1. Pay Attention to Biological Nanoparticles when Studying the Protein Corona on Nanomedicines.
- Author
-
Simonsen JB and Münter R
- Subjects
- Lipoproteins chemistry, Nanomedicine methods, Nanoparticles chemistry, Particle Size, Protein Corona chemistry, Extracellular Vesicles chemistry, Lipoproteins analysis, Nanoparticles analysis, Protein Corona analysis
- Abstract
The protein corona of nanoparticles has in recent years received considerable attention, and even been postulated to be the missing link in the translation of nanomedicines from benchtop to bedside. We highlight the different types of biological nanoparticles present in blood that need to be considered in the protein corona research field. We map their size, density, and plasma concentrations, and use this information to stress potential challenges related to the isolation of nanomedicines-with a particular focus on liposomes-when using the traditional isolation methods that separate according to size and density., (© 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)
- Published
- 2020
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