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Sir, A 54 year-old man presented with 3 years of progressive left foot drop and 4 months of proximal weakness in right leg. Hypoesthesia between left T8 and T10 levels. [...]

Keywords: Subacute combined degeneration of the cord | hyperintensity | myelopathy | vitamin B12, Case Discussion A 46 year old man, a vegetarian, presented with acute onset of paresthesia ('pins and needles' sensation) involving both hands and feet of 15 days duration. He also [...]

Vitamin [B.sub.12] deficiency may be the consequence of several pathological conditions. The most frequent neurological manifestation is the subacute combined degeneration (SCD) of the spinal cord and polyneuropathy, rarely dementia and damage of the optic nerve occur. Numbness of the limbs and trunk is an early symptom; weakness, clumsiness and spasticity, abnormal reflexes, gait ataxia develop later. MRI reveals hyperintensities involving dorsal columns of spinal cord in cervical and upper dorsal region. Timely parenteral Vit [B.sub.12] can result in complete resolution clinically as well as radiologically., Introduction Subacute combined degeneration of spinal cord is a potentially reversible cause of neuropathy if timely diagnosis and appropriate management is provided. This specific type of neuronal degeneration results from [...]