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USE OF ORAL amoxicillin-clavulanic acid for 5 days was noninferior to a 10-day course of treatment among children with noncomplicated febrile urinary tract infections (UTIs), according to new research. Well-appearing [...]

EVALUATION OF TEMPERAMENT in mental health outpatients showed a significant association between the irritable temperament type and a diagnosis of bipolar I and bipolar II disorders, based on data from [...]

Use of dialectical behavior therapy significantly reduced suicide attempts in adolescents with bipolar disorder, compared with standard of care, based on data from 100 individuals aged 12-18 years. Bipolar spectrum [...]

EATING DISORDERS are a common comorbidity in patients with bipolar disorder, especially those with type II, based on data from more than 2,000 individuals. Previous research of bipolar disorder (BD) [...]

Ancestry was a significant predictor of response to lithium by adults with bipolar disorder (BPD), based on data from 172 individuals. Lithium remains the first-line treatment for BPD, but clinical [...]

COMPLEX POLYPHARMACY in patients with bipolar disorder was associated with sociodemographic and clinical features, including older age, single status, and psychiatric comorbidities, based on data from more than 500 individuals. [...]

Hospital admission for children with eating disorders approximately tripled during the COVID-19 pandemic, based on data from 85 patients. Eating disorders are common among adolescents and often require hospital admission [...]

PREGNANT WOMEN with a history of spontaneous abortion had a significantly increased risk of gestational diabetes in subsequent pregnancies, based on data from more than 100,000 women. Gestational diabetes is [...]

INDIVIDUALS WITH DEPRESSION who had high levels of C-reactive protein responded poorly to selected serotonin reuptake inhibitors, compared with those with lower CRP levels, based on data from more than [...]

FROM THE PROCEEDING OF THE NATIONAL ACADEMY OF SCIENCES Mutations in genes associated with cardiac and seizure disorders appear to be linked to sudden unexplained deaths in young children and [...]

FROM RESPIRATORY MEDICINE AND RESEARCH ALMOST ALL PATIENTS with both obstructive sleep apnea syndrome and severe asthma fell into the obesity phenotype, not the allergy phenotype, based on data from [...]

SEIZURE PHOBIA occurs in nearly one-third of people with epilepsy (PWE), but was mainly associated with variables not related to epilepsy, based on data from 69 adults. Anxiety and depression [...]

FROM THE JOURNAL OF PEDIATRICS Obesity and hypoxia at the time of hospital admission predicted more severe disease in children diagnosed with COVID-19, based on data from 281 patients at [...]

FROM THE NEW ENGLAND JOURNAL OF MEDICINE ADDING SUBCUTANEOUS nemolizumab to topical treatments for atopic dermatitis (AD)patients significantly improved their itching, compared with a placebo, in a phase 3 study [...]

FROM ARTHRITIS CARE & RESEARCH LUPUS IMAGES in medical resource materials underrepresent patients with skin of color, based on data from a review of more than 1,400 images published between [...]

Hispanic diabetes patients are significantly less likely than Black or White patients to receive preventive guideline-based care soon after diagnosis, based on data from more than 7,000 individuals. Racial and [...]

Adults with knee osteoarthritis who participated in a self-directed, web-based exercise program with automated text-message reminders and encouragement for 6 months showed significant improvement in overall knee pain and physical [...]

Cardiovascular disease risk is elevated among transgender individuals seeking gender-affirming hormone therapy, according to a retrospective study in 427 patients. Previous research suggests that the use of gender-affirming hormone therapy [...]

FROM KIDNEY WEEK 2012 Adding the renin inhibitor aliskiren standard hypertension treatment did not reduce serious cardiovascular or renal events in type 2 diabetes patients with comorbid kidney or cardiovascular [...]

FROM THE ANNUAL MEETING OF THE AMERICAN COLLEGE OF RHEUMATOLOGY CHICAGO - The shingles vaccine does not increase the risk of shingles in patients who are taking biologics for autoimmune [...]

The estimated overall rate of new HIV infections in the United States has remained stable at approximately 50,000 over the past 3 years, but infection rates increased significantly among young [...]

Women with fibromyalgia who participated in an 8-week yoga program reported significant improvements on measures of fibromyalgia symptoms and function, based on data from a pilot study of 53 women. [...]

WASHINGTON -- A contraceptive patch that has been effective for the standard 21-day cyclic regimen appears to translate seamlessly into an extended regimen, results of a pilot study suggest. Use [...]

Adding the renin inhibitor aliskiren to standard hypertension treatment in type 2 diabetes patients with comorbid kidney or cardiovascular disease did not reduce serious cardiovascular or renal events, according to [...]

FROM JAMA Adults with major depression were significantly less likely to discontinue treatment when they received telephone-administered cognitive-behavioral therapy, compared with patients who received face-to-face CBT. However, at 6 months, [...]

AT THE ANNUAL EUROPEAN CONGRESS OF RHEUMATOLOGY Ustekinumab at 45-mg and 90-mg doses significantly improved arthritis symptoms, physical function, and inflammation in adults with psoriatic arthritis, compared with placebo, after [...]

In the wake of a cholera outbreak in Haiti in 2010, Partners in Health, the Boston-based nonprofit advocacy and global health organization, developed an ambitious pilot program to vaccinate against [...]

Adults with major depression were significantly less likely to discontinue treatment when they received telephone-administered cognitive-behavioral therapy, compared with patients receiving face-to-face CBT, but those who received in-person therapy were [...]

FROM THE ANNUAL MEETING OF THE AMERICAN COLLEGE OF RHEUMATOLOGY CHICAGO - Metabolic syndrome is significantly more common in patients with psoriatic arthritis than in those with rheumatoid arthritis, based [...]

FROM THE ANNUAL MEETING OF THE AMERICAN COLLEGE OF RHEUMATOLOGY CHICAGO - The shingles vaccine does not increase the risk of shingles in patients taking biologics for autoimmune or inflammatory [...]

FROM THE ANNUAL MEETING OF THE AMERICAN COLLEGE OF GASTROENTEROLOGY NATIONAL HARBOR, MD. - Treating patients with both rosacea and small intestinal bacterial overgrowth with the drug rifaximin was associated [...]

FROM A CONGRESS OF THE INTERNATIONAL SOCIETY FOR SEXUALLY TRANSMITTED DISEASES RESEARCH QUEBEC CITY -- Most clinicians don't treat neonatal herpes according to recommendations, based on data from the Centers [...]

FROM THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY TORONTO - Children and teens with bipolar disorder had a significantly longer recovery time and more recurrences if they had comorbid [...]

FROM THE ANNUAL MEETING OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY TORONTO - Topiramate in combination with quetiapine was well tolerated in adolescents who had bipolar disorder and [...]

FROM A CONGRESS OF THE INTERNATIONAL SOCIETY FOR SEXUALLY TRANSMITTED DISEASES RESEARCH QUEBEC CITY - Most clinicians don't treat neonatal herpes according to recommendations, based on data from the Centers [...]

QUEBEC CITY--Be sure to screen men who have sex with men for gonorrhea, and don't ignore the rectum, based on data from 1,076 MSM. 'Rectal gonorrhea probably predisposes individuals to [...]

The estimated overall rate of new HIV infections in the United States has remained stable at approximately 50,000 over the past 3 years--but infection rates increased significantly among young men [...]

FROM THE ANNUAL DIGESTIVE DISEASE WEEK Gastric bypass patients are more than twice as likely as other bariatric surgery patients are to be treated for alcohol abuse post procedure, according [...]

FROM A CONGRESS OF THE INTERNATIONAL SOCIETY FOR SEXUALLY TRANSMITTED DISEASES RESEARCH QUEBEC CITY - The incidence of herpes simplex virus type 2 in the United States has remained stable [...]

NATIONAL HARBOR, MD. -- Topical diclofenac sodium 1% gel was as well tolerated as placebo, based on data from 1,426 patients with knee osteoarthritis and 783 patients with hand osteoarthritis. [...]

FROM THE ANNUAL MEETING OF THE AMERICAN ACADEMY OF PAIN MEDICINE NATIONAL HARBOR, MD. -- Fibromyalgia patients who failed to respond to pregabalin showed significant symptom improvement when milnacipran was [...]

Use of tumor necrosis factor antagonist agents significantly reduced the risk of cardiovascular events in rheumatoid arthritis patients, according to an analysis of data from more than 10,000 patients. Although [...]

Patients who received methotrexate in combination with other disease-modifying antirheumatic drugs were significantly more likely to remain on anti-tumor necrosis factor therapy than were those who received methotrexate monotherapy or [...]

Women with fibromyalgia who participated in an 8-week yoga program reported significant improvements on measures of fibromyalgia symptoms and function, based on data from a pilot study of 53 women. [...]

FROM THE JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY The constellation of risk factors known as the metabolic syndrome was associated with a 1.5-fold increase in all-cause mortality and a [...]

Cognitive-behavioral therapy significantly improved attention-deficit/hyperactivity disorder symptoms in adult patients who were already taking medication, compared with patients who used relaxation with educational support, according to data from a study [...]

WASHINGTON -- Nitrogen-containing bisphosphonates were associated with a significantly decreased prevalence of cardiovascular calcification in women older than 65 years, based on data from 3,710 women who are part of [...]

SAN FRANCISCO -- Normalization of CA 125 levels after one cycle of chemotherapy is a significant predictor of recurrence-free and overall survival in women with high-risk, early-stage epithelial ovarian cancer, [...]

NEW ORLEANS--Approximately half of children with asthma were deficient in vitamin D in a study of 99 children aged 18 and younger. Previous studies have indicated that vitamin D insufficiency [...]

ORLANDO--Daily application of 3.75% imiquimod cream with a 2-week dosing cycle was well tolerated and effective for treating actinic keratoses in adults, based on data from two studies. In current [...]