1. Editor's Choice – Decrease in Mortality from Abdominal Aortic Aneurysms (2001 to 2015): Is it Decreasing Even Faster?
- Author
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Edward Choke, Tay J. Sheng, Tjun Y. Tang, Jingting Wu, Ivan P. L. Png, and C.Y. Maximilian Png
- Subjects
Blood pressure control ,medicine.medical_specialty ,medicine.medical_treatment ,Population ,030204 cardiovascular system & hematology ,030230 surgery ,World health ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Epidemiology ,Prevalence ,Humans ,Medicine ,Mortality ,Mortality trends ,education ,education.field_of_study ,business.industry ,Disease Management ,medicine.disease ,Obesity ,Heart Disease Risk Factors ,Smoking cessation ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,Aortic Aneurysm, Abdominal ,Demography - Abstract
Objective The early twenty first century witnessed a decrease in mortality from abdominal aortic aneurysms (AAA), which was associated with variations in the prevalence of cardiovascular risk factors. This study investigated whether these trends continued into the second decade of the twenty first century. Methods Information on AAA mortality (2001 − 2015) using International Classification of Diseases codes was extracted from the World Health Organization (WHO) mortality database. Data on risk factors were extracted from the Institute of Health Metrics and Evaluation and WHO InfoBase, and data on population from the World Development Indicators database. Regression analysis of temporal trends in cardiovascular risk factors was done independently for correlations with AAA mortality trends. Results Seventeen countries across four continents met the inclusion criteria (Australasia, two; Europe, 11; North America, two; Asia, two). Male AAA mortality decreased in 13 countries (population weighted average: −2.84%), while female AAA mortality decreased in 11 countries (population weighted average: −1.64%). The decrease in AAA mortality was seen in both younger ( 65 years) patients. The decrease in AAA mortality was more marked in the second decade of the twenty first century (2011 – 2015) compared with the first decade (2001 – 2005 and 2006 – 2010). Trends in AAA mortality positively correlated with smoking (males: p = .03X, females: p = .001) and hypertension (males: p = .001, females: p = .01X). Conversely, AAA mortality negatively correlated with obesity (males: p = .001, females: p = .001), while there was no significant correlation with diabetes. Conclusion AAA mortality has continued to decline and seems to have declined at an even faster rate in the second decade of the twenty first century, albeit with heterogeneity among countries. These variations are multifactorial in origin but further efforts targeting smoking cessation and blood pressure control will probably contribute to continued reductions in AAA mortality.
- Published
- 2021