1. Clinical course and outcome after esophagectomy with three-field lymphadenectomy in esophageal cancer.
- Author
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Natsugoe, Shoji, Matsumoto, Masataka, Okumura, Hiroshi, Uchikado, Yasuto, Setoyama, Tetsuro, Sasaki, Ken, Sakurai, Toshihide, Omoto, Itaru, Owaki, Tetsuhiro, Shinchi, Hiroyuki, Ueno, Shinichi, and Ishigami, Sumiya
- Subjects
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ESOPHAGEAL cancer , *ESOPHAGECTOMY , *ADJUVANT treatment of cancer , *LYMPH nodes , *CANCER patients - Abstract
Esophagectomy with three-field lymphadenectomy has been performed for esophageal cancer. Detailed analysis of cause of death and mode of recurrence is required to determine the need for further adjuvant therapy and follow-up. A total of 208 patients who underwent esophagectomy through right thoracotomy with three-field lymphadenectomy were enrolled into the present study. Mode of first recurrence was divided into four groups: lymph node, hematogenous, mixed, and local recurrence. Excluding 16 hospital deaths, the number of deaths and 5-year survival rates were 104 patients and 7.8% for cancer recurrence, 12 patients and 53.8% for second primary cancers in other organs, and 34 patients and 31.0% for causes of death unrelated to carcinoma. In the 104 patients with relapse, 5-year survival rate of patients was 14.3% with lymph node recurrence ( n = 29), 9.1% with hematogenous recurrence ( n = 32), 3.1% with mixed recurrence ( n = 35), and 12.5% with local recurrence ( n = 8). To improve outcomes for esophagectomy with three-field lymphadenectomy, early detection of recurrent disease and regular examination of the entire body for secondary cancer is necessary. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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