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Purpose: Existing studies have identified sexual minorities as being at enhanced risk for reporting synthetic cannabinoid (SC) use. It is unclear whether this association is the result of those that identify as a minority due to sexual orientation being more likely to use SCs, due to those that identify as transgender using SCs more, or both. Deconstructing this relationship will allow for targeted clinical advice and public health campaigns. Methods: Data from the 2015 and 2017 Youth Risk Behavior Study are utilized. In total, 31,279 youth were asked about their gender identity, sexual orientation, and SC use history. Bivariate analyses and logistic regression models were completed to explore relevant associations. Results: Identifying as lesbian, gay, bisexual, or questioning was linked to SC use and continuing SC use. Similarly, identifying as transgender was linked to SC use and continuing use. Regression analyses showed no significant interactive effect; identifying as both LGBQ and transgender does not have a compounding effect on use likelihood. Conclusions: Both sexual orientation and gender identity contribute to the relationship between sexual minority status and SC use noted in extant literature. This relationship is hypothesized to be tied to increased exposure to discrimination, victimization, and social isolation. Thus, efforts to directly counsel LGBTQ patients about the dangers associated with SC use are warranted as well as social policy reforms to better protect and support members of the LGBTQ community.

To provide an updated profile of school-aged synthetic cannabinoid users in the U.S. by examining the factors associated with synthetic cannabinoid (SC) use. Data from the 2015 and 2017 Youth Risk ...

Aims To examine the continuing role of daily popular social media use in youth hazardous alcohol consumption in four countries across continents. Methods A web-based survey was given to youths aged 15–25 in the USA (n = 1212), South Korea (n = 1192), Finland (n = 1200) and Spain (n = 1212). Hazardous alcohol use (alcohol use disorders identification test-C) was the dependent variable. Main independent variables measured daily use of different social media services. Controls included compulsive Internet use, offline belonging, psychological distress, impulsivity, risk-taking, age and gender. Linear regression models and mediation analyses with bootstrapping were done for each country. Results Daily use of Facebook and Instagram was associated with higher hazardous alcohol use among youths in Finland, South Korea and Spain. Daily instant messaging was related to higher hazardous alcohol use among South Korean and Finnish youths. Daily YouTube use was associated with higher hazardous alcohol use among youths in South Korea, but lower hazardous alcohol use among youths in the USA and Finland. Daily Twitter use was related to lower hazardous drinking among youths in Finland but higher hazardous drinking among youths in Spain. The mediation analyses revealed that uploading pictures to social media is a possible facilitator of social media-related hazardous alcohol use among youths in the USA and Spain. Conclusion Certain social media platforms might inspire and/or attract hazardously drinking youths, contributing to the growing opportunities for social media interventions.

From the anti-tobacco and anti-marijuana campaigns of the twentieth century to the current controversies surrounding vaporizer use and the opioid epidemic, substances and substance use have been at the forefront of cultural, public health, and legal debates for decades. This work explores treatment outcomes among those with substance use disorders (SUD) by 1) comparing legal, semi-legal, and illegal drug types and their impact on treatment outcomes and 2) evaluating the extent that there exist discrepancies between those who need and those who receive treatment.

The use of marijuana concentrates has escalated in recent years with butane extracts appearing particularly popular. The administration of butane hash oil, colloquially referred to as “dabbing,” is distinct from traditional flower cannabis usage due to the THC content of samples and the presence of impurities such as unpurged butane. While this may confer heightened risk to the user, additional significant concerns are tied to fires and explosions. Using butane as a solvent in amateur “blasting” methods may result in a flammable vapor pooling in enclosed spaces and igniting when exposed to a spark. As research on butane extract users, amateur production techniques, health risks, and legality is in its infancy, we explored existing studies on the topic to create a review of substantiated knowledge related to THC extracted using butane. The resulting assessment centers on three areas: 1) dab users including both recreational users and medical marijuana patients; 2) butane extraction techniques including illicit amateur open methods and the safer closed-loop system employed in medicinal/recreational states; and 3) risks, both related to fires and legality. We follow the presentation of this material with a summary of the (mis)information reaching the public in print and online sources so that public educational campaigns can focus on dispelling the inaccuracies and false notions of safety that may be tied to amateur production., Video abstract

The current study focuses on predominant predictors associated with men’s and women’s engagement in driving under the influence (DUI) in an attempt to determine whether gender-specific interventions would be more affective at reducing impaired vehicle operation. A male-only subsample (n = 863) and a female-only subsample (n = 975) from a survey administered at a large Southeastern university containing self-reported measures of DUI were used to evaluate gender differences in motivations and correlates of DUI behavior. A series of logistic regressions containing indicators drawn from theories of deviant behavior (e.g., Akers’ social learning theory (SLT) and Gottfredson and Hirshi’s low self-control (LSC) theory) yield results indicating that differential association and imitation, both factors associated with SLT, are significant predictors for both gender cohorts’ DUI behavior. Low self- control was a significant predictor within female-only models, but not the final male-only models. This suggests that peer associations and modeling may be targets of intervention generally, but that, as it relates to DUIs, women may particularly benefit from programs focused at limiting impulsivity and risk-taking behavior as these are components of Gottfredson and Hirschi’s LSC construct.

Introduction and Aims Acetyl fentanyl, a fentanyl analogue emerging onto the recreational drug scene, has been responsible for numerous recent fatal overdoses in the USA, Europe and Russia. Studies reporting acetyl fentanyl use are presently limited to case studies and mortality reports. This study explores the nature of acetyl fentanyl use through the collection of first-hand qualitative data from users to inform public health and drug control policy responses. Design and Methods A series of focus group interviews within a correctional setting—Delaware County (Ohio) Jail, USA. Participants were 102 individuals in one of two US Bureau of Justice Assistance Second Chance Act substance use treatment initiatives participating in at least one focus group session. Five of these individuals reported acetyl fentanyl use. Semi-structured qualitative focus group sessions queried subjects' drugs of choice and nature of drug use. Responses were explored through follow-up organic discourse. Results Acetyl fentanyl users were generally unaware that they had administered the substance until after use (initially believing that they were administering heroin). They described the effects of acetyl fentanyl as stronger and qualitatively different from heroin. These individuals showed no interest in using acetyl fentanyl again describing it as unpleasant and more risky, both because of potency and the threat of a ‘bad batch’. Discussion and Conclusions Acetyl fentanyl is reaching heroin users, some of which administer it unknowingly. Regulation of acetyl fentanyl is recommended in all countries as is increasing public awareness that the substance is distinct from and being sold as heroin. [Miller JM, Stogner JM, Miller BL, Blough S. Exploring synthetic heroin: Accounts of acetyl fentanyl use from a sample of dually diagnosed drug offenders. Drug Alcohol Rev 2018;37:121–127]

Illicit drugs are sold online. Besides cryptomarkets, young people today are also using social media to buy and sell different drugs. The aim of this nationwide study was to investigate the phenomenon of buying drugs from social media among American young people. Relatively few studies have investigated young people buying drugs online and, therefore, it is important to know more about the psychological and social risk factors of this behavior. The participants of the study were 15–25-year-olds from the U.S. (M = 20.05; 50.17% female). Buying drugs online was utilized as an outcome variable. The covariates included measures of impulsivity and delay of gratification, sense of belonging to online communities, online homophily, friends sharing risk material online, psychological distress, and measures for addictive behaviors including hazardous drinking, problem gambling, and compulsive Internet use. Results showed that buying drugs online is still a relatively rare phenomenon, but many of those buying drugs online used social media services to do so. Buying drugs online was associated with higher impulsivity and lower measures of delay discounting indicating self-control problems. Online buyers also had multiple problems with mental wellbeing, as they reported more psychological distress, problem gambling, and compulsive Internet use than those drug users who had not bought drugs online. The existence and comorbidity of these problems suggest that drug availability online might worsen their situation. As impulsive decisions are especially easy to make on social media, more focus should be placed on youth behavior on mainstream social media services.

Novel psychoactive drugs (NPDs), an emerging class of dangerous substances, generally mimic the actions of commonly abused substances such as marijuana, stimulants, hallucinogens, and opiates, but are formulated, marketed, and used either to sidestep legal restrictions or to avoid positive drug screens. Synthetic cannabinoids such as Spice and K2 along with synthetic stimulants often referred to as “bath salts” have recently entered U.S. markets. The current study explores the relationship between being arrested and using NPDs per self-report survey data obtained from 2,349 students at a large university in the Southeastern United States. Respondents indicated whether they had used synthetic psychoactive drugs, reported demographic characteristics, and whether they had been arrested for a number of offenses. Results from logistic regression and propensity score matching models indicate that those who have been arrested are also more likely to use NPDs.

Purpose: Most research examining patient-based drug diversion neglects to assess physician deception directly. We attempt to determine if motives for deception are linked to success, and, similarly, if any health, demographic, or substance use history characteristics of the patients are predictive of being able to successfully deceive a physician. Methods: Stratified random sampling was utilized to obtain a sample of 2349 young adults. Respondents completed a survey detailing their substance use histories and whether they had ever deceived a physician for medication. Ninety-three of these respondents reported attempting to deceive a physician for a medication and compose the analytic sample for the study. Results: Of the 93 young adults who reported having attempted to deceive a physician for pharmaceuticals (4.0% of the general sample), 64 (68.8%) were successful. This included 24 only seeking medications for their own use, 9 only for financial purposes, and 31 with both motives. Respondents who reported recreationally using pharmaceuticals in the past were more likely to report successful attempts at obtaining a prescription compared with respondents without a history of abuse. With respect to demographic characteristics of the respondents, only race/ethnicity distinguished between successful attempts and failure. Conclusions: Although a rare occurrence in the overall sample, significant correlates of successful deception did emerge. Respondents motivated to obtain a prescription in order to sell it to others were overwhelmingly likely to succeed in their pursuit to deceive as compared with respondents who sought prescriptions for their own abuse. Successful deceivers were also more likely to have been legitimately prescribed medication in the past. Successful respondents were more likely to be Caucasian than any other race/ethnicity.

Novel psychoactive drugs (NPDs) such as synthetic marijuana, bath salts, and salvia have increasingly entered into the American drug landscape. As law enforcement, researchers, and policy makers attempt to better understand, regulate, and detect these novel substances, other practitioners invested in drug abuse prevention and treatment may lack the knowledge to adequately handle patients and adolescents abusing NPDs. The current study employs interviews with 64 practitioners employed in positions that interact with potential recreational substance users in southeast Georgia in order to assess NPD knowledge, placing particular emphasis on those 22 respondents employed in public health, healthcare, or educational roles. Findings indicate that knowledge about NPDs among medical and educational practitioners is lacking, much of the information they ‘know’ is inaccurate, and that practitioners clearly recognize a need for NPD training. We discuss these findings relative to their broader impact on treatment and prevention programs.

The use of psychoactive drugs appears to have a clear influence on both friendship formation and friendship quality. Differences in the frequency of substance use are particularly likely to influence each friend’s perceptions of their relationship with the other. However, the impact of divergent substance use patterns within a friendship dyad on overall friendship quality remains an underexplored area. Self-reported alcohol use and perceptions of friendship quality data were collected from 2,154 students (mean age = 19.3) in 1,077 friendship dyads. Analyses of variance were conducted to determine (a) if friends who have similar alcohol use patterns perceive greater friendship quality than friends with dissimilar use patterns, and (b) how dissimilarities in drinking behaviors between friends affect individuals’ perceptions of friendship quality. Individuals in dyads comprised of friends with similar drinking patterns were found to experience higher quality relationships than those in friendships with dissi...

Background Though case studies, media reports, and anecdotal evidence point to creative forms of alcohol use such as “eyeballing,” inhalation through vaporizers and other “alcohol without liquid” (AWOL) devices, and “slimming” as a growing trend, no empirical study has assessed the veracity of these claims. The present study attempts to debunk, confirm, or alter the popular perception that young adults are administering alcohol in novel ways. Methods A self-report paper survey was administered to 2349 young adults selected for inclusion using a stratified random sampling technique. Respondents were asked to indicate all of the ways in which they had administered alcohol and presented options ranging from traditional oral consumption from a cup, can, or bottle to innovative techniques referenced by medical reports and news outlets. The prevalence of each form of innovative use was reported and explored. Results Innovative alcohol use was very rare in the sample. Only 25 of 2349 participants (1.1%) had engaged in one or more of the creative methods of alcohol consumption. Among these individuals, most reported either using an AWOL device and/or administering alcohol anally. Vaginal administration and “eyeballing” were only reported by three and one respondents, respectively. Conclusions It appears that innovative alcohol use is more than an urban legend but that innovative use, even among a population with high rates of alcohol and drug use, is rare. Regardless, physicians and emergency medical personnel need to be aware of and prepared for dealing with innovative alcohol use.

Background: Pharmaceutical abuse is a burgeoning problem, and various forms of drug diversion are becoming more common. At present, little is known about those who attempt to deceive physicians to receive medications, and even less is known about those who successfully avoid detection and abuse-related repercussions. The goal of this study is to assess the prevalence of attempted physician deception in a general population, explore common motives, and evaluate risk factors associated with the behavior. Methods: A stratified random sampling technique was used to obtain a locally representative sample of 2349 young adults. The sample was 48.4% male, 68.9% white, 24.4% black, and 2.8% Hispanic. Selected individuals were surveyed using a self-report instrument (80.4% response rate). Results: Of the respondents, 93 (4.0%) self-reported having attempted to deceive a physician to obtain a pharmaceutical. Most of these indicated that they were at least partially motivated by their own abuse. Approximately half reported that selling a portion of the prescription was a motivating factor. Alcohol use, marijuana use, and pharmaceutical misuse each were risk factors associated with attempted deception. Although no traits were definitively linked to the behavior, attempted deception was more commonly reported by men, Hispanics, self-identified lesbian/gay/bisexual/transgender individuals, and those at the lowest and highest extremes of the income spectrum. Logistic regression models of rare events indicated that past substance use along with sexual orientation and family income were related to attempted deception when controlling for other factors. Conclusion: Results suggest that attempted physician deception may be more common than previously believed. Practicing physicians should attempt to use risk factor information presented within this study, albeit very cautiously. This study identifies general characteristics of young people who might divert medications but notes that only a small minority of any patient group will do so. Awareness should not equal bias in the treatment of these patients; instead, it should reinforce the need for careful clinical interviewing and the utilization of prescription drug monitoring programs and local law enforcement databases.

Recent social and legal responses to novel psychoactive drugs (NPDs) have been attributed to media panics rather than these substance’s actual harms. NPDs, including botanical substances new to Western markets such as Salvia divinorum, newly synthesized analogues such as synthetic cannabinoids and “bath salts,” and new ways of administering drugs, such as combining prescription cough syrup with soda (“purple drank”) have been the target of various forms of legislation at the state and/or federal level. We systematically examine print media coverage of NPDs in the U. S. between 2005 and 2013 to determine whether media attention was temporally associated with legislative change. Results indicate that each drug had a brief window during which it was the focus of sensationalistic reporting. In addition, federal legislation banning synthetic cannabinoids and “bath salts” appear to be closely linked to media reporting as spikes in coverage both preceded and followed the bans.

This research examines the characteristics of users of synthetic stimulants marketed as "bath salts." Synthetic stimulants such as MDPV (3,4-Methylenedioxypyrovalerone), Mephedrone (4-Methylmethcathinone), and Methylone (3,4-Methylenedioxymethcathinone) are often contained in products sold at convenience stores and over the Internet in the United States. Despite the recent legal action banning these types of synthetic stimulants, little is known about the characteristics of the users of these substances. This research provides a profile of bath salt users in the United States among an emerging adult population. A self-report survey instrument was administered to 2,349 students at a large university in the southeastern United States. Respondents indicated whether they had used synthetic stimulants and reported demographic characteristics. Results indicated that users of bath salts were more likely to be male, Hispanic or Native American, student athletes, employed, identify as a members of the LGBT community, and users of other substances.

In recent years, use of substances commonly referred to as ‘legal highs’ has become a significant concern to policy makers and public health officials. Though legislation banning the use and possession of these novel and synthetic drugs often follows the initial media attention and public outcry, potential users may often be unaware of the legislation. A survey including self-reported drug use and perceptions of the legality of various psychoactive substances was administered to 2,346 students in randomly selected classes at a large public university to determine what portion accurately knew four types of novel drugs were locally illegal. Results indicated that numerous potential and current users incorrectly believed that the former ‘legal highs’ remained unrestricted. This sample did include a number of novel drug users; lifetime use of at least one novel drug was reported by 17.1 %, many of which reported using multiple types of novel drugs. Approximately one-third of the overall sample inaccurately believed that Salvia divinorum (34.7 %), K2/Spice (36.5 %), and Mr. Miyagi/Pot-pourri (32.1 %) were legal in the state and over half (50.3 %) inaccurately believed ‘bath salts’ (synthetic cathinones, MDPV, and other synthetic stimulants) remained legal. As these misperceptions have the potential to influence substance use decisions, they may need to be corrected through educational campaigns as widespread as the preceding media coverage that labeled the drug as ‘legal highs.’ Results also indicated that Blacks and previous users of the substances were more likely to hold inaccurate legal beliefs.

Misperceptions of peer substance use have previously been implicated as significant influences on individual use of both alcohol and illicit drugs. However, research on perceived social norms and related interventions are typically limited to binge drinking and marijuana and no empirical studies have explored misperceptions related to “novel drugs.” The present study explored the extent of use and perceptions of use among a college sample ( N = 2,349) for three categories of novel drugs: synthetic cannabinoids (Spice, K2, Mr. Miyagi, Pot-Pourri, etc.), synthetic cathinones (commonly known as “bath salts”), and Salvia divinorum. Results indicate that overall perceived use was significantly higher than actual reported use. The frequency of overestimation of peer use was particularly large for the emerging drugs when compared to alcohol and marijuana. This finding is concerning as these misperceptions have the potential to influence students toward experimentation with these substances and suggests that a possible target for intervention is misperceptions of emerging novel substances.

Purple drank" is a label typically applied to mixtures of codeine cough syrup with soda, although it has also been applied to mixtures of over-the-counter cough syrups and alcohol. This novel drug formulation was first popularized in the Houston, Texas rap music scene in the 1990's, and since then references to purple drank have become common in rap and hip-hop songs, but remained virtually absent in other musical genres. Prior research has found that musical preferences can have an influence on choice and frequency of drug use. The goal of the present study is to examine the relationship between musical preferences and experimentation with purple drank. Self-reported information about musical preferences, substance use, and demographic characteristics were collected from 2,349 students at a large uni- versity in the southeastern United States. An analysis of lifetime purple drank and other drug use by musical preferences reveals that those who prefer rap/hip-hop music and rock/alternative have the highest risk for reporting purple drank use. Further, this relationship far exceeds the associations between musical preferences and other drugs. Results from logistic regression analyses indicate males, other drug users, and those that prefer rap/hip-hop music have a significantly higher likelihood of using purple drank.

Aims: Over the last 6 years, numerous products have been made available and marketed as “legal highs.” Many of these products contain compounds similar to those within cannabis and function to create a high comparable to that of smoking marijuana. Though governments have regulated these psychoactive compounds, variants are still sold. At this point, little is known about the characteristics of users of synthetic cannabinoids. Design and Participants: A self-report survey instrument was administered to 2349 university students at a large institute in the State of Georgia. Respondents reported on their lifetime, last-year, and last-month synthetic cannabinoid use and demographic characteristics. Results: Males, Whites and Hispanics, users of other substances, and those from more affluent families were significantly more likely to report having used a synthetic cannabinoid. In addition, those that self-identified as lesbian, gay, bisexual, or transgender (LGBT) were twice as likely to have used synthetic can...

Background A plant with dissociative and psychoactive properties began to attract the attention of the media and United States policymakers following a well-publicized suicide in 2006 and reports that the plant served as a ‘legal high' and substitute for cannabis. As a result, Salvia divinorum and its active ingredient, salvinorin A, were classified as Schedule I substances by the Florida Legislature on July 1, 2008. As of yet, no research has explored the efficacy of this policy or similar policies in other jurisdictions. Methods Three self-report studies collected from young adults both prior to and following the policy's implementation are employed to investigate the potential relationship between the policy and usage rates. In addition, law enforcement personnel from the state's most populated areas were interviewed to determine the extent to which they were encountering salvia in their work. Results It was indicated that less than two-thirds of those surveyed were aware of the drug's legal status. Lifetime prevalence of salvia use was largely unchanged. However, the rates of self-reported past year and past month use in Florida were significantly lower following the scheduling. Though use of Salvia divinorum appears to have decreased, perceptions of peer use increased markedly. Law enforcement officers and laboratories reported rarely, if ever, dealing with cases of salvia possession. Conclusions Data suggests the classification of Salvia divinorum as a Schedule I drug was followed by a substantial reduction in recreational use. We caution that other factors may have influenced use, that the efficacy of scheduling novel substances is likely to vary by drug type, that such a reduction in reported use may only exist transiently until a sophisticated illicit market develops to replace the legitimate one, and that a state's success in regulating salvia may be related to their regulation of and enforcement of other drug prohibitions.

Scholars have recently reformulated the moral panic framework (Goode and Ben-Yehuda 1994, 2009). We employ this new framework in an evaluation of Gainesville, Florida's adoption of the anti-rave law. Our findings suggest that both individuals and groups were vital in the construction of an interest group model moral panic that led to the adoption of this law. Although researchers have utilized the moral panic framework in analyzing many social and legal changes over the past 40 years, it has also garnered much criticism. In an effort to further advance the framework, we provide several modifications to Goode and Ben-Yehuda's (2009) most recent reconceptualization and recommendations for future moral panic research.

Salvia divinorum is a new recreational drug where few studies have been conducted on its prevalence and predictors of use. Using a sample of undergraduate students, this study investigated these issues. While a small number reported experimenting with salvia, logistic regression models showed that demographics, marijuana use, and self-control are statistically significant predictors. The effect of gender on use was explained by low self-control; but the effect of marijuana use remained. Results also showed that White males who frequently smoke marijuana and have extremely low self-control are most likely to use salvia. Limitations and future research are discussed.

The recreational use of Salvia divinorum has received increased attention by media outlets and policy-makers in recent years. The vast absence of research to guide the dissemination of information has prompted this research note describing the use of this substance in a large public institution of higher education. The prevalence of Salvia divinorum is described in this context and a description of patterns of use, methods of acquisition, and a subjective estimation of continuance are proffered.

* Abbreviations: BHO — : butane hash oil THC — : tetrahydrocannabinol The practice now known as “dabbing” appears to be quickly proliferating as a fashionable way to use marijuana in the United States.1 Dabbing is the inhalation of a concentrated tetrahydrocannabinol (THC) product created through butane extraction. The use of butane hash oil (BHO) products and the modification of cannabis more generally are not new phenomena, but dabbing has recently moved from relative obscurity to the headlines, leaving cannabis aficionados, adolescents, and parents curious about its effects. Physicians and other health care professionals need to be prepared for discussions about the effects of dabbing to minimize potential harms, particularly because recent marijuana policy changes likely has facilitated youth access to “dabs.” BHO is made from cannabis and in many instances may be used to salvage less potent portions of the plant.2 Because BHO production is uncomplicated, requires few resources, and is the subject of countless instructional videos on social media Web sites, recreational users have created BHO at home in a process colloquially called “blasting.” Blasting involves passing butane through a steel or glass tube packed with dried cannabis trimmings. THC and other hydrophobic compounds in the vegetation’s trichomes dissolve within the butane; the butane–THC solution leaves the tube through a filter and is collected in a dish or tray. Because butane is very volatile, it evaporates (or is purged within a vacuum oven), leaving crystalized resins that can have a THC concentration approaching 80%. This product can take many forms depending on heat, pressure, humidity, and other factors. The form most challenging to produce … Address correspondence to John M. Stogner, PhD, Department of Criminal Justice and Criminology, University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte, NC 28223. E-mail: johnstogner{at}uncc.edu

Emerging trends in drug use and distribution / , Emerging trends in drug use and distribution / , کتابخانه دیجیتال جندی شاپور اهواز

BackgroundResearch suggests an association between frontal and temporal injury and antisocial conduct. We studied the frequency of antisocial behaviours in fronto-temporal dementia (FTD) where pathology is anterior frontal-temporal, compared with Alzheimer's disease (AD) where pathology is primarily posterior temporal-parietal.MethodThe presence of antisocial conduct was compared in 22 FTD versus 22 AD subjects. All FTD patients had anterior frontal or temporal hypoperfusion with single photon emission computed tomography, whereas those with AD had posterior temporal-parietal hypoperfusion.ResultsTen FTD and one AD subject showed antisocial behaviours, which included assault, indecent exposure, shoplifting and hit-and-run driving. Three FTD subjects were arrested. This difference was highly significant (P = 0.004).ConclusionsDegeneration of frontal and temporal lobes predisposes to antisocial behaviour. This study supports a relationship between frontal-temporal dysfunction and certain types of antisocial activities.

In order to offer more insight into the novel and emerging drug phenomenon, a series of case studies are presented in the following pages that intricately explore the recreational use, media coverage, and regulation of three emerging psychoactive substances with diverse effects and unique histories. First, a short-acting dissociative plant in the mint family, Salvia divinorum, is described as an example of an extant drug that somewhat suddenly became linked to recreational use after the natural product was chemically enhanced, mass produced, and packaged for retail sale by a handful of organizations. This drug is also an excellent example of state-led drug regulation as opposed to federal oversight. Second, the chapter examines the appearance of psychoactive synthetic stimulants marketed as “bath salts.” This category of substances received significant media attention and was quickly scheduled at the federal level in most countries. Finally, we present the recreational use of a recently synthesized research chemical that has yet to become a widespread drug of abuse. Bromo-DragonFly is a powerful and long-acting hallucinogen when taken recreationally.

Over the past two decades in particular, there has been increasing concern over a subset of psychoactive substances new on the drug scene. While some have received a substantial amount of media coverage in recent years, many of these substances are unheard of by the vast populous; in fact, only a niche group of drug users may know of their existence previous to their eventual exposure to the public. There is, however, a good base for understanding these emerging drugs as presented in this chapter. A framework is presented to better grapple with emerging drug trends given this knowledge base. This provides a solid foundation to expand on previous research while minimizing the temptation of including anecdotal and circumstantial evidence when drawing conclusions on emerging drug trends.

Introduction and Aims Until recently, synthetic cathinones marketed as ‘bath salts’ were legally sold at convenience stores and online in the USA. Media reports initiated concerns of a growing ‘bath salt’ epidemic. Despite media attention and the recent legal action banning synthetic cathinones, little is known about its prevalence or users. Design and Methods A self-report survey was administered to 2349 students in 40 randomly selected courses at a large university in the Southeastern United States. The resulting sample was 51.6% female, 68.9% white, 24.4% black, 2.8% Hispanic and 4.0% other races, with a mean age of 20.06 years and median family income of $75 000–99 999. Results Only 25 (1.07%) of the students reported using synthetic cathinones at least once. Synthetic cathinone use was found to be more common among men (1.68% vs. 0.50% of women, P = 0.005), Hispanics (4.7%) and Native Americans (4.3% vs. 0.89% of whites and 0.72% of blacks, P = 0.002), and student athletes (4.0% vs. 0.90% of non-athletes, P = 0.001), but in each of these groups, synthetic cathinones were used more rarely than marijuana (58.14%, P

Researchers commonly use a person's perception of the drug use of friends to determine the impact that peers exert on one's own behavior. Recently, there has been concern over this measure's validity. Novel drugs, which are either newly discovered drugs or existing substances only recently used for recreational purposes, may be used so infrequently that people have too few observable opportunities to accurately develop perceptions of their peer's use. Employing survey data collected in 2009 from 2,154 individuals within friendship pairs in the Southeast United States, we explore how gender affects perceptions of the infrequently used, novel drug Salvia divinorum. The study's limitations are noted.

A mixture of codeine cough syrup with alcohol and/or a soft drink known as "purple drank" has gained media attention in recent years as a drug associated with professional athletes and southern rap music. The existing research on purple drank consumption has primarily utilized samples of African Americans residing in the Houston, Texas area. This is the first scholarly study of purple drank use outside of the Houston, Texas area among a general population of young adults, and indicates that purple drank use is not limited to African American males. The findings depict higher odds of the use of purple drank among other racial and ethnic groups, males, and homosexual, bisexual, and transgender college students from urban areas.

We present a case of acute alcohol-induced Korsakoff amnesia. A severe amnestic-confabulatory syndrome characterized the early clinical status. The initial neuropsychological tests demonstrated severe learning deficits plus impaired performance on many, but not all, tests of frontal lobe function. Single-photon emission CT (SPECT) at this stage showed hypoperfusion in the orbital and medical frontal regions and the medial diencephalic area. Four months later, the patient's amnesia remained but there was no confabulation. Repeat neuropsychological tests confirmed an ongoing severe amnesia, but performance on the frontal lobe tests now was normal. Repeat SPECT showed a return to normal perfusion in the frontal brain areas but little improvement in the medial diencephalic region. These findings along with data from the clinical literature suggest that confabulation results from dysfunction of orbital and a medial frontal cortex.

Background This study aims to understand which young adults’ drinking behaviors change in the presence of happy hour specials, the ways in which they change, and whether a link exists between happy hour drinking behavior and negative outcomes. Methods Using data collected from bar-going respondents (n = 1,423) within a print survey administered to a general college sample (n = 2,349), we identify significant differences in changes in happy hour behavior between demographic groups using χ2 tests and determine whether this behavior is related to six negative alcohol-related outcomes using logistical and ordinary least squares regression models with a variety of controls, including age of onset and frequency of use. Results Women, students under 21, non-athletes, members of Greek-affiliated organizations, more affluent and unemployed students, and students living on campus were more likely to change their drinking behavior in the presence of happy hour specials. In general, the most robust predictors of negative events are gender, alcohol use frequency, age of alcohol use onset, and increasing drinking due to happy hours/bar specials. While it was linked to various negative and illegal behaviors, altered happy hour drinking was not associated with an increased likelihood of an alcohol-related arrest. Conclusions This study lends support to the idea that alcohol price specials should be regulated in an effort to reduce high consumption and alcohol-related negative consequences. Future research into the relationship between happy hour drinking and negative outcomes is necessary and should examine the impact of happy hour advertisements, different types of specials, and the timing of happy hours.