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Clinical results and some medical difficulties in ophthalmology is straight connected with repairing processes and unpredictable cellular response. The opportunity of enzyme medicine using is associated with their ability to raise the therapeutic effect in different pathological cases in clinical practice. Often because of fibrin extra production the result of the disease could be unfavourable. Searching for the treatment method which could prevent fibrin extra production is the actual ophthalmological problem. Longidaza is a conjugate of enzyme hyaluronidase with high molecular weight azoximer, and it has an opportunity to lyse extra fibrin fibres, which was produced during the inflammation process after traumatic damage, surgical treatment. The efficiency of the using of enzyme medicines is reported in cornea pathological cases, and in vitreous body pathological cases, that could be a new conservative way for treatment. The advantages of longidaza are: atraumatic injections ways; minimal side-effects; no rehabilitation period; low price. According to ambiguous in opinions it is necessary to continue to research Longidaza.

The success of the surgery performed on the urinary tract, much depends on preventing scar-sclerotic complications in the postoperative period. In this regard, an important issue is to find a path genetically based methods to prevent the development of urinary tract strictures. After performing surgical procedures on the urinary tract of a complex drug therapy by Longidaza 3000 IU in combination with magnetic-laser therapy can reduce the development of sclerotic complications in 3 times, which reduces the number of repeat surgery, and can be recommended for use in clinical practice.