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Objective: Patients with pyogenic spondylodiscitis might present with neurological deficits with or without epidural abscess requiring spinal decompression. The aim of this study was to investigate the role of epidural abscess and spinal decompression in the treatment of patients with pyogenic Spondylodiscitis.[for full text, please go to the a.m. URL], 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Objective: The assessment criteria for successful fusion after spine surgery vary widely. While some authors content themselves with a lack of implant loosening, others request imaging evidence of bone bridge formation, e.g. on radiographs or even on computed tomography. The aim of this study was[for full text, please go to the a.m. URL], 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Objective: Implantation of a vp-shunt represents the current standard of care in hydrocephalus patients. Both combination valves implanted in this study contain a proprietary differential pressure valve, which is combined with a gravity-regulated anti-siphon device (ASD) in the proGAV (PG) valve and[for full text, please go to the a.m. URL], 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Objective: Pyogenic spondylodiscitis is associated with significant morbidity and mortality. Secondary spinal deformity may arise due to vertebral body collapse. Despite growing number of studies on the subject, there is no consensus on the threshold for 360° fusion compared to stand-alone posterior[for full text, please go to the a.m. URL], 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Objective: Cold-inducible RNA binding protein (CIRBP) is a stress induced protein which plays a key role in RNA dynamics, translational efficiency and metabolism. Recent studies have implicated CIRBP in many human diseases including several types of cancer. In tumor CIRBP promotes tumor growth by coordinating[for full text, please go to the a.m. URL], 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Objective: Up to 10% of patients with ischemic strokes develop a malignant edema. In patients with malignant cerebral infarction (MCI), early decompressive hemicraniectomy (DHC) can significantly reduce mortality. Early detection of patients developing MCI is still a challenge, since no reliable[for full text, please go to the a.m. URL], 69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie

Objective: The use of 5-aminolevulinic acid (5-ALA) fluorescence to delineate tumors tissue is an established technique for primary malignant brain tumors, less so for metastatic brain disease. Critics argue that visibility of tumor cells at resection margins may elude microscopic visualization. Therefore,[for full text, please go to the a.m. URL], 69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie

Objective: Although decompressive hemicraniectomy (DHC) significantly reduces the mortality of malignant cerebral infarction (MCI), still a high rate of moderate to severe disability is observed among the survivors. Particularly the right point in time performing DHC has not been defined yet. In this[for full text, please go to the a.m. URL], 69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie

Objective: D,L-Methadone has played a role in palliative care and is used for pain treatment in patients with cancer. Recently an increasing number of articles and TV programmes in (social) media suggested that D,L-Methadone would positively influence the clinical course of patients with high grad glioma[for full text, please go to the a.m. URL], 69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie

Objective: Malignant intramedullary tumors usually require radiation therapy which might lead to cord edema with severe neurological decline. Spinal expansile duraplasty enlarges the intradural space and might thus inhibit radiation-induced neurological deficits. The aim of this study is to evaluate[for full text, please go to the a.m. URL], 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS)