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4 results on '"N. Almqvist"'

1. Prevention and intervention of allergy (PP-083)

Author

C. H. Huang, B. Chiang, E. Adam, Z. N. Chang, M. D. Leech, T. Ho, A. Svensson, M. Kawano, W. Chou, M. Raymond, M. Terashima, Z. Goseva, L. Shi, K. Ruxrungtham, J. Youn, S. Raskovic, M. Sarfati, S. Piboonpocanun, B. Kaeva, K. Ogasawara, V. Reynders, S. Kuo, B. Chua, S. Wong, S. Ling, T. Honda, E. Muraille, M. Shimada, S. Sirivichayakul, R. Valenta, K. Eriksson, P. Pulsawat, M. B. Ghafourian, C. Hung, F. Huang, M. Kuo, K. Katsuoka, Z. Juranic, Y. Chang, Z. S. Arsovski, C. Bouillot, M. L. Chen, S. Habu, C. Wu, S. Nutten, H. J. Peng, S. Narumiya, M. Nakayama, Y. H. Hong, L. Delbrassine, L. Jankovic, S. M. Anderton, L. Garcia, F. Gantner, A. J. Melendez, A. Mailleux, V. Niederberger-Leppin, Y. Matsumura, S. Kim, S. Ambu, M. Hsieh, P. R. Babu, A. Konic-Ristic, H. Saidian, J. Wang, J. Komotori, I. C. Kuo, N. Almqvist, M. Rubio, K. Kabashima, P. M. Fitch, J. Schmied, K. Marth, K. Lee, S. Onuma, P. L. Shek, B. F. Lin, I. Ursu Magdu, K. Erb, I. Besu, H. Huang, B. Wilkie, J. Schwarze, Y. Amoh, D. M. Kemeny, J. Tan, H. Wen, S. C. Duncker, K. J. Mackenzie, S. Buranapraditkun, M. Gavrilovski, Y. Tsubota, Y. Ye, Z. Zizak, M. E. Azemi, K. Y. Chua, T. R. Jan, C. Lupinek, C. Huang, Y. Ogawa, Y. Lin, J. Mak, A. Mercenier, M. Düchs, S. Niiyama, K. Wong, C. F. Huang, T. Fujita, A. Jacquet, D. Philippe, H. Chou, and H. Tamauchi

Subjects
medicine.medical_specialty, Allergy, business.industry, Family medicine, Intervention (counseling), Immunology, medicine, Immunology and Allergy, General Medicine, business, medicine.disease
Published
2010
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2. Mucosal immunity: homeostasis (PP-064)

Author

Y. Ueda, P. N. Boyaka, Zuzana Jiraskova Zakostelska, K. Inagaki-Ohara, C. E. Martin, S. Hansen, K. Fujihashi, A. Lo, I. Yang, E. Umemoto, N. Yoshida, C. D. Surh, D. Kim, Y. Iwasaki, K. S. Schluns, D. D. Chaplin, R. Kobayashi, S. Takaki, K. Lee, M. Iseki, J. Tomala, S. Kim, H. Kayama, Y. Saito, M. Kovar, R. S. Gilbert, Lucia Hrncirova, M. Hou, M. Miyasaka, T. Iwase, U. Gehrmann, A. Yoshimura, Y. Lai, H. Katayama, D. A. Peterson, Y. Iwakura, Tomas Hrncir, K. Takatsu, N. Almqvist, S. Lindgren, D. Papazian, Y. Minokoshi, G. Matsuzaki, M. Yamasaki, R. Hamamichi, T. Vorup-Jensen, S. Kato, Y. Jang, T. Chhoden, N. Marsteller, Helena Tlaskalova-Hogenova, N. Liao, K. Takeda, K. Skjoedt, Klara Klimesova, Y. Fukuyama, M. Fujimoto, Miloslav Kverka, N. Verjan Garcia, T. Matozaki, K. Lund, S. Huang, M. Murakami, H. Yang-Yen, P. A. Würtzen, L. J. Ma, C. Nielsen, E. Telemo, M. Arge, K. Komiyama, M. Jang, and J. Y. Lee

Subjects
business.industry, Immunology, Immunology and Allergy, Medicine, General Medicine, business, Mucosal immunity, Homeostasis
Published
2010
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3. Exosomes - nanovesicles with possible roles in allergic inflammation

Author

Riitta Lahesmaa, N. Almqvist, Esbjörn Telemo, Annika Scheynius, Charlotte Admyre, Jan Lötvall, and Susanne Gabrielsson

Subjects
Inflammation, Endosome, business.industry, T cell, Immunology, Antigen presentation, Cytoplasmic Vesicles, medicine.disease_cause, Exosome, Microvesicles, Allergic inflammation, Cell membrane, medicine.anatomical_structure, Allergic response, medicine, Hypersensitivity, Immune Tolerance, Immunology and Allergy, Animals, Humans, business
Abstract

Exosomes are nano-sized membrane vesicles which are released extracellularly after fusion of multivesicular endosomes with the cell membrane. Despite their characteristic composition of proteins compared to the cell membrane, no exosome-specific molecule has so far been characterized. Exosomes are found in bronchoalveolar lavage (BAL), urine, serum and breast milk, and are released from several cells implicated in allergy including mast cells, dendritic cells (DC), T cells and epithelial cells. Antigen-loaded exosomes have been shown to be highly immunogenic and we propose that exosomes could be a modulating factor in allergic responses. Allergen-presenting exosomes could transport allergen and stimulate allergen-specific T cells, and possibly also biasing T cell responses depending on the molecules present on the exosome surface. Furthermore, exosomes from mast cells, highly active in allergic reactions, have been found to induce DC maturation and also to be able to transport functional RNA to recipient cells, suggesting a new pathway for cell communication. Reversely, tolerizing exosomes e.g. tolerosomes, from gut or breast milk, could block an allergic response or prevent allergy development. A better understanding of the role of exosomes in allergies could make us understand how allergy can be prevented or lead to the development of more efficient treatments.

Published
2008

4. Analysis of Global Protein Content in Mast Cell Exosomes

Author

Jan Lötvall, Hadi Valadi, N. Almqvist, Apostolos Bossios, Karin M. Ekström, and Margareta Sjöstrand

Subjects
Protein content, medicine.anatomical_structure, Chemistry, Immunology, medicine, Immunology and Allergy, Mast cell, Microvesicles, Cell biology
Published
2006
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