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The Stafne defect is a benign, asymptomatic, non-progressive and rare bone depression, mainly discovered by chance in the posterior mandibular region. It is described radiographically as an oval radiolucency located below the mandibular canal, in the molar region, close to the submandibular gland. Sialography is a traditional technique in the radiographic examination of salivary glands that involves the injection of an iodine-based contrast medium into the main salivary duct. The Cone Beam Computed Tomography (CBCT) is a 3D imaging technique that has modernized the dental and maxillofacial practice with its advantages such as high speed, good spatial resolution and low radiation exposure. The CBCT Sialography that consists in a 3D Sialography with cone beam offers the same benefits as traditional sialography and allows three-dimensional viewing. It is a new imaging test for an accurate anatomical study of the major salivary glands and their relationships with their environments. The aim of this report is to present a case of Stafne bone cavity containing right submandibular gland tissue, occurring in a 58-year-old man and diagnosed by using CBCT sialography.

Background The safety and immunogenicity of PfAMA1, adjuvanted with Alhydrogel® was assessed in malaria–experienced Malian adults. The malaria vaccine, PfAMA1-FVO [25-545] is a recombinant protein Pichia pastoris-expressed AMA-1 from Plasmodium falciparum FVO clone adsorbed to Alhydrogel®, the control vaccine was tetanus toxoid produced from formaldehyde detoxified and purified tetanus toxin. Methods A double blind randomized controlled phase 1 study enrolled and followed 40 healthy adults aged 18–55 years in Bandiagara, Mali, West Africa, a rural setting with intense seasonal transmission of P. falciparum malaria. Volunteers were randomized to receive either 50 µg of malaria vaccine or the control vaccine. Three doses of vaccine were given on Days 0, 28 and 56, and participants were followed for 1 year. Solicited symptoms were assessed for seven days and unsolicited symptoms for 28 days after each vaccination. Serious adverse events were assessed throughout the study. The titres of anti-AMA-1 antibodies were measured by ELISA and P. falciparum growth inhibition assays were performed. Results Commonest local solicited adverse events were the injection site pain and swelling more frequent in the PfAMA1 group. No vaccine related serious adverse events were reported. A significant 3.5-fold increase of anti-AMA-1 IgG antibodies was observed in malaria vaccine recipients four weeks after the third immunization compared to the control group. Conclusion The PfAMA1 showed a good safety profile. Most adverse events reported were of mild to moderate intensity. In addition, the vaccine induced a significant though short-lived increase in the anti-AMA1 IgG titres. Registered on www.clinicaltrials.gov with the number NCT00431808 Electronic supplementary material The online version of this article (doi:10.1186/s12936-016-1466-4) contains supplementary material, which is available to authorized users.

Background Plasmodium falciparum resistance to artemisinin has been reported in South-East Asia. Long half-life drugs are increasingly being used for malaria prevention. The potential spread of parasite resistance to these regimens is real and makes regular efficacy surveillance a priority. Methods From August to December 2004 and July to December 2005, a randomized open label trial of sulphadoxine-pyrimethamine (SP) + artesunate (AS) versus SP + amodiaquine (AQ), and SP alone, was conducted in two villages of Mali. PCR was used to distinguish new infections from recrudescent P. falciparum infections. Patients were followed for 28 days to assess treatment efficacy. Results Overall 912 children aged between six to 59 months, with uncomplicated P. falciparum malaria were recruited. Baseline characteristics were similar in the three treatment arms. Crude ACPRs were 94.9%; 98.6% and 93.5% for SP + AS; SP + AQ and SP alone arms respectively (SP + AS versus SP + AQ, p = 0.01; SP + AS versus SP, p = 0.5; SP + AQ versus SP, p = 0.001). After PCR adjustment, cACPRs were 99%; 100% and 97.2% for SP + AS; SP + AQ and SP alone arms, respectively (SP + AS versus SP + AQ, p = 0.25; SP + AS versus SP, p = 0.12; SP + AQ versus SP, p = 0.007). Conclusion Sulphadoxine-pyrimethamine + amodiaquine therapy was as efficacious as sulphadoxine-pyrimethamine + artesunate, but more efficacious than sulphadoxine-pyrimethamine alone in the treatment of uncomplicated P. falciparum malaria in Mali.

ED EPS - Supplementary Materials and Associated Data on PMCentral.; International audience; This article assesses the role of malaria and certain social determinants on primary education, especially on educational achievement in Donéguébougou, a small village in a malaria-endemic area near Bamako, Mali. Field data was collected by the authors between November 2007 and June 2008 on 227 schoolchildren living in Donéguébougou. Various malaria indicators and econometric models were used to explain the variation in cognitive abilities, teachers' evaluation scores, school progression and absences. Malaria is the primary cause of school absences. Fixed-effects estimates showed that asymptomatic malaria and the presence of falciparum malaria parasites had a direct correlation with educational achievement and cognitive performance. The evidence suggests that the correlation is causal.

Authors bring back their experience in surgery thyroïdienne patient sur192s admitted and operated in five years in tea service of General Surgery of him FALLEN Ignace Deen Conakry of. Thesis patients represented 3.13% of tea 6139 surgical interventions exercised during tea period of survey. It was about has retrospective survey of descriptive type going from January 1st, 1997 at 31 December 2001, structural one aspects epidemiological, clinic, therapeutic and histologique. Tea done operative gesture was 86 lefts loboisthmectomieseses (44.17%), 41 rights loboisthmectomieseses (21.35%), 58 thyroidectomies subtotales (30.21%), 7 thyroidectomieses total (3.65%). Tea gotten results were good in 99.48%. To slot of death has been recorded, representing 0.52%. Tea goalkeeper of tea survey was to appreciate results of surgery thyroidienne and to take out again elements of bad prognostication of this surgery in their service.

In May 2001, we conducted a descriptive transversal survey with a single data collection phase in 13 schools in Abidjan, Ivory Coast. The purpose of the study was to evaluate the awareness, attitudes, and practices of teenagers with regard to HIV/AIDS. Most respondents (66.5%) were female. Mean age was 16.32 years (range, 13 to 19 years). Most respondents stated that they had heard about AIDS and demonstrated good factual knowledge. The most frequently mentioned method of prevention was condom use (89.2%). A total of 338 (56.1%) had already experienced sexual intercourse. However most sexually active respondents stated that they did no always use condoms.

The non carious cervical lesion (NCCL) is a loss of tooth tissue at the neck of affected teeth that is unrelated to tooth decay. They are commonly encountered in clinical practice and present in a variety of forms. The purpose of this paper is to determine the prevalence of the NCCL in a Senegalese population. From 655 patients, 112 with cervical lesions were identified i.e. a global prevalence of 17.10%. The prevalence rate for abrasion was reported to be 77.70%, 12.50% for abfraction and 9.80% for erosion. Etiological factors were studied for abrasion and erosion. 54% of the patients with abrasion used their toothbrush horizontally. For erosion, only external factors were identified: consumption of acidic drinks (9 patients) or alcohol (1 patient) and professional environment (1 patient). Dentists should consider these lesions in their daily practice.

The maxillary first molar is submitted to frequent endodontic treatment and more over, it presents the highest failure rates, often in relation with his mesio-buccal root. Several studies about failures factors showed implication of root canal anatomy often in relation with the frequency of second canal. However, other failures factors, as the foramen situation, which is very important in endodontic practice, could increase the failure rate. The aim of this study was to determine the foramen situation in Senegalese people. The results showed 63.85% of excentric foramina (83 out of 130). 86% of excentric foramina were located at 1.5mm radiology apex.

This retrospective study of 118 teeth receiving root canal treatment was conducted to determine the frequence and complications of delayed root canal treatment. Teeth were categorised into prompt treatment group and delayed treatment group according to the length time of treatment; prompt treatment group was defined as a group where root canal treatment was achieved within a period of 4 months or less, and delayed treatments group, a group where period of treatment was greater than 4 months or where canals were never obturated. Two types of complications were studied: postobturation pain and fracture involving tooth extration. The results of this study have shown that 34.5% of treatments were delayed. In this group we found also a higher rate of fractures involving tooth extraction, but the difference was not significant. The results have also shown that disappearance of pain was the essential factors in the frequence of delayed treatment, but the dental chair breakdown had some responsability. As well as in the two groups, the first reason of extractions was fracture and not pain. These results emphasize the necessity of focusing the patient's motivation on the risk of losing the tooth.

This study shows and evaluates the quality of the new root canal filling and periapical healing about 24 cases of endodontic retreatment, equivalent of 7.76% of endodontic treatments done at the clinic. The main consultation purposes were pain (54.17%) and pre-prosthetic control (40.90%) on these patients. 75% of teeth were treated in a single session attempt to 45 minutes. The root canal filling is performed in 91.65% of cases, with the safe apical limit reached in 88.13% and 94.11% per apical healing toward a short term results.

After the introduction of the lateral compactage of gutta percha in endodontic clinic of OdontoStomatology Institute of Dakar in 1995; the immediate evaluation of the quality and the limit of the canal obturation due to a prospective study on 157 monoradicular teeth so be 168 canals (11 supplementary canals) has shown that 75% of canals are of type I of Vertucci and that the apical limit of security is reached within 80.25% of cases. The manual step back canal preparation (79.17%) and the technique of canal obturation by lateral compactage of gutta percha [(64.88%); Apical limit of security: 59.52%] permit to obtain a densities (95.83%) and homogeneous (79.57%) canal obturation. The indication of gutta percha compactage on monoradicular teeth (hermetic and tridimensional root canal filling) must avail to apical curved roots of lateral incisive, the use of adapted instruments in case of canines (31 mm) and apical stop cone on necrotic pulp teeth.

Coming to consult a dentist implies a toothache. Bucco-dental diseases have an insidious evolution, starting from low sound that rapidly leads to complications that are primarily manifested as pain and gingivorhage in patients. Yet there are ways of detecting these in the early stages before the stage of pain. Treating enamel decay can also be considered late if we cannot pay the price. But leaving the teeth of children decay can affect their general health throughout life. What keeps patients far from bucco-dental consultation services? Among the raisons given by 14 patients chosen at random in the Stomatology unit at CHU-Yaounde, only poverty and lack of information have drawn our attention. And to conquer this education to prevention is the solution indicated.

The objective of this study is to describe the oral hygiene habits and the status of the teeth decay of 150 senegalese students living in a university campus. The results showed that the toothbrush as mean of oral hygiene supplanted the traditional means such as "cure dents" or water rinse with finger. Results showed also a high rate decay (60%) but the CAO index remained low (2.04%). We founded an improvement of dental decay status with an increasing daily number of tooth brushing: we noted a decreasing dental plaque deposition rate, a decreasing decay rate and a CAO index remaining low until adult age.

The objective of this study is to describe the food intake and the oral hygiene habits of 150 Senegalese students living in a university campus. According to Miller, we realised a four days survey. We noted an increase of sugar drinks; tea is the most consumed drink. The results showed also that the toothbrush as means of oral hygiene supplanted the traditional means such as "cure dents" or water rinse with finger.

In this two years retrospective study the authors determined the rate of survival composite restorations and evaluated clinically the remaining restorations by the Public Health Service (P.H.S.) criteria of Ryge. These restorations were performed by students using Heliomolar composite with scotchbond 2 adhesive dentin system. Results have shown that after two years, 98 (81.67%) out of 120 restorations were present and 51.2% were still working. Clinical evaluation of the remaining restorations needed replacement mainly because of severe color mismatch. Anatomic form and marginal adaptation were well scored after two years (score Alpha or Bravo). This study has shown that composite material is a valuable and effective technology for conservative treatment of anterior teeth in Senegal to avoid tooth extractions and prosthetic. However the knowledge about the type of composite material used must be improved and the operative procedures should be more controlled.

This study was conducted to determine the incidence of pain during and after root canal treatment. Complete debridement and root canal preparation was performed in first visit. The frequency of pain was recorded and evaluated in 150 patients receiving root canal treatment. Results has shown that incidence of pain was 6.66% root canal preparation in vital teeth and 21% in non-vital teeth (necrosis). Post-obturation pain occurred in 18.75% for vital teeth and 13.15% non-vital teeth (necrosis).

This study was done to establish the prevalence of taurodontism and pyramidal molars in Senegalese people using the criteria of SCHIFFFMAN and CHANANNEL for taurodontism and the criteria of BRABANT for pyramidal molar, the first and second molars on the panoramic radiograph of 150 consecutive 15-19 year-old Senegalese people were assessed. Results have shown that taurodontism and pyramidal molars were present in 48.6% of patients (20% of teeth). Taurodontism was present in 48% (18.8% of teeth) of patients whereas prevalence of pyramidal molar was 4.6% (1.6% of teeth). Taurodontism was alone in 91.6% of case while pyramidal molar was alone in 8.6% of case.

The long-term of endodontic treatment performed by under graduated students in Dakar were assessed. The overall success rate was 83.84% Vital teeth showed better results than the non vital teeth (necrosis).

This study was done to establish the prevalence of taurodontism using the criteria of SCHIFMAN and CHANANNEL, the first and second molars on the panoramic radiograph of 150 consecutive 15-19 year-old Senegalese people were assessed. Results have shown that taurodontism was present in 48% of patients (18.8% of teeth). Taurodontism was greater in females (% compared % in male) but the difference was not significantly, it was found that was significantly greater in the maxillary and in the second molar.

This prospective study was conducted during a period of 30 days in 96 patients to determine the incidence of postobturation pain after single-visit root canal treatment in black Senegalese people. The canals of all teeth were hand-prepared and filled with zinc-oxide-eugenol paste by a Lentulo spiral paste filler. Patients were asked to categorize their pain according to the following criteria: No pain, Slight pain, Moderate pain and Severe pain. The data were analysed statically with chi-square test to determine the relationship, if any, between the pain experienced and sex, age, tooth type, apical level of root filling and number of treatment performed in the single-visit. Results show that eighteen patients experienced pain (18.75%); our results are ranging between 10% and 25% described in the literature. No significant correlation was found between postobturation pain and any other factor with the exception of the apical length of canal filling. Characteristics of postobturation pain after root canal treatment performed in single-visit in Senegalese people presents the same features as described in international papers, that is, pain appears early and analgesic therapy is effective.

Root canal therapy is usually performed in single or multiple-visit treatment. The choice of single or multiple visit depend on dentist and patient available time. In general dentistry, multiple-visit is widely chosen by dentist whereas endodontic speciality recommend single-visit. In this study we analyzed 120 root canal therapy performed by students, to determine the number of visits needed to achieve treatment from endodontic-cavity-access to root canal filling and its possible, influence in the successful rate. Results showed that globally, 60% of treatments were performed in multiple-visit. Results showed also hat 89.3% of anteriors teeth were performed in single-visit but there is a higher rate of fail: 31.78%. Nevertheless, these results do not condemn endodontic single visit therapy.