Search

Your search keyword '"Lo Cascio, M."' showing total 4 results
Start Over Author "Lo Cascio, M." Topic medicine
4 results on '"Lo Cascio, M."'

1. Confirmatory factor analysis of the Patient Assessment of Constipation-Symptoms (PAC-SYM) among patients with chronic constipation

Author

Neri L, Conway PM, Basilisco G, Altomare DF, Annese V, Badiali D, Bassotti G, Battaglia E, Bazzocchi G, Bellini M, Bendia E, Benini L, Biscaglia G, Biviano I, Bocchini R, Bonfrate L, Bonventre S, Bossa F, Brandimarte G, Cannizzaro R, Cicala M, Cipolletta L, Clara V, Cogliandro R, Comandini G, Corazziari E, Crotta S, CUOMO, ROSARIO, D'Alba L, De Giorgi F, Del Piano M, Di Fonzo M, Di Mario Francesco, Di Stefano M, D'Onofrio V, Efthymakis K, Fiore P, Fortuna M, Fries W, Gaetani E, Galeazzi F, Gasbarrini A, Geccherle' A, Giangregorio F, Girardi L, Grassini M, Groppo M, Guarnieri G, Iovino P, Lo Cascio M, Lolli R, Luzza F, Macarri G, Marino M, Miraglia S, Monastra S, Neri MC, Neri M, Noris RA, Orselli S, Passaretti S, Paviotti A, Pazzi P, Pilotto A, Portincasa P, Ranaldo N, Ravelli P, Rogai F, Sablich R, Savarino V, Spinzi G, Stanghellini V, Tammaro L, Torresan F, Usai Satta P, Valle C., Neri, L, Conway, Pm, Basilisco, G, Stanghellini, V, Neri, L., Conway, P., Basilisco, G., Bonventre, S, Altomare, Df, Annese, V, Badiali, D, Bassotti, G, Battaglia, E, Bazzocchi, G, Bellini, M, Bendia, E, Benini, L, Biscaglia, G, Biviano, I, Bocchini, R, Bonfrate, L, Bossa, F, Brandimarte, G, Cannizzaro, R, Cicala, M, Cipolletta, L, Clara, V, Cogliandro, R, Comandini, G, Corazziari, E, Crotta, S, Cuomo, Rosario, D'Alba, L, De Giorgi, F, Del Piano, M, Di Fonzo, M, Di Mario, Francesco, Di Stefano, M, D'Onofrio, V, Efthymakis, K, Fiore, P, Fortuna, M, Fries, W, Gaetani, E, Galeazzi, F, Gasbarrini, A, Geccherle', A, Giangregorio, F, Girardi, L, Grassini, M, Groppo, M, Guarnieri, G, Iovino, P, Lo Cascio, M, Lolli, R, Luzza, F, Macarri, G, Marino, M, Miraglia, S, Monastra, S, Neri, Mc, Neri, M, Noris, Ra, Orselli, S, Passaretti, S, Paviotti, A, Pazzi, P, Pilotto, A, Portincasa, P, Ranaldo, N, Ravelli, P, Rogai, F, Sablich, R, Savarino, V, Spinzi, G, Tammaro, L, Torresan, F, Usai Satta, P, and Valle, C.

Subjects
Adult, Male, medicine.medical_specialty, Abdominal pain, Constipation, Constipation severity, Chronic constipation, Chronic non-organic constipation, Quality of life, Chronic Disease, Female, Humans, Middle Aged, Patient Care, Quality of Life, Reproducibility of Results, Surveys and Questionnaires, Factor Analysis, Statistical, Public Health, Environmental and Occupational Health, Medicine (all), Reproducibility of Result, Internal medicine, medicine, Criterion validity, Surveys and Questionnaire, Settore MED/12 - Gastroenterologia, business.industry, Minimal clinically important difference, Environmental and Occupational Health, Settore MED/09 - MEDICINA INTERNA, Statistical, medicine.disease, Confirmatory factor analysis, Settore MED/18 - Chirurgia Generale, Physical therapy, Functional constipation, Public Health, medicine.symptom, business, Factor Analysis, Human
Abstract

Background and aim: PAC-SYM is widely adopted to asses constipation severity. However, it has been validated in a small sample, few items have been included based on expert opinion and not on empirical grounds, and its factor structure has never been replicated. We aimed at evaluating the psychometric properties of PAC-SYM in patients with chronic constipation. Methods: We enrolled 2,203 outpatients with chronic constipation in two waves. We used wave I sample to test the psychometric properties of the PAC-SYM and wave II sample to cross-validate its factor structure, to assess criterion validity, responsiveness to clinical change, and its minimal clinically important difference. Results: Only a minority of patients reported any rectal tearing (38 %). Deletion of such item leads to a 11-item version (M:PAC-SYM). The remaining items in the rectal domain were moderately correlated with the stool domain. Exploratory factor analysis and confirmatory factor analysis revealed a bifactor structure with two subscales (stool and abdominal symptoms) and a general severity factor. The M:PAC-SYM demonstrated excellent reliability, moderate correlation with SF-12 and treatment satisfaction (r = 0.28–0.45), discrimination across Rome III criteria for functional constipation and abdominal pain, and responsiveness to clinical change (β = −0.49; ω 2 = 0.25). M:PAC-SYM minimal clinically important difference was 0.24. Conclusion: Our analysis shows that the rectal domain may not represent a relevant cluster of symptoms for patients with chronic constipation. We developed a modified version of the PAC-SYM which might better represent symptom severity of most patients seeking care in gastroenterology referral centers

Published
2014

2. Endoscopic Ultrasonography May Select Subjects Having Asymptomatic Chronic Pancreatic Hyperenzymemia Who Require a Stricter Follow-up

Author

Samuele De Minicis, Filippo Antonini, Nico Pagano, P. Rossetti, S. Piergallini, Elisabetta Buscarini, V. Belfiori, Massimiliano Lo Cascio, B. Marraccini, Raffaele Pezzilli, Elena Andrenacci, Giampiero Macarri, Antonini F., Belfiori V., Pagano N., Buscarini E., De Minicis S., Lo Cascio M., Marraccini B., Piergallini S., Rossetti P., Andrenacci E., MacArri G., and Pezzilli R.

Subjects
Adult, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Endoscopic ultrasonography, hyperamylasemia, Asymptomatic, Endosonography, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Endocrinology, Text mining, Pancreatitis, Chronic, Internal Medicine, Medicine, Humans, Trypsin, pancreatic hyperenzymemia, EUS, Aged, Retrospective Studies, Aged, 80 and over, Hepatology, business.industry, pancreatic cyst, Reproducibility of Results, Lipase, Middle Aged, pancrea, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Pancreatic cyst, Amylases, Hyperamylasemia, 030211 gastroenterology & hepatology, chronic pancreatiti, Female, Imaging technique, Radiology, medicine.symptom, business, Pancreas, Follow-Up Studies
Abstract

Objectives We have previously shown that at least 50% of patients with asymptomatic chronic pancreatic hyperenzymemia (ACPH) may develop morphological pancreatic alterations. Endoscopic ultrasonography (EUS) may detect small lesions, and its sensitivity seems to be higher than other imaging techniques. The aim of this study was to evaluate whether EUS may modify the management of patients having ACPH. Methods In 2 referral centers for pancreatic disease, a retrospective analysis of prospectively enrolled patients with ACPH was conducted. Results Seventy-three patients with ACPH were enrolled for the purpose of this study. Endoscopic ultrasonography was performed as the last examination in 45 subjects who resulted negative at previous imaging studies (abdominal ultrasound, computed tomography, magnetic resonance imaging associated with cholangiopancreatography). Using EUS in 7 subjects, abnormalities were found in the following: 3 branch-duct intraductal papillary mucinous neoplasms, 1 duodenal diverticulum, 1 annular pancreas, 1 findings suggestive of chronic pancreatitis, and 1 undefined cyst (

Published
2017

3. Bloating is associated with worse quality of life, treatment satisfaction, and treatment responsiveness among patients with constipation-predominant irritable bowel syndrome and functional constipation

Author

Neri, L., Iovino, P., Altomare, Donato Francesco, Annese, Vito, Badiali, Danilo, Basilisco, Guido, Bassotti, Gabrio, Battaglia, Edda, Bazzocchi, Gabriele, Bellini, Massimo, Bendia, Emanuele, Benini, Luigi, Biscaglia, Giuseppe, Biviano, Ivano, Bocchini, Renato, Bonventre, Sebastiano, Bossa, Fabrizio, Brandimarte, Giovanni, Cannizzaro, Renato, Cicala, Michele, Cipolletta, Livio, Clara, Virgilio, Cogliandro, Rosanna, Comandini, Giulia, Corazziari, Enrico, Crotta, Sergio, Cuomo, Rosario, D'Alba, Lucia, De Giorgi, Francesco, Del Piano, Mario, Di Fonzo, Michela, Di Mario, Francesco, Di Stefano, Michele, D'Onofrio, Vittorio, Efthymakis, Kostantinos, Fiore, Pierluigi, Fortuna, Manuela, Fries, Walter, Gaetani, Eleonora, Galeazzi, Francesca, Gasbarrini, Antonio, Geccherle, Andrea, Giangregorio, Francesco, Girardi, Lisa, Grassini, Mario, Groppo, Marzia, Guarnieri, Giovanni, Lo Cascio, Massimiliano, Lolli, Roberto, Luzza, Francesco, Macarri, Giampiero, Marino, Maria, Miraglia, Stefania, Monastra, Santo, Neri, Maria Cristina, Neri, Matteo, Noris, Roberto Antonio, Orselli, Silvia, Passaretti, Sandro, Paviotti, Alberto, Pazzi, Paolo, Pilotto, Alberto, Portincasa, Piero, Ranaldo, Nunzio, Ravelli, Paolo, Rogai, Francesca, Sablich, Renato, Savarino, Vincenzo, Spinzi, Giancarlo, Stanghellini, Vincenzo, Tammaro, Leonardo, Torresan, Francesco, Usai Satta, Paolo, Valle, C. Claudio, Neri, L., Iovino, P., Altomare, Donato Francesco, Annese, Vito, Badiali, Danilo, Basilisco, Guido, Bassotti, Gabrio, Battaglia, Edda, Bazzocchi, Gabriele, Bellini, Massimo, Bendia, Emanuele, Benini, Luigi, Biscaglia, Giuseppe, Biviano, Ivano, Bocchini, Renato, Bonventre, Sebastiano, Bossa, Fabrizio, Brandimarte, Giovanni, Cannizzaro, Renato, Cicala, Michele, Cipolletta, Livio, Clara, Virgilio, Cogliandro, Rosanna, Comandini, Giulia, Corazziari, Enrico, Crotta, Sergio, Cuomo, Rosario, D'Alba, Lucia, De Giorgi, Francesco, Del Piano, Mario, Di Fonzo, Michela, Di Mario, Francesco, Di Stefano, Michele, D'Onofrio, Vittorio, Efthymakis, Kostantino, Fiore, Pierluigi, Fortuna, Manuela, Fries, Walter, Gaetani, Eleonora, Galeazzi, Francesca, Gasbarrini, Antonio, Geccherle, Andrea, Giangregorio, Francesco, Girardi, Lisa, Grassini, Mario, Groppo, Marzia, Guarnieri, Giovanni, Lo Cascio, Massimiliano, Lolli, Roberto, Luzza, Francesco, Macarri, Giampiero, Marino, Maria, Miraglia, Stefania, Monastra, Santo, Neri, Maria Cristina, Neri, Matteo, Noris, Roberto Antonio, Orselli, Silvia, Passaretti, Sandro, Paviotti, Alberto, Pazzi, Paolo, Pilotto, Alberto, Portincasa, Piero, Ranaldo, Nunzio, Ravelli, Paolo, Rogai, Francesca, Sablich, Renato, Savarino, Vincenzo, Spinzi, Giancarlo, Stanghellini, Vincenzo, Tammaro, Leonardo, Torresan, Francesco, Usai Satta, Paolo, Valle, C. Claudio, Altomare, D., Annese, V., Badiali, D., Basilisco, G., Bassotti, G., Battaglia, E., Bazzocchi, G., Bellini, M., Bendia, E., Benini, L., Biscaglia, G., Biviano, I., Bocchini, R., Bonventre, S., Bossa, F., Brandimarte, G., Cannizzaro, R., Cicala, M., Cipolletta, L., Clara, V., Cogliandro, R., Comandini, G., Corazziari, E., Crotta, S., Cuomo, R., D'Alba, L., De Giorgi, F., Del Piano, M., Di Fonzo, M., Di Mario, F., Di Stefano, M., D'Onofrio, V., Efthymakis, K., Fiore, P., Fortuna, M., Fries, W., Gaetani, E., Galeazzi, F., Gasbarrini, A., Geccherle, A., Giangregorio, F., Girardi, L., Grassini, M., Groppo, M., Guarnieri, G., Lo Cascio, M., Lolli, R., Luzza, F., Macarri, G., Marino, M., Miraglia, S., Monastra, S., Neri, M., Noris, R., Orselli, S., Passaretti, S., Paviotti, A., Pazzi, P., Pilotto, A., Portincasa, P., Ranaldo, N., Ravelli, P., Rogai, F., Sablich, R., Savarino, V., Spinzi, G., Stanghellini, V., Tammaro, L., Torresan, F., Usai Satta, P., and Valle, C.

Subjects
Adult, Male, Quality of life, medicine.medical_specialty, Constipation, Cross-sectional study, Physiology, Bloating, Chronic constipation, Functional constipation, Irritable bowel syndrome, Patient-reported outcomes, Treatment satisfaction, Endocrine and Autonomic Systems, Gastroenterology, Cross-Sectional Studies, Female, Flatulence, Humans, Irritable Bowel Syndrome, Middle Aged, Prevalence, Quality of Life, Surveys and Questionnaires, Endocrine and Autonomic System, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Patient-reported outcome, Settore MED/12 - Gastroenterologia, business.industry, Settore MED/09 - MEDICINA INTERNA, medicine.disease, Settore MED/18 - Chirurgia Generale, Tolerability, 030220 oncology & carcinogenesis, Physical therapy, 030211 gastroenterology & hepatology, medicine.symptom, business
Abstract

Background The management of bloating is unclear and its relationship with patients' well-being and treatment satisfaction independent of other abdominal symptoms is uncharacterized. We evaluated the association of bloating with patient-reported outcomes. Methods Thirty-nine centers for functional gastrointestinal disorders joined the laxative inadequate relief survey. We enrolled 2203 consecutive outpatients with functional constipation (FC) or constipation-predominant irritable bowel syndrome (IBS-C) in two cross-sectional waves. Both wave 1 and 2 included the SF-12, the patient assessment of constipation-symptoms (PAC-SYM), and the treatment satisfaction questionnaire for medication (TSQM-2). Wave 2 only included a global rating of change (GRC) scale to assess patients' assessment of efficacy concerning treatment switches occurred in the 3 months prior to the interview. Bloating in the abdomen was defined on the basis of PAC-SYM item 3. Key Results The average age was 50.1 years (SD, 16.7) and 82.1% of patients were women. The prevalence of bloating was 91.6% (n = 1970). Bloating was associated with SF-12 Physical Composite Score (p < 0.01), SF-12 Mental Composite Score (p < 0.01), GRC (p < 0.01), Satisfaction with treatment effectiveness (p < 0.01), convenience of administration (p < 0.01), and side effects (p < 0.01) after adjustment for possible confounders. Conclusions & Inferences Our data suggest that patients regard bloating as a key element in assessing clinical changes and treatments' efficacy as this symptom exerts a strong influence on patient-reported outcomes independent of possible confounders and other symptoms of constipation. Our data provide the rationale to investigate the efficacy and tolerability of new treatments specifically addressing this important, yet disregarded, patients' complain.

Published
2016

4. Environmental factors that distinguish between clinical and healthy samples with childhood experiences of abuse and neglect

Author

Maria Rita Infurna, Maria Lo Cascio, Peter Parzer, Cinzia Guarnaccia, Michael Kaess, Francesca Giannone, Infurna, M, Giannone, F, Guarnaccia, C, Lo Cascio, M, Parzer, P, Kaess, M, Université de Palerme (Univ. Palerme), Université de palerme, Dipartimento di Informatica e Sistemistica 'Antonio Ruberti' (DIS), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Laboratoire de Psychologie : Cognition, Comportement, Communication (LP3C - EA1285), Université de Bretagne Sud (UBS)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut Brestois des Sciences de l'Homme et de la Société (IBSHS), Université de Brest (UBO), Heidelberger Instittut für Tiefenpsychologie [Heidelberg] (HIT), and Heidelberger Instittut für Tiefenpsychologie

Subjects
Child abuse, Adult, Male, medicine.medical_specialty, CECA interview, media_common.quotation_subject, MEDLINE, [SHS.PSY]Humanities and Social Sciences/Psychology, Environment, Neglect, [SHS]Humanities and Social Sciences, Social support, Young Adult, Childhood maltreatment, medicine, Humans, Child Abuse, Young adult, Psychiatry, Child, media_common, Middle Aged, Social engagement, Mental health, Environmental factor, Clinical Psychology, Psychiatry and Mental Health, CECA, Female, Psychology, Psychopathology
Abstract

Background: Childhood maltreatment is associated with a wide range of problems in adulthood. However, specific environmental factors (either positive or negative) influence mental health outcomes in maltreated children. The present study investigated the effect of environmental factors by comparing a group of clinical participants with experiences of abuse/neglect with a healthy group with similar patterns of experiences. Environmental factors selected were: separation from parents, financial hardship, parental psychiatric disorders, and low social involvement. Method: The study included 55 mixed clinical participants and 23 healthy participants. All participants were investigated using the Childhood Experience of Care and Abuse (CECA) interview. The two groups were specifically matched with regard to patterns of childhood maltreatment. Results: The findings indicated that psychopathological outcome was associated with a greater presence of negative environmental factors (p < 0.001). In particular, lack of social support seemed to be the only one predictor (OR = 27.86). Conclusion: This study is the first to investigate the influence of specific environmental factors in two groups with similar childhood experiences of abuse/neglect but different mental health outcomes. These findings suggest that efforts should be made to incorporate both familial and external sources of social support in promoting mental health for maltreated children.

Published
2015

Catalog

Books, media, physical & digital resources
See catalog results