W Kerner, Moeenaldeen Al-Sayed, Charles Thivolet, L Klaff, A Miconi, Cristina Valeri, J. O. Christensen, K. Ekberg, A Jardine, T Endo, X Zhang, D F Child, A Kienitz, D K Seidel, H. Tada, Sylvie Abouna, Cyrus Cooper, Catherine R Chittleborough, Roberta Assaloni, S Corbi, A K Bose, K Ozawa, C Ahn, K A Deans, G Jackowski, Martin Gibson, Patrick McElduff, O A Mojiminiyi, Manuel Serrano-Ríos, O Dupuy, A L Davydov, Iwar Klimes, Sten-Anders Ivarsson, N Ichino, R Matsutomo, E R Smith, A Stefanovska, B Dehmel, K Koniavitou, E Agascioglu, M Hatazaki, J. M. Gibson, T Yada, P Ribaux, M Rupnik, K Fridell, G Scutaru, L Chugunova, Henrietta Mulnier, A Kendereski, H Lehnert, C Billi, M Sobczak, Francisco M-Mj., L K Archibald, S Sukumvanich, David B. Dunger, I. Benke, G Yillar, N Stingemore, J. M. Boavida, Y Shi, Jimmy D. Bell, L Bozzetto, Andrew J. Ahmann, E Jebens, J Keiding, Elena Henkel, Mark Fineman, J F McRae, Carol Forsblom, S Martemucci, Lourdes Ibáñez, P G Prieto, L Ringholm Nielsen, S Pratas, B von Stritzky, Julio Rosenstock, Lee K-W., J Stocks, L J Strow, I Samarguliani, L Wennekes, R Cheung, Abhishek Nag, Roberto Gambino, Y Suleymanoglu, E Murphy, T T Durck, M F Peyrot, Y Unno, Alexander Mayorov, Eleuterio Ferrannini, D. C. Rao, D Neely, H Karunajeewa, J Palmisano, Julia B. Lewis, M Ravid, G Pons, E Junca, P Vexiau, S Sailesh, D K Miloslavskiy, O N Bondarenko, U Smith, S Torri, Constantine Tsigos, Cesario Bianchi, Mattia Locatelli, D Jaquet, Virpi Lindi, M Moroi, M E Tushuizen, P Pelicci, R Scognamiglio, Pal Pacher, S M Thyssen, A Péterfalvi, Y Ho, S Guntram, L Romics, T Nakagami, Clive S. Cockram, Irina Kowalska, K Brodbeck, Gojka Roglic, J. Dörig, Lise Tarnow, Therese Tillin, A López-Alba, Martin Krššák, Moses Elisaf, S Hata, D P Snoeck, D Schmoll, O V Udovichenko, A Scaramuzza, J Paul, John H. Fuller, Nicholas Katsilambros, Michele Muggeo, Pia Ekbom, Piero Marchetti, V Melki, C Bailleau, H Stavrianos, A D'Errico, Geremia B. Bolli, Amabile Maier, Kelter A-R., Anders Green, Q J Morélis, Steffen Thiel, C Watkins, R C Cheung, A Clark, Elvira Fioriti, N Ari, Nam J-Y., Y Cottin, L G Krinelke, H Al Mohammedi, Simon C. Fleming, C Jones, Z Kerényi, Ahn Y-H., Meile M-J., P Nánási, M Graner, V Canonico, Gangnerau M-N., Hugh R. Taylor, Giovanni Sartore, A. Dejgaard, Carol Kelley, S. Ali, Stéphane Dalle, Jeffrey S. Gonzalez, Elena Šeböková, Alexander Beck, Ingo B. Leibiger, M Rosu, C Pencea, Werner Waldhäusl, Kaltenbacher M-C., R Butzer, S Thore, Adam G. Tabak, Angelo Avogaro, E Standi, Boris Kovatchev, O Bradescu, Patrizia Dentelli, A Fujita, C Verri, R Chlup, Prasad Ydm., S V Hörsten, van der Merwe M-T., D Hilliard, W Klein, D Worthley, M Udvardy, Berit R. Jensen, A D'Avanzo, J Monaghan, K P Yeo, Guivarch P-H., B Bauduceau, D Weghuber, P Tatti, J Ybarra, S Gwozdziewiczová, E Gasparini, B Saltin, Charlotte Granhall, Howard Leventhal, R Marin, M Tumiati, Cicero Afg., L Csémy, B Berger, S Mikros, D Dall'Asta, M Shahmanesh, Y G Vasiljev, F Potthoff, H S Randeva, G De Berardis, J O Logan, K Warncke, P Uitterlinden, E Rehring, K Gilmore, K Shankhdhar, V V Bojko, M Vahatalo, E A Korolyova, D Wiemann, P G Lankisch, D Hendrie, F Galtier, M Rybarczyk, Gisela Dahlquist, N N Rudovich, G Stein, A Liebl, F Tan, A Westerlund, S Gronemann, I Franklin, Jonathan A. Prince, Peter Arner, E Skliros, T. Sparre, M Vigas, Maddalena Trombetta, L. Bjerre Knudsen, A C Sima, I Dubroca, Alastair Gray, I Weets, R Ferraresi, Schauer Ujw., E. Leinonen, S Corazza, Jonathan Levy, P K Prakash, R Guzder, S. Barnhill, John Blangero, J Herreros, G. de Vries, Cheng Ptw., A Macías-Batista, K. Capito, R Thomas, G Thomas, G Boemi, Lotte Pietraszek, Pierre Fontaine, I Holme, J Smedegaard, C A Harrop, U Helwig, B Levy, A P Gribben, Hiroto Furuta, P Beckett, S Giannini, Ruth L. Coleman, Eva Fernqvist-Forbes, N Cugnardey, A Dumas, Jane Pinaire, S E Hofer, D Shimono, Erik H. Serné, Alain D. Baron, C Battista, M Tanen, M Klementova, V Adams, J Komorowski, Antonio Nicolucci, E. C. Burns, H Sydall, M G Fanara, M G Giovannitti, N Okabayashi, Magdalena Szurkowska, I A Eroshkin, M. I. J. Uusitupa, D Ma, C C Dieguez, J Sutcliffe-Goulden, A V Gaddi, Michał Arabski, Serge Halimi, Wendy C. Burns, S Seclén, H Sugano, A Vinterby, K Backx, L F Diaconu, Fernando Gomez-Peralta, O'Harte Fpm., G Lepeniotis, D Laune, H Kvasničková, N H Wallén, G Boner, G Cieślik, Robert Hermann, Paul Q. Thomas, Y Kumon, Maria Maiello, M Atkins, Kenneth A. Earle, Guowang Xu, H Y Bae, I Reynisdottir, D Perez, D E Cannon, P Fabietti, I Geronooz, J Østergaard, K J Jeitler, S Skourtis, A Zambanini, A Saemann, K Kuboki, Helen L. Lutgers, A C Thai, Arne Melander, D Pinkowski, S G Straub, S A Wolfe-Coote, A Totora, Hayley Dickinson, A Lindenmair, A Ginis, I Faturos, F Van Eylen, C Huard, F Fu, N Wang, B M Rasmussen, Angela Napoli, L Granato, Markus M. Lerch, M. Frandsen, A Lyras, Lawrence S. Phillips, J Mabley, R Goldschmeding, B K Kilhovd, W Liu, Greg Poffenberger, P Cipriano, Anna Maria Charlotte K Lindqvist, A Matsuzawa, J Wang, T Yu, M S Pepper, Lena M. Thorn, Y Sakamoto, Blanche Schwappach, Anna L. Gloyn, P Dupraz, A. M. Schmidt, M Psallas, V Tsirimbis, Carl D. Langefeld, D Sass, H E Scholtz, M. Cailleau, Lauren Julia Brown, K Phillips, M. Iezzi, C Jayawarna, Eleni Anastasiou, R Lobmann, R Lundershausen, H Fujiwara, H R Nan, I C Smith, I A Karpova, A Navazio, S Kang, T. Hansen, T Watanabe, Gang Hu, Malik Rja., T Kennedy-Martin, Ulla M Smidt, J.M. Dekker, A A Fisher, H Liu, R E Pratley, B Sun, C Fledelius, J F Raposo, R Langham, Ahn S-Y., B R Waterhouse, Shaoping Deng, W Ricart, S V Melnichenko, Henrike Sell, M. Tomalino, N Takeda, Paola Massucco, A Harlan, W Henrich, C D Byrne, R Junik, Khalid Hussain, D Pop Gorceva, Torben Hansen, C Ritterath, K Ogawa, D V Phan, Bradley S Metcalf, Robb E. Moses, Juan P. Frias, Hitoshi Ishii, C Brisard, P Wolkow, H H Maurer, Ingo Rustenbeck, Juris J. Meier, Octavian Savu, S D Lin, V B Bregovski, A Fox, S Cicala, M. Koenen, L Vignati, O de Divitiis, Constantin Ionescu-Tirgoviste, Kilian Rittig, J Song, Riccardo Candido, F Cohen-Boulakia, U Shankhdhar, P Jahan, Antonio Tiengo, E Liepinsh, C Álvarez, Sigurd Lenzen, James E. Foley, A. del Arco, M A Maitan, U Mollenhauer, M A Na, A Beha, B Aicher, Gabriele Meyer, E Sommariva, J Åman, B Gmeinhart, Theede A-M., Bjorn Bolinder, Giulio Ceolotto, S Sbrana, F Biarnes, Damini Dey, Barbara Thorand, H H Klein, Juliana C.N. Chan, L Piconi, S Gudbjornsdottir, E Bobbioni-Harsch, Joanna Polanska, Cristian Serafinceanu, S Gambardella, Olivier Huber, J D Brunzell, T Nagasawa, Loretta Vileikyte, A Szocs, H Löwel, Z Lin, Anders Juul, H Tsuneki, L Sauriol, G Siebert, Marit E. Jørgensen, K Matthies, Brian D. Green, P Jurowski, Z Gao, M Furuya, Silvia Manfrini, Efthymios Motakis, E Souvatzoglou, Qian Y-Z., Byun S-H., T Nguyen, M R Anwar, Geltrude Mingrone, B. Idzior-Walus, Mamas A. Mamas, G Scholl-Schilling, C Bittner, A E Raptis, L Laghi, Murray Stewart, M Orel, Janet M. Bryson, Chris P Gale, Åke Lernmark, A B Escorza-Domínguez, C Fuentes, A S Einarsdottir, M O Akinsola, P Maisonneuve, K S Leong, B Missler, Simona Frontoni, Con Tsalamandris, Flavio Francini, D Rouiller, B.E. de Galan, Girolama Alessandra Marfia, M Fioravanti, A E Weber, M Nargis, P Nowacki, Y Chen, B Larsen, Ruth E. Gimeno, A Wojciechowska Luźniak, R Meisterfeld, Limei Liu, A Ohashi, T Pieber, Bin Yao, G A Herman, M Pallini, R E Honkanen, H Nyblom, R Humbrecht, Takashi Tsuboi, Pinar Topsever, Monika Kellerer, J Woods, Steen Stender, C Kapitza, Sherwyn Schwartz, M Taskiran, N Hashimoto, A Jabin Gustafsson, K C Silva, I Nitz, S Dzienis-Straczkowska, H Elouil, L Sommese, Patricia A. McKinney, S Ogawa, E Carr, I Porchay, Robyn G Langham, Bruno Vergès, K H Usadel, S Sivakumaran, H M Hearnshaw, José Luis Santos, R Ishibashi, F Huq, Lebrethon M-C., Z Leshchenko, Elisabetta Torlone, A Saltiki, A Plaschke, Wolfgang Koenig, D. D'Avola, C L McTernan, Haruhiko Osawa, G Cazzetta, S J Lee, S Al Jebely, Hoogma Rpl., A Shimizu, Tack Cjj., Itamar Raz, Adrian Vella, P. B. M. de Andrade, Aguiar Lgk., Wolfgang E. Schmidt, T Wolthers, W. Gatling, T S Purewal, Philipp E. Scherer, E Heller, Stephan Gielen, Jo S-R., Monica Vedovato, L Nosek, R Ryder, G Giassakis, A Cretti, A Wajngot, T Waldhör, S Zoric, H C Lee, L Pulkkinen, L Lacey, I Tomescu, R S Patarrao, X C Liu, Lauge Schäffer, Jarkko Ustinov, Anders Thorell, K Kangawa, P J Wood, T Yeoh, Jo Satoh, G Psaras, Volker Burkart, Karin Schindler, Dario Pitocco, M Kolopp, Gabriela Roman, E Renström, M Goldberg, M Beregszaszi, S Senkel, M F Meyer, María Luisa Villanueva-Peñacarrillo, Elena Beltramo, J E Snaar, A Hayward, C Abreu-Padí, S E Vielwerth, R Krones, C C Stanciu, M Izquierdo, I Elbing, R Astorga, V I Bouloukos, P Zabielski, S Precerutti, Kang S-Y., K L Pratt, Joost H-G., Matthew L. Iorio, Naomi S. Levitt, Yutaka Seino, Peter A. Gottlieb, I Ehrén, Y Matsuyama, Jean Claude Mbanya, S Parveen, R Purvis, A Cappadona, V V Afanasyeva, K Löbner, S Del Guerra, V Valle, Victor A. Gault, M Tan, M M Budge, I Ioannidis, M Ishizawa, Castelli, D Nowak, János Rigó, Claudia Bleck, E Degli Esposti, C Tortul, M Klebach, E Schvarcz, L Pauline, D Krusova, J Csillag, Park K-G., Kaichi Kida, P Bialasiewicz, S Seeliger, B A Williams, P Mistry, T Nicer, N Ahmed, H Ohashi, Peter Achenbach, van Hessen Paw., Jesús Cancelas, E Cizmarova, D Takahashi, K Tanaka, A M Rojo Llobet, Q Chen, A J Garber, P Halban, B Brunmair, A Barthel, M R Katdare, Dominique Laude, M E Pavkov, C Leach, C M Breschi, S Okada, B Balent, Ornella Massa, Ravi K. Garg, van Loon Ljc., K Obuobie, W Moll, L Varanese, V Smejkalova, B Royer, M Roth, M Belfiglio, Chae M-K., I Kimura, Casper G. Schalkwijk, Hans-Jürgen Hedrich, Heinsbroek Acm., Jared Rutter, Ken Williams, K O Lee, A N Symeonidis, J B Brown, M Pfeuffer, W. C. Knowler, A N Barsukov, A Woods, T W Kim, Khalid Bak., Andrea Mari, David J. Pettitt, Y Tomioka, J Hochman, Mireia Mora Porta, K Pagava, Krzysztof C. Lewandowski, J Taton, T Yasaka, M Tyrberg, M Sargin, P Szenthe, R Sicree, C Abreu-Padín, Magdalena Lundgren, J Radziuk, Eili Tranheim Kase, W L Goudzwaard, Yanbing Li, E Ramos, H Monastiriotis, J Cur, S Pu, Lakka H-M., Park J-S., Fabrizio Barbetti, S. Ciani, Pavel Flachs, N C Correia, Angela A. Rivellese, F Ebara, Nicolas Musi, H van Ahlen, Helen M. Colhoun, Anna Czech, Steen B. Pedersen, N Jost, N Da Silva, J Nóvoa, Y Onuma, Anna Körner, D Michael, M Straczkowski, I. Truyen, R. Schmid, Søren Paaske Johnsen, H Koenig, B. Miranda-Palma, E Wasén, F Pervin, P Cavallo-Perin, M Niessen, E P Shavrikova, P Tarkun, M Vavlukis, H Gang, O Sánchez-Vilar, C Dalla Man, S. M. Haffner, R Eggertsen, L Pucci, F T Fiedorek, E I Mainas, H Holdass, Peter R. Shepherd, A Banu, R Lichiardopol, Lee M-K., N Zaytseva, B Gumbiner, Strotmann H-J., L Y Baranova, A Kissebah, A Pezzatini, I Kharroubi, N A Thornberry, A J Buckley, B Pontiggia, T Chen, M Ikebukuro, J Leach, C Frost, J Han, H Hashizume, G Poulsen, H Eckert, Paul Zimmet, Lee J-H., Peter E. Heding, S A Ross, Nils J. Færgeman, Giuseppe Penno, T Varbanova, H S Shon, Z Canturk, S Akahane, Noel G. Morgan, A Sener, Seronde M-E., P K Thaware, W Insull, S Forst, K E White, Christoffer Hedetoft, M R Holland, K Okamoto, F Yamagata, Markus Lassila, N Tanaka, Kristian Midthjell, R Isoaho, D A Legemate, M Motzkau, Y H Kang, A P Nescheret, J Boiko, Hemmo A. Drexhage, Gagik R Galstyan, Naim Shehadeh, Henning Beck-Nielsen, T I Justesen, O Kalter-Leibovici, T Vahlberg, M Mozdzan, G Siegert, V Dumenil, Katsumi Eguchi, J A Vazquez, Sally Hollis, H Haberland, A Souvatzoglou, M L Gavete, K. S. Nair, Katharine R. Owen, C Garcia-Rodenas, Gerald I. Shulman, Peters, H A Parkes, Y S Kim, Mats Rönnback, Isabelle Leclerc, Marie-Hélène Giroix, I D Caterson, S G Rønn, L Scionti, Silvia Pinach, Hans Christian Reinecker, Kathryn Noyes, P McTernan, C Y Tan, N. Lalic, Richard D. Carr, M. Toman, D Papazoglou, Domenico Bosco, G Lübben, F. Costanza, Tania Maffucci, Jonas Nygren, Ole Lander Svendsen, Kristin Taylor, Ugo Boggi, A Kayserilioglu, Gudmar Thorleifsson, G J Dunseath, B. Balkau, T Zieher, M Schwarts, A. R. Cobitz, P de Pablos, I Recas, Carlos Lorenzo, Pamela J. Shaw, Y Cho, C Münscher, Anna Maestroni, Milan Zdravkovic, Gerstl E-M., L L Xiu, Yoshitaka Kajimoto, A Deb, F Osaki, G Kirilov, B Staffler, Běla Bendlová, M Rebelatto, Frank Reimann, B Ø Christoffersen, S Durant, Fruchart J-C., Ravinder J. Singh, V Connolly, Q Zhang, Alexandra Kautzky-Willer, Francesco Andreozzi, N Talai Rad, V Loyková, Trampisch H-J., Stefano Menini, F. Rodríguez de Fonseca, W Hanif, H J Böhles, S Fotiadis, Philippe André, T Kubiak, T Friede, J Murin, Erwin Schleicher, Adam Garrow, M Takahashi, P Valensi, S Pappas, E Lim, D N Staroverova, C Tadgell, C Dessapt, Brittany A. Rasmussen, L Cheung, L E Porter, R Ishihara, J Ravisy, T Inukai, Christine Winzer, E M Özer, Nish Chaturvedi, Ana Chico, Ville-Petteri Mäkinen, N Bellili, Howlader, Jansson P-A., A Martella, Jan Frystyk, T Kakko, K Hershon, S Hoashi, B Nag, C Chabrolle, B Leatherdale, J. Lu, Stephen Colagiuri, C Brendel, Michael Roden, Peter Clausen, A L Macdonald, R A DeFronzo, F A VanNieuwenhoven, Sirkka Keinänen-Kiukaanniemi, Jonas J-C., Hobbs Fdr., H Uchino, S Del Prato, E Polakowska, L Shankhdhar, Hedrich H-J., S Rodriguez-Cuenca, A Schwarzmaier-D'Assie, K Fukuda, Robert H. Eckel, A. Hilding, A Rutscher, D Kerr, Junhua Li, C. Köhler, A Banaszak, Peter Lönnroth, P Wulff, M A Gruzov, Fariba Shojaee-Moradie, S Matsumoto, J P New, N Barthes, M G Leyck Dieken, Mian Li, O Ivanova, G Papalia, K A Nilsson, Parving H-H., P Merz, M. A. Schweitzer, A Morris, P. Andersen, O Tschritter, M Fitch, V Fejfarova, Elisabeth Bernroider, E C Kiawi, M de Kerdanet, Claus B. Juhl, C Taxvig, Kerstin Berntorp, Birgitte Andersen, C Coscelli, C Ktori, Norio Abiru, R Mössner, Hiroko Hirooka, Jens J. Holst, Q Dan, H F Gu, C Gimpelewicz, A Oeckinghaus, B DelBuono, J Kuroda, P Kastner, Clemens Fürnsinn, H Usui, R Mosqueda-Garcia, P De Meyts, K Yamagami, M Tóth, V Leite, H Alberti, M Meneses, Gregory Collier, E G Starostina, C Delaporte, Agostino Consoli, François Alhenc-Gelas, S Tonstad, G Schuler, J Juszczyk, G Hoefle, M Wilken, Mark A. Yorek, Volker Lodwig, G Edwards, E Catellani, Ewa Wender-Ozegowska, Kurt Hoffmann, I Markova, Steven J. Hunter, A Venkataraman, Bente Klarlund Pedersen, A Kengne, Ken K. Ong, L A Calo, M Huckova, Y Morikawa, Pierina Richiusa, D Giuffrida, Sonia Brichard, Giuseppe Paolisso, Andrew T. Hattersley, M Vankova, Jon G. Mabley, G Salvidio, M Montolio, X Yang, Barbara N. Campaigne, Ralph R. Turner, Andrew J.M. Boulton, P Johnston, S Berchtold, Roger Corder, D Ledwig, M. Di Mauro, Houweling, J H Bowker, J Hilsted, Shin D-W., B Kiran, E Esteve, A J Cameron, S Spera, Kathrin Maedler, S Tsujii, J. H. DeVries, S Cailleaux, M Walter, A Florén, R Lehtonen, Davis Tme., N Patsourakos, J. Marco, G Lepore, L Morcillo, J Burén, Paul Smits, Juraj Koska, Chung J-H., Katherine S. Elliott, Bong Soo Cha, Christian Weyer, F Montorsi, L G Søndergaard, H Horie, M Herten, N Aghamohamadzadeh, L A Scrocchi, A Oyarzún, Rutten Geh., K Yamada, M Zivkovic, R S Beifort, Lee I-K., S D Bouman, H Böhles, Dwight E. Matthews, Orville G. Kolterman, Bidda Rolin, I Shymanskyy, P Thomakos, John Strand, A Virkamäki, C M Clark, Y Tokumasa, Odusanya Pot., Joel F. Habener, Abel López-Bermejo, Anders Tengholm, D Argon, Lajoix A-D., N Aki, L Kessler, N Takahashi, A Zmysłowska, Kåre I. Birkeland, D Soon, Lars Køber, M Vaňková, Lee W-C., F Payeras-Más, C Lau, E Ramos Lopez, L Lukic, A Suehiro, Stephan J-A., I Estalella, Jørgen Jensen, Liaqat Ali, V S Dimitrijevic Sreckovic, V P Maximova, G Salietti, M Ding, Yuksel Altuntas, Chung K-D., F Kaufman, Ludwig Wagner, C Calvi, D X Gram, David G. Bruce, K Sprenger, M Schweers, D Kush, D B Panagiotakos, J. M. Currie, Luis Castaño, Dag E. Undlien, D. Haspel, A Suzuki, J Cederholm, S Garcia, L Cynober, P O'Hare, A Tsur, Christine Zimmermann, M Faimalie, V V Poltorak, S Alba, Axel Haupt, J Varga, Tetsuya Yamada, M Shoji, R H Lloyd-Mostyn, Péter Pusztai, Doney Asf., M N Gangnerau, I Shimizu, Henrik Ortsäter, F Liska, Mandeep Bajaj, H Sarui, Michal Andel, S Chiheb, Diane Barker, A. van Tol, Brigitte Reusens, I Anafaroglu, Giel Nijpels, F Bongardt, K Taxildaris, M. Orsini Federici, V A Horton, K Ota, A McCall, M Vladica, Anita M. Hennige, Karsten Müssig, A Philotheou, I Chronopoulos, N A Perrin, B Janand-Delenne, Søren S Lund, S Duarte, R Bernardi, R Holman, Safia Costes, Hubert Kolb, G J Schlömer, Rainer Lehmann, Lusson J-R., J K Malone, X I Nkomo, Lars Melholt Rasmussen, E G Chittilapilly, J Satrústegui, A M Abbatecola, M Cristini, U Hanson, María Teresa Martínez-Larrad, Frida Renström, Luigi Uccioli, A Hennige, T Akhobadze, U Raval, D J McCarty, Didac Mauricio, S Horiuchi, V V Nosikov, B Wierusz-Wysocka, K Xiang, H L Fehm, Elaine Gutierrez, S Salman, E Siekierka-Kleiser, P Martul, N Kajaia, A W Herling, Tony R. Merriman, Kirsten J. Ward, René Gross, S K Althouse, S Woodhead, Emmanuel Cosson, T Rönnemaa, T M Filiz, Jerzy Loba, S Sha, Klas Malmberg, Carlo Pesce, Jung D-S., I Majdrakova, Thomas Forst, M Schütt, Hierl F-X., A M Efanov, I Verschraegen, H B Jensen-Holm, D Deckhut, Frida Leonetti, N Selzle, G Cassetti, Jose L Mesa, G Morrison, Christian-Heinz Anderwald, C Kliebe-Frisch, J H Moffitt, P Lahm, Hiroshi Ishiguro, E. Borgo, A Keech, L Quagliaro, Thomas O. Ola, Henquin J-C., W J Sluiter, F Leprêtre, Kalliopi Kotsa, Peter Karl Jacobsen, E Sanchez-Largo, E Gaia, Daniel R. Witte, Sidsel Graff-Iversen, G Seebohm, E Cacès, R G Khalifah, W Wilson, Avan Aihie Sayer, C Raffaitin, J Gumprecht, T Lehmann, E Migliaccio, R Urrutia, E Shelestova, A V Chervonsky, Stefan Mustafa, Y Hisano, Erik A. Richter, J Miettinen, K M Gottesdiener, Gangyi Yang, D Chevenne, A Girach, P Samuelsson, Taskinen M-R., D Ciociaro, D Aydemir, Yang S-B., P De, Dongliang Zhuang, Nathan R. Hill, B V Hansen, Hideki Katagiri, M Saryusz-Wolska, G Y Gandhi, Nicholas Witt, D Berzi, B J Mejía-Pedraza, D G Burrin, R Mather, V Ashkenazi-Katalan, Y Yamasaki, G B Jensen, Emma L. Edghill, Y Wang, I J Deary, M Langenfeld, J L James, K Yozai, T Appleton, Jamal A-M., A. Di Benedetto, Yutaka Nakaya, Elin Rebecka Carlsson, Y Park, T Carpenter, Attila Bokor, Patrick Harriott, S Ait El Mkadem, B Lormeau, A Ceylan-Isık, Stefania Bandinelli, Isabel Valverde, N Brevnova, Pietro Passera, F Escrivá, J El-Din, G Ertl, Tringham, S Wakabayashi, J Soler-Soler, T Tenenbaum, Kurt Widhalm, S Yoshizumi, M Masin, L Tsibina, S Shutler, Kirsten Ohm Kyvik, Nigel J. Crowther, M C O'Neill, A N Pehlivanidis, A Kürklü, P Bouter, Savontaus M-L., Sharp Gwg., Kivelä S-L., A Krasner, E Carrasco, Ravi V. Shah, A Skytthe, P Roca, B O Boehm, Felicia Ranta, Ulrich Werner, A Shearer, D Hosaka, P Papadimitriou, C Dimosthenopoulos, L Farkas, K Short, S Futakuchi, Z Garamvölgyi, C Hohberg, B Heckmann, M S Fineman, H Akahori, Yasuhiko Iwamoto, K Hashimoto, Zhihui Zhong, S Shubeska Stratrova, G M Cvijovic, C Neumann-Haefelin, Amna Khamis, J D Betteridge, P Fratino, Itxaso Rica, L Tsutskiridze, S Nakajima, S N Koval, Paolo Brunetti, J Buithieu, A K Rasmussen, John P. New, V W Rahlfs, S Pellitero, Claude Bouchard, P D van Poelje, A Ghio, S Barcelo-Batllori, B Götz, Fernando Djs., Antonio E. Pontiroli, P Lim, M Eckhard, Norbert Stefan, L Alviggi, G A Thomson, S Bergmann, E De Amici, Elisa Pagnin, C Gatsiou, Markku Laakso, M. Massi Benedetti, Szabo, E R Trimble, H Konya, T Örn, G Valsamakis, J Zhang, S Mcintyre, H Yu, C Huang, Ken’ya Sakamoto, David A. Savage, Martin Whyte, S Vakkalanka, G C Webb, R. Reitano, D James, D Bradshaw, K G Parhofer, Napoleone Ferrara, P Boucek, Henry J. Dargie, V Artikis, R A Flett, Giovanni Anfossi, I S Simeonov, D J Drucker, A Chamson, Phillips Diw., Charlotte Malis, Bernd Schultes, M. I. Hawa, Shanta J. Persaud, S Geloneze, J Sponarova, S. Lahdenperä, Y Komatsu, B Capaldo, Wojciech Młynarski, D Brasacchio, G Allochis, H Takeda, W Doering, J Grimshaw, Ichiro Niki, D Degiannis, C Köder, Carla Iacobini, Norbert Hermanns, Voss, A Grimaldi, R. Wassmuth, L Bernardi, A. Crinò, T S Temelkova-Kurktschiev, C Nita, Michail Antsiferov, A Balini, Yoo H-J., Giovanna Oddi, A C Bossi, D. S. Harry, Á Vatay, Peter R. Flatt, M Fukumoto, Sebastio Perrini, Halfoun Vlc., R Helal, Donald C. Simonson, B L Shine, E Maltezos, J Ryskjær, H Bessho, Yoichiro Kamatani, M Veitenhansl, M Farnier, N Hole, M Abbasi, Cha B-Y., Gall M-A., M Bogatean, Amitha Gopinath, M Vettore, O Seda, V J Willey, Carl Johan Östgren, R M Parhimovich, Rennings Ajm., B G Kravitz, D Lipkin, Andrea Galgani, A Nakajima, Alvin C. Powers, J E Paiker, E Souhami, Per Hildebrandt, Charlotte Kragelund, C Lindloh, M Sasaki, Torben F. Ørntoft, Nilima Biswas, G Giani, J Lazarus, H U Janka, H Li, F Reeß, S Athanaselis, S Sankar, Carlos Hernández, A Tone, R Capani, E Biermann, C. N. Hales, Petersen Jla., M Federici, Torben Jørgensen, P Kurtzhals, Michael N. Weedon, Eva Lind Rasmussen, Rupert Beale, B Leiting, Per K. Christensen, R J Young, M J Wooddell, Guy P. Nason, Jean-François Martin, J A Ruggles, C De Natale, Renu A. Kowluru, Alexandra Schneider, M E Cerf, S Galande, V. Miselli, Romano Regazzi, I Gkioulmpasanis, D Voinovich, Susanne Ullrich, Zhao P-L., R Rabasa, W G Towers, D Cerrato, G A Nuttall, Halimi J-M., Marco Falasca, Antonio Zorzano, D Bottino, C J Mullany, Michael Alvarsson, Matthias Nauck, E Pankowska, S Bulgurlu, U Hoss, Eiji Kawasaki, Davide Lauro, Ha Kbn., Beauvieux M-C., Enzo Bonora, J Lane, H Mahtab, N. Klöting, D L Winter, Freyse E-J., G. Biemer-Daub, Cecilia Invitti, J Dabrowski, Laurence Ladrière, Catherine Born, A Hiukka, Y Inoue, M Cimmino, Y K Kim, Jeanette Kuhl, J Peiker, J Szánthó, B. Zierhut, P Blazicek, M Calbacho, L Marenah, M Zbinden, Y Nakasone, David R. Owens, P Ross, T Vilsbøll, A Šmahelová, E Boldrini, S Santos-Palacios, T Krarup, J Bonnet, Dorte Vistisen, R A Ritzel, Tsuguhito Ota, L Guja, B Chappuis, Nils Billestrup, A Grilli, Polly J. Bingley, Sabine Fischer, Kenneth Robertson, P M Bell, R Coll, Y Uchigata, A Glebocka, L Rizzo, Swangjit Suraamornkul, Egberts E-H., E Zapanti, K Oi, Hideichi Makino, N. Visalli, Häkkinen A-M., Uwe Voelker, Ian Lawrence, Marju Orho-Melander, Mary-Elizabeth Patti, K Herrmann, B Hultberg, Hoekstra Jbl., Nael Shaat, Hannele Yki-Järvinen, E Canbek, E Madarász, A Marsocci, N A Foxwell, P Sorichetti, Eva Aguilera, A Bronisz, J LaSalle, M Freeman, M S Kipnes, K Ažman-Juvan, Stefan R. Bornstein, Y Kainou, Francesca Porcellati, Bart Keymeulen, Y Takemura, Joanne Rasschaert, L Juurinen, M Broch, Paddison Cam., Jens Faber, M Sanges, R Swift, S D Luzio, T Kuchmerovska, J. De Schepper, Sabina Baumgartner-Parzer, C. Herder, Peter Rossing, C L Frost, K Kaku, Zhiguang Zhou, Thomas C. Wascher, Song B-R., S Bai, M Vázquez, B. Van der Auwera, A Pavanini, Luisa Gilardini, K S Sunnerhagen, Claes B. Wollheim, S Shinn, Christian Dina, Yoichiro Iwakura, L Thomas, K C Lasseter, J Crook, V Kraft, C. J. Bailey, E Estimes, A Jiménez, Georgeanna J. Klingensmith, G Menzinger, C Rinsch, Anna Jonsson, Masakazu Kobayashi, A Goertz, K Papatheodorou, J. Lopes de Faria, C Karasu-Yilmaz, C H Hobbs, J Behjati, R Buckingham, A Patruno, A Heinrich, L. Kalbe, A Oglesby, Y Fujita, O Zacharopoulou, P Di Fulvio, G Poggi, J Jowett, W Isley, Susumu Suzuki, M Zamaklar, A M Carter, S. Efendic, Claude Knauf, Stephen B. Williams, Wu H-S., S de Kreutzenberg, Susanne Schwenke, A Coppelli, S Maxeiner, E Stridde, M Zurawska, J. H. Fuller, P Di Tomo, D Pisarczyk-Wiza, J Dudenhausen, Robert G. Nelson, Catherine Pihoker, M F Bullano, Tuomo Rankinen, J Wada, R A Greiner, L A Tchugunova, T Okada, M Bosevski, G Dentan, S Bruce, H Rittmeier, I Peovska, B Augendre-Ferrante, Zsolt Bosnyak, H van Wasen, Peter Almgren, Lut Overbergh, Bernard R. Landau, D Schumann, Frédérique Diraison, B Dietrich, Q Zhou, Alan D. Cherrington, Ottavio Giampietro, Margaret M Band, G Brandrup-Wogsen, R Eher, N Kim, Merlin C. Thomas, V Anand, K Szosland, B Gustafson, Aina S. Lihn, Mamputu J-C., Dosch H-M., G Paragh, Robert E. Ratner, C D Kim, A Heckel, Adrian J. Bone, V G Athyros, Léopold Fezeu, M A Denke, N Karlovich, M Morgutti, N Villela, Mathias D. Brendel, Peter Krippeit-Drews, Akira Matsutani, Gyula Tamás, Ole Schmitz, Chae S-H., J T Willerson, L Galuska, A Vanoli, G Habib, Giuseppe Remuzzi, R. R. Rizza, R. Sillard, S Longhitano, Hongliang Li, Y I Karachenzev, J Denne, M Grenningloh, J Hayes, B J Goldstein, S Erdmann, A Midtgaard, D F Giannakopoulou, Dick de Zeeuw, A. Holstein, J Brązert, M Zmudzinska, R E Davis, Felipe F. Casanueva, F Huet, Stephanie A. Amiel, Y Miyake, N Hiroi, Eberhard Standl, G Sebag, Caroline Kistorp, R Jaziri, Rita Basu, M Mertl-Roetzer, Flavia Franconi, U. Di Mario, M Brammer, U Langel, Meghan L. Marré, F Garcia, G H Thoresen, Ingrid Kockum, H Gin, L Sedova, Susanne Rudberg, Martin Prázný, Diana Rubin, I Kyrou, T. J. Wilkin, A D Kriketos, E M Egido, K. Sugimoto, Janssen Pgh., E Aktas, E Rylander, M Ramazashvili, Hans-Ulrich Häring, Mackay Djg., J Skupien, Yoshihisa Nakatani, I Karádi, Jurg Ott, H Makki, A J Ló, T B Bödvarsdóttir, Timo A. Lakka, J Nerup, Anders Rasmussen Rinnov, F Assimacopoulos-Jeannet, G Beretta Anguissola, F U Rodriguez, A Garcia-España, B Neve, P Curtis, M Boldrin, E Csongradi, M E Hossain, Jürgen Kasper, Concetta Suraci, Lex M. Bouter, Z Skrivanek, H Bischoff, H Yamazaki, Nicola Jackson, Irene M Stratton, D Vogelsang, E Baranyi, Andrei I. Oprescu, X Yan, L A Resnik, A Wajman, M J Sheetz, R T Ribeiro, K Oono, Angelika Thon, A H Boss, K U Wittrup-Jensen, Nanne Kleefstra, E. Ferrari, Thomas Strack, Häring H-U., R Chow, Gabriele Perriello, R Z Timar, R Giannarelli, Y Saito, Thomas Mandrup-Poulsen, Peter Bergsten, D Raunig, A Rovira, Gunnar Sigurdsson, Z Melczer, L Gu, R Elli, C Chan, F N Wang, Carmine G. Fanelli, Thomas Illig, M Szabó, K Holtz-Neiderer, R Kominato, Nieves González, M Pfohl, D. P. Bataille, R Peter, Robert J. Heine, E Bacillo, S J Creely, D Bruttomesso, D Karagianni, I O Shymanskyy, Lüddeke H-J., D P Kurktschiev, H J Kim, K Nanjo, B R Lee, Valeriya Lyssenko, Y Hasegawa, P Langer, C Gemma, Martin E. Fernandez-Zapico, Dale S. Edgerton, C Romano, Sotirios A. Raptis, S Ishida, S Frantz, U Ott, D Simmons, Philippe Morel, P M George, E Müller, F Saleh, M. Grabert, John A. Todd, V Golozoubova, M Sikter, Carla Giordano, P K Awah, M Colding-Jorgensen, O Schoeffski, T Suda, A V Kulikovskaya, T. Lauritzen, Y Fujii, Philip G. McTernan, G V Donchenko, D P Hancock, G Renier, G Maclaine, Nita G. Forouhi, O Kolterman, S Nag, Bengt Vessby, J Genescà, D Moruzzo, P Dittrich, Aristidis Veves, M Sacco, Christopher Shaw, F Agrò, F Oana, I I Dedov, P Sergeev, A Sotiropoulos, L Moretti, Paolo Pinton, Nigel P. Jones, K Takemoto, Mary A. Cotter, Mauro Castellarin, N Roper, Peter Gæde, E Cerasi, T Hoffmann, D Gabellini, Ramzi A. Ajjan, Y Yu, Huh K-B., G I Kuntchevich, Kenichi Shikata, U Puch, Hirofumi Misu, P García, J Shen, S M Katzman, Marco Castagneto, H H Hundborg, E Kaszas, Choi M-H., R Battiato, H Shi, Y Oh, Adela Penesova, C Xipnitos, Julie C. Price, T Imamura, A M Tonkin, C Tang, A A Barros-Filho, N Chartrel, A Findlow, Z V Caparevic, Jukka Westerbacka, T Ishii, A R Vlad, O V Tuzova, M Y Gorshunska, Knut Borch-Johnsen, P Pizzocri, Bernt Lindahl, T M Wallace, H C Deng, Mikael Knip, M Shimodahira, Renato Lauro, F Zelaya, Giovanni Pacini, I Franzetti, E Karagiannis, L Wood, Wendy A. Davis, Karen J. Mcneil, M Scott, Mariella Sorcini, G Lasfargues, Philippe Froguel, Kjersti S. Rønningen, R Chotmongkol, G Zasadzinska, R Iakoubov, E Kiwanuka, M Arribas, M Schuler, K Pyörälä, H. de la Calle, Maciej Wideł, V Lowe, Ilaria Dicembrini, D H Beran, R Morikawa, K Satani, G Scarselli, Lea Bruhn Nielsen, Ahn Y-M., Aveni Haynes, Leslie Rdg., Basem M. Abdallah, K V Allen, Max Bulsara, Masataka Kusunoki, D L Duhamel, F Cipollone, Lee S-J., È Palik, A I Gladkich, T Sato, Yogish C. Kudva, L Gardete-Correia, Yoshinori Hinokio, Martin Rossmeisl, Lorena Amadio, G Gates, K Wittrup-Jensen, A Pfützner, E Tourel, V Moya-Suri, Y Imai, U Zeymer, A I Santos, J Mueller, M Lombardi, K Luz, Olga Kotova, Angela Scipioni, Bernard Portha, Reinhard G. Bretzel, Risa Ozaki, I A Katz, L Dakovska, Sampath Narayanan, T P Levchenko, M Lazarova, J Stock, D D Kim, J J Vendrell, Heikki O. Tikkanen, Ostenson C-G., Ronan Roussel, Hideaki Nakagawa, Gabriel I. Uwaifo, Paul D. Griffiths, Klaus Moeschel, Lee B-W., I Rojas, K. Staiger, Brendan T. Kinsley, J Gebel, Alessandra Bertolotto, Anthony Zagar, Domenico Accili, Richard H. Jones, A Mayorov, J M Morrell, S Soedamah-Mathu, R Obrenovic, T C Cavakcanti, J Łopatyński, Ottavia Porzio, A Barbera, R Piechatzek, Ewa Małecka-Panas, M M Mocanu, David W. Dunstan, A Y Tokmakova, Sei Hyun Baik, A De Bellis, D Kallend, D Melloul, C Rosak, S G Paule, Vicki Thallas, A Schrodter, P Roesen, G M Steil, Sabine E. Hofer, P Juretschke, D Zozulinska, Slavisa Ninkovic, V Pauvaday, D A Darko, Kim J-I., David R. Tomlinson, Fach E-M., A Papaefstathiou, L Gürtler, N Wiernsperger, J Simcox, L M Dickson, S Fujii, J Schwarz, Lars S. Rasmussen, M Trautmann, M Uzan, A Sato, Hans Günther Wahl, Tore Julsrud Berg, Kar Keung Cheng, C J Emery, M Lipsett, U Belz, Majlinda Lako, E M Gould, Rikke Due-Andersen, J N Mbanya, C Fiore, Takao Nakamura, Shield Jph., B Nadal, Lene Simonsen, Barry M. Brenner, D Fedak, J Chen, Laura E. Parton, Gao H-Y., John B. Buse, B Vialettes, M Y Guo, T Evers, Melanie J. Davies, Joan Soler, D Schmiegelt, Bárbara Angel, Hoe, B Parker, G Giovannitti, Ross Lawrenson, O Rigal, J Raastam, D S Kim, Björn Olde, Berggren P-O., Calum Sutherland, F Vittone, A Gauthey, A. M. Wagner, Paul Czernichow, Arturo Rosso, A Peter, J Hřebíček, V Martínek, B Jardin, A Fiorito, M V Trigo, S Bassan, N R Busciantella, C Turpini, G Seghieri, R Gelisio, K Nakanishi, D Pittasch, A Kamaratos, Irminger J-C., Monika Cahova, Y. Miyazaki, D V Coppini, Avierinos J-F., Erifili Hatziagelaki, S Schmauss, Richard G. Feltbower, Giancarlo Viberti, P G Steg, S Paulin, S M Marcovina, C. Marzari, Keld Fosgerau, S A Constantin, Adam Kretowski, K Yoshiuchi, K Cypryk, Geloneze, Jason L. Eriksen, Luis Garcia, L A Lavery, A Paroli, C A Ellery, M Morales de Teresa, Martin Ridderstråle, Riccardo C. Bonadonna, Solomon Tesfaye, N Gebeloglu, S Odenbach, A Baumgarten, Frank Schaper, K Dimitriou, F Costantino, O Basat, C A Mathis, V Lassmann-Vague, Kim D-J., J E Pessin, Shi Y-F., Michael Ristow, Kerstin Brismar, V Padilla, M Paganelli, Katinka Stoffels, A Caselli, R Cioni, G Nosso, C Conde, J Foley, M Tsuchiya, I Naumenkova, J M Pou, D Holmes, Richard J MacIsaac, M J Davies, G Jenkins, F Lavalle-Gonzalez, Daphne Owens, E Gibson, Richard E. Gilbert, Foster Avm., Sieradzki J, M W Davis, S Lahiry, James Mason, S Di Silvestre, Ken Walder, B Sporleder, B P Nixon, S Murao, Claus Thamer, V Kren, M A Buyukbese, B Burwinkel, M L Bigelow, C Bellin, P Mayr, J C Beer, Kim K-S., Willy Malaisse, A Ojeda, M Macugowska, A Varró, E Hammer, A R Baker, Alan W. Stitt, Rayaz A. Malik, H A Keizer, A Poscia, V Suri, K Kusterer, Allan D. Struthers, Martin J. Hessner, L A Anderson, Nigel Irwin, J S Christiansen, H V Schaff, D Hancock, L Nielsen, J J Mukherjee, M Essenpreis, C R Stephenson, D Betoulle, T Shibata, L Blonde, S O'Neil, T Hrachovinova, B Mirkiewicz-Sieradzka, G M Valorani, S Jahan, P Luzniak, Stephanie Halford, B Young, E Zabala, P Jousilahti, Hubert Vidal, P Kowey, G Hawthorne, A Zalewski, D Cokkinos, J Maroni, S Drewelow, Y Gao, Maria Paula Macedo, Wendy Dean, Janusz Blasiak, Delporte M-Ll., J Doupis, S Marcu, G Su, D Christakidis, Sabine Sewing, P Pánczél, H Matsumoto, K Rickenbach, A Calì, Giuseppe Derosa, A Linke, H Piperidou, Y Miura, B Kocher, D Nelson, Jo Y-Y., Päivi J. Miettinen, D Leontsini, M Prasek, A R Jones-Leone, H Ahn, R Alemzadeh, Yoshitomo Oka, Anna Solini, Fernanda Ortis, Neville Owen, Simona Cernea, Maciej Pawłowski, Sherry Martin, J L Selam, T Tulokas, K Lammi, Rolland J-F., Stephen Thomas, R.T. de Jongh, C Diehm, S Altimir, E. Manzato, W Szymczak, Michael Khan, S Lally, S Aycheh, I Stengele, Kim S-I., Zbigniew Szybiński, Carol Bower, Koichi Kato, I Evangelista, Eveline Eschwège, S Fujimoto, J Born, Elizabeth J. Mayer-Davis, O Schnell, Y Zhang, C Jørgensen, Lorenzo Piemonti, P Pithova, M Shirai, B. Kilhovd, M Dzabic, A.D. Hughes, Denis Raccah, P Berto, K Nizheradze, Tiinamaija Tuomi, Thomas Nyström, J A Shu, J Ostman, E Cicconetti, Helen E. Thomas, Margareta Svensson, P Vautrin, Andreas Fritsche, Lawrence Rosenberg, K Stoschitzky, M Yamakoshi, B Pandey, Kazuaki Nagashima, N Pound, W Srikusalanukul, D D Sandeman, L Wu, M C Stapperfend, P Saxena, SE Jones, C Colombo, C Caccioppoli, A K Keenan, P Piatkiewicz, H Frobøse, H-Erich Wichmann, J Marquez, C A Maloney, F Stasini, Elena Matteucci, J Arezzo, M Dalfrà, Maria Aisporna, M Nastoll, M Germán, M Riddle, Munehide Matsuhisa, Alessandro Sartorio, Henrik Toft Sørensen, Lars Rydén, I Panagiotou, M Fisher, J P Yeo, M C Riddle, K Anthony, Patrizia Ippolita Patera, T Bobkiewicz-Kozłowska, A Gasiorowska, M Artwohl, Kim K-W., Lutz Heinemann, P V Voss, A Tsuchida, N Ueda, Huriya Beyan, Joachim Rosenbauer, M Sultana, N I Gorbenko, B B Rønn, J Bělobrádková, Michael Haap, J Després, K Cooper, C Tzioras, J Goodwin, J A Myers, Eriksson A-K., M Sahilli, H Sasaki, D Grassetti, S Nencioni, Suzuki J-Y., F Wang, Erica L. Fletcher, H Chen, P Augstein, W J Valentine, Burkhard Göke, Damien Jolley, K Raun, A Seftel, K Okumura, N Follak, A Risse, M Stolinski, Vineet M. Arora, L Vaur, Steven Patterson, T. Heise, Rossi Mce., L. Quarré, D Dorigo, K P Bouter, H Serghides, M. Matsuda, Astrup Av, R Cramb, S Chipchase, Andrzej Lewiński, R Wadwa, C Friedrich, S Giordanetti, Joan Vendrell, Souvik Das, D McGechie, E Locatelli, E Sossidou, D Li, Meinardi, G Thalhammer, Jay S. Skyler, C J Muller, Ulla Feldt-Rasmussen, Susan M. Ring, Richard R. Rubin, S Pramming, Attila Brehm, D Klomp, C Plachot, E Santeusanio, F Roquet, A Naassan, B Pini, Patricia B. Carroll, Maura Pettiti, David S. Rowlands, Jandeleit-Dahm Kam., Timothy M. Frayling, A. K. Sjølie, A. de la Peña, M Franciosi, P A Torjesen, Jonathan C. Levy, S Caruso, B M Sreckovic, S Kim, L Arnaldi, H. B. Holt, M. Parkkonen, Francesco Dotta, M Diamant, H Hilden, A Manginas, N Tsokos, Davis, Barbara Leibiger, M Vaxillaire, V Deschamps, S Hernandez Campos, M Benchimol, Meftun Ahmed, S J Murdoch, Z V Zabarovskaya, Christine Waterman, T Werner, L Brunerova, D Coca-Robinot, D Pejkovic, Jesper Lau, Andreas Melidonis, R A Afonso, V Bronte, W Kotowa, C Broca, Orian S. Shirihai, Stehouwer Cda., Y Nishi, S Wanyonyi, R Fabregate, P A Khanam, S Nepal, Aimin Xu, Jan S. Ulbrecht, S M Ilic, H Hattori, A Panadero Moya, Pietro Castellino, Chiara Guglielmi, Masaru Sakurai, C Barrett, T Trüb, Christine Darwin, S Gross, Carmine Gazzaruso, J Coulaud, L Carbillon, Choi N-H., Anna C. Calkin, U Besenfelder, W Horn, K P Zak, S Nordman, L Zajdenverg, Y Sunaga, G A Spinas, P M Whitty, Kentaro Ohtoshi, Daniela Gasperikova, T Rinaldi, M R Nangle, Vincenzo Positano, C Lasseur, Paul Marsden, M Cinteza, Jeannet Lauenborg, M Párrizas, B Arslan, D Oakley, N S Mason, F Lauster, A B Lowenfels, A H van den Meiracker, M De Smet, P Politakis, Martin Tfj., M Watanabe, Gianna Toffolo, M Kimura, Sudhesh Kumar, A Petrov, G A Raciti, A. M. Umpleby, T Pervin, Maciej T. Małecki, E Tuomilehto-Wolf, Elisabeth R. Mathiesen, R Bonfante, R Gerona, L F Zang, T Sundsten, Mogens Kruhøffer, Johanne Tremblay, Naoto Katakami, L E Foster, Jorge Ferrer, D M Yellon, G Macdonell, T Appl, Levendal R-A., Arany Ejr., B Glisic, R Lestrade, M Dolci, F Pellegrini, K B Rooney, T Ishikawa, H Mayaudon, G Freckmann, V Asnaghi, N Rajkovic, Markus Tiedge, J Marniemi, Jian Peng, D Treacher, P. Z. Zimmet, V Jewhurst, H S Chaudhury, Magnus Møller, E Mathiesen, S Triscornia, Michael Stumvoll, Dirk Wedekind, T Todo, N Schifino, Jacek Kasznicki, C McHorney, Am Sironi, V Patel, N A Abdella, K Ohno, Karin Jandeleit-Dahm, Rafn Benediktsson, K Sztefko, D Yin, Michael R. Christie, J Hill, Simi Ahmed, A Behar, Borys J-M., Don Johns, David G. Armstrong, B Hare, B Szepietowska, S Frojdo, B Meyer, H Hanaire-Broutin, R Reich, A T Ali, A A Dreval, A J Stears, Y Sui, V Mattoo, Wilding Jph., F Azizi, M A Heise, Dana Dabelea, Afshan Siddiq, A. P. Lambert, L Steen, Giuseppe Pugliese, Steen Andersen, F Salman, G Parnaud, Hahn J-U., R A Silvestre, B Idzior-Waluś, B Guy-Grand, Linda D. Voss, Peter G. Jones, E Konoue, G Mello, Vigdis Aas, Yoshifumi Suzuki, Allan Flyvbjerg, L Mogylnytska, J B Hansen, Finn Gustafsson, Jürgen Schrezenmeir, S Kondo, A Ruggiero, I Tarkun, Jan Kopecky, A Umehara, K J Wiefels, D Ogawa, M Austen, F Bataller, John Wahren, Birger Thorsteinsson, G. H. Tomkin, I Pogliaghi, Ahn C-W., M Ishizaki, I Peiró-Martinez, Webb D-L., Ketan Dhatariya, Akihisa Imagawa, Roberto Lupi, P Petit, F Fehse, Jason D. Cooper, Pfeiffer Afh., V Cunsolo, E E Agardh, R Nieuwland, F Ekram, Jensen Rbb., Jens Bülow, HU Häring, Quynh Ntt., D Kawamori, M Herná Alarcó, M Kolpe, Gianfranco Parati, N Labastie, U Mager, D Krenova, M Aragona, Wolffenbuttel Bhr., Pierre Maechler, B P Kovatchev, L Mordhorst, C Coghi, L Wassef, G Füst, Z M Lu, Ewan R. Pearson, D De Cesare, S V McLennan, K Mikoudi, Ali Naji, O Apostolou, A Roussin, J I San Pedro, L N Scherbacheva, A Baroni, McNamara Mrj., M Perez-Maraver, A P Shepelkevich, M Ehren, Alex Harper, C Merezak, M Morrissey, Leena Kinnunen, H Goto, P Maincent, Oluf Pedersen, R. R. Lyu, G Rizzo, V V Bogomolov, N Krasova, G M McGuire, Tina Parkner, A Timi, Johann Bauersachs, S Foussas, S A Schreiber, T Monauni, Schwarz Peh., Allenberg, J D Lee, S Dewan, Y G Zheng, D Carroll, E Sarti, C Wollheim, Anna Kaminski, C Menneila, P Bucher, Xu Jyu., Vincent Rigalleau, A Schöpfer, Hans Jörnvall, A Ben Drief, X Jeunemaitre, E Schuster, Chan Slf., S Bilgic, J Coverly, K Szafraniec, Stalenhoef Afh., H Bergert, David I. W. Phillips, J Maksimovic Pavlovic, Sergio E. Starkstein, E Chaim, T Lehmann-Lintz, P Salacone, Tim Armstrong, Ingrid Klöting, C M Frampton, Franco Cavalot, A.K.Azad Khan, H Rose, Marta Letizia Hribal, Jette Kolding Kristensen, H Gröbe, M Nishi, A Vanderplas, Howlett Hsc., L E Bowen, R Malik, A Wu, Charles C. Richardson, Y Li, P G McNally, Yoon K-H., A Baleydier, M J Murphy, P. M. Nilsson, U Lindblad, Sten Madsbad, T Bíró, Riitta Veijola, Charlotte Glümer, Assunta Pandolfi, Lydia Aguilar-Bryan, M Namba, C Franzen, S Lopatriello, David Russel Jones, S. Cellek, T Derezinski, Ronald P. Stolk, B Yermen, Marina Trento, Christine Feinle-Bisset, T S Futers, Ahn S-K., D Yue, R Nakamura, Shin Tsunekawa, Ortwin Naujok, Marina Vladimirovna Shestakova, Matthew Wintle, M P Guarino, Giovanni Camussi, B Persson, M Brahimi, Raffaella Buzzetti, H Hendrickx, H Schuster, Anthony J. Brookes, N K Hoa, A Ianni Palarchio, T Marte, N H Redemann, M Pufal, Roya Babaei-Jadidi, C Glüimer, Susanne J. Szabo, G Zuodar, Laura Calvillo, M Homering, K Stegner, L Min, Y Haider, S Evangelista, N Soydan, Y Yerushalmy, Z Karimi Anderesi, A Bernjak, Laine A-P., A E Udovichenko, Eva Corpeleijn, A Rieger, Tahseen A Chowdhury, D Schmid, Krystyna Matyka, O V Ivanova, G Ciampittiello, P Vague, I Schmoelzer, Groop P-H., J Weidenhammer, Luis Arnes, A Khoruzhenko, Jelena Skibova, W Jefferson, M Catala, J K Wilson, G Dunseath, A D Tselepis, S. Leotta, A. Sämann, R A Gerber, T Busila, P E Fraser, William J. Jeffcoate, J Pariès, K Huoponen, Anne Jörns, G Shanmugam, A Tsiavou, S Yoshida, Kim M-J., Annapaula Giulietti, S Paillasson, K Tsuchiya, Divyen K Shah, P Saar, S S Juarez, Stefanie Maxion-Bergemann, J Briody, V Schmitz, C M Pena, J Fernádez-Real, S Naruse, M Kalis, A P Klimenko, X H Chen, H.H. Lervang, G Bock, Mirja Tiikkainen, J Potockova, N Pekcanli, George Dragicevic, Timothy M. Rose, David C. Goff, H Komori, V Vasseur-Delannoy, S Hanley, P Hajos, C W Ahn, Matsuoka T-A., J Burns, Petar M. Seferovic, Yuki Kita, K Lyons, K Kohri, Eleftheria Zeggini, Y Ding, G Belcher, Steven V. Edelman, N Dinççaǧ, Christopher J. Rhodes, Manders Rjf., S Giveon, Dario Iafusco, L Li, M C Ribaudo, Kang S-K., Laurie J. Goodyear, L Martinez, C Vermigli, H Dabire, R Raymond, J de Haan, Christopher J. Groves, Å Norberg, H Jahr, M Gloster, Christopher D. Byrne, R Nagase, M Gorska, S Jinagouda, Marcin Baranowski, J M Bruun, L F Fan, Marco Bugliani, Ferdinando Nicoletti, S Born, T Milicic, C Haug, A Imbroinise, Rafael Carmena, G Gedulin, Benoit R. Gauthier, M Ptak, Schweitzer M-A., A Kayserilioǧlu, Rory J. McCrimmon, Ludmila Kazdova, D Pittrow, M Unal, L G Hunsicker, B Komsuoglu, E V Titovich, N L Petrova, M F Saad, T Lindström, D Koev, G Pigas, Pamela Phillips, Timo Otonkoski, S Kanhasura, Ignacio Conget, L Forga, B Rokeya, K Naraine, M Kuroda, F W Hanna, N Hancu, O E Voronko, A Urrutia, E Krusinova, K Stenlof, G. Philippou, W E Brady, Shlomo Sasson, I Cuccuru, S Welte, Md. Shahidul Islam, P Burian, S Creely, B Reinsen, Seema Garg, R Froguel, S Mathi, Myriam Nenquin, R S Crow, L Wogensen, J Brumberg, M Saito, E Hak, C Caravaggi, B Veldman, R E Gregg, A Swaminathan, S Allgauer, F Whitehouse, J Saban-Ruiz, S Rössner, A B Lewandowska, Toshinari Takamura, Elaine M. Dennison, Eugenia Carvalho, Rafael Simó, F Gigli, Chiasson J-L., H Weiss, E Jaeckel, T Krarup Hansen, F Bonnet, J Wu, L A Atramentova, F Murray, Flemming Pociot, A Arne, C. Valadas, F Boomsma, Marketa Sjögren, C Richart, Stefan Schreiber, M M Musri, M Dworacka, E Zakja, Peter Båvenholm, R Gelfand, Steven W. J. Lamberts, Temel Yilmaz, F Péan, K Rave, M Hirata, C Helbig, Y Kido, M Sumarac-Dumanovic, Emma Bingham, N Saadat, L Strindberg, R G Brodows, J Rihl, N C Unwin, Peter Watt, P. Van Rooy, Alexander V. Chibalin, M Michelini, Chantal Mathieu, Samy Hadjadj, W M Sallas, E Schroeder, E Woźniakiewicz, U Golbach, Jeong I-K., M Nam, M Thompson, E Berrone, Leena Ryysy, S Matsuno, G R Fulcher, Jan Schulze, Rachele Berria, Abdol-Reza Esteghamati, Claire Pentecost, D Begic, D Bailbé, J Seo, A Caduff, M Hompesch, E Nishimura, Soroku Yagihashi, Przemysława Jarosz-Chobot, A L Harte, M. E. Trujillo, Dreyfus J-F., G Golor, O Serri, George A. Werther, S Pahler, M Traversa, A. Jotic, I Seljeflot, Renata Krupa, K Irjala, M P Manns, V Sasseville, M R Yun, I Tauveron, Moira Harrison, C Müller-Brandes, Jan Škrha, L Javashvili, C Giusti, Jørgen Rungby, R M Segura, Oh Y-S., P Cavallo Perin, A Piazza, Fumihiko Sakakibara, F Caricato, K Manolopoulos, H. Aladdin, Elena Delgado, C Negut, R Hougaard, H Feldmeier, Francesca Cannata, B Mylari, C Kloos, Xia Li, A Turco, P Thieblot, J Lee, K Koczwara, Gan Huang, I M Briaud, L. Williams, J Ibáñez, Wing-Yee So, Joachim Størling, Kamadjeu Rkk., Sarah J. Bailey, J M González-Posada, M Brändie, M Adiseshiah, N Boschetti, K Tsukiyama, R Iwasa, Naoko Tajima, K K Seah, K Gorbenko, B Saha, Bettina Fischer, M Boronat, Y Kaneko, P K Jaiveer, T Østergård, S Pye, J Rosada, M Fazia, S Duran, Jonas Lindström, Muller Lma., Lee H-C., B Wilke, U Wohlrab, Y López, Philip Hougaard, H B Mortensen, G Riccardi, I Dedov, S Mauri, P G Matthews, D Holt, C Schöfl, N D Hancu, P Tong, Frank Döring, Michael Edmonds, Krystyna Wyka, R Citarrella, M J Mohler, Fabio Vistoli, J Gabaldon, T Gambling, T Barnera, Patrick Gilon, F Hadj Brahim, T M Kuchmerovska, Joachim Spranger, G Collier, Małgorzata Szelachowska, V Hwa, J Herwig, Asish K. Saha, Antje Wienbergen, P Merkouris, V R Driver, G Pellegrini, C Tusek, D Kuhl, J Salvador-Rodríguez, A Rivero, Af Björkesten C-G., L P Aiello, Ángela M. Valverde, A. Sola-Gazagnes, M Lenz, N Duffy, T. Charniauskaya, H Vavrinkova, B B Dokken, N García-Hernandez, M. C. Matteoli, W Neuhuber, B Gutt, Haiyan Wang, C De Tullio, Nikolaos Tentolouris, Susan E. Ozanne, A El-Ouaghlidi, R A Blacken, P K Marsden, S Saragoni, E Fernández, P Thams, Yukio Tanizawa, Cora Weigert, A Bajo-Martinez, A Icks, Yu Liu, Jan Erik Henriksen, J Lupón, C Chrysohoou, C Y Pan, M Enslen, Carsten F. Gotfredsen, S Paxian, C Sert, B Lescrauwaet, Nikolaos Karachalias, Harald Staiger, Soon Dkw., S Mandica, Arild C. Rustan, T Kokko, Luigi Gnudi, L Mantione, Y Mitchel, K Takebayashi, K Lindström, A Akhter, I Calota, Z A Leshchenko, R Henry, E Hagström-Toft, J A Sloniger, C Gredal, Palmer Cna., C Remade, Marion Marchand, S Liew, F Oriente, R Roesen, Ekaterine Bakhtadze, J Bodalski, Věra Lánská, U Baicchi, Terezie Pelikanova, Aniko Varadi, Trudy J. Smith, R Vettermann, Daniel Pipeleers, Becker Rha., S Speier, Saeger H-D., A Tedeschi, Peter J. Grant, W A Scherbaum, R Scardapane, C Arntz, L J Kerr-Bayles, V Poltorack, Sol E-R., G Deniz, Kasper Rossing, Scott J. Jacober, D Lucchesi, Kees J. Gorter, Shin J-S., F Bifari, Ravi Retnakaran, P C Tsiotra, Anna Möllsten, K Mironczuk, A Erdei, Gerry Melino, S G Kauschke, E Stenninger, A Morsanutto, Carmen Fajardo, A. Khan, M S Rasmussen, A Villena, C Ilic, G Gruden, S Uhles, M I Freed, I K Temple, Marco Giorgio, Z Radikova, M Lou, Theodora Temelkova-Kurktschiev, Sorin Ioacara, Patrick A. Ott, Christine Longuet, E Baldassari, Ian Chapman, Cristian Guja, S Seber, K Lundin, Juretschke H-P., A Kanatsuka, Schumicki D-M., Boris Mankovsky, E Liva, Johan Wadén, G Steil, P Chauveau, K Schafer, V Borzì, A S Andersen, D P Mikhailidis, L Groop, Hans J. Arnqvist, M Salvadorini, H. J. Bodansky, Johnny Ludvigsson, A De Paoli, A de Prado, P Olesen, P Syrovatka, V V Klimontov, E Rodriguez, Arthur S. Leon, Alberti Gkm., A Opel, S Kokkoris, S B Hong, Philippe Courtois, L Haque, Maria Sörhede Winzell, M C Beauvois, A Szypowska, D Yu, M Gutniak, D Petzinna, B Isomaa, K S Prickett, Maria Felice Brizzi, Pavel Hamet, P J Hammond, K. F. Michelmore, Yumie Takeshita, N Hariharan, Corrado M. Cilio, G Pogatsa, W G Jerome, E Bartley, K Schlembacher, G Blohmó, Guy A. Rutter, Kyung Mook Choi, S. C Tamer, Felix K. Assah, K A Jandeleit-Dahm, M Chan, H Darius, Jørgen F. P. Wojtaszewski, A Papazisi, M Amaya, A Knopff, M Tadayyon, I J Kim, W Russ, T Myrnäs, M. Tryon, S Poonsatha, Noel Cameron, Kim M-H., Alejandra Tomas, F Homo-Dekarche, G. Di Cianni, M Stotzka, C Solimine, Mikhail Borisovich Antsiferov, H Naserke, M Bianchi-Biscay, J I Lara, Moon C-K., Alain Ktorza, Alison N. Jeffery, V Lilla, Eun Seok Kang, Hanley Ajg., J Widder, R Ratner, C Goretti, P J Weston, J Perkins, V Rasmussen, M Evans, T M Gibson, A Jaffe, S I Chisalita, C Owman, L Hiltunen, E Kakishita, C M Mack, H C Potter, M Femerling, M Desai, M Soinio, K Yang, Patricia L. Brubaker, M Meyer, V Dy, J Berden, R Komers, Milos Adamec, R Petzoldt, Alan G. Robinson, R Stevens, A Doi, A Leunda, Eduard Montanya, Alessandra K Cardozo, N Kraenkel, Claudio Cobelli, U A Mueller, S Yamashiro, B R Gedulin, G Francisco, J Dennenmoser, Lesch K-P., Martin G. Bischof, M Ichita, C Fernandes, Jochen Hampe, S Kern, D Kelly, E Zeender, P Perna, J D Best, A C Calkin, Vivian Fonseca, J Prestle, D G Parkes, Satish K. Garg, T Burrell, B M Fischer, D Kruger, J S Skinner, Lin T-M., Jozef Ukropec, Maria Jeziorska, K Arii, David D. D’Alessio, M B Gomes, L Quandt, I Fragaki, M C Brindisi, A Gladkih, E Kitsou, S Di Cola, T Iwasaki, Peter Diem, T Lakka, V V Popova, G Lee, Hannah J. Welters, K Bonomo, Gavin Kelsey, Y Yerushalmi, A. H. Barnett, H. von Boehmer, K Blomberg, B Haag, M C Preiti, V Sanchez-Margalet, Fowelin Jhr., Y Bernard, M Chalkiadaki, E Grandi, R M Gow, V Schippmann, E. A. M. Gale, R Schiel, R Iwai, O Olari, A Braun, D Koziarska, Bernhard Ludvik, Lee H-W., W P Battisti, N Oliver, M Pankop, H Vertigan, M Pibernik-Okanovic, D Gianneli, J Oh, R Giorgino, M Ballmann, Olle Korsgren, M Pantaleoni, S Zavarella, Göran Sundkvist, Hans Stenlund, Harleah G. Buck, David J. Glass, Morrissey, I Uchimura, M Pugniere, R E Warren, M Mikkola, Baradez M-O., M Weck, C Häuser, D Šrámková, D Voelkel, R Prager, Y L He, M Cornes, O K Vikulova, E Evdemon, Peter R. Cavanagh, Allen Taylor, M Balabolkin, G Schreier, E Stern, J Lips, V Serban, G Sparacino, Roser Casamitjana, Aine McKillop, I Groza, E Bernal, Kathleen M Gillespie, T Ledet, A Garzaniti, F Hawkins, K M Tushaus, C Renaudin, Christina Maier, A Dormi, A Ubertalli, Inge Tetens, M Ostojic, E Pierre-Justin, A Bhushan, E Ur, L I Jeltova, Tilo Moede, E Tibiriça, Zoran Gucev, Knoch K-P., G Pizzolanti, A M Şengül, T P Degenhardt, Cristina Lencioni, M Fitchet, E Santini, E Devangelio, C Panaite, Y I Karachentsev, S B Solerte, Christos Manes, M Lipka, C H Teng, P Mrak, G Fegan, R C Milton, M Negrean, Astrid Plamboeck, L Patti, M Houk, Ritva Kauppinen-Mäkelin, Christoph F Ebenbichler, O Sysoyeva, Frantisek Saudek, H Wysocki, Robert A. Rizza, J Altirriba, Bjørn Richelsen, L. Lam, Rémy Burcelin, A Antsaklis, G Galimberti, R. de Vries, A Lewin, Marcia A. Testa, Lee B-C., M Krauth, A Fonollosa, Marco Cappa, L Rieger, Edoardo Mannucci, André Herchuelz, H Corominola, I Gangat, G Rábago, S Dalla Noce, L Kunselman, J Diehl, M Nattrass, M Kaiser, R Kawamori, E Istoc, Á Pintér, D G Maggs, T Aoki, Csaba Szabó, B Oguzhan, Roberto Ferrari, D M Schumann, Yang Y-W., Hideaki Kaneto, Q Chai, E Blase, Katarzyna Wozniak, D Quijada, George Dailey, U Stier, M Skowronski, Thierry Berney, Adria Giacca, M Askenas, C Tikellis, T Zima, M Lufuma, P T Sawicki, M Dundua, Y Kitahara, M Winter, Janet Lutale, David E. Kelley, Alicia Acitores, Erion, Matthias Möhlig, S Dalal, Birgit Rami, Monster Tbm., Michael Horowitz, L A Leiter, Neil B. Ruderman, David R. Hadden, Mark Walker, I Garai, Michel Polak, A Somogyi, C G Walker, Claes-Göran Östenson, Ou H-C., Thomas Haak, G Kouri, W Pusch, J Fabrin, Robyn J. Tapp, E Zander, B Todorova, Peter Damm, Mine Yilmaz, Michel Pinget, Aila Rissanen, K Leppert, Darren J. Kelly, R B Zaid, A Bohbot, U Fennenkötter, Margot Umpleby, H Rodriguez-Rosas, R. Edwards, J Boavida, S Micheletti, E Bouskela, J Kreuder, N Mizutani, Pardo Icg., R Haberl, S Georgia, D Choi, Monika Lechleitner, R Guerrero, C G Bala, S Y Kim, R Oates, C Miele, E Witthaus, T Sakai, Albert Lecube, Anne Sofie Astrup, Teppo A-M., Margareta Norberg, G Dakovska, I Spanopoulos, P. Djordjevic, Nikolai Petrovsky, J M Fernández-Real, NanWei Tnw., Bilo Hjg., D L Lawlor, E J Henriksen, Anette-Gabriele Ziegler, A McDougall, L Wong, M G Choi, Connie S Karschimkus, M Zaramella, M Gallo, I. G. Lawrence, Viswanathan Mohan, L Valera, H V Silveira, C Pitsavos, Kasper Hermansen, Cloos Pac., K F Hanssen, Samuel W. Cushman, Juergen Eckel, R E Hamman, N Scheffler, C Lengyel, D Bakri, M Fukuda, P Rossetti, A Heerschap, Barbara A. Fielding, Choi Y-H., M Massi-Benedetti, Mykola Khalangot, F. Campi, W A Al Dahi, G Hu, Q Dang, J Ruzickova, A Lifshitz, L M Scheek, A Penfornis, S.C. Campbell, T S Filters, A T Shearer, A Morosanu, M Yngen, K Dezaki, C Damgé, Robert B. Wallace, Neil Portwood, M Henricsson, M Yazawa, J Yantha, G Tepohl, Christopher S. Wendel, Oliveira Jep., R Tracy, M Schindler, M Nabli, H Hosoda, Linda Boselli, B Kunselman, Mentink Cja., L Waselle, P Šamalíková, J Kirchheiner, S Sejil, D Beebe, James D. Otvos, J. J. Holst, J. B. Lopes de Faria, Marian Rewers, Kenneth Cusi, Geng Y-J., F Esfahanian, Francesco Giorgino, D. Freedenberg, R De Caterina, J Seufert, M N Kerstens, W Sturm, M Fujiyama, Konstantinos Makrilakis, A Novials, Lars Berglund, P Strange, W Shim, Clive J. Petry, Michelle M Jack, A E Panteleon, S Wiltshire, G Radulian, C Leperlier, N Téllez, O Sekine, M Karlén, Noël C. Barengo, Qing Qiao, Christian Benedict, C H Saely, M Yoneda, C Gonzalez-Villalpando, Sara Giunti, W Roth, S Wein, E Com, Martin J. Stevens, Giovanni Ghirlanda, Darin Acosta, J Hokanson, M Hauschild, L. A. Powell, Vondra K, Haering H-U., F Afifiyan, K Bendtzen, D M Todd, Marc Y. Donath, Arleta Rewers, Francesco Prisco, R Maeda, A B Kanstrup, M Prats, Y Toledano, Timothy W. Jones, Simon C. Potter, Per Løgstrup Poulsen, M Ligueros-Saylan, Mark L. Evans, Jarl S Torgerson, G Zerbini, L A Ivanova, E Ohmura, C. Kupich, K. Yasuda, J Leprince, A Alaveras, R Ruetter, Kevin C.R. Baynes, Harald Sourij, Y Aramaki, du Prel J-B., Józef Drzewoski, van den Ouweland Jmw., Jochen Seissler, Iain D. Wilkinson, Irina A. Bondar, Y R Yu, S Miclea, S Galatius, T. Havrdova, L Montoya, M Zeller, G C Jones, R B Amazonas, T K Guseva, A Davidescu, Stavros Bousboulas, A. Sandbaek, C Ito, H Taniguchi, M L Simoons, Lars Weinehall, H. Boeing, M A Tambascia, R Grempler, C Speed, A M Mkrtum'yan, A A Darekar, K Hu, Firth Rgr., I Östlund, S Kawazu, P Chitson, B Perry, Joel Dunn, D G Rouiller, K Wagner, Oleg Dyachok, Algis J. Vingrys, S Habu, Mariella Trovati, H Sobajima, Pierre Lecomte, Kim T-H., D Virsaladze, M Oprean, F Pullen, A Rußmann, G J Bruining, Martina Düfer, Wen Xu, Min Y-K., Norman E Cameron, Gianfranco Pagano, K Harley, M Su, J P Le Berre, Sian Ellard, S Howard, D Russell-Jones, Z Li, S Carpenter, E L Thomas, W Tang, Lee M-S., N Ubrich, M. M. McMahon, G Vassilikos, N Brossa, M S Joergensen, S Smith, A Vania, Y Laurent, S Basir, A Freudenthaler, Sally M. Marshall, D Niedermayer, V I Pankiv, J Mentel, S Pruna, J M Pou Torelló, Y Ito, G Chrysos, Werner Kramer, Hironori Yamasaki, L Bowman, F Palumbo, P Ruth, G Lankas, Z H Liao, D Park, W Otter, C Montrone, Sevasti Zervou, Jennifer L. Wilkinson-Berka, Bo Feldt-Rasmussen, I Banu, Paolo Sbraccia, Bani Mukhopadhyay, Mark E. Cooper, M Kidron, Pål R. Njølstad, A M Jonsdottir, M R Burge, G Valpiani, Yutaka Oiso, David J. Hill, T Koch, J Park, A J Plaschke, M P Pye, A Totonelli, S Caronna, B Cremonesi, C Müller, K Tarhzaoui, Valentina Marchetti, M Rodier, Moshe Hod, C N Dang, Trevor A. Howlett, S J Thomas, C Penny, A. de Leiva, Gerald Vervoort, Ghislaine Fontés, Agnieszka Szadkowska, I Al-Zakwani, A Manari, M Eigenthaler, A. Björklund, K Nabe, Mohammad Abdur Rashid, Philips J-C., K Rebrin, Stefan Müller, Claus Thorn Ekstrøm, A A Papageorgiou, L Franco, Paul Hjemdahl, Martine Laville, Flemming S Nielsen, A I Vinik, P Perelli Cippo, Mikael Lehtihet, M Zairis, H Takahashi, M Pietryga, M Kameyama, Jens Knudsen, W W Lautt, Z Rušavý, G Milic, E Pedersen, U Krause, B Balletshofer, J Reviriego, A Scatena, H C Chen, V Gottschall, Alberto Piaggesi, J Gebbie, Maurizio Galderisi, K Nikkiä, A Blayo, D S Fosmark, DL Eizirik, K Busch, Francesco Beguinot, F Capani, A Carrillo, L Nährlich, Thomas Høi-Hansen, Bernard Charbonnel, Edith Schober, Ananda Basu, Deborah J. Smyth, Gerd Plewe, S Vahsen, Claire Levy-Marchal, B S Hansen, V Holtman, S Roche, C Whiteside, A E Fowler, K Helleberg, M Gerl, G Jerums, L Menditto, G Dell'Antonio, A Miles, E Kahan, M Kaibara, V A Serhiyenko, Cees J. Tack, M Shamkhalova, T Linn, R. Koznarova, O Oliyarnyk, Regine Bergholdt, Margaret C. Cam, Matthew Knuiman, U Guiducci, Joanne E. Curran, V Qvisth, F Horkay, Brun J-M., J Jurado, Markku Saraheimo, S Kaltenbach, D D Yin, E Mukai, M Schlosser, Kilbane, K Kølendorf, Hsu Y-J., Steen Gammeltoft, M S Mizel, U Müller, J Bothner, H C Schønheyder, M Ho, I B Bauche, A Etemadi, R F Urdaneta, A Kocijančič, Kim K-R., P E Carey, Olov Rolandsson, S Bochnig, Takahisa Hirose, Baldomero González, Banga J-D., S Vol, R P Hill, F Velazquez, Kathryn Mitchell, S Bott, Z Ma, Richard E Gilbert, D. Mills, A K Gosby, Alison M. Thomas, D Alexander, W Tanaka, Klaus Badenhoop, N D Thuan, B Otto, Gisela Drews, Rui Duarte, S Cantaro, Boulton Ajm., Hélène Hanaire, A Gorski, L Prieto-Sanchez, M Shestakova, Xiaoning Fan, M Higa, J Gurushankar, T Kunitou, D D Trifunovic-Zamaklar, J Nourooz-Zadeh, T F Ørntoft, G Doronzo, P Levéen, B Geloneze, C Fotino, D W Quinn, A Wojciechowska-Luźniak, G Mazzilli, Kook Hwan Kim, M Kaplar, L Dzneladze, Gregory J. Cooney, M Stahlhut, Frances L. Game, E J Bastyr, R Hiles, S. Mariz, T R Pieber, Howlett Hcs., J H Wilmore, Cha B-S., J M Brown, C Laue, Fiona M. Gribble, Susan E. Manley, D L Linemeyer, S G Ashwell, R Sabbah, Hisamitsu Ishihara, N Tronko, M Pohl, H Tindali, Lam Ksl., K Vollmer, I Nagaev, F. Gras, M Corfini, D Lyngsø, A M Sanigorski, Aldo Galluzzo, Alessandro Roberto Dodesini, E Shishko, H Moustgaard, S Piquer, O Tenberken, Ingrid Mühlhauser, A Sturk, Dianne L. Wingate, C Albala, Marie Degerblad, A Kubaszek, Gary W. Cline, J F Markman, J Louw, Y A Redkin, J E Shaw, Gaetano M. De Ferrari, R M Budzinski, I A Snegurakaya, P Kühnen, D Mustapic, Bo Ahrén, C Laflor, Eva Fisher, A Semplicini, C Pandolfo, Myriam Khaldi, K Mattila, Stella Pelengaris, Olga Kordonouri, M Nagao, P I Mansell, K Rduch, R Fahey, R Filipczak, M Suetsugu, J C Vitoria, J Baumert, J Stewart, R S Bonser, Jean Tichet, Christer Andersson, A Şengül, McCuaig, Zorenc Ahg., Xiuqing Guo, H Jordan, K Bieback, Daniela Dietze-Schroeder, J Shin, S Ohga, J Lademann, K C Turner, I V Shutichina, M. Shamkhalova, K Rowley, Rosario Rizzuto, Saraheimo, G. da Silva Xavier, Doss W. Neal, K Akram, H Virtamo, E Dios, K Begum, A Pfuetzner, Tsvetalina Tankova, S Katayama, Christoph Otto, Philip J. Barter, K Zitouni, R Madonna, S Söderberg, S Diaz-Troya, Leszek Czupryniak, S Dietz, P Luźniak, K S Nair, Mark A. Myers, L L Want, S Shaikh, Wolfgang Rathmann, E Wozniakiewicz, L Jönsson, Pernille Poulsen, D F Orr, A B Hauber, F Kelly, Carlo Maria Rotella, J V Costa, Elaine Vieira, E Grodzinsky, Lilianna Majkowska, E Draeger, S Näf, Philip Clarke, S Akter, A Bagust, A Vassibosis, E Lourida, P Chase, G Mardarowicz, Carlo Ricci, A Ugalde-Canitrot, A Wutte, R Streicher, P Ebeling, Taishan Zheng, Marcus Korn, K Summers, Lennarth Nyström, Y Kaburagi, T Furuta, S Freeman, D Skoutas, A A Serhiyenko, K Tryfinopoulou, I. P. Gray, Peter Bjerregaard, R H Elder, M Hosokawa, Marcela Brissova, Kent D. Taylor, R. Da Ros, Carolyn F. Deacon, Andrew D. Morris, N Aydin, Alicia J. Jenkins, L M Serhiyenko, M Sjöstrand, M A Sayeed, A Ardelean, Rolf Holle, I Broom, Giuseppina Imperatore, Massimo Federici, W Sajid, C Bradley, C V Phenekos, W Leonhardt, L Bahia, Veitenhansl, M, Stegner, K, Hierl, F, Dieterle, C, Feldmeier, H, Gutt, B, Landgraf, R, Garrow, A, Vileikyte, L, Findlow, A, Waterman, C, Boulton, A, Shankhdhar, K, Shankhdhar, L, Shankhdhar, U, Petrova, N, Foster, A, Edmonds, M, Ferraresi, R, Caravaggi, C, De Giglio, R, Cavaiani, P, Pogliaghi, I, Sommariva, E, Katz, I, Harlan, A, Miranda palma, B, Prieto sanchez, L, Armstrong, D, Bowker, J, Mizel, M, Cernea, S, Wohlgelernter, J, Kidron, M, Modi, P, Raz, I, Arbit, E, Nosek, L, Kapitza, C, Beckett, P, Gelfand, R, Goldberg, M, Heise, T, Testa, M, Turner, R, Hayes, J, Scranton, R, Simonson, D, Yang, Y, Hsu, Y, Naujok, O, Francini, F, Jörns, A, Tiedge, M, Lenzen, S, Abdel wahab, Y, Marenah, L, Orr, D, Shaw, C, Flatt, P, Chokkalingam, K, Mansell, P, Clausen, P, Ekbom, P, Damm, P, Feldt rasmussen, U, Nielsen, B, Mathiesen, E, Feldt rasmussen, B, Dewan, S, Da Silva, N, Ternan, P, Leong, K, Wilding, J, Asatiani, N, Kurashvili, R, Dundua, M, Shelestova, E, Pagava, K, Ramazashvili, M, Hod, M, Smirnov, S, Petersen, J, Justesen, T, Ringholm Nielsen, L, Müller, C, Højlund, K, Wensaas, A, Kase, E, Aas, V, Rustan, A, Thoresen, G, Levin, K, Beck nielsen, H, Gaster, M, Im, S, Kang, S, Kim, S, Ahn, Y, Lihn, A, Schmoll, D, Werner, T, Kienitz, A, Meyer, M, Barthel, A, Ailett, F, Sutherland, C, Walther, R, Grempler, R, Sasson, S, Reich, R, Tenenbaum, T, Alpert, E, Anfossi, G, Russo, I, Traversa, M, Massucco, P, Mattiello, L, Doronzo, G, Trovati, M, Lally, S, Tan, C, Owens, D, Tomkin, G, Porchay, I, Péan, F, Bellili, N, Betoulle, D, Balkau, B, Tichet, J, Marre, M, Fumeron, F, Chatellier, G, Alhenc gelas, F, Nichols, G, Brown, J, Hayes, R, Bowman, L, Drexel, H, Saely, C, Marte, T, Benzer, W, Langer, P, Hoefle, G, Moll, W, Aczel, S, Karagiannis, E, Lübben, G, Urquhart, R, Edwards, G, Bruce, S, Howlett, H, Cugnardey, N, Turner, K, Park, J, Fiedorek, F, Avogaro, A, Gallo, A, Pinton, P, Rizzuto, R, Murphy, E, Ceolotto, G, Caterson, I, Guy grand, B, Hill, J, Barone, M, Aiello, A, Allochis, G, Borzì, V, Cannatà, F, Caronna, S, D'Avanzo, A, Elli, R, Formoso, G, Paroli, A, Scardapane, R, Sorichetti, P, Tatti, P, Viviani, G, Santeusanio, F, Manzella, D, Grella, R, Abbatecola, A, Paolisso, G, Søndergaard, L, Monster, T, Johnsen, S, Olsen, M, Mclaughlin, J, Sørensen, H, Lervang, H, Rungby, J, Lyssenko, V, Fredriksson, J, Almgren, P, Anevski, D, Orho melander, M, Sjögren, M, Tuomi, T, Groop, L, Jaziri, R, Aubert, R, Tuomilehto, J, Hu, G, Jousilahti, P, Peltonen, M, Lindstrom, J, Laina, A, Alevizaki, M, Philippou, G, Souvatzoglou, A, Anastasiou, E, Alba, S, Metcalf, B, Voss, L, Jeffery, A, Wilkin, T, Glüimer, C, Colagiuri, S, Vistisen, D, Borch johnsen, K, Haynes, A, Bower, C, Bulsara, M, Jones, T, Davis, E, Mortensen, H, Hougaard, P, Holl, R, Swift, P, Pociot, F, Knip, M, Hansen, L, Szadkowska, A, Pietrzak, I, Zmysłowska, A, Wyka, K, Bodalski, J, Swift, R, Hougaard, R, Gerstl, E, Engelsberger, I, Rabl, W, Rosenbauer, J, Gröbe, H, Hofer, S, Krause, U, Dabelea, D, Morgan, T, Pettitt, D, Dolan, L, Mayer davis, E, Pihoker, C, Hillier, T, Imperatore, G, Ruggiero, A, Hamman, R, Stylianou, A, Tentolouris, N, Perrea, D, Tselepis, A, Lourida, E, Kitsou, E, Katsilambros, N, Vedovato, M, Dodesini, A, Lepore, G, Tiengo, A, Trevisan, R, Penno, G, Miccoli, R, Pucci, L, Lucchesi, D, Bandinelli, S, Fotino, C, Triscornia, S, Baldassari, E, Del Prato, S, Reboldi, P, Santeusanio, E, Fuller, J, Langham, R, Gow, R, Zhang, Y, Kelly, D, Christensen, P, Parving, H, Gilbert, R, Chibalin, A, Zhong, Z, Kotova, O, Davidescu, A, Ehrén, I, Ekberg, K, Wahren, J, Wassef, L, Buckley, A, Rooney, K, Briody, J, Thompson, M, Ozanne, S, Thompson, C, Chamson reig, A, Summers, K, Arany, E, Hill, D, Solerte, S, Gazzaruso, C, Locatelli, E, Precerutti, S, Schifino, N, Ferrari, E, Fioravanti, M, Phenekos, C, Ginis, A, Fragaki, I, Chalkiadaki, M, Tzioras, C, Powell, L, Mcguire, G, Jewhurst, V, Trimble, E, Rasmussen, B, Vessby, B, Uusitupa, M, Berglund, L, Pedersen, E, Riccardi, G, Rivellese, A, Tapsell, L, Hermansen, K, Da Silva Xavier, G, Rutter, J, Rutter, G, Briaud, I, Lingohr, M, Dickson, L, Mccuaig, J, Lawrence, J, Rhodes, C, Wikstrom, J, Katzman, S, Shirihai, O, Yang, J, Deng, S, Wang, X, Hessner, M, Wu, J, Wong, R, Sukumvanich, S, Markman, J, Naji, A, Wolf, B, Gao, Z, Rubi, B, Del Arco, A, Satrústegui, J, Maechler, P, Del Guerra, S, Lupi, R, Bugliani, M, Sbrana, S, Torri, S, Boggi, U, Vistoli, F, Mosca, F, Marchetti, P, Rennings, A, Smits, P, Stewart, M, Tack, C, Li, L, Nyström, T, Gutniak, M, Ahrén, B, Holst, J, Sjöholm, Å, Gomes, M, Cailleaux, S, Tibiriça, E, Albertini, J, Chen, H, Mather, R, Valensi, P, Chisalita, S, Arnqvist, H, Kraenkel, N, Adams, V, Linke, A, Gielen, S, Schuler, G, Humbrecht, R, Cipollone, F, Iezzi, A, Fazia, M, Pini, B, Cucurullo, C, De Cesare, D, Schmidt, A, Mazurek, T, Zang, L, Mannion, J, Diehl, J, Martin, J, Martella, A, Zalewski, A, Shi, Y, Otter, W, Winter, M, Doering, W, Standi, E, Schnell, O, Kragelund, C, Køber, L, Faber, J, Hildebrandt, P, Steffensen, R, Pankowska, E, Szypowska, A, Lipka, M, Herwig, J, Scholl schilling, G, Böhles, H, Robertson, K, Schönle, E, Gucev, Z, Mordhorst, L, Tamer, S, Gall, M, Ludvigsson, J, Hoogma, R, Hammond, P, Gomis, R, Kerr, D, Bruttomesso, D, Bouter, P, Wiefels, K, De La Calle, H, Schweitzer, D, Pfohl, M, Torlone, E, Krinelke, L, Conget, I, Storms, F, Rodriguez, J, Leperlier, C, Davies, M, Peter, R, Luzio, S, Dunseath, G, Miles, A, Hare, B, Backx, K, Pauvaday, V, Caselli, A, Marfia, G, Battista, C, Veves, A, Spallone, V, Uccioli, L, Gonzalez, J, Peyrot, M, Rubin, R, Leventhal, H, Scheffler, N, Ulbrecht, J, Cavanagh, P, Perrin, N, Oglesby, A, Bastyr, E, Ziegler, D, Siekierka kleiser, E, Meyer, B, Schweers, M, Selvarajah, D, Wilkinson, I, Emery, C, Shaw, P, Griffiths, P, Tesfaye, S, Obrosova, I, Arezzo, J, Phillips, K, Gribble, F, Williams, L, Reimann, F, Iakoubov, R, Whiteside, C, Brubaker, P, Acitores, A, González, N, Sancho, V, Valverde, I, Villanueva peñacarrillo, M, Martín duce, A, Trigo, M, Arnés, L, Burkart, V, Ichino, N, Ohashi, A, Klein, B, Paxian, S, Schmid, R, Karlsen, A, Heding, P, Frobøse, H, Rønn, S, Kruhøffer, M, Ørntoft, T, Nerup, J, Mandrup poulsen, T, Billestrup, N, Cardozo, A, Ortis, F, Feng, Y, Rasschaert, J, Van Eylen, F, Storling, J, Herchuelz, A, Eizirik, D, Wang, H, Kouri, G, Wollheim, C, Ribaux, P, Hammar, E, Parnaud, G, Rouiller, D, Bosco, D, Halban, P, Midthjell, K, Carlsson, S, Grill, V, Lau, C, Færch, K, Glümer, C, Tetens, I, Jørgensen, T, Tillin, T, Forouhi, N, Mckeigue, P, Chaturvedi, N, Zethelius, B, Hales, C, Berne, C, Coleman, R, Stevens, R, Holman, R, Christensen, J, Sandbæk, A, Lauritzen, T, Irwin, N, Gault, V, Green, B, Harriott, P, O'Harte, F, Bouman, S, Ursø, B, Brand, C, Rolin, B, Ribel, U, Schäffer, L, Maggs, D, Ceriello, A, Frias, J, Wang, Y, Ruggles, J, Kolterman, O, Piconi, L, Weyer, C, Want, L, Ratner, R, Uwaifo, G, Thornberry, N, Eiermann, G, Kim, D, Lankas, G, Leiting, B, Li, Z, Lyons, K, Petrov, A, Sinha Roy, R, Woods, A, Woods, J, Zhang, B, Fisher, M, Moller, D, Weber, A, Dreyer, M, Bellin, C, Schmitz, V, Roesen, R, Nescheret, A, Bose, A, Mocanu, M, Carr, R, Yellon, D, Manolopoulos, K, Born, S, Wagner, A, Jeziorska, M, Ben Drief, A, Bashir, M, Tomlinson, D, Malik, R, Zeymer, U, Schwarzmaier d'assie, A, Petzinna, D, Chiasson, J, Stratton, I, Af Björkesten, C, Fagerudd, J, Rosengård bärlund, M, Forsblom, C, Pettersson fernholm, K, Waden, J, Saraheimo, M, Rönnback, M, Thorn, L, Groop, P, Mollsten, A, Svensson, M, Kockum, I, Rudberg, S, Brismar, K, Dahlquist, G, Hovind, P, Hansen, T, Tarnow, L, Thiel, S, Jensen, B, Flyvbjerg, A, Kankova, K, Hertlova, M, Krusova, D, Schwenke, S, Ott, J, Thom, S, Mistry, P, Sjolie, A, Larsen, B, Witt, N, Hughes, A, Samira, H, Lahiry, S, Howlader, S, Parveen, S, Azad Khan, A, Clarke, P, Gray, A, Phillips, L, Phillips, P, Chittleborough, C, Baldock, K, Taylor, A, Davis, W, Davis, T, Knuiman, M, Hendrie, D, Worthley, D, Nicolucci, A, Pellegrini, F, De Berardis, G, Franciosi, M, Belfiglio, M, Rossi, M, Sacco, M, Valentini, M, Richardson, C, Jones, P, Persaud, S, Hussain, K, Clark, A, Christie, M, Gniuli, D, Hribal, M, Accili, D, Khan, M, Zervou, S, Cheung, L, Abouna, S, Ifandi, V, Pelengaris, S, Luco, R, Ferrer, J, Ma, D, Shield, J, Dean, W, Leclerc, I, Knauf, C, Burcelin, R, Kelsey, G, Powers, A, Shostak, A, Ferrara, N, Poffenberger, G, Jerome, W, Brissova, M, Geloneze, S, Tambascia, M, Pareja, J, Chaim, E, Silveira, H, Geloneze, B, Ravikumar, B, Carey, P, Snaar, J, Dheelchand, D, Cook, D, Neely, D, Taylor, G, Morris, P, Taylor, R, Stears, A, Masding, M, Wootton, S, Sandeman, D, Klimes, I, Wein, S, Gasperikova, D, Ukropec, J, Wiernsperger, N, Sebokova, E, Manco, M, Mingrone, G, Granato, L, Greco, A, Nanni, G, Castagneto, M, Vidal, H, Calvani, M, Ferrannini, E, Alvarsson, M, Sundkvist, G, Lager, I, Henricsson, M, Berntorp, K, Fernqvist forbes, E, Steen, L, Örn, T, Shutler, S, Bianchi biscay, M, Rosenstock, J, Sugimoto, D, Strange, P, Stewart, J, Soltes Rak, E, Dailey, G, Kloos, C, Müller, U, Sämann, A, Femerling, M, Risse, A, Jecht, M, Haak, T, Garg, R, Lawrence, I, Akinsola, M, Mcnally, P, Garber, A, Kim, H, Draeger, E, Aydın, L, Şengül, A, Kürklü, A, Uçak, S, Basat, O, Seber, S, Altuntaş, Y, Jin, J, Yu, Y, Yu, H, Zhang, X, Mattoo, V, Eckland, D, Widel, M, Duran, S, Fajardo, C, Strand, J, Knight, D, Oakley, D, Tan, M, Sato, A, Nagao, M, Aki, N, Nakagami, T, Iwamoto, Y, Zhou, Z, Li, X, Huang, G, Yan, X, Yang, L, Peng, J, Wang, J, Tan, S, Tang, W, Fürnsinn, C, Brunmair, B, Wagner, L, Gras, F, Artwohl, M, Zierhut, B, Waldhäusl, W, Shine, B, Hopkins, D, Anand, V, Lim, E, Raval, U, Sharp, P, Corder, R, Lipkin, D, Lahiri, A, Bartnik, M, Rydén, L, Ferrari, R, Malmberg, K, Pyörälä, K, Simoons, M, Standl, E, Soler soler, J, Öhrvik, J, Bruce, D, Starkstein, S, Schauer, U, Astrup, A, Pietraszek, L, Nielsen, F, Rossing, P, Ali, S, Smidt, U, Yokoyama, H, Pavkov, M, Knowler, W, Bennett, P, Nelson, R, López alba, A, Morcillo, L, Caballero, A, Montoya, L, Jiménez, A, Maceira, B, Lewis, J, Ravid, M, Wajman, A, Tadgell, C, Remuzzi, G, Hunsicker, L, Wadén, J, Wessman, M, Taskinen, M, Pugliese, G, Amadio, L, Menini, S, Oddi, G, Ricci, C, Iacobini, C, Pricci, F, Sorcini, M, Pesce, C, Migliaccio, E, Giorgio, M, Pelicci, P, Di Mario, U, Lassila, M, Jandeleit dahm, K, Seah, K, Calkin, A, Allen, T, Cooper, M, Lopes De Faria, J, Cavakcanti, T, Silva, K, Ferrari, A, Cellek, S, Foxwell, N, Cotter, M, Cameron, N, Tennagels, N, Jordan, H, Stahl, P, Voss, M, Welte, S, Werner, U, Lehmann, R, Moeschel, K, Baumgartner, F, Oeckinghaus, A, Beck, A, Weigert, C, Hennige, A, Schleicher, E, Häring, H, Müssig, K, Staiger, H, Natalicchio, A, Laviola, L, De Tullio, C, Renna, L, Giorgino, R, Giorgino, F, Falasca, M, Maffucci, T, Park, D, Song, J, Lee, D, Lee, Y, Hariharan, N, Kunselman, L, Gu, L, Sasseville, V, Harrity, T, Cheng, P, Pratley, R, Schweizer, A, Mills, D, Ahren, B, Kim, T, Song, X, Van Poelje, P, Potter, S, Dang, Q, Fujitaki, J, Linemeyer, D, Landau, B, Erion, M, Pankop, M, Golay, A, Després, J, Sjöström, L, Lawlor, D, Legg, K, Ur, E, Houweling, S, Kleefstra, N, Meyboom de Jong, B, Bilo, H, Schlömer, G, Meyer, G, Kasper, J, Mühlhauser, I, Young, B, Taylor, J, Friede, T, Hollis, S, Mason, J, Long, A, Gambling, T, Pauline, L, Burns, E, New, J, Gibson, M, Betteridge, D, Leiter, L, Whitty, P, Eccles, M, Hawthorne, G, Grimshaw, J, Steen, I, Vanoli, A, Wood, L, Speed, C, Mcdowell, D, Rewers, M, Maahs, D, Wadwa, R, Eckel, R, Tracy, R, Pfützner, A, Strotmann, H, Schulze, J, Hohberg, C, Pahler, S, Forst, T, Ambery, P, Sydall, H, Cooper, C, Dennison, E, Sayer, A, Barker, D, Phillips, D, Lalic, N, Ostojic, M, Lalic, K, Zamaklar, M, Jotic, A, Ilic, M, Rajkovic, N, Lukic, L, Milicic, T, Vergès, B, Zeller, M, Steg, P, Beer, J, Brisard, C, Brindisi, M, Dentan, G, Laurent, Y, Janin manificat, L, Makki, H, Ravisy, J, Cottin, Y, Ajjan, R, Grant, P, Futers, T, Carter, A, Rasmussen, M, Bruun, J, Pedersen, S, Richelsen, B, Dietze schroeder, D, Sell, H, Koenen, M, Eckel, J, Delporte, M, Bauche, I, Brichard, S, Ait El Mkadem, S, Rezsohazy, R, Tsiotra, P, Tsigos, C, Gatsiou, C, Raptis, S, Walker, C, Bryson, J, Hancock, D, Takahashi, N, Hatakeyama, H, Kasai, H, Gauthier, B, Iezzi, M, Fukuda, M, Duhamel, D, Ravier, M, Düfer, M, Neye, Y, Krippeit drews, P, Sausbier, U, Arntz, C, Sausbier, M, Neuhuber, W, Ruth, P, Drews, G, Beauvois, M, Rolland, J, Jonas, J, Merezak, C, Henquin, J, Gilon, P, Jabin Gustafsson, A, Dzabic, M, Islam, M, Vaxillaire, M, Cheyssac, C, Dina, C, Vasseur delannoy, V, Leprêtre, F, Siddiq, A, Froguel, P, Neve, B, Fernandez zapico, M, Ashkenazi katalan, V, Urrutia, R, Melloul, D, Froguel, R, Poulsen, P, Wojtaszewski, J, Richter, E, Vaag, A, Granhall, C, Renström, E, Luthman, H, Isomaa, B, Gloyn, A, Edghill, E, Pearson, E, Mackay, D, Temple, I, Noyes, K, Freedenberg, D, Gillespie, K, Lambert, A, Gale, E, Ellard, S, Hattersley, A, Fanelli, C, Porcellati, F, Rossetti, P, Busciantella, N, Billi, C, Burrin, D, Bolli, G, Bingham, E, Dunn, J, Sutcliffe goulden, J, Marsden, P, Amiel, S, Davis, R, Kennedy martin, T, Peters, J, Wittrup jensen, K, Mcewan, P, Morrissey, M, Currie, C, Akram, K, Pedersen bjergaard, U, Thorsteinsson, B, Pibernik okanovic, M, Peros, K, Begic, D, Szabo, S, Metelko, Z, Vlaiculescu, M, Calota, I, Busila, T, Bruckner, I, Giannakopoulou, D, Lindner, H, Hrachovinova, T, Fejfarova, V, Csémy, L, Malcomson, J, Campbell, M, Pandolfi, A, Giardinelli, A, Di Tomo, P, Di Silvestre, S, Di Fulvio, P, Capani, F, Consoli, A, Roesen, P, Patruno, A, Grilli, A, Capani, R, Felaco, M, Boner, G, Mccarroll, K, Brenner, B, De Zeeuw, D, Kowey, P, Shahinfar, S, Crow, R, Iso, K, Kuboki, K, Tada, H, Yoshino, G, Schjoedt, K, Andersen, S, Distiller, L, Degenhardt, T, Szabo, J, Khalifah, R, Schotzinger, R, Achenbach, P, Knopff, A, Naserke, H, Ziegler, A, Bonifacio, E, Valera, L, Jardin, B, Roche, S, Lampasona, V, Pugniere, M, Roquet, F, Granier, C, Laune, D, Afifiyan, F, Cheung, R, Yantha, J, Jackowski, G, Dosch, H, Nakanishi, K, Kogawa, N, Komatsu, Y, Fontés, G, Imamura, T, Ilic, C, Puech, C, Ktorza, A, Bataille, D, Dalle, S, Fosgerau, K, Gelling, R, Nishimura, E, Andersen, B, Madsen, P, Lau, J, Streicher, R, Wagner, K, Vettermann, R, Potterat, O, Renard, E, Panteleon, A, Kolopp, M, Rebrin, K, Steil, G, Hariri, F, Darwin, C, Saad, M, Buckingham, B, Kunselman, B, Wong, L, Istoc, E, Leach, J, Purvis, R, Monfre, S, Fischer, J, Garg, S, Ahmann, A, Ruchti, T, Gandhi, G, Nuttall, G, Mullany, C, Schaff, H, Williams, B, Rizza, R, Mcmahon, M, Gates, G, Mentel, J, Smith, R, Crook, J, Hosszúfalusi, N, Vatay, Á, Palik, È, Füst, G, Karádi, I, Romics, L, Pánczél, P, Aurich, K, Voelker, U, Braun, A, Nguyen, L, Kriketos, A, Denver, G, Üceyler, N, Schütt, M, Lesch, K, Mössner, R, Sommer, C, Seda, O, Liska, F, Kazdova, L, Sedova, L, Krenova, D, Zima, T, Tremblay, J, Kren, V, Hamet, P, Klöting, N, Follak, N, Klöting, I, Dessapt, C, Dei Cas, A, Baradez, M, Hayward, A, Thomas, S, Viberti, G, Gnudi, L, Gale, C, Thallas, V, Thomas, M, Candido, R, Burns, W, Forbes, J, Shymanskyy, I, Kuchmerovska, T, Klimenko, A, Jaeckel, E, Manns, M, Von Boehmer, H, Hedrich, H, Téllez, N, Montolio, M, Estimes, E, Rodríguez mulero, S, Soler, J, Montanya, E, Liu, Y, Chen, J, Rowlands, D, Chan, H, Simeonov, I, Anthony, K, Zelaya, F, Williams, S, Brammer, M, Mountjoy, P, Bailey, S, Shaw, J, Sicree, R, Dunstan, D, Cameron, A, Zimmet, P, Hewitt, S, Graff iversen, S, Assah, F, Fezeu, L, Kengne, A, Awah, P, Mbanya, J, Shu, J, Kamadjeu, R, Kiawi, E, Kerényi, Z, Péterfalvi, A, Bosnyák, Z, Madarász, E, Tabák, Á, Szánthó, J, Rákóczi, I, Tamás, G, Di Bartolo, P, Valpiani, G, Di Martino, M, Scaramuzza, A, Saragoni, S, Degli Esposti, E, Cannatá, F, Gudbjornsdottir, S, Cederholm, J, Nilsson, P, Eliasson, B, Miettinen, M, Miettinen, J, Nan, H, Dong, Y, Gao, W, Sun, B, Wang, N, Fu, F, Shi, H, Ding, M, Lorenzo, C, Serrano ríos, M, Martínez larrad, M, González sánchez, J, Seclén, S, Villena, A, Gonzalez villalpando, C, Williams, K, Stern, M, Haffner, S, Sakurai, M, Miura, K, Kita, Y, Takamura, T, Ota, T, Ishizaki, M, Morikawa, Y, Nakagawa, H, Szybiński, Z, Szurkowska, M, Mardarowicz, G, Łopatyński, J, Gilis januszewska, A, Szafraniec, K, Nicer, T, Kwon, H, Lee, J, Lee, H, Park, Y, Choi, Y, Jang, S, Song, B, Yoon, K, Lee, W, Cha, B, Lee, K, Son, H, Jørgensen, M, Moustgaard, H, Bjerregaard, P, Ebara, F, Salmon, J, Owen, N, Welborn, T, Armstrong, T, Jolley, D, Galtier, F, Deschamps, V, Borys, J, Lasfargues, G, Andre, P, Born, C, Royer, B, Wilpart, E, Cailleau, M, Eschwege, E, Timar, R, Serban, V, Vlad, A, Diaconu, L, Rosu, M, Olari, O, Sima, A, Qiao, Q, Chappuis, B, Diem, P, Christ, E, Iafusco, D, Prisco, F, Gemma, C, Mattera, S, Sanges, M, Menneila, C, Sommese, L, Jarosz chobot, P, Polanska, J, Feltbower, R, Mckinney, P, Stephenson, C, Bodansky, H, Icks, A, Du Prel, J, Grabert, M, Giani, G, Kyvik, K, Skytthe, A, Ioacara, S, Farcasiu, E, Bradescu, O, Guja, C, Scutaru, G, Savu, O, Ionescu tirgoviste, C, Ola, T, Hawa, M, Buzzetti, R, Scherbaum, W, Kolb, H, Thivolet, C, Hunter, S, Hadden, D, Guntram, S, De Leiva, A, Mauricio, D, Pozzilli, P, Leslie, R, Benediktsson, R, Jonsdottir, A, Einarsdottir, A, Reynisdottir, I, Aspelund, T, Grant, S, Thorleifsson, G, Sigurdsson, G, Stefansson, K, Gudnason, V, Wollitzer, A, Jovanovic, L, Lobo, P, Martí, M, Preiti, M, Urdaneta, R, Juarez, S, Schober, E, Thon, A, Rami, B, Tringham, J, Buyukbese, M, Sakamoto, Y, Inoue, Y, Matsumoto, H, Oono, K, Tokumasa, Y, Gorter, K, Janssen, P, Stolk, R, Van Hessen, P, Rutten, G, Palik, É, Niedermayer, D, Murro, A, Coghi, C, Federici, M, Benedetti, M, Koehler, C, Henkel, E, Temelkova kurktschiev, T, Stier, U, Ott, P, Siegert, G, Bergmann, S, Hanefeld, M, Leonhardt, W, Sayeed, M, Mahtab, H, Khanam, P, Banu, A, Rashid, M, Mulnier, H, Seaman, H, Lovell, D, Soedamah mathu, S, Colhoun, H, Lawrenson, R, Diehm, C, Lange, S, Darius, H, Pittrow, D, Haberl, R, Von Stritzky, B, Tepohl, G, Allenberg, J, Trampisch, H, Soinio, M, Marniemi, J, Laakso, M, Lehto, S, Rönnemaa, T, Ito, C, Sasaki, H, Ishida, S, Maeda, R, Barengo, N, Lakka, T, Köhler, C, Benke, I, Raccah, D, Bailleau, C, Vexiau, P, Vaur, L, Aydin, N, Topsever, P, Filiz, T, Dayan, A, Bulgurlu, S, Gebeloglu, N, Demirtunc, R, Dagar, A, Skliros, E, Sotiropoulos, A, Vassibosis, A, Xipnitos, C, Liva, E, Chronopoulos, I, Merkouris, P, Skourtis, S, Pappas, S, Charbonnel, B, Baigts, F, Dumenil, V, Paillasson, S, Baleydier, A, Hanaire, H, Sert, C, Chabrier, G, Rodier, M, Fontaine, P, Kim, J, Miyake, Y, Sakai, T, Takamatsu, K, Tomioka, Y, Sugano, H, Murao, S, Shimizu, I, Unwin, N, Nag, S, Roglic, G, Connolly, V, Roper, N, Goodwin, J, Kelly, W, Thomsen, R, Hundborg, H, Schønheyder, H, Khalangot, M, Gang, H, Tajima, N, Bianchi, C, Giovannitti, M, Pellegrini, G, Caricato, F, Bertolotto, A, Corfini, M, Guzder, R, Gatling, W, Byrne, C, Varillas, V, Boronat, M, Carrillo, A, La Roche, F, Ojeda, A, López, Y, Marrero, D, Nóvoa, J, Shahidul Alam Khan, A, Thaware, P, Gangat, I, Howlett, T, Jenum, A, Holme, I, Birkeland, K, Sourij, H, Stoschitzky, K, Klein, W, Roth, M, Dittrich, P, Wascher, T, Hilding, A, Eriksson, A, Agardh, E, Efendic, S, Östenson, C, Levitt, N, Bradshaw, D, Salzsieder, E, Freyse, E, Rutscher, A, Heinke, P, Augstein, P, Makino, H, Kainou, Y, Konoue, E, Ohno, K, Ebisui, O, Fujii, Y, Kondo, S, Fujiyama, M, Tanaka, K, Takemoto, K, Kida, K, Onuma, Y, Osawa, H, Tuomilehto wolf, E, Kinnunen, L, Laine, A, Kokko, T, Kakko, T, Hermann, R, Veijola, R, Simell, O, Ilonen, J, Guglielmi, C, Galgani, A, Beretta Anguissola, G, D'Avola, D, Bakhtadze, E, Weiss, H, Wedekind, D, Bilbao, J, San Pedro, J, Vitoria, J, Martul, P, Castaño, L, Badenhoop, K, Ramos Lopez, E, Usadel, K, Wägner, A, Cloos, P, Stahlhut, M, Bergholdt, R, Ramos, E, Taxvig, C, Vella, A, Smyth, D, Cooper, J, Undlien, D, Rønningen, K, Ionescu tîrgovişte, C, Savage, D, Dunger, D, Strachan, D, Ring, S, Todd, J, Mironczuk, K, Kretowski, A, Kinalska, I, Nutland, S, Guja, L, Nielsen, L, Gammeltoft, S, Schwarz, P, Towers, W, Fischer, S, Mcrae, J, Willis, J, Scott, R, Potter, H, Merriman, T, Frampton, C, George, P, Spranger, J, Möhlig, M, Hoffmann, K, Müller, S, Osterhoff, M, Ristow, M, Boeing, H, Pfeiffer, A, Li, Y, Fisher, E, Burwinkel, B, Schrezenmeir, J, Mager, U, Pulkkinen, L, Lindi, V, Lindström, J, Xiu, L, Sui, Y, Weng, J, Kalis, M, Cilio, C, Olde, B, Owman, C, Levéen, P, Da Ros, R, Assaloni, R, Maier, A, Quagliaro, L, Zuodar, G, Zakja, E, Gu, H, Nordman, S, Brookes, A, Prince, J, Helwig, U, Rubin, D, Hampe, J, Schreiber, S, Fölsch, U, Döring, F, Porzio, O, Massa, O, Cunsolo, V, Njolstad, P, Terrinoni, A, Melino, G, Colombo, C, Federici, G, Barbetti, F, Herder, C, Bongardt, F, Schöpfer, A, Rathmann, W, Martin, S, Holle, R, Thorand, B, Wichmann, H, Koenig, W, Illig, T, Blasiak, J, Arabski, M, Krupa, R, Wozniak, K, Dabrowski, J, Kasznicki, J, Zurawska, M, Drzewoski, J, Kose, H, Matsumoto, K, Wilke, B, Kerr bayles, L, Walder, K, Civitarese, A, Jowett, J, Curran, J, Elliott, K, Trevaskis, J, Bishara, N, Wanyonyi, S, Sanigorski, A, Blangero, J, Kissebah, A, Collier, G, Carlsson, E, Arner, P, Ridderstråle, M, Nitz, I, Lindner, I, Suzuki, S, Hinokio, Y, Hirai, M, Yamada, T, Yoshizumi, S, Tanizawa, Y, Matsutani, A, Ishihara, H, Takahashi, K, Katagiri, H, Oka, Y, Nam, M, Hong, S, Ahn, C, Kim, Y, Zeggini, E, Parkinson, J, Groves, C, Frayling, T, Hitman, G, Walker, M, Sampson, M, Levy, J, Weedon, M, Wiltshire, S, Owen, K, Halford, S, Mccarthy, M, Shehadeh, N, Bakri, D, Gershoni baruch, R, Yasuda, K, Okada, T, Sunaga, Y, Kajimoto, Y, Shibasaki, T, Kaburagi, Y, Kadowaki, T, Estalella, I, Rica, I, Vazquez, J, De Andrade, P, Van Den Ouweland, J, Maassen, J, Huoponen, K, Savontaus, M, Dimitrijevic Sreckovic, V, Djordjevic, P, Popovic, S, Gostiljac, D, Canovic, F, Sreckovic, B, Colak, E, Obrenovic, R, Milic, G, Glisic, B, Etemadi, A, Saadat, N, Azizi, F, Tsur, A, Cohen, Y, Yerushalmi, Y, Wainstein, J, Norberg, M, Eriksson, J, Lindahl, B, Andersson, C, Rolandsson, O, Stenlund, H, Weinehall, L, Lecomte, P, Vol, S, Cacès, E, Chabrolle, C, Halimi, J, Nijpels, G, Dekker, J, Bouter, L, Heine, R, Löbner, K, Mollenhauer, U, Baumgarten, A, Com, E, Sargin, M, Karadeniz, S, Sengul, A, Suleymanoglu, Y, Pekcanli, N, Yilmaz, T, Cicero, A, Dormi, A, Miconi, A, D'Addato, S, Laghi, L, Brillante, R, Bernardi, R, Grandi, E, Gaddi, A, Jones, M, Lacey, L, Bergenheim, K, Yamagata, F, Yamakoshi, M, Takahashi, M, Kawazu, S, Festa, A, Hanley, A, Otvos, J, Goff, D, Wajngot, A, Cerasi, E, Baumert, J, Schneider, A, Löwel, H, Roussel, R, Müller brandes, C, Ballmann, M, Nährlich, L, Thalhammer, G, Nastoll, M, Schwarz, J, Johne, U, Erfurth, M, Lüddeke, H, Liebl, A, Kotowa, W, Maclaine, G, Evers, T, Pontiroli, A, Pizzocri, P, Paganelli, M, Folli, F, Jung, D, Park, M, Henriksen, J, Durck, T, Weghuber, D, Roden, M, Tura, A, Pacini, G, Bischof, M, Widhalm, K, Sharp, G, Shanmugam, G, Straub, S, Michael, D, Chow, R, Regazzi, R, Gerona, R, Martin, T, Waselle, L, Tomas, A, Min, L, Pessin, J, Björklund, A, Ma, Z, Portwood, N, Parton, L, Smith, E, Diraison, F, Tsuboi, T, Lehtihet, M, Webb, D, Honkanen, R, Knoch, K, Meisterfeld, R, Bergert, H, Kolpe, M, Altkrüger, A, Saeger, H, Solimena, M, Haspel, D, Aguilar bryan, L, Bryan, J, Ullrich, S, Berchtold, S, Ranta, F, Seebohm, G, Alexander, D, Wulff, P, Kuhl, D, Lang, F, Speier, S, Yang, S, Rose, T, Rupnik, M, Varadi, A, Mitchell, K, Schwappach, B, Bleck, C, Wienbergen, A, Rustenbeck, I, Vieira, E, Gylfe, E, Seissler, J, Wohlrab, U, Schmiegelt, D, Ruetter, R, Herten, M, Lechner, A, Nolan, A, Blacken, R, Habener, J, Gao, R, Ustinov, J, Korsgren, O, Mikkola, M, Lundin, K, Otonkoski, T, Jahr, H, Bieback, K, Kern, S, Brendel, C, Brendel, M, Bretzel, R, Taniguchi, S, Ohgawara, H, Tsuchiya, K, Tsuchiya, M, Okochi, H, Kelter, A, Dohrmann, C, Austen, M, Aicher, B, Maedler, K, Schumann, D, Iwakura, Y, Donath, M, Peter, A, Opel, A, Seufert, J, Fernández, E, Serradas, P, Martín, M, Plachot, C, Bailbé, D, Gangnerau, M, Gavete, M, Fajardo, S, Escrivá, F, Portha, B, Álvarez, C, Lipsett, M, Jamal, A, Hanley, S, Castellarin, M, Rosenberg, L, Bhushan, A, Georgia, S, Calderari, S, Meile, M, Miettinen, P, Palgi, J, Virkamäki, A, Ferris, W, Campbell, S, Armstrong, L, Hole, N, Lako, M, Macfarlane, W, Barbera, A, Altirriba, J, Nadal, B, Larsen, M, Gotfredsen, C, Reusens, B, Sparre, T, Kalbe, L, Leunda, A, Kruhoffer, M, Orntoft, T, Remade, C, Dasilva Xavier, G, Motakis, E, Nason, G, Leibiger, B, Berggren, P, Leibiger, I, Uhles, S, Moede, T, Welters, H, Senkel, S, Erdmann, S, Thomas, H, Morgan, N, Irminger, J, Rickenbach, K, Jackson, D, Chan, S, Dezaki, K, Watanabe, M, Hosoda, H, Kangawa, K, Yada, T, Kühnen, P, Laubner, K, Hernández, R, Silvestre, R, Egido, E, Châtenet, D, Leprince, J, Chartrel, N, Vaudry, H, Marco, J, Zhang, F, Zhang, Q, Tengholm, A, Thore, S, Costes, S, Longuet, C, Broca, C, Baltrusch, S, Dyachok, O, Thams, P, Anwar, M, Capito, K, Radu, R, Fujimoto, S, Mukai, E, Shimono, D, Nabe, K, Shimodahira, M, Kominato, R, Aramaki, Y, Yamada, Y, Seino, Y, Giroix, M, Agascioglu, E, Courtois, P, Malaisse, W, Sener, A, Piquer, S, Barcelo batllori, S, Julia, M, Li, J, Lou, M, Zhang, J, Zhou, Q, Zhao, G, Webb, G, Dalal, S, Garcia, C, Saxena, P, Houk, M, Nenquin, M, Abdel ghany, M, Miele, C, Romano, C, Corbo, V, Maitan, M, Andreozzi, F, Ungaro, P, Oriente, F, Raciti, G, Formisano, P, Beguinot, F, Mcclenaghan, N, Mccluskey, J, Patterson, S, Efanov, A, Sewing, S, Bokvist, K, Gromada, J, Frederiksen, A, Juhl, C, Schwarts, M, Schmitz, O, Andersen, P, Valeri, C, Castelli, M, Bonfante, R, Beyan, H, Elouil, H, Khaldi, M, Evangelista, S, Zeender, E, Berney, T, Franklin, I, Sergeev, P, Chervonsky, A, Nyblom, H, Ahmed, M, Bergsten, P, Sol, E, Kharroubi, I, Ladriere, L, Cnop, M, Moffitt, J, Fielding, B, Currie, J, Staiger, K, Brandhorst, D, Winter, D, Kellerer, M, Oprescu, A, Naassan, A, Klimentova, T, Constantin, S, Tang, C, Uchino, H, Lam, L, Wheeler, M, Fantus, G, Giacca, A, Ortsäter, H, Sundsten, T, Youshikawa, H, Winzell, M, Montrone, C, Martemucci, S, Perrini, S, Caccioppoli, C, Størling, J, Grassetti, D, Scipioni, A, Dotta, F, Yamamoto, N, Tsunekawa, S, Ito, Y, Oiso, Y, Miura, Y, Niki, I, Scrocchi, L, Ha, K, Wang, F, Chen, Y, Wu, L, Fraser, P, Yermen, B, Lilla, V, Kaminski, A, Mathe, Z, Dupraz, P, Zbinden, M, Filo, A, Bucher, P, Rinsch, C, Thorens, B, Pepper, M, Estilles, E, Sigrist, S, Rieger, L, Mandes, K, Bohbot, A, Pinget, M, Kessler, L, Parab, P, Katdare, M, Galande, S, Saha, B, Yoshida, A, Satoh, J, Homo dekarche, F, Coulaud, J, Durant, S, Drexhage, H, Mabley, J, Deb, A, Wallace, R, Pacher, P, Elder, R, Szabo, C, Schlosser, M, Mentel, R, Moya suri, V, Wassmuth, R, Gürtler, L, Ankelo, M, Westerlund, A, Blomberg, K, Hinkkanen, A, Popova, V, Gruzov, M, Afanasyeva, V, Kulikovskaya, A, Melnichenko, S, Mankovsky, B, Zak, K, Koczwara, K, Warncke, K, Kawasaki, E, Imagawa, A, Uchigata, Y, Kobayashi, M, Abiru, N, Yamasaki, H, Eguchi, K, Chrul, S, Polakowska, E, Heinrich, A, Walter, M, Pitocco, D, Visalli, N, Crinò, A, Costantino, F, Manfrini, S, Spera, S, Suraci, C, Patera, P, Matteoli, M, Schiaffini, R, Ghirlanda, G, Leotta, S, Hatziagelaki, E, Tsiavou, A, Degiannis, D, Chaidaroglou, A, Manginas, A, Koniavitou, K, Desai, M, Williams, A, Horton, V, Bingley, P, Cull, C, Citarrella, R, Richiusa, P, Mattina, A, Criscimanna, A, Mantione, L, Bronte, V, Pizzolanti, G, Galluzzo, A, Giordano, C, Giulietti, A, Stoffels, K, Overbergh, L, Mathieu, C, Bilgic, S, Aktas, E, Salman, F, Yillar, G, Yilmaz, M, Deniz, G, Valorani, G, Pozzilli, R, Weets, I, Truyen, I, Verschraegen, I, Van Der Auwera, B, De Schepper, J, Dorchy, H, Lebrethon, M, Van Gaal, L, Van Rooy, P, Pipeleers, D, Gorus, F, Shtandel, S, Atramentova, L, Karachentsev, Y, Kravchun, N, Koval, S, Poltorak, V, Levchenko, T, Snegurakaya, I, Miloslavskiy, D, Bojko, V, Resnik, L, Chico, A, Rojas, I, Julià, M, Novials, A, Bendlová, B, Včelák, J, Vaňková, M, Šrámková, D, Šamalíková, P, Kvasničková, H, Vondra, K, Petrone, A, Vania, A, Zavarella, S, Alemanno, I, Di Cola, S, Ribaudo, M, Leonetti, F, Angel, B, Carrasco, E, Santos, J, Albala, C, Oyarzún, A, Pérez bravo, F, Petry, C, Ong, K, Michelmore, K, Artigas, S, Wingate, D, De Zegher, F, Ibáñez, L, Prestle, J, Adomeit, A, Hammer, E, Zieher, T, Missler, B, Appl, T, Schindler, M, Brodbeck, K, Machicao, F, Just, M, Færgeman, N, Knudsen, J, Quint, M, Tschank, G, Korn, M, Henriksen, E, Dokken, B, Sloniger, J, Dörig, J, Quarré, L, Piatkiewicz, P, Taton, J, Czech, A, Gorski, A, Jebens, E, Brennesvik, E, Ktori, C, Ruzzin, J, Shepherd, P, Jensen, J, Lakka, H, Rankinen, T, Leon, A, Skinner, J, Wilmore, J, Rao, D, Bouchard, C, Vendrell, J, Chacon, M, Garcia españa, A, Fernandez real, J, Gutierrez, C, Richart, C, Takeshita, Y, Shimizu, A, Hamaguchi, E, Kaneko, S, Hřebíček, J, Orel, M, Lichnovská, R, Gwozdziewiczová, S, Chlup, R, Faturos, I, Tournis, S, Fotinakis, P, Thomakos, P, Manousaki, M, Leontsini, D, Taxildaris, K, Mitrakou, A, Hur, K, Shim, W, Cho, Y, Lim, S, Kim, K, Beregszaszi, M, Chevenne, D, Sebag, G, De Kerdanet, M, Huet, F, Polak, M, Lacombe, D, De Paoli, A, Levy marchal, C, Mokhort, T, Shishko, E, Shepelkevich, A, Benito, M, Arribas, M, Valverde, A, Menghini, R, Marchetti, V, Cardellini, M, Sbraccia, P, Lauro, D, Lauro, R, Ali, A, Penny, C, Van Der Merwe, M, Paiker, J, Psaras, G, Ekram, F, Crowther, N, Musri, M, Corominola, H, Casamitjana, R, Párrizas, M, Renström, F, Burén, J, Park, C, Lee, G, Kang, E, Sanchez margalet, V, Gonzalez yanes, C, Diaz troya, S, Rodriguez De Fonseca, F, Mcnamara, M, Boschetti, N, Schmid, D, Spinas, G, Trüb, T, Niessen, M, Kuhlmann, J, Neumann haefelin, C, Belz, U, Juretschke, H, Kramer, W, Herling, A, Markova, I, Oliyarnyk, O, Cahova, M, Manders, R, Koopman, R, Zorenc, A, Keizer, H, Van Loon, L, Straczkowski, M, Kowalska, I, Dzienis straczkowska, S, Nikolajuk, A, Gorska, M, Zabielski, P, Baranowski, M, Gorski, J, De Haan, J, Klomp, D, Heerschap, A, Corpeleijn, E, Budzinski, R, Stengele, I, Schuler, M, Selzle, N, Lehmann lintz, T, Heckel, A, Vavrinkova, H, Meskhishvili, E, Furier, S, Parkes, H, Cooney, G, Alemzadeh, R, Tushaus, K, Nencioni, S, Giovannitti, G, Longo, V, De Vries, R, Kerstens, M, Van Tol, A, Dullaart, R, Mcbride, R, Denke, M, Pearson, T, Battisti, W, Brady, W, Palmisano, J, Tuzova, O, Wahl, H, Hong, Q, Luz, K, Xu, G, Schmülling, R, Liebich, H, Oomen, P, Hattori, H, Smit, A, Scheek, L, Thomaseth, K, Lajoix, A, Gauthey, A, Dietz, S, Jahannault, C, Manteghetti, M, Petit, P, Gross, R, Ostenson, C, Quynh, N, Florén, A, Langel, U, Gedulin, B, Smith, P, Prickett, K, Tryon, M, Barnhill, S, Yeoh, T, Young, A, Hiles, R, Carpenter, T, Serota, D, Schafer, K, Ross, P, Nelson, D, Rebelatto, M, Ikeda, H, Nagashima, K, Tsukiyama, K, Todo, T, Trombetta, M, Boselli, L, Calì, A, Cretti, A, Monauni, T, Bifari, F, Bonora, E, Muggeo, M, Bonadonna, R, Gredal, C, Rosenfalck, A, Dejgaard, A, Hilsted, J, Vankova, M, Sramkova, D, Samalikova, P, Vcelak, J, Kvasnickova, H, Bendlova, B, Rudovich, N, Rochlitz, H, Ritzel, R, Butler, A, Butler, P, Murphy, M, Körner, A, Csillag, J, Pintér, Á, Toman, M, Gray, I, Vielwerth, S, Rinnov, A, Jensen, R, Juul, A, Uitterlinden, P, Bruining, G, Lamberts, S, Rasmussen, E, Malis, C, Ekstrom, C, Arne, A, James, J, Thomas, P, Cavan, D, Owona, A, Ozaki, R, So, W, Tong, P, Chan, M, Wong, G, Cockram, C, Chan, J, Redemann, N, Götz, B, Lahm, P, Mader, G, Tadayyon, M, Oh, Y, Schippmann, V, Kluge, R, Bornstein, S, Joost, H, Bae, H, Lee, B, Vertigan, H, Carroll, D, Griffiths, L, Coghlan, M, Freeman, S, Toffolo, G, Dalla Man, C, Basu, R, Cobelli, C, Bertoldo, A, Price, J, Mathis, C, Mason, N, Holt, D, Kelley, C, Mckolanis, T, Kelley, D, Whyte, M, Jackson, N, Beale, R, Treacher, D, Carroll, P, Jones, R, Umpleby, M, Jaquet, D, Boiko, J, Rigal, O, Czernichow, P, Lévy marchal, C, Qvisth, V, Hagström toft, E, Moberg, E, Bolinder, J, Sjöstrand, M, Gudbjörnsdottir, S, Strindberg, L, Lönnroth, P, Mick, D, Sumarac dumanovic, M, Cvijovic, G, Kendereski, A, Pejkovic, D, Zoric, S, Casanueva, F, Dieguez, C, Singh, R, Basu, A, Chittilapilly, E, Johnson, M, Abdallah, B, Shubeska Stratrova, S, Svendsen, O, Dhatariya, K, Bigelow, M, Nair, K, Lundgren, M, Rüge, T, Myrnäs, T, Gimeno, R, Suri, V, Li, D, Huard, C, Martinez, R, Vettore, M, Sironi, A, Gastaldelli, A, Mari, A, Ciociaro, D, Buzzigoli, E, Pettiti, M, Positano, V, Lombardi, M, Radziuk, J, Pye, S, Brehm, A, Krssak, M, Bernroider, E, Anderwald, C, Nowotny, P, Cline, G, Shulman, G, Kotsa, K, Papazisi, A, Spanopoulos, I, Giovos, I, Suzuki, A, Sobajima, H, Naruse, S, Kitagawa, M, Ishiguro, H, Futakuchi, S, Goto, H, Hines, G, Kennedy, I, Matthews, D, Radikova, Z, Koska, J, Ksinantova, L, Imrich, R, Huckova, M, Vigas, M, Wallace, T, Rajala, U, Hiltunen, L, Keinänen kiukaanniemi, S, Noh, J, Choi, N, Chung, J, Min, Y, Lee, M, Holt, H, Wood, P, Darekar, A, Gross, S, Matthies, K, Weck, M, Malinska, H, Beifort, R, Berria, R, Defronzo, R, Cusi, K, Gorshunska, M, Karachenzev, Y, López bermejo, A, Pratt, K, Hwa, V, Recasens, M, Broch, M, Rosenfeld, R, Fernández real, J, Ricart, W, Grunnet, L, Pedersen, B, Franke, B, Fleming, S, Lemke, N, Laue, C, Pfeuffer, M, Lecube, A, Hernández, C, Genescà, J, García, L, Francisco, G, Simó, R, Kraml, P, Syrovatka, P, Brunerova, L, Smejkalova, V, Potockova, J, Andel, M, Leshchenko, Z, Poltorack, V, Krasova, N, Gladkih, A, Yang, K, Chamson, A, Thyssen, S, Rojo Llobet, A, Christoffersen, B, Raun, K, Fledelius, C, Vinterby, A, Golozoubova, V, Afonso, R, Ribeiro, R, Macedo, M, Guarino, M, Yang, G, Kurita, S, Misu, H, Akahori, H, Cerf, M, Nkomo, X, Muller, C, Du Toit, D, Louw, J, Wolfe coote, S, Nikishin, P, Zagayko, A, Taylor, K, Guo, X, Langefeld, C, Cur, J, Jinagouda, S, Bowden, D, Hokanson, J, Rotter, J, Liew, C, Wise, S, Yeo, K, Teng, C, Fisher, F, Trujillo, M, Hanif, W, Mcternan, P, Barnett, A, Scherer, P, Kumar, S, Kaltenbach, S, Stumvoll, M, Mlynarski, W, Zmyslowska, A, Andrzejewski, W, Shojaee moradie, F, Das, S, Stolinski, M, Jefferson, W, Cramb, R, Shahmanesh, M, Lyngsø, D, Simonsen, L, Bülow, J, Meinardi, J, Sluiter, W, Wolffenbuttel, B, Bonnet, F, Guebre egziabher, F, Rabasa, R, Laville, M, Gosby, A, Maloney, C, Haering, H, Patarrao, R, Lautt, W, Correia, N, Santos, A, Leite, V, Boavida, J, Nanwei, T, Bobbioni harsch, E, Lehmann, T, Sztajzel, J, Morel, P, Huber, O, Chassot, G, Assimacopoulos jeannet, F, Gedulin, G, Baron, A, Hendrickx, H, Lane, J, Coverly, J, Simcox, J, Stocks, J, Brown, L, Beha, A, Juretschke, P, Gerl, M, Klebach, M, Biemer daub, G, Pérez del pulgar, S, Zorzano, A, Heinsbroek, A, D'Alessio, D, Van Dijk, G, Tornero, M, Bailey, C, Mack, C, Wilson, J, Parkes, D, Kusunoki, M, Sakakibara, F, Kato, K, Okabayashi, N, Nakamura, T, Miyata, T, Habu, S, Nakamura, R, Nakasone, Y, Yasaka, T, Ishihara, R, Morikawa, R, Otake, K, Nakaya, Y, Ruzickova, J, Rossmeisl, M, Flachs, P, Sponarova, J, Prazak, T, Matejkova, O, Kopecky, J, Gram, D, Liu, W, Bödvarsdóttir, T, Hansen, J, Sturis, J, Kern, W, Hallschmid, M, Benedict, C, Schultes, B, Born, J, Fehm, H, Westerbacka, J, Lammi, K, Häkkinen, A, Rissanen, A, Yki järvinen, H, Mayr, P, Mertl roetzer, M, Lauster, F, Pohl, M, Lerch, M, Haslbeck, M, Eriksen, J, Rahlfs, V, Serhiyenko, V, Serhiyenko, A, Serhiyenko, L, Radulian, G, Vladica, M, Panaite, C, Balas, B, Derosa, G, Dumas, A, Fiorito, A, Prieto, P, Cancelas, J, Loba, J, Czupryniak, L, Bialasiewicz, P, Pawlowski, M, Nowak, D, Dupuy, O, Le Berre, J, Bordier, L, Rousseau, C, Mayaudon, H, Bauduceau, B, Bossi, A, Meregalli, G, Balini, A, Berzi, D, Cremonesi, B, Cerrato, D, Rezzani, C, Tumiati, M, Han, K, Min, K, Kim, E, Ahn, K, Ahn, H, Argüelles, I, Forga, L, Izquierdo, M, Gorostiaga, E, Fuentes, C, Ibáñez, J, Rivero, A, Baynes, K, Pentecost, C, Bell, J, Thomas, E, Umpleby, A, Kuhl, J, Ruderman, N, Musi, N, Goodyear, L, Patti, M, Thorell, A, Nygren, J, Ljungkvist, O, Degerblad, M, Ståhle, A, Brismar, T, Saha, A, Båvenholm, P, Aydemir, D, Kiran, B, Unal, M, Okumus, N, Kayserilioglu, A, Perkins, J, Kıran, B, Ünal, M, Salman, S, Yıllar, G, Özer, E, Kayserilioǧlu, A, Yılmaz, T, Dinççaǧ, N, Tikkanen, H, Macdonald, A, Harrison, M, Dickinson, H, Bone, A, Watt, P, Østergård, T, Short, K, Saltin, B, Di Mauro, M, Papalia, G, Battiato, R, Giuffrida, D, Boemi, G, Castellino, P, Akter, S, Akhter, A, Pervin, T, Ahmed, S, Ahmed, K, Saleh, F, Chaudhury, H, Tankova, T, Dakovska, G, Lazarova, M, Dakovska, L, Kirilov, G, Koev, D, Torgerson, J, Hauptman, J, Boldrin, M, Pan, C, Gao, Y, Lindgärde, F, Broom, I, Takeda, H, Oana, F, Matsuzawa, A, Hashizume, H, Akahane, S, Cornes, M, Lund, S, Poulsen, G, Frandsen, M, Pedersen, O, Pankiv, V, Yngen, M, Hjemdahl, P, Wallén, N, Florow, D, Leyck Dieken, M, Kitahara, Y, Mine, T, Konya, H, Hamaguchi, T, Satani, K, Umehara, A, Ishikawa, T, Kohri, K, Hasegawa, Y, Suehiro, A, Kakishita, E, Namba, M, Liao, Z, Yao, B, Belcher, G, Mariz, S, Moules, I, Butzer, R, Langenfeld, M, Köder, C, Majali, K, Adiseshiah, M, Betteridge, J, Pratipanawatr, T, Chotmongkol, R, Kanhasura, S, Pratipanawatr, W, Miyazaki, Y, Matsuda, M, Nagasawa, T, Kuroda, J, Dey, D, Chovatia, M, Nag, A, Pandey, B, Nag, B, Thomas, L, Krauth, M, Allgauer, S, Besenfelder, U, Dennenmoser, J, Moon, C, Chae, S, Kim, M, Jo, Y, Shin, J, Ahn, S, Lee, S, Panadero Moya, A, Rodriguez, E, Gonzalo, A, Sánchez vilar, O, Lara, J, Rovira, A, Otto, C, Otto, B, Göke, B, Parhofer, K, Juurinen, L, Tiikkainen, M, Graner, M, Bajaj, M, Suraamornkul, S, Ucak, S, Kurklu, A, Argon, D, Canbek, E, Altuntas, Y, Schöfl, C, Franzen, C, Gregg, R, Swaminathan, A, Frost, C, Nepal, S, Raymond, R, Mosqueda garcia, R, Johns, D, Gilmore, K, Perriello, G, Pampanelli, S, Di Pietro, C, Rinaldi, T, Brunetti, P, Oshinyemi, K, Garcia, S, Curtis, P, Zambanini, A, Home, P, Pocock, S, Dargie, H, Komajda, M, Jones, N, Münscher, C, Potthoff, F, Golbach, U, Weidenhammer, J, Kusterer, K, Lundershausen, R, O'Neill, M, Goldstein, B, Wooddell, M, Strow, L, Waterhouse, B, Cobitz, A, Wyne, K, Porter, L, Weston, W, Chen, T, James, R, Kravitz, B, Pinkowski, D, Ruxer, J, Mozdzan, M, Siejka, A, Kaiser, M, Häuser, C, Jacober, S, Zagar, A, Althouse, S, Pinaire, J, Becker, R, Frick, A, Rave, K, Moses, R, Ways, K, Krones, R, Basir, S, Klein, C, Sawicki, P, Rotella, C, Pala, L, Dicembrini, I, Mannucci, E, Annuzzi, G, De Natale, C, Bozzetto, L, Patti, L, Cipriano, P, Campaigne, B, Malone, J, Bai, S, Reviriego, J, Augendre ferrante, B, Schneider, K, Schweitzer, M, Fach, E, Busch, K, Karimi Anderesi, Z, Haupt, A, Eckert, H, Peiker, J, Fritsche, A, Janka, H, Plewe, G, Kliebe frisch, C, Maxeiner, S, Teng, L, Chan, C, Ernest, C, Skrivanek, Z, Brodows, R, Soon, D, Chung, K, Rußmann, A, Ryysy, L, Hänninen, J, Hulme, S, Kauppinen mäkelin, R, Lahdenperä, S, Lehtonen, R, Levanen, H, Nikkiä, K, Tulokas, T, Virtamo, H, Vahatalo, M, Fulcher, G, Lavalle gonzalez, F, De La Pena, A, Lim, M, Scholtz, H, Derezinski, T, Gerber, R, Hauber, A, Bolinder, B, Johnson, F, Boehm, B, Keiding, J, Raastam, J, Møller, M, Parkner, T, Jørgensen, C, Smedegaard, J, Christiansen, J, Mcdougall, A, Fitch, M, Nelson, G, Mueller, U, Saemann, A, Ishii, H, Iburi, T, Furuya, M, Yamagami, K, Sekine, O, Yamashiro, S, Ishibashi, R, Tsujii, S, Sauriol, L, Lescrauwaet, B, Heckmann, B, Helbig, C, Franke, I, Schiel, R, Oguzhan, B, Gursoy, N, Gutiérrez, E, García, P, Rokeya, B, Hossain, M, Ali, L, Ivanova, O, Gorbenko, N, Gladkich, A, Gorbenko, K, Blase, E, Nguyen, T, Su, G, Gao, H, Carr, E, Wintle, M, Fineman, M, Calara, F, Han, J, Aisporna, M, Zabala, E, Fehse, F, Trautmann, M, Halseth, A, Nauck, M, Kendall, D, Riddle, M, Zhuang, D, Buse, J, Henry, R, Linnebjerg, H, Kothare, P, De La Peña, A, Atkins, M, Bjerre Knudsen, L, Voss, P, Hompesch, M, Filipczak, R, Le, T, Zdravkovic, M, Gumprecht, J, Deacon, C, Plamboeck, A, Guivarch, P, Dreyfus, J, Mathi, S, Castaigne, J, Drucker, D, Kruger, D, Burrell, T, Gloster, M, Crean, J, Herrmann, K, Kovatchev, B, Cox, D, Mccall, A, Whitehouse, F, Chapman, I, Parker, B, Doran, S, Feinle bisset, C, Wishart, J, Lush, C, Mcintyre, S, Deckhut, D, Horowitz, M, El ouaghlidi, A, Rehring, E, Holmes, D, Sallas, W, He, Y, Watson, C, Ligueros saylan, M, Foley, J, Narayanan, S, Thomas, A, Shah, D, Gopalan, B, Vakkalanka, S, Arch, J, Ryskjær, J, Krarup, T, Madsbad, S, Vilsbøll, T, Ciani, S, Bardini, G, Pezzatini, A, Cappadona, A, Joergensen, M, Jensen holm, H, Kristensen, L, Kanstrup, A, Mckillop, A, Duffy, N, Lindsay, J, Bell, P, Hansen, B, Gronemann, S, Wilken, M, Herman, G, Zhao, P, Dietrich, B, Golor, G, Schrodter, A, Keymeulen, B, Lasseter, K, Kipnes, M, Hilliard, D, Tanen, M, De Smet, M, Van Dyck, K, Tanaka, W, Gottesdiener, K, Wagner, J, Hoffmann, T, S, V, Demuth, H, Paule, S, Myers, M, Nikolovski, B, Fujiwara, H, Hosokawa, M, Fukuda, K, Nishi, Y, Fujita, Y, Yamada, K, Ueda, N, Jones leone, A, Yu, T, Barilla, D, Ho, Y, Makrilakis, K, Panagiotakos, D, Dimosthenopoulos, C, Ioannidis, I, Chrysohoou, C, Pitsavos, C, Kuo, S, Levendal, R, Poonsatha, S, Jones, G, Fahey, R, Hoa, N, Norberg, Å, Liepinsh, E, Phan, D, Thuan, N, Jörnvall, H, Sillard, R, Tessari, P, Kiwanuka, E, Cristini, M, Zaramella, M, Enslen, M, Garcia rodenas, C, Yazawa, M, Imai, Y, Ohmura, E, Tsuchida, A, Matsuda, A, Hosaka, D, Horie, H, Ichita, M, Hisano, Y, Woodhead, S, Xu, W, Chen, X, Cavalot, F, Bonomo, K, Perna, P, Bacillo, E, Salacone, P, Gallo, M, Gaia, E, Vinik, A, Yu, D, Heise, M, Freed, M, Aguilera, E, Pellitero, S, Näf, S, Bendtzen, K, Nicoletti, F, Hahn, J, Bochnig, S, Koenig, H, Sporleder, B, Maisonneuve, P, Lowenfels, A, Kerner, W, Lankisch, P, Thai, A, Mohan, V, Khalid, B, Yeo, J, Gasiorowska, A, Talar wojnarowska, R, Malecka panas, E, Schindler, K, Rieger, A, Gmeinhart, B, Schlembacher, K, Merz, P, Ludvik, B, Müller, N, Rodriguez, F, Aas, A, Seljeflot, I, Huang, C, Biswas, N, Hashimoto, N, Kamatani, Y, Suzuki, Y, Yagui, K, Saito, Y, Iwai, R, Takahashi, H, Yoshida, S, Skowronski, M, Zozulinska, D, Juszczyk, J, Wierusz wysocka, B, Peterkova, V, Kuraeva, T, Scherbacheva, L, Andrianova, E, Maximova, V, Titovich, E, Danne, T, Bittner, C, Hanaire broutin, H, Schumicki, D, Souhami, E, Morrison, G, Purewal, T, Weston, P, Šmahelová, A, Rušavý, Z, Kožnarová, R, Loyková, V, Bělobrádková, J, Devries, J, Retnakaran, R, Hochman, J, Melki, V, Zinman, B, Corbi, S, Costanza, F, Fioriti, E, Cappa, M, Jaroň, M, Martínek, V, Piechatzek, R, Klaff, L, Prager, R, Robinson, A, Penfornis, A, Thomas, R, Selam, J, Sola gazagnes, A, Vitacolonna, E, Canonico, V, Fabietti, P, Iorio, M, Orsini Federici, M, Timi, A, Massi Benedetti, M, Sarti, E, Ashwell, S, Gebbie, J, Siebenhofer, A, Plank, J, Berghold, A, Horvath, K, Mrak, P, Jeitler, K, Pieber, T, Heller, S, Gottlieb, P, Paul, J, Chase, P, Menditto, L, Antuña, R, Grimaldi, A, Brun, J, Vialettes, B, Halimi, S, Dubroca, I, Blayo, A, Gómez peralta, F, Santos mazo, E, Payeras más, F, Abreu padín, C, Santos palacios, S, Salvador rodríguez, J, Burge, M, Schroeder, E, Witthaus, E, Johnston, P, Bradley, C, Kudva, Y, Jenkins, G, Pons, G, Quandt, L, Gebel, J, Vogelsang, D, Smith, S, Isley, W, Russell jones, D, Maier, C, Mustapic, D, Schuster, E, Luger, A, Eher, R, Koznarova, R, Rubesova, I, Pelikanova, T, Skibova, J, Sanz, F, Ampudia blasco, F, Gabaldon, J, Catala, M, Carmena, R, Heinemann, L, Kronshage, B, Ward, K, Sass, D, Essenpreis, M, Voelkel, D, Lodwig, V, Nguyen, M, Mondok, A, Friedrich, C, Caduff, A, Totonelli, A, Longhitano, S, Agrò, F, Edelman, S, Morrison, Z, Velazquez, F, Howard, S, Banks, R, Berger, B, Burian, P, Nilsson, K, Karlén, M, Rylander, E, Blonde, L, Freemantle, N, Ross, S, Duhot, D, Eggertsen, R, Hobbs, F, Martinez, L, Stridde, E, Skyler, J, Tusek, C, Stephan, J, Krasner, A, Landschulz, W, Sha, S, Bott, S, Bergenstal, R, Damgé, C, Ubrich, N, Kaltenbacher, M, Maincent, P, Wutte, A, Bock, G, Balent, B, Midtgaard, A, Rønn, B, Edgerton, D, Cherrington, A, Neal, D, Scott, M, Glass, D, Bowen, L, Wilson, W, Hobbs, C, Leach, C, Sivakumaran, S, Strack, T, De Meyts, P, Aladdin, H, Palsgaard, J, Theede, A, Sajid, W, Hinrichsen, J, Klaproth, B, Lademann, J, Østergaard, J, Andersen, A, Boss, A, Cheatham, W, Pfuetzner, A, Larbig, M, Forst, S, Abdollahnia, R, Grenningloh, M, Leatherdale, B, Bartley, E, Schwartz, S, Buchea, O, Hoss, U, Shah, R, Endo, T, Hata, S, Yamazaki, H, Hernandez Campos, S, Busciantella Ricci, N, Kaufman, F, Halvorson, M, Carpenter, S, Cooper, K, Mueller, J, Van Wasen, H, Brumberg, J, Rduch, K, Mertens, S, Reeß, F, Renz, H, Maran, A, Sparacino, G, Pavanini, A, Corazza, S, Crepaldi, M, Poscia, A, Acosta, D, Salcedo, D, Delgado, E, Novoa, J, Hawkins, F, Parramón, M, Mesa, J, Parhimovich, R, Darko, D, Odusanya, P, Pullen, F, Mukherjee, S, Child, D, Redkin, Y, Dreval, A, Bogomolov, V, Östgren, C, Grodzinsky, E, Lindström, K, Borgquist, L, Fegan, G, Hamliton, P, Mccrimmon, R, Evans, M, Fan, X, Ding, Y, Sherwin, R, Boomsma, F, Pramming, S, Fischer, B, Soydan, N, Eckhard, M, Saar, P, Kreuder, J, Linn, T, Holstein, A, Plaschke, A, Ptak, M, Egberts, E, El din, J, Kirchheiner, J, Hoashi, S, Khamis, A, Kilbane, M, Cannon, D, Gribben, A, Firth, R, Kinsley, B, Cranston, I, De Galan, B, De Mol, P, Wennekes, L, Due andersen, R, Lundkvist, J, Jönsson, L, Mukhopadhyay, B, Deans, K, Kesson, C, Jendrike, N, Buck, H, Abicht, A, Haug, C, Freckmann, G, Warren, R, Sommerfield, A, Allen, K, Deary, I, Frier, B, Høi hansen, T, Wu, A, Holtman, V, Tenberken, O, Maurer, H, Al zakwani, I, Bullano, M, Baron, J, Willey, V, Nattrass, M, Kurtzhals, P, Colding jorgensen, M, Massi benedetti, M, Murray, F, Lin, Z, Kølendorf, K, Prasek, M, Philotheou, A, Javashvili, L, Virsaladze, D, Kajaia, N, Raposo, J, Pratas, S, Fernandes, C, Valadas, C, Duarte, R, Gardete correia, L, Locatelli, M, Patera, I, Bottazzo, G, Hadjidakis, D, Mylonakis, A, Raptis, A, Papaefstathiou, A, Hedman, C, Frystyk, J, Fridell, K, Jönsson, A, Lindström, T, Saito, M, Eto, M, Kaku, K, Stotzka, M, Stein, G, Prince, M, Kulzer, B, Scholze, A, Hermanns, N, Kubiak, T, Starostina, E, Shavrikova, E, Furuhashi, N, Hirose, T, Kuroda, M, Kimura, M, Ishizawa, M, Sarui, H, Takeda, N, Furuta, T, Drewelow, S, Lindloh, C, Paddison, C, Faimalie, M, Flett, R, Micheletti, S, Perelli Cippo, P, Mantovani, L, Su, M, Trento, M, Bajardi, M, Passera, P, Miselli, V, Tomalino, M, Borgo, E, Cavallo, F, Porta, M, Miclea, S, Bogatean, M, Hancu, N, Leppert, K, Muller, U, Rittmeier, H, Mchorney, C, Myers, J, Reinecker, H, Meier, J, Gallwitz, B, Askenas, M, Vollmer, K, Schmidt, W, Kyrou, I, Souvatzoglou, E, Cseh, K, Baranyi, E, Kaszas, E, Szocs, A, Melczer, Z, Sikter, M, Szenthe, P, Palik, E, Hajos, P, Pogatsa, G, Winkler, G, Pardo, I, Barros filho, A, Jahan, S, Huq, F, Biswas, K, Chowdhury, T, Khan, A, Ritterath, C, Talai Rad, N, Siegmund, T, Heinze, T, Henrich, W, Siebert, G, Dudenhausen, J, Buhling, K, Kautzky willer, A, Mustafa, S, Winzer, C, Vukovich, T, Shaat, N, Ekelund, M, Lernmark, Å, Ivarsson, S, Zmudzinska, M, Bronisz, A, Pufal, M, Junik, R, Beran, D, Toledano, Y, Giveon, S, Kahan, E, Aycheh, S, Guttman, N, Jaffe, A, Alberti, H, Boudriga, N, Nabli, M, Jaiveer, S, Jaiveer, P, Shaikh, S, Gopinath, A, Morrissey, J, Patel, V, Lenz, M, Dvoynishnikova, O, Mayorov, A, Galstyan, G, Antsiferov, M, Dedov, I, Rybarczyk, M, Scalone, L, Palmer, A, Morgutti, M, Valentine, W, Renaudin, C, Roze, S, Morsanutto, A, Berto, P, Lopatriello, S, Voinovich, D, Gelisio, R, Brändie, M, Russ, W, Greiner, R, Rodríguez, J, Rubio Terrés, C, De Pablos, P, Smith, I, Morgan, C, Tsutskiridze, L, Haag, B, Delbuono, B, Silva, C, Fox, A, Padilla, V, Naraine, K, Cypryk, K, Szymczak, W, Szosland, K, Sobczak, M, Zawodniak szalapska, M, Lewinski, A, Schvarcz, E, Lindqvist, A, Stenninger, E, Östlund, I, Åman, J, Lapolla, A, Dalfrà, M, Di Benedetto, A, Dolci, M, Franzetti, I, Masotti, M, Napoli, A, Salietti, G, Santini, C, Tortul, C, Di Cianni, G, Popow, C, Waldhör, T, Horn, W, Biermann, E, Rihl, J, Riedl, M, Kastner, P, Kollmann, A, Pusch, W, Schreier, G, Hearnshaw, H, Lowe, P, Griffiths, F, Stapperfend, M, Baehring, T, Cosson, E, Benchimol, M, Carbillon, L, Pariès, J, Lormeau, B, Pharisien, I, Tourel, E, Uzan, M, Attali, J, Zabarovskaya, Z, Mulyarchik, O, Barsukov, A, Guseva, T, Begum, K, Haque, L, Bokor, A, Rigó, J, Garamvölgyi, Z, Pusztai, P, Somogyi, A, Hanson, U, Nyström, L, Blohmó, G, Ekbom schnell, A, Östman, J, Persson, B, Parretti, E, Cioni, R, Marzari, C, Masin, M, Scarselli, G, Mello, G, Seghieri, G, De Bellis, A, Anichini, R, Alviggi, L, Franconi, F, Breschi, C, Dworacka, M, Wender ożegowska, E, Winiarska, H, Macugowska, M, Zawiejska, A, Bobkiewicz kozłowska, T, Pietryga, M, Brązert, J, Bousboulas, S, Politakis, P, Papadimitriou, P, Lyu, R, Yin, D, Green, A, Kristensen, J, Rodríguez saldaña, J, Clark, C, Morales De Teresa, M, Escorza domínguez, A, Ortiz gress, A, Monroy mayorga, A, Mejía pedraza, B, Seeliger, S, Kaiser, J, Müller, E, Maxion bergemann, S, Bergemann, R, Goertz, A, Shearer, A, Bagust, A, Schoeffski, O, Shestakova, M, Balabolkin, M, Chugunova, L, Shamkhalova, M, Zaytseva, N, Naumenkova, I, Brevnova, N, Tsibina, L, Rosak, C, Petzoldt, R, Stammer, H, Dehmel, B, Seidel, D, Roth, W, Fennenkötter, U, Gottschall, V, Kanatsuka, A, Lauenborg, J, Jörgensen, T, Hornnes, P, Wagner, O, Zajdenverg, L, Halfoun, V, Oliveira, J, Lencioni, C, Volpe, L, Chatzianagnostou, K, Cuccuru, I, Ghio, A, Pardini, E, Salvadorini, M, Saltiki, A, Korakovouni, A, Stavrianos, H, Zapanti, E, Antsaklis, A, Pithova, P, Sporna, M, Bustani, R, Todd, D, Guerrero, R, Vázquez, M, Amaya, M, Dios, E, Quijada, D, García hernández, N, Astorga, R, Gandhi, R, Jayawarna, C, Fernando, D, Hill, R, Lloyd mostyn, R, Thomson, G, Rewers, A, Bothner, J, Klingensmith, G, Sysoyeva, O, Karlovich, N, Rankins, D, Wellard, M, Werther, G, Northam, E, Kordonouri, O, Haberland, H, Hauschild, M, Kapellen, T, Kraft, V, Wiemann, D, Lange, K, Witte, D, Laude, D, Dabire, H, Hadj Brahim, F, Papanas, N, Papatheodorou, K, Christakidis, D, Papazoglou, D, Giassakis, G, Piperidou, H, Monastiriotis, H, Maltezos, E, Barrett, C, Serghides, H, Tindali, H, Kelly, F, Chiheb, S, Chen, Q, Brahimi, M, Cynober, L, Delaporte, C, Scionti, L, Conti, M, Vermigli, C, Galimberti, G, Cazzetta, G, Bosi, E, Sugimoto, K, Shoji, M, Yasujima, M, Suda, T, Yagihashi, S, Zsengeller, Z, Charniauskaya, T, Abatan, O, Kimura, I, Tsuneki, H, Hara, S, Sasaki, K, Nangle, M, Gibson, T, Yorek, M, Hirooka, H, Stevens, M, Tarhzaoui, K, Cohen boulakia, F, Smith, G, Lestrade, R, Behar, A, Komori, H, Oi, K, Takahashi, D, Kunitou, T, Moroi, M, Philips, J, Marchand, M, Geronooz, I, Scheen, A, Gambardella, S, Ciampittiello, G, Bracaglia, D, Cicconetti, E, Gigli, F, Verri, C, Baroni, A, Frontoni, S, Szabó, M, Germán, M, Farkas, L, Szentendrei, D, Maiello, M, Mandica, S, Morganti, R, Menzinger, G, Bernardi, L, Aso, Y, Wakabayashi, S, Takebayashi, K, Takemura, Y, Inukai, T, Kalter leibovici, O, Lifshitz, A, Yerushalmy, Y, Stern, E, Ogawa, K, Nanjo, K, Kawamori, R, Katayama, S, Shirai, M, Fonseca, V, Seftel, A, Denne, J, Fredlund, P, Buvat, J, Schmitt, H, Van Ahlen, H, Varanese, L, Lips, J, Hoekstra, J, Banga, J, Legros, J, Lufuma, M, Bouter, K, Fan, L, Lu, J, Zheng, Y, Spruce, M, Jones, C, Coppini, D, Lavery, L, Holtz neiderer, K, Mohler, M, Wendel, C, Nixon, B, Jurado, J, Bataller, F, Dorca, A, Garcia, F, Brossa, N, Barnera, T, Pou Torelló, J, Bregovski, V, Karpova, I, Hedetoft, C, Rasmussen, A, Fabrin, J, Driver, V, Thoms, T, Jeffcoate, W, Monaghan, J, Game, F, Dalla Noce, S, Cimmino, M, Caruso, S, Manes, C, Mikoudi, K, Sossidou, E, Pigas, G, Karagianni, D, Skoutas, D, Fotiadis, S, Pruna, S, Eroshkin, I, Vasiljev, Y, Udovichenko, O, Udovichenko, A, Bondarenko, O, Dang, C, Prasad, Y, Anwar, R, Thomas, G, Lobmann, R, Motzkau, M, Pittasch, D, Lehnert, H, Piaggesi, A, Marsocci, A, Fanara, M, Rizzo, L, Palumbo, F, Campi, F, Tedeschi, A, Scatena, A, Goretti, C, Baicchi, U, Chipchase, S, Treece, K, Pound, N, Hill, N, Cyganek, K, Mirkiewicz sieradzka, B, Malecki, M, Wolkow, P, Skupien, J, Naskalska, A, Sieradzki, J, Tapp, R, Tonkin, A, Harper, A, Mccarty, D, Söderberg, S, Taylor, H, Chitson, P, Alberti, G, Sheetz, M, Aiello, L, Davis, M, Milton, R, Arora, V, Hu, K, Girach, A, Vignati, L, Tyrberg, M, Melander, A, Lindblad, U, Giannarelli, R, Coppelli, A, Sartini, M, Aragona, M, Fletcher, E, Ninkovic, S, Foster, L, Jones, D, De Gooyer, T, Stitt, A, Vingrys, A, Wilkinson berka, J, Lewandowska, A, Randeva, H, Komorowski, J, Lewandowski, K, Jurowski, P, Sankar, S, Gos, R, Kowluru, R, Odenbach, S, Shinn, S, Agardh, C, Hultberg, B, Segura, R, Fonollosa, A, Berrone, E, Beltramo, E, Solimine, C, Ubertalli, A, Islam, N, Esteve, E, Fernandez, M, Recas, I, Mauri, S, Biarnes, F, Junca, E, Fernádez real, J, Rössner, S, Stenlof, K, Levy, B, Perry, B, Fitchet, M, Chrysos, G, Kamaratos, A, Lepeniotis, G, Kokkoris, S, Varytimiadis, K, Stasini, F, Mikros, S, Gianneli, D, Tryfinopoulou, K, Melidonis, A, Nikolopoulou, C, Harley, K, Ryder, R, De, P, Vannieuwenhoven, F, Rossing, K, Oliver, N, Goldschmeding, R, Jacobsen, P, Tan, F, Liew, S, Mukherjee, J, Lim, P, Fröjdö, S, Sjölind, L, Parkkonen, M, Mäkinen, V, Tikellis, C, Nieuwenhoven, F, Macisaac, R, Tsalamandris, C, Mcneil, K, Panaiotopoulos, S, Smith, T, Ho, M, Matthews, P, Jerums, G, Hut, H, Van Den Meiracker, A, Nakhjavani, M, Behjati, J, Esteghamati, A, Esfahanian, F, Aghamohamadzadeh, N, Abbasi, M, Kohnert, K, Zander, E, Krabbe, S, Stehouwer, C, Schalkwijk, C, Krarup Hansen, T, Teppo, A, Ebeling, P, Abdella, N, Mojiminiyi, O, Al Dahi, W, Al Mohammedi, H, Al Jebely, S, Neugebauer baba, S, Baba, T, Ohashi, H, Nakajima, S, Hesselmann, C, Watanabe, T, Nargis, M, Zaid, R, Voronko, O, Tchugunova, L, Vikulova, O, Nosikov, V, Liu, L, Zheng, T, Li, M, Zhang, R, Xiang, K, Hadjadj, S, Jeunemaitre, X, Vervoort, G, Veldman, B, Berden, J, Wetzels, J, Singh, B, Holland, M, Baskar, V, Oh, J, Seo, J, Choi, K, Baik, S, Choi, D, Kim, N, Matsumoto, S, Suetsugu, M, Matsutomo, R, Pisarczyk wiza, D, Banaszak, A, Wysocki, H, Usui, H, Shikata, K, Okada, S, Ogawa, D, Yozai, K, Kido, Y, Nagase, R, Ohga, S, Tone, A, Sasaki, M, Wada, J, Unno, Y, Horiuchi, S, Mclennan, S, Kamarinos, M, Waltham, M, Dy, V, Yue, D, Zdychova, J, Komers, R, Cresci, B, Giannini, S, Manuelli, C, Giunti, S, Pinach, S, Ianni Palarchio, A, Arnaldi, L, Vittone, F, Camussi, G, Cavallo Perin, P, Gruden, G, Marshall, S, Jones, S, White, K, Brizzi, M, Dentelli, P, Rosso, A, Calvi, C, Gambino, R, Cassader, M, Salvidio, G, Deferrari, G, Pegoraro, L, Pagano, G, Cavallo perin, P, Oates, R, Ellery, C, Beebe, D, Coutcher, J, Qian, Y, Lowe, V, Appleton, T, Raunig, D, O'Neil, S, Mylari, B, Amazonas, R, Fujita, A, Doi, A, Matsuno, S, Okamoto, K, Matsumoto, E, Furuta, H, Nishi, M, Tsuno, T, Taniguchi, H, Bessho, H, Wasén, E, Isoaho, R, Mattila, K, Vahlberg, T, Kivelä, S, Irjala, K, Rigalleau, V, Lasseur, C, Perlemoine, C, Barthes, N, Raffaitin, C, Chauveau, P, Combe, C, Baillet blanco, L, Beauvieux, M, Gin, H, Heinrich, S, Steiner, T, Ott, U, Holdass, H, Fellström, B, Jardine, A, Staffler, B, Logan, J, Gimpelewicz, C, Stanciu, C, Pena, C, Serafinceanu, C, González posada, J, Hernández, D, Pérez tamajó, L, Ló, A, Herná Alarcó, M, Meneses, M, Barsotti, M, Rizzo, G, Schmauss, S, Havrdova, T, Saudek, F, Boucek, P, Adamec, M, Invitti, C, Gilardini, L, Parati, G, Mazzilli, G, Pontiggia, B, Sartorio, A, Lutgers, H, Groenier, K, Zasadzinska, G, Saryusz wolska, M, Kurktschiev, D, Majdrakova, I, Varbanova, T, Todorova, B, Bajo martinez, A, Bernal, E, Sanchez, O, Ugalde canitrot, A, Sanchez largo, E, Coca robinot, D, Fabregate, R, Calbacho, M, Marquez, J, Saban ruiz, J, Penesova, A, Cizmarova, E, Blazicek, P, De Jongh, R, Serné, E, Ijzerman, R, De Vries, G, Andersen, N, Knudsen, S, Helleberg, K, Mogensen, C, Waluś, M, Idzior waluś, B, Sztefko, K, Cieślik, G, Fedak, D, Wozniakiewicz, E, Lin, S, Guo, M, Lin, C, Liu, X, Francisco, M, Rodriguez rosas, H, Peiró martinez, I, Macías batista, A, Harte, A, Rodriguez cuenca, S, Valsamakis, G, Chetty, R, Anderson, L, Roca, P, Matyka, K, Lasalle, J, Hershon, K, Berman, L, Gibson, E, Gillen, D, Maroni, J, Simmons, D, Hiukka, A, Forder, P, Leinonen, E, Hilden, H, Fruchart, J, Keech, A, Farnier, M, Freeman, M, Macdonell, G, Perevozskaya, I, Mitchel, Y, Gumbiner, B, Didangelos, T, Athyros, V, Mikhailidis, D, Papageorgiou, A, Bouloukos, V, Pehlivanidis, A, Symeonidis, A, Elisaf, M, Mckenney, J, Insull, W, Lewin, A, Maccubbin, D, Kush, D, Schuster, H, Barter, P, Stender, S, Bonnet, J, Morrell, J, Watkins, C, Kallend, D, Stalenhoef, A, Ballantyne, C, Murin, J, Tonstad, S, Rose, H, Wilpshaar, W, Jenkins, A, Karschimkus, C, Dragicevic, G, Rowley, K, Wolthers, T, Best, J, Voet, B, Murdoch, S, Marcovina, S, Brunzell, J, Caparevic, Z, Kostic, N, Ilic, S, Sartore, G, Piarulli, F, Cantaro, S, Reitano, R, Fiore, C, Marin, R, Bassan, S, Manzato, E, Fedele, D, Solini, A, Santini, E, Thornalley, P, Babaei jadidi, R, Karachalias, N, Kupich, C, Ahmed, N, Fowler, A, Baker, A, Starczynski, J, O'Hare, P, Szepietowska, B, Szelachowska, M, Puch, U, Glebocka, A, Quinn, D, Mcternan, C, Bonser, R, Idzior walus, B, Woźniakiewicz, E, Dimitriou, K, Apostolou, O, Kontela, E, Devangelio, E, Gould, E, Serri, O, Roussin, A, Buithieu, J, Mamputu, J, Renier, G, Giordanetti, S, De Amici, E, Poggi, G, Turpini, C, Fratino, P, Garzaniti, A, Banu, I, Paries, J, Roman, G, Negrean, M, Bala, C, Nita, C, Kistorp, C, Gustafsson, F, Chong, A, Lip, G, Galatius, S, Ari, N, Sahilli, M, Ceylan isık, A, Ozansoy, G, Karasu yilmaz, C, Matteucci, E, Rosada, J, Pallini, M, Evangelista, I, Cassetti, G, Giusti, C, Giampietro, O, Capaldo, B, Galderisi, M, Cicala, S, Turco, A, Imbroinise, A, Nosso, G, D'Errico, A, De Divitiis, O, Klimontov, V, Korolyova, E, Jeltova, L, Bondar, I, Tarkun, I, Arslan, B, Canturk, Z, Tarkun, P, Agacdiken, A, Komsuoglu, B, Méneveau, N, Pierre justin, E, Alsayed, M, Sabbah, R, Paulin, S, Marcu, S, Tauveron, I, Zimmermann, C, Schiele, F, Seronde, M, Vautrin, P, Lusson, J, Thieblot, P, Bernard, Y, Mistry, A, Pye, M, Peovska, I, Maksimovic Pavlovic, J, Vavlukis, M, Pop Gorceva, D, Bosevski, M, Scognamiglio, R, Negut, C, De Kreutzenberg, S, Madonna, R, De Caterina, R, Willerson, J, Geng, Y, Vahsen, S, Ledwig, D, Ramrath, S, Frantz, S, Schmidt, I, Calvillo, L, Dienesch, C, Elbing, I, Bischoff, H, Ertl, G, Bauersachs, J, Davydov, A, Mkrtum'Yan, A, Baranova, L, Ikeda, Y, Suehiro, T, Osaki, F, Ota, K, Arii, K, Kumon, Y, Hashimoto, K, Doney, A, Morris, A, Palmer, C, Byun, S, Doo, H, Pagnin, E, Calo, L, Fadini, G, Kubaszek, A, Chai, S, Chai, Q, Rasmussen, L, Ledet, T, Wogensen, L, Lengyel, C, Varró, A, Virág, L, Magyar, J, Bíró, T, Jost, N, Skoumal, R, Nánási, P, Tóth, M, Horkay, F, Papp, J, Zacharopoulou, O, Athanaselis, S, Tsokos, N, Doupis, J, Psallas, M, Cokkinos, D, Pavlatos, S, Liatis, S, Akhobadze, T, Dzneladze, L, Samarguliani, I, Taskiran, M, Rasmussen, V, Jensen, G, Fisher, A, Petrovsky, N, Srikusalanukul, W, Budge, M, Trifunovic zamaklar, D, Zivkovic, M, Jelic, V, Vukomanovic, G, Ristic, A, Seferovic, P, Costa, J, Duarte, S, Manley, S, Sailesh, S, Venkataraman, A, Haider, Y, Groza, I, Oprean, M, Ardelean, A, Morosanu, A, Darkow, T, Vanderplas, A, Mamas, M, Mcelduff, P, Burns, J, Edwards, R, Fitchet, A, Young, R, Gibson, J, Lichiardopol, R, Niculescu, N, Totora, A, Pencea, C, Tomescu, I, Cinteza, M, Manicardi, V, Coscelli, C, Navazio, A, Catellani, E, Michelini, M, Dall'Asta, D, Guberti, A, Piazza, A, Gasparini, E, Pantaleoni, M, Guiducci, U, Manari, A, Sejil, S, Janand delenne, B, Avierinos, J, Habib, G, Labastie, N, Vague, P, Lassmann vague, V, Luźniak, P, Tatoń, J, Wojciechowska Luźniak, A, Zairis, M, Lyras, A, Patsourakos, N, Tsirimbis, V, Foussas, S, Lupón, J, Urrutia, A, Herreros, J, González, B, Coll, R, Altimir, S, Prats, M, Valle, V, Abreu padí, C, Rábago, G, Ivanova, L, Brasacchio, D, Harno, E, Keenan, A, Li, H, Lu, Z, Ke, L, Liu, H, Jeong, I, Chae, M, Choi, M, Yoo, H, Kim, C, Yun, M, Na, M, Kang, Y, Kong, O, Son, S, Kim, I, Tanaka, N, Hosoi, M, Matsuyama, Y, Fukumoto, M, Yamakita, T, Yoshioka, K, Ishii, T, Sato, T, Fujii, S, Aoki, T, Shibata, T, Mizutani, N, Suzuki, J, Fowelin, J, Samuelsson, P, Brandrup wogsen, G, Okumura, K, Tokmakova, A, Staroverova, D, Antcieferov, M, Shutichina, I, Kuntchevich, G, Vriesendorp, T, Morélis, Q, Legemate, D, Schaper, F, Mainas, E, Gkioulmpasanis, I, Panagiotou, I, Vassilikos, G, Skorda, L, Sidira, M, Christoforidou, M, Alaveras, A, Artikis, V, Evdemon, E, Lechleitner, M, Koch, T, Ebenbichler, C, Sturm, W, Moretti, L, Moruzzo, D, Boldrini, E, Pandolfo, C, Kameyama, M, Iwasa, R, Cho, M, Nam, J, Huh, K, Kaplar, M, Paragh, G, Erdei, A, Csongradi, E, Garai, I, Varga, J, Galuska, L, Udvardy, M, Higa, M, Kaneko, Y, Hiroi, N, Koziarska, D, Nowacki, P, Majkowska, L, Luzniak, P, Wojciechowska luźniak, A, Tushuizen, M, Nieuwland, R, Snoeck, D, Sturk, A, Diamant, M, Aguiar, L, Bahia, L, Villela, N, Laflor, C, Conde, C, Bottino, D, Dorigo, D, Bouskela, E, Pu, S, Luo, Z, Lam, K, Dan, Q, Xu, A, Shen, J, Cheng, K, Xu, J, Thamer, C, Stefan, N, Haap, M, Heller, E, Tschritter, O, De Prado, A, Ortiz, A, Ybarra, J, Gich, I, Pou, J, Ehren, M, Roggenland, D, Reinsen, B, Klein, H, Rittig, K, Stock, J, Kocher, B, Balletshofer, B, Shon, H, Chung, D, Nakatani, Y, Matsuhisa, M, Kaneto, H, Hatazaki, M, Yoshiuchi, K, Katakami, N, Kawamori, D, Ohtoshi, K, Sakamoto, K, Matsuoka, T, Ozawa, K, Ogawa, S, Hori, M, Yamasaki, Y, Zitouni, K, Harry, D, Nourooz zadeh, J, Earle, K, Olesen, P, Franco, L, Corvaja, C, Semplicini, A, Ceylan işık, A, Arı, N, Rösen, P, Lee, I, Park, K, Jung, E, Shin, D, Jo, S, Obuobie, K, Prakash, P, Hanna, F, Lazarus, J, Varadhan, L, Gurushankar, J, James, D, Sheikh, S, Gaede, P, Zou, D, Vilarrasa, N, Perez maraver, M, Mena, E, Perez, D, Setti, G, Buckingham, R, Urbančič, V, Stefanovska, A, Bernjak, A, Ažman juvan, K, Kocijančič, A, Glowania, A, Filters, T, Fosmark, D, Torjesen, P, Kilhovd, B, Berg, T, Sandvik, L, Hanssen, K, Mentink, C, Donchenko, G, Stepanenko, S, Maingrette, F, Deng, H, Lindenmair, A, Freudenthaler, A, Baumgartner parzer, S, Nizheradze, K, Khoruzhenko, A, Tronko, N, Sheu, W, Ou, H, Shen, H, Lin, T, Wu, H, Yang, C, Mogylnytska, L, Schmoelzer, I, Davies, J, Band, M, Struthers, A, Prázný, M, Škrha, J, Kasalová, Z, Neelotpol, S, Jahan, P, Kauschke, S, Harrop, C, Schäfer, A, Widder, J, Eigenthaler, M, Walter, U, Uchimura, I, Ikebukuro, M, Kaibara, M, Hirata, M, Helal, R, Pervin, F, Yang, X, Jansson, P, Nagaev, I, Jack, M, Carvalho, E, Sunnerhagen, K, Cam, M, Cushman, S, Smith, U, Creely, S, Farmer, J, Gustafson, B, Kusminski, C, Krusinova, E, Wohl, P, Klementova, M, Lanska, V, Mcdougall, C, Kelly, I, Abbas, Z, Lutale, J, Archibald, L, Karunajeewa, H, Stingemore, N, Stuccio, G, Mcgechie, D, Muller, L, Hak, E, Goudzwaard, W, Montorsi, F, Homering, M, Sprenger, K, Goldstein, I, Asnaghi, V, Ferrari, G, Rastaldi, M, Gabellini, D, Dell'Antonio, G, Maestroni, A, Ruggieri, D, Luzi, L, Piemonti, L, Zerbini, G, Anafaroglu, I, Tutuncu, N, Sultana, M, Siddiqua, N, Iwasaki, T, Nakajima, A, Yoneda, M, Mukasa, K, Tanaka, S, and Sekihara, H
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0303 health sciences ,medicine.medical_specialty ,business.industry ,EASD ,Endocrinology, Diabetes and Metabolism ,Human physiology ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Family medicine ,Internal Medicine ,Medicine ,business ,030217 neurology & neurosurgery ,030304 developmental biology - Published
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