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Change detection determines and evaluates changes by comparing bi-temporal images, which is a challenging task in the remote-sensing field. To better exploit the high-level features, deep-learning-based change-detection methods have attracted researchers' attention. Most deep-learning-based methods only explore the spatial–spectral features simultaneously. However, we assume the key spatial-change areas should be more important, and attention should be paid to the specific bands which can best reflect the changes. To achieve this goal, we propose the spatial–spectral joint attention network (SJAN). Compared with traditional methods, SJAN introduces the spatial–spectral attention mechanism to better explore the key changed areas and the key separable bands. To be more specific, a novel spatial-attention module is designed to extract the spatially key regions first. Secondly, the spectral-attention module is developed to adaptively focus on the separable bands of land-cover materials. Finally, a novel objective function is proposed to help the model to measure the similarity of learned spatial–spectral features from both spectrum amplitude and angle perspectives. The proposed SJAN is validated on three benchmark datasets. Comprehensive experiments have been conducted to demonstrate the effectiveness of the proposed SJAN. [ABSTRACT FROM AUTHOR]

• Machine learning methods were used to assess dosimetric associations with patient-reported outcomes. • Full range of dosimetric quantities demonstrated predictive ability for patient-reported toxicities after prostate SBRT. • Dosimetric predictors with patient-reported toxicities were identified using advanced ML methods. • Predictive DVH metrics can be employed to refine planning guidelines to further reduce toxicity. • Outcome-driven treatment planning may further improve treatment outcome. This study aims to evaluate the associations between dosimetric parameters and patient-reported outcomes, and to identify latent dosimetric parameters that most correlate with acute and subacute patient-reported urinary and rectal toxicity after prostate stereotactic body radiotherapy (SBRT) using machine learning methods. Eighty-six patients who underwent prostate SBRT (40 Gy in 5 fractions) were included. Patient-reported health-related quality of life (HRQOL) outcomes were derived from bowel and bladder symptom scores on the Expanded Prostate Cancer Index Composite (EPIC-26) at 3 and 12 months post-SBRT. We utilized ensemble machine learning (ML) to interrogate the entire dose–volume histogram (DVH) to evaluate relationships between dose–volume parameters and HRQOL changes. The latent predictive dosimetric parameters that were most associated with HRQOL changes in urinary and rectal function were thus identified. An external cohort of 26 prostate SBRT patients was acquired to further test the predictive models. Bladder dose–volume metrics strongly predicted patient-reported urinary irritative and incontinence symptoms (area under the curves [AUCs] of 0.79 and 0.87, respectively) at 12 months. Maximum bladder dose, bladder V102.5%, bladder volume, and conformity indices (V50/VPTV and V100/VPTV) were most predictive of HRQOL changes in both urinary domains. No strong rectal toxicity dosimetric association was identified (AUC = 0.64). We demonstrated the application of advanced ML methods to identify a set of dosimetric variables that most highly correlated with patient-reported urinary HRQOL. DVH quantities identified with these methods may be used to achieve outcome-driven planning objectives to further reduce patient-reported toxicity with prostate SBRT. [ABSTRACT FROM AUTHOR]

Abstract: By inspiration of the granular evolutionary algorithm, a Granular Agent Evolutionary Classification (GAEC) algorithm for the classification task in data mining is proposed. The method uses the granular agent to denote the set of some examples that have similar attributions and the knowledge base guides the evolution of granular agent. Also some granular evolutionary operators are designed for classification problem. Assimilation operator, exchange operator, and differentiation operator reflect the competitive, cooperative and self-learning ability of agent, respectively. Finally, some classification rules are extracted from granular agents by some strategy to forecast the sort of new data. Empirical study contains UCI data sets, KDDCUP99 data sets and remote image recognition. The test results show that the algorithm has a good classification prediction, and only need a small price for the training time. In most UCI data sets, the performance of GAEC is better than G-NET, OCEC and C4.5, which have good performance. At the same time, some Gaussian White Noise attributes are added to these UCI data sets and the results show GACE has some anti-noise abilities. To test the scalability of GAEC, two functions along two dimensions, the number of training examples and the number of attributes are used. Also, GAEC are applied to some real world fields, intrusion detection system and remote sensing image recognition. The experiments for KDDCUP99 verify GAEC has capability to deal with massive data in real world and good predicting capability for unknown type data. At last, the accuracy rate of GAEC is also good for the remote sensing image recognition. [Copyright &y& Elsevier]