Search

An increasing number of machine learning applications are being developed and applied to digital pathology, including hematopathology. The goal of these modern computerized tools is often to support diagnostic workflows by extracting and summarizing information from multiple data sources, including digital images of human tissue. Hematopathology is inherently multimodal and can serve as an ideal case study for machine learning applications. However, hematopathology also poses unique challenges compared to other pathology subspecialities when applying machine learning approaches. By modeling the pathologist workflow and thinking process, machine learning algorithms may be designed to address practical and tangible problems in hematopathology. In this article, we discuss the current trends in machine learning in hematopathology. We review currently available machine learning enabled medical devices supporting hematopathology workflows. We then explore current machine learning research trends of the field with a focus on bone marrow cytology and histopathology, and how adoption of new machine learning tools may be enabled through the transition to digital pathology., (© 2023 The Authors. International Journal of Laboratory Hematology published by John Wiley & Sons Ltd.)

Within artificial intelligence and machine learning, a generative model is a powerful tool for learning any kind of data distribution. With the advent of deep learning and its success in image recognition, the field of deep generative models has clearly emerged as one of the promising fields for medical imaging. In a recent issue of The Journal of Pathology, Levine, Peng et al demonstrate the ability of generative models to synthesize high‐quality pathology images. They suggested that generative models can serve as an unlimited source of images either for educating freshman pathologists or training machine learning models for diverse image analysis tasks, especially in scarce cases, while resolving patients' privacy and confidentiality concerns. © 2020 The Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Abstract: Finding an optimal threshold in order to segment digital images is a difficult task in image processing. Numerous approaches to image thresholding already exist in the literature. In this work, a reinforced threshold fusion for image binarization is introduced which aggregates existing thresholding techniques. The reinforcement agent learns the optimal weights for different thresholds and segments the image globally. A fuzzy reward function is employed to measure object similarities between the binarized image and the original gray-level image, and provide feedback to the agent. The experiments show that promising improvement can be obtained. Three well-established thresholding techniques are combined by the reinforcement agent and the results are compared using error measurements based on ground-truth images. [Copyright &y& Elsevier]

Traditional image enhancement algorithms do not account for the subjective evaluation of human operators. Every observer has a different opinion of an ideally enhanced image. Automated Techniques for obtaining a subjectively ideal image enhancement are desirable, but currently do not exist. In this paper, we demonstrate that Reinforcement Learning is a potential method for solving this problem. We have developed an agent that uses the Q-learning algorithm. The agent modifies the contrast of an image with a simple linear point transformation based on the histogram of the image and feedback it receives from human observers. The results of several testing sessions have indicated that the agent performs well within a limited number of iterations. [ABSTRACT FROM AUTHOR]