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A significant proportion of lesions of endodontic origin require treatment due to the diagnosis of odontogenic cysts and benign tumors in the maxilla and mandible. Osteomas represent common lesions, which are slow-growing and well-demarcated from the adjacent bone. Following endodontic microsurgery, osseous graft material was placed in the fill, as a Guided Tissue Regeneration procedure, in order to fill the defect and to accelerate bone regeneration. The presented case discusses the one-step treatment of a right-sided anterior mandibular osteoma following endodontic microsurgery, coupled with retrograde fill of the apex, followed by the application of Bond Apatite® material for the regeneration of the osseous defect associated with the lesion and the resulting surgery. [ABSTRACT FROM AUTHOR]

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