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The modern development of healthcare is characterized by a set of large volumes of tabular data for monitoring and diagnosing the patient's condition. In addition, modern methods of data engineering allow the synthesizing of a large number of features from an image or signals, which are presented in tabular form. The possibility of high-precision and high-speed processing of such large volumes of medical data requires the use of artificial intelligence tools. A linear machine learning model cannot accurately analyze such data, and traditional bagging, boosting, or stacking ensembles typically require significant computing power and time to implement. In this paper, the authors proposed a method for the analysis of large sets of medical data, based on a designed linear ensemble method with a non-iterative learning algorithm. The basic node of the new ensemble is an extended-input SGTM neural-like structure, which provides high-speed data processing at each level of the ensemble. Increasing prediction accuracy is ensured by dividing the large dataset into parts, the analysis of which is carried out in each node of the ensemble structure and taking into account the output signal from the previous level of the ensemble as an additional attribute on the next one. Such a design of a new ensemble structure provides both a significant increase in the prediction accuracy for large sets of medical data analysis and a significant reduction in the duration of the training procedure. Experimental studies on a large medical dataset, as well as a comparison with existing machine learning methods, confirmed the high efficiency of using the developed ensemble structure when solving the prediction task., (© 2024. The Author(s).)

Modern medical diagnosis, treatment, or rehabilitation problems of the patient reach completely different levels due to the rapid development of artificial intelligence tools. Methods of machine learning and optimization based on the intersection of historical data of various volumes provide significant support to physicians in the form of accurate and fast solutions of automated diagnostic systems. It significantly improves the quality of medical services. This special issue deals with the problems of medical diagnosis and prognosis in the case of short datasets. The problem is not new, but existing machine learning methods do not always demonstrate the adequacy of prediction or classification models, especially in the case of limited data to implement the training procedures. That is why the improvement of existing and development of new artificial intelligence tools that will be able to solve it effectively is an urgent task. The special issue contains the latest achievements in medical diagnostics based on the processing of small numerical and image-based datasets. Described methods have a strong theoretical basis, and numerous experimental studies confirm the high efficiency of their application in various applied fields of Medicine.

Amidst rapid technological and healthcare advancements, biomedical data classification using machine learning (ML) is pivotal for revolutionizing medical diagnosis, treatment, and research by organizing vast healthcarerelated data. Despite efforts to apply single ML models on clean datasets, satisfactory classification accuracy can still be elusive. In such cases, MLbased ensembles offer a promising solution. This paper explores cascaded ensembles as highly accurate methods. Existing cascade classifiers often partition large datasets into equal unique parts, limiting accuracy due to insufficient amount of useful information processed by weak classifiers of all levels of the cascade ensemble. To address this, we propose an improved cascaded ensemble scheme using a different data sampling approach. Our method forms larger subsamples at each cascade level, enhancing accuracy, and generalization properties during biomedical data analysis. Experimental comparisons demonstrate substantial increases in classification accuracy and generalization properties of the improved cascade ensemble. [ABSTRACT FROM AUTHOR]

We live in the era of large data analysis, where processing vast datasets has become essential for uncovering valuable insights across various domains of our lives. Machine learning (ML) algorithms offer powerful tools for processing and analyzing this abundance of information. However, the considerable time and computational resources needed for training ML models pose significant challenges, especially within cascade schemes, due to the iterative nature of training algorithms, the complexity of feature extraction and transformation processes, and the large sizes of the datasets involved. This paper proposes a modification to the existing ML-based cascade scheme for analyzing large biomedical datasets by incorporating principal component analysis (PCA) at each level of the cascade. We selected the number of principal components to replace the initial inputs so that it ensured 95% variance retention. Furthermore, we enhanced the training and application algorithms and demonstrated the effectiveness of the modified cascade scheme through comparative analysis, which showcased a significant reduction in training time while improving the generalization properties of the method and the accuracy of the large data analysis. The improved enhanced generalization properties of the scheme stemmed from the reduction in nonsignificant independent attributes in the dataset, which further enhanced its performance in intelligent large data analysis. [ABSTRACT FROM AUTHOR]

Today, the field of biomedical engineering spans numerous areas of scientific research that grapple with the challenges of intelligent analysis of small datasets. Analyzing such datasets with existing artificial intelligence tools is a complex task, often complicated by issues like overfitting and other challenges inherent to machine learning methods and artificial neural networks. These challenges impose significant constraints on the practical application of these tools to the problem at hand. While data augmentation can offer some mitigation, existing methods often introduce their own set of limitations, reducing their overall effectiveness in solving the problem. In this paper, the authors present an improved neural network-based technology for predicting outcomes when analyzing small and extremely small datasets. This approach builds on the input doubling method, leveraging response surface linearization principles to improve performance. Detailed flowcharts of the improved technology's operations are provided, alongside descriptions of new preparation and application algorithms for the proposed solution. The modeling, conducted using two biomedical datasets with optimal parameters selected via differential evolution, demonstrated high prediction accuracy. A comparison with several existing methods revealed a significant reduction in various errors, underscoring the advantages of the improved neural network technology, which does not require training, for the analysis of extremely small biomedical datasets. [ABSTRACT FROM AUTHOR]

This paper provides a method for predicting the energy efficiency of buildings using artificial intelligence tools. The scopes is twofold: prediction of the levels of the heating load and cooling load of buildings. A feature of this research is the performance of intellectual analysis in conditions of a limited amount of data when solving the stated tasks. An improved method of augmentation and prediction (input-doubling method) is proposed by processing data within each cluster of the studied dataset. The selection of the latter occurs due to the use of the fast and easy-to-implement k-means method. Next, a prediction is made using the input-doubling method within each separate cluster. The simulation of the method was performed on a real-world dataset of 768 observations. The proposed approach was found to have a high prediction accuracy in the absence of overfitting and high generalization properties of the improved method. Comparison with existing methods showed an increase in accuracy by 40-46% (MSE) compared to SVR with rbf kernel, which is the basis for the improved method, and by 5-12% (MSE) compared to the closest existing hierarchical predictor. [ABSTRACT FROM AUTHOR]

It is a serious global health concern that chronic kidney disease (CKD) kills millions of people each year as a result of poor lifestyle choices and inherited factors. Effective prediction tools for prior detection are essential due to the growing number of patients with this disease. By utilizing machine learning (ML) approaches, this study aids specialists in studying precautionary measures for CKD through prior detection. The main objective of this paper is to predict and classify chronic kidney disease using ML approaches on a publicly available dataset. The dataset of CKD has been taken from the publicly available and accessible dataset Irvine ML Repository, which included 400 instances. ML methods (Support Vector Machine (SVM), K-Nearest Neighbors (KNN), random forest (RF), Logistic Regression (LR), and Decision Tree (DT) Classifier) are used as base learners and their performance has been compared with eXtreme Gradient Boosting (XGBoost). All ML algorithms are evaluated against different performance parameters: accuracy, recall, precision, and F1-measure. The results indicated that XGBoost outperformed with 98.00% accuracy as compared to other ML algorithms. For policymakers to forecast patterns of CKD in the population, the model put forth in this paper may be helpful. The model may enable careful monitoring of individuals who are at risk, early CKD detection, better resource allocation, and management that is patient-centered. [ABSTRACT FROM AUTHOR]

This paper presents a parallel approach to the Levenberg-Marquardt algorithm (LM). The use of the Levenberg-Marquardt algorithm to train neural networks is associated with significant computational complexity, and thus computation time. As a result, when the neural network has a big number of weights, the algorithm becomes practically ineffective. This article presents a new parallel approach to the computations in Levenberg-Marquardt neural network learning algorithm. The proposed solution is based on vector instructions to effectively reduce the high computational time of this algorithm. The new approach was tested on several examples involving the problems of classification and function approximation, and next it was compared with a classical computational method. The article presents in detail the idea of parallel neural network computations and shows the obtained acceleration for different problems. [ABSTRACT FROM AUTHOR]

Today's world faces a serious public health problem with cancer. One type of cancer that begins in the breast and spreads to other body areas is breast cancer (BC). Breast cancer is one of the most prevalent cancers that claim the lives of women. It is also becoming clearer that most cases of breast cancer are already advanced when they are brought to the doctor's attention by the patient. The patient may have the evident lesion removed, but the seeds have reached an advanced stage of development or the body's ability to resist them has weakened considerably, rendering them ineffective. Although it is still much more common in more developed nations, it is also quickly spreading to less developed countries. The motivation behind this study is to use an ensemble method for the prediction of BC, as an ensemble model aims to automatically manage the strengths and weaknesses of each of its separate models, resulting in the best decision being made overall. The main objective of this paper is to predict and classify breast cancer using Adaboost ensemble techniques. The weighted entropy is computed for the target column. Taking each attribute's weights results in the weighted entropy. Each class's likelihood is represented by the weights. The amount of information gained increases with a decrease in entropy. Both individual and homogeneous ensemble classifiers, created by mixing Adaboost with different single classifiers, have been used in this work. In order to deal with the class imbalance issue as well as noise, the synthetic minority over-sampling technique (SMOTE) was used as part of the data mining pre-processing. The suggested approach uses a decision tree (DT) and naive Bayes (NB), with Adaboost ensemble techniques. The experimental findings shown 97.95% accuracy for prediction using the Adaboost-random forest classifier. [ABSTRACT FROM AUTHOR]

The modern development of the biomedical engineering area is accompanied by the availability of large volumes of data with a non-linear response surface. The effective analysis of such data requires the development of new, more productive machine learning methods. This paper proposes a cascade ensemble that combines the advantages of using a high-order Wiener polynomial and Stochastic Gradient Descent algorithm while eliminating their disadvantages to ensure a high accuracy of the approximation of such data with a satisfactory training time. The work presents flow charts of the learning algorithms and the application of the developed ensemble scheme, and all the steps are described in detail. The simulation was carried out based on a real-world dataset. Procedures for the proposed model tuning have been performed. The high accuracy of the approximation based on the developed ensemble scheme was established experimentally. The possibility of an implicit approximation by high orders of the Wiener polynomial with a slight increase in the number of its members is shown. It ensures a low training time for the proposed method during the analysis of large datasets, which provides the possibility of its practical use in the biomedical engineering area. [ABSTRACT FROM AUTHOR]

Data normalization is a data preprocessing task and one of the first to be performed during intellectual analysis, particularly in the case of tabular data. The importance of its implementation is determined by the need to reduce the sensitivity of the artificial intelligence model to the values of the features in the dataset to increase the studied model's adequacy. This paper focuses on the problem of effectively preprocessing data to improve the accuracy of intellectual analysis in the case of performing medical diagnostic tasks. We developed a new two-step method for data normalization of numerical medical datasets. It is based on the possibility of considering both the interdependencies between the features of each observation from the dataset and their absolute values to improve the accuracy when performing medical data mining tasks. We describe and substantiate each step of the algorithmic implementation of the method. We also visualize the results of the proposed method. The proposed method was modeled using six different machine learning methods based on decision trees when performing binary and multiclass classification tasks. We used six real-world, freely available medical datasets with different numbers of vectors, attributes, and classes to conduct experiments. A comparison between the effectiveness of the developed method and that of five existing data normalization methods was carried out. It was experimentally established that the developed method increases the accuracy of the Decision Tree and Extra Trees Classifier by 1–5% in the case of performing the binary classification task and the accuracy of the Bagging, Decision Tree, and Extra Trees Classifier by 1–6% in the case of performing the multiclass classification task. Increasing the accuracy of these classifiers only by using the new data normalization method satisfies all the prerequisites for its application in practice when performing various medical data mining tasks. [ABSTRACT FROM AUTHOR]

The production of biocompatible medical implants is accompanied by technological and time costs. As a result, to be used in the human body, such a product must be of the highest quality. Assessing the quality of biomedical implants made of titanium alloys is relevant given their impact on the health and life of their wearer. In the case of the production of such implants by additive technologies, an important task is to evaluate the properties of the alloys from which it is made. The modern development of Artificial Intelligence allows replacing traditional assessment methods with machine learning methods for such assessment. Existing machine learning methods demonstrate very low classification accuracy, and existing hybrid systems, although increasing classification accuracy, are not sufficient to apply such schemes in practice. The authors improved the hybrid PNN-SVM system to solve this problem in this paper. It is based on the combining use of PNN, Ito Decomposition, and SVM. The PNN's summation layer outputs were used as additional attributes to an initial dataset. Ito decomposition was used to nonlinearly model relationships between features of an extended dataset. Further classification is carried out using SVM with a linear kernel. The proposed approach's modeling is performed based on a real-world dataset using the smart web service designed by the authors. Experimentally found an increase in the classification accuracy by 6% of the proposed system compared to existing ones. It makes it possible to use it in practice. Designed smart web service, in which the authors implemented both improved and existing hybrid classification schemes allows to quickly, easily, and without high qualification of the user to implement and explore in more detail chosen classification scheme when classification tasks in various fields of industry. [ABSTRACT FROM AUTHOR]

The modern technology universities have the necessary resource and material base for developing and transferring R&D products. However, the cost estimation process is not formalized. There are many methods of estimating the cost of R&D products' commercialization processes. However, in some cases, we cannot consider any single technique to be the best one as each of them has advantages and disadvantages. In such conditions, all efforts should be made to use a combination of the estimation techniques to arrive at a better cost and quality estimate. The effectiveness of the valuation of R&D products is of particular importance in today's economy and due to the need to analyze large data sets prepared for transfer from universities to the business environment. This paper presents the model, two methods, and general information technology for R&D products' readiness level assessment and R&D products' cost estimation. The article presents the complex method for determining the cost of R&D products, which will allow: increasing the efficiency of the transfer, commercialization, and market launch of R&D products, and promoting the interaction of all components of the national innovation infrastructure, innovations, etc. The need to consider many different indicators when evaluating R&D products has determined the need to use machine learning algorithms. We have designed a new machine learning-based model for the readiness assessment of R&D products, which is based on the principle of "crowd wisdom" and uses a stacking strategy to integrate machine learning methods. It is experimentally established that the new stacking model based on machine learning algorithms that use random forest as a meta-algorithm provides a minimum of a 1.03 times higher RMSE compared to other ensemble strategies. [ABSTRACT FROM AUTHOR]

In recent years, machine-learning-based approaches have become of considerable interest to the efficient processing of short or limited data samples. Its so-called small data approach. This is due to the significant growth of new intellectual analysis tasks in various industries, which are characterized by limited historical data. These include Materials Science, Economics, Medicine, and so on. An effective processing of short datasets is especially acute in medicine. Insufficient number of vectors, significant gaps in the data collected during the supervision of patient's treatment or rehabilitation, reduces the effectiveness or prevents effective intellectual analysis based on them. This paper presents a new approach to processing short medical data samples. The basis of the developed method is SVR with RBF kernel. The algorithmic implementation of the method in both operation modes is described. Experimental modeling on a real short data set (Trabecular bone data) is conducted. It contained only 35 observations. A comparison of the method with a number of existing machine learning methods is conducted. It is experimental established the highest accuracy of the method among those considered. The developed method has potential opportunities for wide application in various fields of medicine. [ABSTRACT FROM AUTHOR]

The problem of effective intellectual analysis in the case of handling short datasets is topical in various application areas. Such problems arise in medicine, economics, materials science, science, etc. This paper deals with a new additive input-doubling method designed by the authors for processing short and very short datasets. The main steps of the method should include the procedure of data augmentation within the existing dataset both in rows and columns (without training), the use of nonlinear SVR to implement the training procedure, and the formation of the result based on the author's procedure. The authors show that the developed data augmentation procedure corresponds to the principles of axial symmetry. The training and application procedures of the method developed are described in detail, and two algorithmic implementations are presented. The optimal parameters of the method operation were selected experimentally. The efficiency of its work during the processing of short datasets for solving the prediction task was established experimentally by comparison with other methods of this class. The highest prediction accuracy based on both proposed algorithmic implementations of a method among all of the investigated ones was defined. The main areas of application of the developed method are described, and its shortcomings and prospects of further research are given. [ABSTRACT FROM AUTHOR]