1. Changes in the lipid composition of blood plasma and liver in rats induced by severe psychic trauma.
- Author
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Tsikunov SG, Klyueva NN, Kusov AG, Vinogradova TV, Klimenko VM, and Denisenko AD
- Subjects
- Animals, Male, Rats, Stress Disorders, Post-Traumatic psychology, Behavior, Animal physiology, Disease Models, Animal, Lipoproteins, HDL blood, Liver metabolism, Movement physiology, Stress Disorders, Post-Traumatic blood, Stress Disorders, Post-Traumatic metabolism, Triglycerides blood
- Abstract
The concentration of high-density lipoprotein cholesterol and triglycerides in rat serum sharply decreased after psychic trauma caused by life hazard. The content of these substances remained unchanged for not less than 1 week after trauma. The concentration of high-density lipoprotein cholesterol was low, while serum content of triglycerides increased 6 weeks after trauma. The concentration of high-density lipoprotein cholesterol significantly decreased after repeated psychic trauma. These changes were accompanied by a sharp increase in the concentration of triglycerides in the serum. Total cholesterol concentration in the liver decreased under these conditions.
- Published
- 2006
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