1. Dermatologic conditions in Down syndrome
- Author
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Leah Belazarian, Jillian F. Rork, Kishore Vellody, and Chenin Ryan
- Subjects
Down syndrome ,medicine.medical_specialty ,business.industry ,Folliculitis ,Dermatology ,medicine.disease ,Skin Diseases ,Seborrheic dermatitis ,Psoriasis ,Pediatrics, Perinatology and Child Health ,medicine ,Humans ,Hidradenitis suppurativa ,Down Syndrome ,Skin cancer ,Chromosome 21 ,Trisomy ,business ,Skin - Abstract
Down syndrome (DS) is the most common chromosomal condition and affects many organs including the skin. Dermatologists are an integral part of the DS care team. This is a review of both common and rare dermatologic conditions in DS. We provide practical strategies for a successful dermatology interview and examination. We explore the downstream effects of trisomy of chromosome 21, in particular on the immune system, and how these insights may enhance our pathophysiologic understanding of their cutaneous conditions.
- Published
- 2021