1. Perioperative mortality and morbidity of hip fractures among COVID-19 infected and non-infected patients: A systematic review and meta-analysis
- Author
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Sibasish Panigrahi, Bijnya Birajita Panda, Ramesh Kumar Sen, Anand Srinivasan, Sujit Kumar Tripathy, and Paulson Varghese
- Subjects
medicine.medical_specialty ,MEDLINE ,Article ,Hip fracture ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Medicine ,Orthopedics and Sports Medicine ,Mortality ,030222 orthopedics ,Femur fracture ,Pandemic ,business.industry ,Mortality rate ,COVID-19 ,030208 emergency & critical care medicine ,Odds ratio ,Perioperative ,medicine.disease ,Pneumonia ,Meta-analysis ,Femur neck fracture ,Surgery ,business - Abstract
PURPOSE: Hip fractures among elderly patients are surgical emergencies. During COVID-19 pandemic time, many such patients could not be operated at early time because of the limitation of the medical resources, the risk of infection and redirection of medical attention to a severe infective health problem. METHODS: A search of electronic databases (PubMed, Medline, CINAHL, EMBASE and the Cochrane Central Register of Controlled Trials) with the keywords "COVID", "COVID-19â³, "SARS-COV-2", "Corona", "pandemic", "hip fracture", "trochanteric fracture" and "neck femur fracture" revealed 64 studies evaluating treatment of hip fracture in elderly patients during COVID-19 pandemic time. The 30-day mortality rate, inpatient mortality rate, critical care/special care need, readmission rate and complications rate in both groups were evaluated. Data were analyzed using Review Manager (RevMan) V.5.3. RESULTS: After screening, 7 studies were identified that described the mortality and morbidity in hip fractures in both COVID-19 infected (COVID-19 +) and non-infected (COVID-19 -) patients. There were significantly increased risks of 30-day mortality (32.23% COVID-19 + death vs. 8.85% COVID-19 - death) and inpatient mortality (29.33% vs. 2.62%) among COVID-19 + patients with odds ratio (OR) of 4.84 (95% CI: 3.13-7.47, p
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- 2023