1. QT Dispersion Correlates with Systolic Rather than Diastolic Parameters in Patients Receiving Anthracycline Treatment
- Author
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Takahisa Yamane, Noboru Okamoto, Takeo Hayashi, Kei Tsumura, Hirohisa Nakamae, Kensuke Ohta, Mutsuo Kaneko, Ikuko Saito, Mika Akahori, Yoshio Ichihara, Yoshiki Terada, and Masayuki Hino
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Anthracycline ,Systole ,Diastole ,Sensitivity and Specificity ,Automation ,Electrocardiography ,Heart Conduction System ,Reference Values ,Internal medicine ,Internal Medicine ,medicine ,Humans ,Anthracyclines ,In patient ,Diastolic function ,Aged ,Probability ,Analysis of Variance ,Ejection fraction ,Dose-Response Relationship, Drug ,medicine.diagnostic_test ,business.industry ,Corrected qt ,General Medicine ,Middle Aged ,Echocardiography, Doppler ,Long QT Syndrome ,Case-Control Studies ,Hematologic Neoplasms ,Qt dispersion ,Heart Function Tests ,Cardiology ,Female ,business - Abstract
Objective The aim of this study was to investigate the relation of QT dispersion to left ventricular (LV) systolic and diastolic function in patients undergoing anthracycline therapy. Methods We used echocardiography to evaluate LV systolic and diastolic function and electrocardiography to evaluate QT dispersion and corrected QT dispersion (QTcD) in patients with hematological diseases, who received anthracycline therapy. Patients Seventy-two patients with hematological diseases who were receiving anthracycline treatment were enrolled in the present study. Results LV end-diastolic diameter or LV end-systolic diameter had a significant positive correlation to QTcD (r=0.35, p
- Published
- 2004