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2. Exclusive chemotherapy in head and neck cancer

Author

Ollivier Laccourreye, Daniel Brasnu, D. Khayat, P. Bonfils, Madeleine Ménard, V. Bassot, Henri Laccourreye, J. Trotoux, Jacquillat C, and E. Chabardes

Subjects
Oncology, Cisplatin, medicine.medical_specialty, Chemotherapy, business.industry, medicine.medical_treatment, Head and neck cancer, medicine.disease, Internal medicine, Continuous perfusion, medicine, business, Small tumors, medicine.drug
Abstract

Over the past decade, with the important development of neo-adjuvant chemotherapy associating cisplatin and 5 FU (CF), a major change in the indication of chemotherapy in head and neck cancer has taken place. There is still an ongoing discussion regarding the results in term of survical. Despite these controversies, some facts appear to be obvious: prognosis is better for patients with complete clinical response (CCR); rate of CCR is better in small tumors (T1 – T2) than in large tumors (T3 – T4).

Published
1991
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