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Environmental attack has the potential to limit turbine disk durability, particularly in next generation engines which will run hotter; there is a need to understand better oxidation at potential service conditions and develop models that link microstructure to fatigue response. More efficient gas turbine engine designs will require higher operating temperatures. Turbine disks are regarded as critical flight safety components; a failure is a serious hazard. Low cycle fatigue is an important design criteria for turbine disks. Powder metallurgy alloys, like ME3, have led to major improvements in temperature performance through refractory additions (e.g. Mo,W) at the expense of environmental resistance (Al, Cr). Service conditions for aerospace disks can produce major cycle periods extending from minutes to hours and days with total service times exceeding 1,000 hours in aerospace applications. Some of the effects of service can be captured by extended exposures at elevated temperature prior to LCF testing. Some details of the work presented here have been published.