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Introducción. Para diagnosticar trastorno por déficit de atención con hiperactividad (TDAH) en niños y adolescentes, es necesario identificar la coexistencia de comorbilidades afectivo-comportamentales que complejizan la evaluación y los procesos terapéuticos requeridos.Objetivo. Describir la comorbilidad afectivo-comportamental asociada a los diferentes subtipos del TDAH en niños y adolescentes de Manizales.Materiales y métodos. Muestra conformada por 141 participantes entre los 5 y 15 años de edad, escolarizados, diagnosticados con TDAH y coeficiente intelectual mayor o igual a 85. Estudio exploratorio-descriptivo, donde se analizaron registros de la entrevista neuropsiquiátrica internacional (MINI-KID).Resultados. El rango de edad con mayor asociación comórbida está entre los 8 y 11 años. El subtipo de TDAH predominante es el combinado. El 32% de la muestra presenta asociación comórbida afectivo-comportamental y los trastornos internalizantes tienen una representación del 68.8%, siendo la fobia simple específica la comorbilidad más preponderante en 80.6% de los casos.Conclusiones. La fobia simple específica es el trastorno internalizante más frecuente en el estudio en rangos de edad y subtipos de TDAH. El trastorno oposicionista desafiante es la comorbilidad externalizante predominante y exclusiva del subtipo de TDAH combinado. Introduction: In order to diagnose attention deficit hyperactivity disorder (ADHD) in children and adolescents, identifying the coexistence of affective-behavioral comorbidities is necessary since they complicate the required evaluation and therapeutic processes.Objective: To describe the affective-behavioral comorbidity associated to the different subtypes of ADHD in a sample of children and adolescents in Manizales, Colombia.Materials and methods: The sample consisted of 141 participants aged between 5 and 15 years, attending school, diagnosed with ADHD and with iq greater than or equal to 85. An exploratory-descriptive study was conducted in which records of the international neuropsychiatric interview (MINI-KID) were analyzed.Results: 8-11 years is the most common age range in which comorbid association is found, and combined ADHD is the most frequent subtype. 32% of the sample presents comorbid affective-behavioral association and internalizing disorders represent 68.8%, with simple phobia as the most prevalent comorbidity in 80.6% of the cases.Conclusions: Simple phobia is the most frequent internalizing disorder in the study, both in age ranges and ADHD subtype. Oppositional defiant disorder is the most common externalizing comorbidity of the combined ADHD subtype.

Introduction Parkinson's disease of juvenile onset is known to be rarely seen in clinical neurology. Occasionally it may be secondary to other pathological processes which have to be excluded by investigation of such cases, since the clinical, therapeutic and prognostic significance varies considerably depending on whether the condition is idiopathic or secondary. Clinical case We present the case of a patient whose illness started when she was 16 years old. She complained of rigidity, tremor and akinesia. Her condition was studied to find whether the syndrome was secondary. Thus, on four occasions, at annual visits during a period of five years, immunological changes suggestive of systemic lupus erythematous were observed. Neuroimaging, magnetic resonance and computerized axial tomography studies were completely normal on all four occasions over the five years during which the patient had annual follow-up reviews. Conclusion We considered whether the rigidity-akinesia-tremor syndrome might have been secondary to systemic lupus erythematous, due to a probable pathological focus of cerebral vasculitis, in this clinical case which we report.