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Introduction: The use of chest Computed Tomography (CT) scans has significantly increased in recent times, and it is also considered the preferred investigation method in various cases, including occult pneumothorax and interstitial lung diseases. Aim: To assess the relationship between chest CT scan findings/outcomes, clinicians’ expectations, and their influence on treatment outcomes. Materials and Methods: The present retrospective analytical observational study was conducted in the Department of Radiodiagnosis and Respiratory Medicine at a tertiary-level hospital, Adesh Medical College and Hospital, Kurukshetra, Haryana, India. The findings of the selected chest CT scans were classified as normal, incidental, or pathological. The response of the consulting physicians to these scans was divided into three grades: highly expected, moderately expected, and unexpected. The impact of these scans on patients’ treatment was divided into three categories: major, minor, and none. The collected data were analysed using the Statistical Package for Social Sciences (SPSS) version 28.0, and the Chi-square test was used to assess the association between different variables. Results: The mean age of study participants was approximately 58±15 years. Out of the total 74 scans (each belonging to a different individual), the findings of the chest CT scans revealed that 59 (79.7%) scans were pathological, 11 (14.9%) were incidental, and only 4 (5.4%) were normal. The outcomes of these scans were highly expected in 42 (56.7%) cases, moderately expected in 25 (33.8%), and unexpected in 7 (9.5%). These scans had a major impact on the patient’s treatment course in 28 (37.8%) cases, minor impact in 40 (54%), and no influence in 6 (8.1%) cases. The Chi-square test showed a significant association between chest CT scan outcomes and clinicians’ expectations, chest CT scan outcomes and their influence on treatment, as well as clinicians’ expectations and the effect of scans on treatment. The p-value

Tuberculosis (TB) is prevalent throughout the world and is a major public health problem in most developing countries. In India, standardised and Directly Observed Treatment (DOT) under National Tuberculosis Elimination Programme (NTEP) is being recommended currently for drug-sensitive pulmonary TB. TB being a major health issue in developing nations like India, causes enormous death and morbidity every year. Anti-Tuberculosis Treatment (ATT) given for TB has been highly effective in fighting the disease and is generally well tolerated, with few minor side-effects. We report a 76-year-old male who was diagnosed with pulmonary TB and was on first-line four-drug anti-tubercular therapy ATT since seven days. He presented to the emergency department with loss of weight and appetite, chest tightness and vomiting. Liver Function Tests (LFT) was deranged, suggesting ATT-induced hepatitis. After normalisation of LFT, rifampicin reintroduction was initiated. Complete Blood Count (CBC) revealed pancytopenia. In bone marrow biopsy, normoblastic maturation with few micronormoblasts and megaloblast picture was seen that did not reveal any granuloma, thereby ruling out the presence of Mycobacterium tuberculosis (MTB). Iron profile and vitamin B12 levels were within normal limits. Rifampicin-induced pancytopenia is rare but its possibility should always be kept in mind while treating with ATT.