1. AML with Renal Infiltration Manifesting as Acute Renal Failure, Diagnosed with FDG-PET CT Scan: Case Report
- Author
-
Nityanand S, Gupta A, Chauhan P, Ora M, and Agrawal S
- Subjects
medicine.medical_specialty ,business.industry ,hemic and lymphatic diseases ,medicine ,Fdg pet ct ,General Medicine ,Radiology ,medicine.disease ,business ,Infiltration (medical) - Abstract
Extramedullary disease in acute myeloid leukemia is a known phenomenon with reported incidence of 2.5-9.1 %. However, acute kidney injury due to direct infiltration of malignant cells is reported in only 1% cases of acute leukemia. We report a case of acute myeloid leukemia who developed acute kidney failure at presentation, was diagnosed with renal and pancreatic infiltration by FDG-PET scan and was treated successfully with hypomethylating agent and venetoclax. PET-CT scan can be a non-invasive modality for diagnosing extramedullary disease in acute myeloid leukemia and monitoring of response to therapy in these cases. Early initiation of anti-leukemia therapy in our case lead to complete metabolic response with normalization of the renal functions.
- Published
- 2021