7 results on '"Gorincour, G."'
Search Results
2. Prenatal prognosis of congenital diaphragmatic hernia using magnetic resonance imaging measurement of fetal lung volume.
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Gorincour, G., Bouvenot, J., Mourot, M. G., Sonigos, P., Chaumoitre, K., Garel, C., Guibaud, L., Rypens, F., Avni, F., Cassart, M., Maugey- Laulomss, B., Bouruere-Najean, B., Brunelles, F., Durand, C., and Eurin, D.
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PRENATAL care , *PRENATAL diagnosis , *OBSTETRICAL diagnosis , *MAGNETIC resonance imaging , *NEWBORN infants - Abstract
Objectives To investigate the correlation between fetal lung volume (FLV), measured with magnetic resonance imaging (MRI), and postnatal mortality in newborns with prenatally diagnosed isolated congenital diaphragmatic hernia (CDH). Methods In a 4-year prospective multi center study, 77 fetuses with isolated CDH diagnosed between 20 and 33 necks' gestation underwent fast spin-echo T2- weighted lung MRI. These MRI-FLV measurements were compared with a previously published normative curve obtained in 215 fetuses without thoracoabdominal malformations and with normal ultrasound biometric findings. FLV measurements were correlated with postnatal survival. The mean gestational age at MRI was 31.3 weeks. Results The measured/expected FLV ratio was significantly lower in the newborns with CDH who died compared with those who survived (23.6 ± 12.2 vs. 36.1 ± 13.0, P < 0.001). When the ratio was below 25%, there was a significant decrease in postnatal survival (19% vs. 40.3%, P = 0.008). Survival was significantly lower for neonates when one lung could not be seen by fetal MRI compared with those fetuses with two visible lungs on MRI (17.9% vs. 62.1%, P < 0.001). Conclusion In isolated CDH, FLV measurement by MRI is a good predictor of postnatal mortality due to pulmonary hypoplasia. [ABSTRACT FROM AUTHOR]
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- 2005
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3. Fetal magnetic resonance imaging in the prenatal diagnosis of cerebellar hemorrhage.
- Author
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Gorincour, G., Rypens, F., Lapierre, C., Costa, T., Audibert, F., Robitailles, Y., and Robitaille, Y
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PRENATAL diagnosis , *FETAL brain , *CEREBELLUM , *HEMORRHAGE , *MAGNETIC resonance imaging , *ULTRASONIC imaging - Abstract
We report the case of a fetus with a sonographic mid-gestation diagnosis of hyperechogenic cerebellum suspected to be of hemorrhagic origin on fetal brain magnetic resonance imaging (MRI). No etiological factors for fetal hemorrhage were found other than a maternal heterozygocity for factor V Leiden. Following termination of the pregnancy, autopsy confirmed the prenatal diagnosis of massive cerebellar hemorrhage without underlying vascular anomaly. As an additional tool to ultrasonography, fetal brain MRI can affirm the hemorrhagic origin of hyperechogenic cerebellar lesions, especially by showing a high signal on T1-weighted images. [ABSTRACT FROM AUTHOR]
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- 2006
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4. P232 - Diagnostic prénatal d’une fistule urétrorectale en H, à propos d’un cas
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Arnaud, A., Gorincour, G., Hery, G., Potier, A., Le Bel, S., Guys, J.M., and De Lagausie, P.
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PRENATAL diagnosis , *ANORECTAL function tests , *MEDICINE case studies , *REPORTING of diseases , *PREGNANT women , *MAGNETIC resonance imaging , *ULTRASONIC imaging - Abstract
Les malformations ano-rectales sont répandues dans le monde, mais leur diagnostic prénatal est rarement réalisé. Nous rapportons le cas d’un nouveau-né dont le diagnostic ante-natal de fistule urétro-rectale en H a permis une prise en charge adaptée. Une femme enceinte de 28 ans présente à l’échographie et l’IRM à 27 semaines d’aménorrhée (SA) une dilatation liquidienne importante du colon fœtal. À 34SA, l’IRM montre une majoration de la distension liquidienne colique sans atteinte du grêle, éliminant la diarrhée fœtale et orientant vers une fistule uro-rectale. À la naissance, l’enfant ne présente aucun trouble du transit ou urinaire. Malgré cela, nous réalisons une IRM à 6 jours qui retrouve une distension recto-sigmoidienne, sans fistule visible. Afin d’étayer notre hypothèse, une urétro-cystographie rétrograde met en évidence une fistule urétro-rectale sus-montanale. Le diagnostic est confirmé lors d’une cystoscopie, et on retrouve une sténose anale. Le nouveau-né bénéficie d’une cure chirurgicale et présente un suivi à deux ans sans complication. Devant toute dilatation liquidienne colique prénatale, il faut évoquer une fistule en H conduisant à la réalisation du bilan standard de malformation ano-rectale et d’une cystographie néonatale à la recherche de la fistule. [ABSTRACT FROM AUTHOR]
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- 2010
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5. Value of diffusion-weighted images in differentiating mid-course responders to chemotherapy for osteosarcoma compared to the histological response: preliminary results.
- Author
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Baunin, C., Schmidt, G., Baumstarck, K., Bouvier, C., Gentet, J., Aschero, A., Ruocco, A., Bourlière, B., Gorincour, G., Desvignes, C., Colavolpe, N., Bollini, G., Auqier, P., and Petit, P.
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MAGNETIC resonance imaging , *OSTEOSARCOMA , *CANCER chemotherapy , *DIAGNOSTIC imaging , *CANCER in adolescence , *CANCER prognosis , *THERAPEUTICS - Abstract
Background: Preoperative diffusion-weighted MRI (DW-MRI) has been described as an efficient method to differentiate good and poor responders to chemotherapy in osteosarcoma patients. A DW-MRI performed earlier during treatment could be helpful in monitoring chemotherapy. Objective: To assess the accuracy of DW-MRI in evaluating response to chemotherapy in the treatment of osteosarcoma, more specifically at mid-course of treatment. Materials and methods: This study was carried out on a prospective series of adolescents treated for long-bone osteosarcoma. MR examinations were performed at diagnosis (MRI-1), at mid-course of chemotherapy (MRI-2), and immediately before surgery (MRI-3). A DW sequence was performed using diffusion gradients of b0 and b900. The apparent diffusion coefficients (ADC1, ADC2, ADC3, respectively), their differentials (ADC2 − ADC1 and ADC3 − ADC1), and their variation (ADC2 − ADC1/ADC1 and ADC3 − ADC1/ADC1) were calculated for each of these three time points. Results: Fifteen patients were included. Patients with no increase in ADC showed a poor response to chemotherapy on their histology results. At mid-course, the three calculated values were significantly different between good and poor responders. ADC2 − ADC1 enabled us to detect, with 100% specificity, four out of seven of the poor responders. There was no significant difference in the values at MRI-3 between the two groups. Conclusion: DW-MRI performed both at baseline and mid-course of neoadjuvant chemotherapy is an efficient method to predict further histological response of osteosarcoma. This method could be used as an early prognostic factor to monitor preoperative chemotherapy. [ABSTRACT FROM AUTHOR]
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- 2012
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6. Magnetic resonance imaging in the prenatal diagnosis of congenital diarrhea.
- Author
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Colombani, M., Ferry, M., Toga, C., Lacroze, V., Rubesova, E., Barth, R. A., Cassart, M., and Gorincour, G.
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MAGNETIC resonance imaging , *FETAL ultrasonic imaging , *PRENATAL diagnosis , *DIAGNOSIS of diarrhea , *MEDICAL imaging systems , *AMNIOTIC liquid , *FECES examination - Abstract
The article presents a study which evaluates the role of magnetic resonance imaging (MRI) and prenatal ultrasound in the diagnosis of congenital diarrhea in fetuses. It says that after evaluating the MRI examinations and fetal ultrasound of four fetuses, the provisional diagnosis was compared with the amniotic fluid biochemistry, then with the neonatal stool characteristics. The results show that the gathering of MRI findings provides an accurate prenatal diagnosis of congenital diarrhea.
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- 2010
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7. P167 - Diagnostic prénatal de malrotation intestinale en IRM fœtale
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Colombani, M., Ruocco-Angari, A., Bourlière-Najean, B., Aschero, A., Zeidan, S., Desvignes, C., Colavolpe, N., Devred, P., De Lagausie, P., Philip, N., Petit, P., and Gorincour, G.
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ABDOMINAL diseases , *PRENATAL diagnosis , *RETROSPECTIVE studies , *MAGNETIC resonance imaging , *PEDIATRIC therapy , *DATABASES , *MEDICINE case studies , *THERAPEUTICS - Abstract
Objectif: Étudier la capacité de l’IRM fœtale de détecter une malrotation intestinale. Matériel et Méthodes: Étude rétrospective sur 5 ans de notre base de données d’IRM fœtales non cérébrales. Résultats: Quatre cent une IRM fœtales furent analysées. Dans 34 cas (8,5%), le jéjunum proximal était considéré en position anormale, càd ailleurs que dans le flanc gauche sous l’estomac sur les séquences pondérées en T2. Dans 22 cas (65%), le jéjunum était situé dans l’hémi-thorax gauche dans le cadre d’une hernie diaphragmatique gauche (groupe A). Dans 7 cas (20%) il était en position extra-abdominale dans le cadre d’un laparoschisis (group B). Dans 5 cas (15%) il était anormalement situé dans l’abdomen, en position médiane ou dans le flanc droit, avec un estomac en position normale (group C). Tous les cas des groupes A et B ont été confirmées en période post-natale ou à l’autopsie. Dans 4 cas du groupe C (syndrome de Prune-Belly, poche colonique, atrésie digestive, cardiopathie) la malrotation n’était pas suspectée en échographie et était confirmée après la naissance. Dans le dernier cas, l’intestin était refoulé à droite par une duplication digestive géante, et le TOGD post-natal était normal. Conclusion: Grâce à son excellente résolution en contraste en pondération T2, l’IRM fœtale identifie avec précision une position anormale du jéjunum, en dehors de toute suspicion échographique, avec une excellente corrélation postnatale. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
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