INFLAMMATORY BOWEL DISEASE (IBD), NAMELY CROHN DISEASE (CD) AND ULCERATIVE COLITIS (UC), IS MOST TYPICALLY DIAGNOSED IN LATE adolescence and early adulthood.1 The incidence of pediatric IBD is on the rise in many Western countries. In Finland, the incidence almost doubled from 1987 to 2003,2 and the same trend has been observed elsewhere.3–6 Primary causes of IBD or factors underlying the increasing incidence and geographic variation remain obscure.7 Symptoms of IBD, such as uncontrollable bowel function, rectal bleeding, diarrhea, abdominal pain, weight loss, fatigue, and, in CD, aphthous ulcers and fever, may be severe and may disturb sleep. Surprisingly, very few studies have investigated the quality of sleep and daytime tiredness in patients with IBD. A recent report on sleep disturbances compared adults with inactive IBD (n = 16) with patients with irritable bowel syndrome (IBS) (n = 9) and healthy control subjects (n = 7).8 Patients with IBD did not differ significantly from patients with IBS with respect to sleep parameters assessed by a single night of polysomnography and questionnaires. However, sleep quality of both patient groups was lower than that of the control group. The 3 groups did not differ with respect to daytime dysfunction.8 Another questionnaire-based study of sleep disturbances among adult patients with inactive IBD (n = 80) showed prolonged sleep latency, frequent sleep fragmentation, higher rate of using sleeping pills, decreased daytime energy, increased tiredness, and poor overall sleep quality in IBD compared with healthy control subjects (n = 15).9 In this study, patient-reported sleep quality correlated with disease severity. Of the patients with IBD, 66% assessed their sleep as poor during the active state of the disease, and 49% believed disturbed sleep affected their inflammatory disease.9 Likewise, in a study focusing on extraintestinal symptoms in adults with IBD (n = 55), patients with IBD were noted to have significantly more sleep disturbances than control subjects, and diarrhea predicted sleep disturbances in these patients.10 In all of these studies, only adult patients were included. The sample sizes were small, and population-based control groups were lacking. Data on sleep disturbances in young patients with IBD are sparse. We found only 1 preliminary study on sleep disturbances among young patients with IBD (n = 41) in Israel, published as an abstract.11 This questionnaire-based study concluded that moderate and severe sleep disturbances are frequent among young patients with IBD. No correlation was found between sleep disturbance and disease characteristics of IBD (e.g., disease type, disease activity, or medication). No precise information was given about the method of collecting data on sleep or disease activity. For other inflammatory conditions, such as juvenile rheumatoid arthritis (JRA), sleep quality and daytime tiredness have been explored in a few studies.12–16 These findings reveal that sleep is disrupted in children with JRA. For example, comparable child and parent questionnaires, the Sleep Self-Report (SSR) and the Children's Sleep Habit Questionnaire (CSHQ), were used in a retrospective study of 25 children with active JRA to assess sleep and its relationship to pain, dysfunction, and disease activity.15 Parents of patients with JRA reported significantly higher total scores on the CSHQ and on the subscales assessing nighttime waking, parasomnias, sleep anxiety, sleep-disordered breathing, and morning wakening/daytime sleepiness than did parents of healthy control subjects. However, the total score on the CSHQ did not correlate with disease severity; this was in contrast with the total score on the SSR, which correlated highly with pain but not with other arthritis-related variables.15 Lack of knowledge about the quality and quantity of sleep in pediatric patients with IBD warrants studies in these patients. Sleep disturbances may increase the risk for psychosocial symptoms or disorders such as tiredness and depression.17 Thus, more research is needed on sleep in adolescents with IBD and the association between sleep and IBD symptom severity. The first objective of the current study was to evaluate sleep problems, quality of sleep, and daytime tiredness among adolescents with IBD in comparison with population-based control subjects. The second objective was to evaluate the effect of the severity of IBD symptoms on sleep problems, quality of sleep, and daytime tiredness. This questionnaire-based study includes both parent and self-reports.