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Your search keyword '"Khesin IaE"' showing total 4 results
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4 results on '"Khesin IaE"'

1. [Differences in the antiviral and antioncogenic action of interferons produced in murine peritoneal cells and in Krebs-2 ascitic carcinoma cells].

Author

Marchenko VI, Pokidysheva LN, Malinovskaia VV, Aliab'eva TI, and Khesin IaE

Subjects
Acid Phosphatase metabolism, Animals, Carcinoma, Krebs 2 drug therapy, Histocytochemistry, Interferons antagonists & inhibitors, Interferons therapeutic use, L Cells enzymology, Mice, Vesicular stomatitis Indiana virus drug effects, Antineoplastic Agents therapeutic use, Ascitic Fluid cytology, Carcinoma, Krebs 2 analysis, Interferons isolation & purification, Macrophages analysis
Abstract

Comparisons of native preparation of mouse interferons, "macrophage" and "Krebs" revealed some differences, Thus, the minimal time necessary for the development of resistance to vesicular stomatitis virus (VSV) in L cells treated with "macrophage" and "Krebs" interferon was 5 and 2 hours, respectively. The activity of the lysosomal enzyme of acid phosphatase was considerably higher in the cells treated with "Krebs" interferon and infected with VSV than with "macrophage" interferon. Differences in the antiviral and antioncogenic properties of fractions No. 1 and No. 5 of these interferons obtained in fractionation of native interferon preparations by the cryomethod were demonstrated. In particular, fraction No. 5 of "Krebs" interferon, in contrast to that of "macrophage" interferon, had no antioncogenic properties but did have antiviral properties. It is suggested that these differences are due to the presence in native preparations of different substances capable of exerting an effect on interferon.

Published
1977

2. [The influence of the immunologic reactivity of rabbit leukocytes and macrophages on interferon production under the influence of herpesvirus].

Author

Bocharov AF, Moĭsiadi SA, Amchenkova AM, Voronina FV, and Khesin IaE

Subjects
Acid Phosphatase metabolism, Animals, Culture Techniques, Dihydrolipoamide Dehydrogenase metabolism, Glucosephosphate Dehydrogenase metabolism, Herpesviridae Infections enzymology, Herpesviridae Infections metabolism, Histocytochemistry, Leukocytes enzymology, Leukocytes metabolism, Macrophages metabolism, NAD, RNA metabolism, Rabbits, Virus Cultivation, Herpesviridae immunology, Herpesviridae Infections immunology, Interferons biosynthesis, Leukocytes immunology, Macrophages immunology
Published
1971

3. [A cytologic study of mouse abdominal cavity exudate during in vitro interferon production].

Author

Khesin IaE, Voronina FV, and Amchenkova AM

Subjects
Acid Phosphatase metabolism, Animals, Glucosephosphate Dehydrogenase metabolism, Macrophages enzymology, Mice, Newcastle Disease enzymology, Oxidoreductases metabolism, RNA biosynthesis, Ascitic Fluid metabolism, Interferons biosynthesis, Leukocytes metabolism, Macrophages metabolism, Newcastle Disease metabolism
Published
1970

4. [Morphological, cytochemical and biochemical changes in peritoneal macrophages (normal, activated and tolerant) in the process of interferon formation].

Author

Khesin IaE, Voronina FV, Marchenko VI, Rusanova NA, and Balandin IG

Subjects
Acid Phosphatase metabolism, Animals, Dihydrolipoamide Dehydrogenase metabolism, Interferons pharmacology, Mice, Newcastle disease virus, RNA biosynthesis, Ascitic Fluid cytology, Interferons biosynthesis, Macrophages drug effects, Macrophages enzymology
Published
1973

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