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Purpose: To assess the image quality and impact on acquisition time of a novel deep learning based T2 Dixon sequence (T2 DL ) of the spine., Methods: This prospective, single center study included n = 44 consecutive patients with a clinical indication for lumbar MRI at our university radiology department between September 2022 and March 2023. MRI examinations were performed on 1.5-T and 3-T scanners (MAGNETOM Aera and Vida; Siemens Healthineers, Erlangen, Germany) using dedicated spine coils. The MR study protocol consisted of our standard clinical protocol, including a T2 weighted standard Dixon sequence (T2 std ) and an additional T2 DL acquisition. The latter used a conventional sampling pattern with a higher parallel acceleration factor. The individual contrasts acquired for Dixon water-fat separation were then reconstructed using a dedicated research application. After reconstruction of the contrast images from k-space data, a conventional water-fat separation was performed to provide derived water images. Two readers with 6 and 4 years of experience in interpreting MSK imaging, respectively, analyzed the images in a randomized fashion. Regarding overall image quality, banding artifacts, artifacts, sharpness, noise, and diagnostic confidence were analyzed using a 5-point Likert scale (from 1 = non-diagnostic to 5 = excellent image quality). Statistical analyses included the Wilcoxon signed-rank test and weighted Cohen's kappa statistics., Results: Forty-four patients (mean age 53 years (±18), male sex: 39 %) were prospectively included. Thirty-one examinations were performed on 1.5 T and 13 examinations on 3 T scanners. A sequence was successfully acquired in all patients. The total acquisition time of T2 DL was 93 s at 1.5-T and 86 s at 3-T, compared to 235 s, and 257 s, respectively for T2 std (reduction of acquisition time: 60.4 % at 1.5-T, and 66.5 % at 3-T; p < 0.01). Overall image quality was rated equal for both sequences (median T2 DL : 5[3 -5], and median T2 std : 5 [2 -5]; p = 0.57). T2 DL showed significantly reduced noise levels compared to T2 std (5 [4 -5] versus 4 [3 -4]; p < 0.001). In addition, sharpness was rated to be significantly higher in T2 DL (5 [4 -5] versus 4 [3 -5]; p < 0.001). Although T2 DL displayed significantly more banding artifacts (5 [2 -5] versus 5 [4 -5]; p < 0.001), no significant impact on readers diagnostic confidence between sequences was noted (T2 std : 5 [2 -5], and T2 DL : 5 [3 -5]; p = 0.61). Substantial inter-reader and intrareader agreement was observed for T2 DL overall image quality (κ: 0.77, and κ: 0.8, respectively)., Conclusion: T2 DL is feasible, yields an image quality comparable to the reference standard while substantially reducing the acquisition time., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier B.V.)

· Breast MRI is an essential part of breast imaging. · The recommendations for performing breast MRI have been updated. · A table provides a compact and quick overview. More detailed comments supplement the table.. · The "classic" breast MRI can be performed based on the recommendations. Tips for special clinical questions, such as implant rupture, mammary duct pathology or local lymph node status, are included.. CITATION FORMAT: · Wenkel E, Wunderlich P, Fallenberg E et al. Aktualisierung der Empfehlungen der AG Mammadiagnostik der Deutschen Röntgengesellschaft zur Durchführung der Mamma-MRT. Fortschr Röntgenstr 2024; 196: 939 - 944., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)