1. Abstract P155: Phenotyping The Association Between Nocturia And Hypertension: A Systematic Review And Meta-analysis
- Author
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Jason Lazar, Daniel J. Cao, Michael Vaysblat, Jeffrey P. Weiss, Syed N. Rahman, Matthew Moy, Thomas F. Monaghan, and Viktor X. Flores
- Subjects
medicine.medical_specialty ,Blood pressure ,business.industry ,Vascular disease ,Internal medicine ,Meta-analysis ,Internal Medicine ,medicine ,Nocturia ,medicine.symptom ,business ,medicine.disease - Abstract
Introduction: The association between nocturia and hypertension has been widely reported, yet remains poorly characterized, precluding a more refined understanding of blood pressure as it relates to the clinical urology setting. We synthesized current evidence on the relationship between nocturia and hypertension as a function of nocturia severity, age, sex, race, and diuretic use. Methods: We searched PubMed, EMBASE, and Cochrane databases for studies published up to May 2020. Random effects meta-analyses were performed to identify the pooled odds ratio (OR) for nocturia given the presence of hypertension. Meta-regression and subgroup analyses were performed to identify differences across demographic factors. We applied the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies to evaluate the quality of evidence. Results: Of 1530 identified studies, 23 met the criteria for inclusion. The overall pooled OR for the association of hypertension with nocturia was 1.26 (95% CI 1.22-1.29, p Conclusions: There exists an increased odds of nocturia in hypertensive individuals. This association is stronger following a higher nocturia cutoff, in females, and in some racial subgroups, but unrelated to age and diuretic utilization.
- Published
- 2020
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