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Your search keyword '"rab GTP-Binding Proteins metabolism"' showing total 211 results

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211 results on '"rab GTP-Binding Proteins metabolism"'

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1. Prolonged glutamine starvation reactivates mTOR to inhibit autophagy and initiate autophagic lysosome reformation to maintain cell viability.

2. Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis.

3. ELD607 specifically traffics Orai1 to the lysosome leading to inhibition of store operated calcium entry.

4. Angiogenesis is limited by LIC1-mediated lysosomal trafficking.

5. LRRK2 and RAB8A regulate cell death after lysosomal damage in macrophages through cholesterol-related pathways.

6. LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis.

7. A new player in the biogenesis of lysosome-related organelles.

8. Downregulation of O-GlcNAc transferase activity impairs basal autophagy and late endosome positioning under nutrient-rich conditions in human colon cells.

9. CALCOCO2/NDP52 associates with RAB9 to initiate an antiviral response to hepatitis B virus infection through a lysosomal degradation pathway.

10. Lysosomal TBK1 responds to amino acid availability to relieve Rab7-dependent mTORC1 inhibition.

11. Endolysosomal channel TMEM175 mediates antitoxin activity of DABMA.

12. TMEM9 activates Rab9-dependent alternative autophagy through interaction with Beclin1.

13. Cholesterol-rich lysosomes induced by respiratory syncytial virus promote viral replication by blocking autophagy flux.

14. Biogenic selenium nanoparticles alleviate intestinal barrier injury in mice through TBC1D15/Fis1/Rab7 pathway.

15. RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts.

16. Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.

17. Initiation of acute pancreatitis in mice is independent of fusion between lysosomes and zymogen granules.

18. CX-4945 (Silmitasertib) Induces Cell Death by Impairing Lysosomal Utilization in KRAS Mutant Cholangiocarcinoma Cell Lines.

19. Reconstitution of Rab11-FIP4 Expression Rescues Cellular Homeostasis in Cystinosis.

20. Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes.

21. Phosphorylation of Rab29 at Ser185 regulates its localization and role in the lysosomal stress response in concert with LRRK2.

22. The Role of LRRK2 in Intracellular Organelle Dynamics.

23. Pathogenic LRRK2 compromises the subcellular distribution of lysosomes in a Rab12-RILPL1-dependent manner.

24. RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

25. Lysosomal positioning regulates Rab10 phosphorylation at LRRK2 + lysosomes.

26. Endocytosed HIV-1 Envelope Glycoprotein Traffics to Rab14 + Late Endosomes and Lysosomes to Regulate Surface Levels in T-Cell Lines.

27. Rab21 Protein Is Degraded by Both the Ubiquitin-Proteasome Pathway and the Autophagy-Lysosome Pathway.

28. Drosophila Rab39 Attenuates Lysosomal Degradation.

29. An ancient RAB5 governs the formation of additional vacuoles and cell shape in petunia petals.

30. ORP1L mediated PI(4)P signaling at ER-lysosome-mitochondrion three-way contact contributes to mitochondrial division.

31. Who's in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond.

32. The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion.

33. Knockout analysis of Rab6 effector proteins revealed the role of VPS52 in the secretory pathway.

34. Shigella escapes lysosomal degradation through inactivation of Rab31 by IpaH4.5.

35. CLN5 and CLN3 function as a complex to regulate endolysosome function.

36. Functional complementation of V-ATPase a subunit isoforms in osteoclasts.

37. Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.

38. Rab44 isoforms similarly promote lysosomal exocytosis, but exhibit differential localization in mast cells.

39. Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson's disease.

40. Preclinical modeling of chronic inhibition of the Parkinson's disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo.

41. Better Together: Current Insights Into Phagosome-Lysosome Fusion.

42. Rab GTPases in the differential processing of phagocytosed pathogens versus efferocytosed apoptotic cells.

43. The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.

44. A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

45. Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation.

46. Nicotine Modulates CTSS (Cathepsin S) Synthesis and Secretion Through Regulating the Autophagy-Lysosomal Machinery in Atherosclerosis.

47. Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis.

48. Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations.

49. GSK-3-TSC axis governs lysosomal acidification through autophagy and endocytic pathways.

50. RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism.

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