Search

Abstract: Three new limonoids, ceramicines B–D (1–3), have been isolated from the bark of Chisocheton ceramicus. Structures and stereochemistry of 1–3 were fully elucidated and characterized by 2D NMR analysis. Ceramicines exhibited a moderate antiplasmodial activity. [Copyright &y& Elsevier]

Abstract: Two novel limonoids, ceramicine A (1) without any methyls at C-4, and walsogyne A (2) with a ring C-seco limonoid, have been isolated from the barks of Chisocheton ceramicus and Walsura chrysogyne, respectively, and the structures were fully elucidated on the basis of spectroscopic data. Ceramicine A (1) and walsogyne A (2) showed a moderate cytotoxic activity. [Copyright &y& Elsevier]

Abstract: Six new limonoids, Walsogynes B (1)–G (6), were isolated from the barks of Walsura chrysogyne, and their structures were determined on the basis of NMR and MS spectroscopic analyses in combination with NMR chemical shifts calculations. Walsogynes (1)–E (4) were concluded to be 11,12-seco limonoids sharing a unique dodecahydronaphtho[1,8-bc:5,4-b′c′]difuran skeleton, and walsogynes F (5) and G (6) to be 11,12-seco limonoids with a dodecahydro-1H-naphtho[1,8-bc:3,4-c′]difuran skeleton. Their absolute configurations were assigned through comparison of the calculated and experimental CD spectra. Walsogynes showed a moderate in vitro cytotoxic activity against various cancer cell lines. [Copyright &y& Elsevier]

Abstract: Five new cytotoxic limonoids, erythrocarpines A–E (1–5), were isolated from the bark of Chisocheton erythrocarpus Hiern. Chemical structures, stereochemistry, and conformation were fully elucidated and characterized by 2D NMR, MS, and computational methods. [Copyright &y& Elsevier]