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This study investigated the application of high-resolution satellite imagery from SuperDove satellites combined with machine learning algorithms to estimate the spatiotemporal variability of some winter wheat parameters, including the relative leaf chlorophyll content (RCC), relative water content (RWC), and aboveground dry matter (DM). The research was carried out within an experimental field in Southern Italy during the 2024 growing season. Different machine learning (ML) algorithms were trained and compared using spectral band data and calculated vegetation indices (VIs) as predictors. Model performance was assessed using R2 and RMSE. The ML models tested were random forest (RF), support vector regressor (SVR), and extreme gradient boosting (XGB). RF outperformed the other ML algorithms in the prediction of RCC when using VIs as predictors (R2 = 0.81) and in the prediction of the RWC and DM when using spectral bands data as predictors (R2 = 0.71 and 0.87, respectively). Model explainability was assessed with the SHAP method. A SHAP analysis highlighted that GNDVI, Cl1, and NDRE were the most important VIs for predicting RCC, while yellow and red bands were the most important for DM prediction, and yellow and nir bands for RWC prediction. The best model found for each target was used to model its seasonal trend and produce a variability map. This approach highlights the potential of integrating ML and high-resolution satellite imagery for the remote monitoring of wheat, which can support sustainable farming practices. [ABSTRACT FROM AUTHOR]