13 results on '"De Lazzari M"'
Search Results
2. Appropriate use criteria for cardiovascular MRI: SIC - SIRM position paper Part 2 (myocarditis, pericardial disease, cardiomyopathies and valvular heart disease).
- Author
-
Francone M, Aquaro GD, Barison A, Castelletti S, de Cobelli F, de Lazzari M, Esposito A, Focardi M, di Renzi P, Indolfi C, Lanzillo C, Lovato L, Maestrini V, Mercuro G, Natale L, Mantini C, Polizzi G, Rabbat M, Secchi F, Secinaro A, di Cesare E, and Pontone G
- Subjects
- Data Accuracy, Humans, Italy, Prognosis, Quality Improvement, Societies, Medical, Cardiology methods, Cardiology standards, Cardiology trends, Cardiomyopathies diagnosis, Heart Valve Diseases diagnosis, Magnetic Resonance Imaging, Cine methods, Myocarditis diagnosis, Pericarditis diagnosis, Radiology methods, Radiology standards, Radiology trends
- Abstract
Cardiovascular magnetic resonance (CMR) has emerged as an accurate diagnostic technique for the evaluation of patients with cardiac disease in the majority of clinical settings, thanks to an established additional diagnostic and prognostic value. This document has been developed by a joined group of experts of the Italian Society of Cardiology (SIC) and Italian Society of Radiology (SIRM) to provide a summary about the current state of technology and clinical applications of CMR, to improve the clinical diagnostic pathways and to promote its inclusion in clinical practice. The writing committee consisted of members and experts of both societies in order to develop a more integrated approach in the field of cardiac imaging. This section 2 will cover myocarditis, pericardial disease, cardiomyopathies and valvular heart disease., (Copyright © 2021 Italian Federation of Cardiology - I.F.C. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
3. Predictors of Left Ventricular Scar Using Cardiac Magnetic Resonance in Athletes With Apparently Idiopathic Ventricular Arrhythmias.
- Author
-
Crescenzi C, Zorzi A, Vessella T, Martino A, Panattoni G, Cipriani A, De Lazzari M, Perazzolo Marra M, Fusco A, Sciarra L, Sperandii F, Guerra E, Tranchita E, Fossati C, Pigozzi F, Sarto P, Calò L, and Corrado D
- Subjects
- Adult, Athletes statistics & numerical data, Cicatrix physiopathology, Death, Sudden, Cardiac etiology, Death, Sudden, Cardiac prevention & control, Echocardiography methods, Electrocardiography, Ambulatory methods, Exercise Test methods, Exercise Test statistics & numerical data, Female, Humans, Male, Predictive Value of Tests, Sports Medicine methods, Cicatrix diagnostic imaging, Heart Ventricles diagnostic imaging, Heart Ventricles pathology, Magnetic Resonance Imaging, Cine methods, Magnetic Resonance Imaging, Cine statistics & numerical data, Tachycardia, Ventricular complications, Tachycardia, Ventricular diagnosis, Tachycardia, Ventricular physiopathology, Ventricular Premature Complexes complications, Ventricular Premature Complexes diagnosis, Ventricular Premature Complexes physiopathology
- Abstract
Background In athletes with ventricular arrhythmias (VA) and otherwise unremarkable clinical findings, cardiac magnetic resonance (CMR) may reveal concealed pathological substrates. The aim of this multicenter study was to evaluate which VA characteristics predicted CMR abnormalities. Methods and Results We enrolled 251 consecutive competitive athletes (74% males, median age 25 [17-39] years) who underwent CMR for evaluation of VA. We included athletes with >100 premature ventricular beats/24 h or ≥1 repetitive VA (couplets, triplets, or nonsustained ventricular tachycardia) on 12-lead 24-hour ambulatory ECG monitoring and negative family history, ECG, and echocardiogram. Features of VA that were evaluated included number, morphology, repetitivity, and response to exercise testing. Left-ventricular late gadolinium-enhancement was documented by CMR in 28 (11%) athletes, mostly (n=25) with a subepicardial/midmyocardial stria pattern. On 24-hour ECG monitoring, premature ventricular beats with multiple morphologies or with right-bundle-branch-block and intermediate/superior axis configuration were documented in 25 (89%) athletes with versus 58 (26%) without late gadolinium-enhancement ( P <0.001). More than 3300 premature ventricular beats were recorded in 4 (14%) athletes with versus 117 (53%) without positive CMR ( P <0.001). At exercise testing, nonsustained ventricular tachycardia occurred at peak of exercise in 8 (29%) athletes with late gadolinium-enhancement (polymorphic in 6/8, 75%) versus 17 athletes (8%) without late gadolinium-enhancement ( P =0.002), ( P <0.0001). At multivariable analysis, all 3 parameters independently correlated with CMR abnormalities. Conclusions In athletes with apparently idiopathic VA, simple characteristics such as number and morphology of premature ventricular beats on 12-lead 24-hour ambulatory ECG monitoring and response to exercise testing predicted the presence of concealed myocardial abnormalities on CMR. These findings may help cost-effective CMR prescription.
- Published
- 2021
- Full Text
- View/download PDF
4. Predictive value of exercise testing in athletes with ventricular ectopy evaluated by cardiac magnetic resonance.
- Author
-
Cipriani A, Zorzi A, Sarto P, Donini M, Rigato I, Bariani R, De Lazzari M, Pilichou K, Thiene G, Iliceto S, Basso C, Corrado D, Perazzolo Marra M, and Bauce B
- Subjects
- Adolescent, Adult, Echocardiography, Electrocardiography, Ambulatory, Female, Humans, Italy epidemiology, Male, Middle Aged, Prevalence, Retrospective Studies, Risk Factors, Ventricular Premature Complexes epidemiology, Ventricular Premature Complexes physiopathology, Young Adult, Athletes, Exercise Test methods, Magnetic Resonance Imaging, Cine methods, Ventricular Premature Complexes diagnosis
- Abstract
Background: Exercise-induced ventricular arrhythmias (EIVA) in young athletes raise the suspicion of an underlying heart disease at risk of sudden death., Objective: We aimed to assess the prevalence and determinants of abnormal cardiac magnetic resonance (CMR) findings in athletes referred for EIVA vs non-EIVA with negative or inconclusive echocardiography., Methods: We performed CMR in a consecutive series of athletes aged 15-50 years referred for frequent (>500 per day) or repetitive premature ventricular beats. Clinical and CMR findings were compared between athletes with EIVA and those with non-EIVA, and predictors of abnormal CMR were assessed., Results: We included 36 athletes with EIVA (median age 25 years; 27 (75%) males) and 24 with non-EIVA (median age 17 years; 18 (75%) males). CMR revealed cardiac abnormalities in 20 athletes with EIVA (56%) and in 5 with non-EIVA (21%) (P = .004). In particular, left ventricular late gadolinium enhancement was identified in 17 athletes with EIVA (47%) and in 3 with non-EIVA (13%) (P = .006), mostly with a nonischemic pattern. Predictors of abnormal CMR were T-wave inversion on electrocardiography (ECG) (odds ratio [OR] 5.2; 95% confidence interval [CI] 1.0-27.1; P = .05), complex ventricular arrhythmias on 24-hour ambulatory ECG monitoring (OR 4.5; 95% CI 1.1-18.7; P = .04), and complex EIVA with a right bundle branch block or polymorphic morphology on exercise testing (OR 5.3; 95% CI 1.4-19.4; P = .01)., Conclusion: Pathological myocardial substrates on CMR were observed significantly more often in athletes with EIVA than in those with non-EIVA. Repolarization abnormalities on baseline ECG and complex EIVA with a right bundle branch block or polymorphic morphology identified the subgroup of athletes with the highest probability of CMR abnormalities., (Copyright © 2018 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.)
- Published
- 2019
- Full Text
- View/download PDF
5. Diagnostic value and prognostic implications of early cardiac magnetic resonance in survivors of out-of-hospital cardiac arrest.
- Author
-
Zorzi A, Susana A, De Lazzari M, Migliore F, Vescovo G, Scarpa D, Baritussio A, Tarantini G, Cacciavillani L, Giorgi B, Basso C, Iliceto S, Bucciarelli Ducci C, Corrado D, and Perazzolo Marra M
- Subjects
- Adult, Aged, Coronary Angiography, Coronary Artery Disease complications, Coronary Artery Disease diagnosis, Coronary Artery Disease mortality, Female, Follow-Up Studies, Humans, Incidence, Italy epidemiology, Male, Middle Aged, Out-of-Hospital Cardiac Arrest epidemiology, Out-of-Hospital Cardiac Arrest etiology, Prognosis, Reproducibility of Results, Retrospective Studies, Survival Rate trends, Time Factors, Early Diagnosis, Magnetic Resonance Imaging, Cine methods, Myocardium pathology, Out-of-Hospital Cardiac Arrest diagnosis
- Abstract
Background: In patients who survived out-of-hospital cardiac arrest (OHCA), it is crucial to establish the underlying cause and its potential reversibility., Objective: The purpose of this study was to assess the incremental diagnostic and prognostic role of early cardiac magnetic resonance (CMR) in survivors of OHCA., Methods: Among 139 consecutive OHCA patients, the study enrolled 44 patients (median age 43 years; 84% male) who underwent coronary angiography and CMR ≤7 days after admission. The CMR protocol included T2-weighted sequences for myocardial edema and late gadolinium enhancement (LGE) sequences for myocardial fibrosis., Results: Coronary angiography identified obstructive coronary artery disease in 18 of 44 patients in whom CMR confirmed the diagnosis of ischemic heart disease by demonstrating subendocardial or transmural LGE. The presence of myocardial edema allowed differentiation between acute myocardial ischemia (n = 12) and postinfarction myocardial scar (n = 6). Among the remaining 26 patients without obstructive coronary artery disease, CMR in 19 (73%) showed dilated cardiomyopathy in 5, myocarditis in 4, mitral valve prolapse associated with LGE in 3, ischemic scar in 2, idiopathic nonischemic scar in 2, arrhythmogenic cardiomyopathy in 1, hypertrophic cardiomyopathy in 1, and takotsubo cardiomyopathy in 1. In this subgroup of 26 patients, 6 (23%) had myocardial edema. During mean follow-up of 36 ± 17 months, all 18 patients with myocardial edema had an uneventful outcome, whereas 9 of 26 (35%) without myocardial edema experienced sudden arrhythmic death (n = 1), appropriate defibrillator interventions (n = 5), and nonarrhythmic death (n = 3; P = .006)., Conclusion: In survivors of OHCA, early CMR with a comprehensive tissue characterization protocol provided additional diagnostic and prognostic value. The identification of myocardial edema was associated with a favorable long-term outcome., (Copyright © 2018 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.)
- Published
- 2018
- Full Text
- View/download PDF
6. Clinical recommendations of cardiac magnetic resonance, Part I: ischemic and valvular heart disease: a position paper of the working group 'Applicazioni della Risonanza Magnetica' of the Italian Society of Cardiology.
- Author
-
Aquaro GD, Di Bella G, Castelletti S, Maestrini V, Festa P, Ait-Ali L, Masci PG, Monti L, di Giovine G, De Lazzari M, Cipriani A, Guaricci AI, Dellegrottaglie S, Pepe A, Marra MP, and Pontone G
- Subjects
- Cardiology economics, Consensus, Contrast Media administration & dosage, Cost-Benefit Analysis, Health Care Costs, Heart Valve Diseases economics, Heart Valve Diseases physiopathology, Heart Valve Diseases therapy, Humans, Magnetic Resonance Imaging, Cine economics, Myocardial Ischemia economics, Myocardial Ischemia physiopathology, Myocardial Ischemia therapy, Predictive Value of Tests, Prognosis, Reproducibility of Results, Severity of Illness Index, Cardiology standards, Heart Valve Diseases diagnostic imaging, Magnetic Resonance Imaging, Cine standards, Myocardial Ischemia diagnostic imaging
- Abstract
Cardiac magnetic resonance (CMR) has emerged as a reliable and accurate diagnostic tool for the evaluation of patients with cardiac disease in several clinical settings and with proven additional diagnostic and prognostic value compared with other imaging modalities. This document has been developed by the working group on the 'application of CMR' of the Italian Society of Cardiology to provide a perspective on the current state of technical advances and clinical applications of CMR and to inform cardiologists on how to implement their clinical and diagnostic pathways with the inclusion of this technique in clinical practice. The writing committee consisted of members of the working group of the Italian Society of Cardiology and two external peer reviewers with acknowledged experience in the field of CMR.
- Published
- 2017
- Full Text
- View/download PDF
7. Relationship between T-wave inversion and transmural myocardial edema as evidenced by cardiac magnetic resonance in patients with clinically suspected acute myocarditis: clinical and prognostic implications.
- Author
-
De Lazzari M, Zorzi A, Baritussio A, Siciliano M, Migliore F, Susana A, Giorgi B, Lacognata C, Iliceto S, Perazzolo Marra M, and Corrado D
- Subjects
- Acute Disease, Adult, Chronic Disease, Female, Humans, Male, Middle Aged, Reproducibility of Results, Sensitivity and Specificity, Edema, Cardiac complications, Edema, Cardiac diagnosis, Electrocardiography methods, Magnetic Resonance Imaging, Cine methods, Myocarditis complications, Myocarditis diagnosis
- Abstract
Background: The pathophysiologic mechanisms and the prognostic meaning of electrocardiographic (ECG) T-wave inversion (TWI) occurring in a subgroup of patients with clinically suspected acute myocarditis remain to be elucidated. Contrast-enhanced cardiac magnetic resonance (CMR) offers the potential to identify myocardial tissue changes such as edema and/or fibrosis which may underlie TWI., Methods and Results: We studied 76 consecutive patients (median age 34years) with clinically suspected acute myocarditis, using a comprehensive CMR protocol which included T2 weighted sequences for myocardial edema. At the time of CMR, TWI was observed in 21 (27%) patients. There was a statistically significant association of TWI with the median number of left ventricular (LV) segments showing both any pattern of myocardial edema (transmural and non-transmural) [5 (3-7) vs. 3 (2-4); p=0.015] and myocardial late-gadolinium-enhancement [4 (3-7) vs. 3 (2-4); p=0.002]. Transmural myocardial edema involving ≥2 LV segments was found in 17/21 (81%) patients with TWI versus 13/55 (24%) patients without TWI (p<0.001) and remained the only independent predictor of TWI at multivariable analysis (OR=9.96; 95%CI=2.71-36.6; p=0.001). Overall, topographic concordance between the location of TWI across the ECG leads and the regional distribution of transmural myocardial edema was 88%. There was no association between acute TWI and reduced LV ejection fraction (<55%) at 6-months of follow-up., Conclusions: This is the first study to demonstrate an association between LV transmural myocardial edema as evidenced by CMR sequences and TWI in clinically suspected acute myocarditis. As an expression of reversible myocardial edema, development of TWI during the acute disease phase was not a predictor of LV systolic dysfunction at follow-up., (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Published
- 2016
- Full Text
- View/download PDF
8. Arrhythmogenic right ventricular cardiomyopathy. Contribution of cardiac magnetic resonance imaging to the diagnosis.
- Author
-
Perazzolo Marra M, Rizzo S, Bauce B, De Lazzari M, Pilichou K, Corrado D, Thiene G, Iliceto S, and Basso C
- Subjects
- Arrhythmogenic Right Ventricular Dysplasia complications, Diagnosis, Differential, Humans, Ventricular Dysfunction, Right etiology, Arrhythmogenic Right Ventricular Dysplasia diagnosis, Image Interpretation, Computer-Assisted methods, Magnetic Resonance Imaging, Cine methods, Stroke Volume, Ventricular Dysfunction, Right diagnosis
- Abstract
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited disease of the heart muscle, mostly due to genetically defective desmosomal proteins. The disease is characterized by fibrofatty replacement leading to ventricular arrhythmias and sudden death in young people and athletes. There is no single clinical gold standard examination for making a definitive diagnosis. The diagnosis is based on multiple parameters, including: (1) global or regional dysfunction and structural alteration of the right ventricle demonstrated on imaging; (2) tissue characterization by endomyocardial biopsy; (3) repolarization and (4) depolarization electrocardiographic abnormalities; (5) arrhythmias; and (6) family history. The so-called phenocopies must be included in the differential diagnosis, always taking into account that there is no single criterion sufficiently specific for a reliable diagnosis of ARVC. Contrast-enhanced cardiac magnetic resonance imaging (CE-CMR) is not yet included in the revised diagnostic criteria, although this is the only imaging modality able to depict fibrosis as late gadolinium enhancement (LGE) deposition. This review analyzes the role of CMR imaging in the diagnostic work-up of ARVC. The lack of specific diagnostic criteria contributes to the under-recognition of the nonclassic variants of ARVC, i.e., dominant or isolated left ventricular disease.
- Published
- 2015
- Full Text
- View/download PDF
9. Impact of the presence and amount of myocardial fibrosis by cardiac magnetic resonance on arrhythmic outcome and sudden cardiac death in nonischemic dilated cardiomyopathy.
- Author
-
Perazzolo Marra M, De Lazzari M, Zorzi A, Migliore F, Zilio F, Calore C, Vettor G, Tona F, Tarantini G, Cacciavillani L, Corbetti F, Giorgi B, Miotto D, Thiene G, Basso C, Iliceto S, and Corrado D
- Subjects
- Adult, Aged, Cardiomyopathy, Dilated diagnosis, Cardiomyopathy, Dilated physiopathology, Death, Sudden, Cardiac epidemiology, Female, Fibrosis complications, Fibrosis diagnosis, Humans, Incidence, Italy epidemiology, Male, Middle Aged, Predictive Value of Tests, Prognosis, Risk Factors, Survival Rate trends, Tachycardia, Ventricular diagnosis, Tachycardia, Ventricular therapy, Treatment Outcome, Cardiomyopathy, Dilated complications, Death, Sudden, Cardiac etiology, Defibrillators, Implantable, Magnetic Resonance Imaging, Cine methods, Myocardium pathology, Tachycardia, Ventricular complications, Ventricular Function, Left physiology
- Abstract
Background: Current risk stratification for sudden cardiac death (SCD) in nonischemic dilated cardiomyopathy (NIDC) relies on left ventricular (LV) dysfunction, a poor marker of ventricular electrical instability. Contrast-enhanced cardiac magnetic resonance has the ability to accurately identify and quantify ventricular myocardial fibrosis (late gadolinium enhancement [LGE])., Objective: To evaluate the impact of the presence and amount of myocardial fibrosis on arrhythmogenic risk prediction in NIDC., Methods: One hundred thirty-seven consecutive patients with angiographically proven NIDC were enrolled for this study. All patients were followed up for a combined arrhythmic end point including sustained ventricular tachycardia (VT), appropriate implantable cardioverter-defibrillator (ICD) intervention, ventricular fibrillation (VF), and SCD., Results: LV-LGE was identified in 76 (55.5%) patients. During a median follow-up of 3 years, the combined arrhythmic end point occurred in 22 (16.1%) patients: 8 (5.8%) sustained VT, 9 (6.6%) appropriate ICD intervention, either against VF (n = 5; 3.6%) or VT (n = 4; 2.9%), 3 (2.2%) aborted SCD, and 2 (1.5%) died suddenly. Kaplan-Meier analysis revealed a significant correlation between the LV-LGE presence (not the amount and distribution) and malignant arrhythmic events (P < .001). In univariate Cox regression analysis, LV-LGE (hazard ratio [HR] 4.17; 95% confidence interval [CI] 1.56-11.2; P = .005) and left bundle branch block (HR 2.43; 95% CI 1.01-5.41; P = .048) were found to be associated with arrhythmias. In multivariable analysis, the presence of LGE was the only independent predictor of arrhythmias (HR 3.8; 95% CI 1.3-10.4; P = .01)., Conclusions: LV-LGE is a powerful and independent predictor of malignant arrhythmic prognosis, while its amount and distribution do not provide additional prognostic value. Contrast-enhanced cardiac magnetic resonance may contribute to identify candidates for ICD therapy not fulfilling the current criteria based on left ventricular ejection fraction., (Copyright © 2014 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
10. Cardiac magnetic resonance features of biopsy-proven endomyocardial diseases.
- Author
-
Perazzolo Marra M, Thiene G, Rizzo S, De Lazzari M, Carturan E, Tona F, Caforio AL, Cacciavillani L, Marcolongo R, Tarantini G, Corbetti F, Iliceto S, and Basso C
- Subjects
- Adult, Biopsy, Female, Fibrosis, Humans, Male, Necrosis, Predictive Value of Tests, Prognosis, Cardiomyopathies pathology, Hypereosinophilic Syndrome pathology, Magnetic Resonance Imaging, Cine, Myocarditis pathology, Myocardium pathology
- Published
- 2014
- Full Text
- View/download PDF
11. Apicobasal gradient of left ventricular myocardial edema underlies transient T-wave inversion and QT interval prolongation (Wellens' ECG pattern) in Tako-Tsubo cardiomyopathy.
- Author
-
Perazzolo Marra M, Zorzi A, Corbetti F, De Lazzari M, Migliore F, Tona F, Tarantini G, Iliceto S, and Corrado D
- Subjects
- Aged, Chi-Square Distribution, Contrast Media, Echocardiography, Electrocardiography, Female, Humans, Male, Edema, Cardiac physiopathology, Magnetic Resonance Imaging, Cine methods, Takotsubo Cardiomyopathy physiopathology, Ventricular Dysfunction, Left physiopathology
- Abstract
Background: Tako-Tsubo cardiomyopathy (TTC) presents with chest pain, ST-segment elevation followed by T-wave inversion and QT interval prolongation (Wellens' electrocardiographic [ECG] pattern), and left ventricular dysfunction, which may mimic an acute coronary syndrome., Objective: To assess the pathophysiologic basis of the Wellens' ECG pattern in TTC by characterization of underlying myocardial changes by using cardiac magnetic resonance (CMR)., Methods: The study population included 20 consecutive patients with TTC (95% women; mean age 65.3 ± 10.4 years) who underwent CMR studies both in the initial phase and after 3-month follow-up by using a protocol that included cine images, T2-weighted sequences for myocardial edema, and post-contrast sequences for late gadolinium enhancement. Quantitative ECG indices of repolarization, such as maximal amplitude of negative T waves, sum of the amplitudes of negative T waves, and maximum corrected QT interval (QTc max), were correlated to CMR findings., Results: At the time of initial CMR study, there was a significant linear correlation between the apicobasal ratio of T2-weighted signal intensity for myocardial edema and the maximal amplitude of negative T waves (ρ = 0.498; P = .02), sum of the amplitudes of negative T waves (ρ = 0.483; P = .03), and maximum corrected QT interval (ρ = 0.520; P = .02). Repolarization indices were unrelated to either late gadolinium enhancement or quantitative cine parameters. Wellens' ECG abnormalities and myocardial edema showed a parallel time course of development and resolution on initial and follow-up CMR studies., Conclusions: Our study results show that the ischemic-like Wellens' ECG pattern in TTC coincides and quantitatively correlates with the apicobasal gradient of myocardial edema as evidenced by using CMR. Dynamic negative T waves and QTc prolongation are likely to reflect the edema-induced transient inhomogeneity and dispersion of repolarization between apical and basal left ventricular regions., (Copyright © 2013 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF
12. Appropriate use criteria for cardiovascular MRI: SIC - SIRM position paper Part 2 (myocarditis, pericardial disease, cardiomyopathies and valvular heart disease)
- Author
-
Gianluca Pontone, Cesare Mantini, Aurelio Secinaro, Marco Francone, Mark G. Rabbat, Gesualdo Polizzi, Luigi Natale, Antonio Esposito, Chiara Lanzillo, Viviana Maestrini, Andrea Barison, Francesco Secchi, Marta Focardi, Ciro Indolfi, Giuseppe Mercuro, Giovanni Donato Aquaro, Ernesto Di Cesare, Luigi Lovato, Manuel De Lazzari, Francesco De Cobelli, Silvia Castelletti, Paolo Renzi, Francone, M., Aquaro, G. D., Barison, A., Castelletti, S., de Cobelli, F., de Lazzari, M., Esposito, A., Focardi, M., di Renzi, P., Indolfi, C., Lanzillo, C., Lovato, L., Maestrini, V., Mercuro, G., Natale, L., Mantini, C., Polizzi, G., Rabbat, M., Secchi, F., Secinaro, A., di Cesare, E., and Pontone, G.
- Subjects
medicine.medical_specialty ,Myocarditis ,Cardiac magnetic resonance ,Cardiology ,Heart Valve Diseases ,Magnetic Resonance Imaging, Cine ,Disease ,030204 cardiovascular system & hematology ,Guideline ,Appropriate Use Criteria ,cardiac magnetic resonance ,03 medical and health sciences ,0302 clinical medicine ,Medical ,Medicine ,Humans ,Pericarditis ,030212 general & internal medicine ,Intensive care medicine ,Cardiac imaging ,Societies, Medical ,Pericardial disease ,medicine.diagnostic_test ,business.industry ,valvular heart disease ,Magnetic resonance imaging ,General Medicine ,medicine.disease ,Prognosis ,Magnetic Resonance Imaging ,Quality Improvement ,radiology ,Data Accuracy ,Italy ,Cine ,cardiology ,cardiovascular system ,Radiology ,Cardiomyopathies ,Position paper ,Cardiology and Cardiovascular Medicine ,business ,Societies ,guideline - Abstract
Cardiovascular magnetic resonance (CMR) has emerged as an accurate diagnostic technique for the evaluation of patients with cardiac disease in the majority of clinical settings, thanks to an established additional diagnostic and prognostic value. This document has been developed by a joined group of experts of the Italian Society of Cardiology (SIC) and Italian Society of Radiology (SIRM) to provide a summary about the current state of technology and clinical applications of CMR, to improve the clinical diagnostic pathways and to promote its inclusion in clinical practice. The writing committee consisted of members and experts of both societies in order to develop a more integrated approach in the field of cardiac imaging. This section 2 will cover myocarditis, pericardial disease, cardiomyopathies and valvular heart disease.
- Published
- 2021
13. The alcohol-induced cardiomyopathy: A cardiovascular magnetic resonance characterization
- Author
-
Gerry Carr-White, Pier Giorgio Masci, Giulia De Angelis, Gaetano Nucifora, Clint Asher, Jessica Artico, Martina Perazzolo Marra, Lorenzo Pagnan, Manuel Belgrano, Silvia Pica, Manuel De Lazzari, Marco Merlo, Aldostefano Porcari, Antonio Cannatà, Massimo Lombardi, Antonio De Luca, Amedeo Chiribiri, Gianfranco Sinagra, Giancarlo Vitrella, Artico, J., Merlo, M., Asher, C., Cannata, A., Masci, P. G., De Lazzari, M., Pica, S., De Angelis, G., Porcari, A., Vitrella, G., De Luca, A., Belgrano, M., Pagnan, L., Chiribiri, A., Marra, M. P., Sinagra, G., Nucifora, G., Lombardi, M., and Carr-White, G.
- Subjects
Cardiomyopathy, Dilated ,Male ,medicine.medical_specialty ,Magnetic Resonance Spectroscopy ,Cardiac magnetic resonance ,Cardiomyopathy ,medicine.medical_treatment ,Left ,Dilated cardiomyopathy ,Magnetic Resonance Imaging, Cine ,Contrast Media ,Predictive Value of Test ,Gadolinium ,Alcoholic cardiomyopathy ,Late gadolinium enhancement ,Ventricular Function, Left ,Predictive Value of Tests ,Internal medicine ,Dilated ,Medicine ,Humans ,Ventricular Function ,cardiovascular diseases ,Alcohol-induced ,Stroke Volume ,Cardiomyopathy, Alcoholic ,Heart transplantation ,Ejection fraction ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,musculoskeletal system ,medicine.disease ,Alcoholic ,Magnetic Resonance Imaging ,Cine ,cardiovascular system ,Cardiology ,Cardiology and Cardiovascular Medicine ,business ,Human - Abstract
Background: Alcoholic cardiomyopathy(ACM) is part of the non-ischaemic dilated cardiomyopathy(NI-DCM) spectrum. Little is known about cardiovascular magnetic resonance(CMR) features in ACM patients. The aim of this study is to describe CMR findings and their prognostic impact in ACM patients. Methods: Consecutive ACM patients evaluated in five referral CMR centres from January 2005 to December 2018 were enrolled. CMR findings and their prognostic value were compared to idiopathic NI-DCM(iNI-DCM) patients. The main outcome was a composite of death/heart transplantation/life-threatening arrhythmias. Results: Overall 114 patients (52 with ACM and 62 with iNI-DCM) were included. ACM patients were more often males compared to iNI-DCM (90% vs 64%, respectively, p ≤ 0.001) and were characterized by a more pronounced biventricular adverse remodelling than iNI-DCM, i.e. lower LVEF (31 ± 12% vs 38 ± 11% respectively, p = 0.001) and larger left ventricular end-diastolic volume (116 ± 40 ml/m2 vs 67 ± 20 ml/m2 respectively, p < 0.001). Similarly to iNI-DCM, late gadolinium enhancement (LGE), mainly midwall, was present in more than 40% of ACM patients but, conversely, it was not associated with adverse outcome(p = 0.15). LGE localization was prevalently septal (87%) in ACM vs lateral in iNI-DCM(p < 0.05). Over a median follow-up of 42 months [Interquartile Range 24–68], adverse outcomes were similar in both groups(p = 0.67). Conclusions: ACM represents a specific phenotype of NI-DCM, with severe morpho-functional features at the onset, but similar long-term outcomes compared to iNI-DCM. Despite the presence and pattern of distribution of LGE was comparable, ACM and iNI-DCM showed a different LGE localization, mostly septal in ACM and lateral in iNI-DCM, with different prognostic impact.
- Published
- 2021
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.