1. Lymphocyte surface marker studies in the diagnosis of unexplained lymphocytosis.
- Author
-
Quantz MC, Robinson JB, Sachs V, and Pinkerton PH
- Subjects
- Adult, Aged, Aged, 80 and over, Antigens, Surface analysis, B-Lymphocytes immunology, Cell Count, Female, Humans, Lymphocytosis immunology, Lymphoproliferative Disorders diagnosis, Male, Middle Aged, T-Lymphocytes immunology, Lymphocytes immunology, Lymphocytosis diagnosis
- Abstract
Fifty-six patients with unexplained lymphocytosis were investigated with a panel of antibodies to lymphocyte surface antigens. In 23 the distribution of cell surface markers suggested reactive lymphocytosis. The remaining 33 patients showed a distribution of cell surface markers that indicated or suggested a diagnosis of B-cell lymphoproliferative disease. Two illustrative case reports show how such studies performed early in the investigation of unexplained lymphocytosis may permit earlier diagnosis of the underlying mechanism.
- Published
- 1987