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Introduction: Breast carcinoma demands attention as it causes high morbidity and mortality. It is important to recognise benign lesions to distinguish them from in situ and invasive breast cancer and to assess a patient’s risk of developing breast cancer, so that the most appropriate treatment modality for each case can be established. The p63 has been characterised as a reliable marker of myoepithelial cells of lactiferous duct. It is exclusively expressed in myoepithelial cells of normal breast tissue. Hence, p63 can be of great help in the differential diagnosis involving benign lesions. Also, p63 may aid in distinguishing benign from malignant lesions. Aim: To study the Immunohistochemistry (IHC) expression of p63 in benign and malignant breast lesions. Materials and Methods: The prospective study was conducted on 76 breast specimens for a period of one year, from 1st December 2018 to 30th November 2019 in the Department of Pathology, Bhagat Phool Singh, Government Medical College for Women, Khanpur Kalan, Sonepat, Haryana, India. IHC assessment for p63 nuclear protein was performed. The intensity of p63 expression was evaluated as continuous positive, discontinuous positive and negative. The extent was scored on the basis of percentage of positive cells and assigned a score of negative (0%), 1 (

Background and objectives: Recurrent pterygium is an important ocular problem in our country. There are different modalities of treatment for recurrent pterygium. The present study was undertaken to determine the effect of intraoperative mitomycin C along with conjunctival auto graft to prevent recurrence of pterygium. Methods: Patients with recurrent pterygium attending a tertiary care hospital in Dhaka from January 2013 to June 2015 were included in the study. Cases were randomized into two groups. Group 1 had pterygium surgery with conjunctival auto graft and Group 2 had auto graft and intraoperative mitomycin C (0.02%). All cases were followed up for one year to assess recurrence of pterygium. Results: A total of 54 recurrent pterygia cases were included in the study. The age of study population was 25 to 65 years. The recurrence rate of pterygium after 12 months was 77.7% in group 1 and none in group 2. No major postoperative complication was observed. Conclusion: The study demonstrated that the use of intraoperative mitomycin C along with conjunctival auto graft had significant effect in preventing the recurrence of pterygium. IMC J Med Sci 2016; 10(2): 49-52

Background and objectives: Suture or glue has been used to secure the conjunctival auto graft after excision of the pterygium. Recently, auto grafting using patient’s own blood as a bioadhesive to secure the graft in position has been described by several authors. Therefore, the present study was undertaken to determine the outcome of excision of pterygium and sutureless conjunctival auto graft using patients’ own blood as a bioadhesive. Methods: Patients with primary and recurrent pterygium attending the Department of Ophthalmology of Bangladesh Institute of Research, Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) hospital from March 2014 to July 2015 were included in the study. Pterygium was excised and conjunctival auto graft was applied. Grafts were secured to the pterygium excision area with auto blood fibrin clot. All patients were examined after 48 hr and followed for 1, 4 and 12 weeks for graft dislodgement, sub-conjunctival hemorrhage, graft recession, graft edema and recurrence of pterygium. Results: A total of 35 primary and 2 recurrent pterygium cases were included in the study. The mean operation time was 15±1 minutes. Out of 37 eyes 5 (13.5%) had subconjunctival hemorrhage and 2 (5.4%) had graft recession and edema after 48hrs of operation. At 3 months follow up, 2 cases (5.4%) of graft recession and no case of recurrence of pterygium was found. Conclusion: Pterygium excision and conjunctival auto graft without sutures appears to be an effective treatment modality for primary and recurrent pterygium with no additional cost. IMC J Med Sci 2016; 10(2): 36-38