10 results
Search Results
2. The paper grip test for screening on intrinsic muscle paralysis in the foot of leprosy patients.
- Author
-
de Win MM, Theuvenet WJ, Roche PW, de Bie RA, and van Mameren H
- Subjects
- Adult, Aged, Female, Foot Deformities, Acquired prevention & control, Humans, Male, Mass Screening, Middle Aged, Muscle, Skeletal pathology, Neurologic Examination, Paper, Reproducibility of Results, Sensitivity and Specificity, Toes pathology, Toes physiology, Foot pathology, Foot physiology, Leprosy physiopathology, Muscle Weakness diagnosis, Muscle, Skeletal physiopathology, Paralysis diagnosis
- Abstract
Plantar intrinsic foot muscles provide structure to the foot during walking and thus regulate mechanical foot sole stresses. When paralyzed, for instance in leprosy patients with neuropathy of the distal part of the tibial nerve, there is a high prevalence of plantar ulceration and deformities, especially when muscle weakness goes together with loss of foot sole sensibility. These patients should get immediate care involving education, special footwear and reconstructive surgery before further foot impairment and deformity becomes manifest. Thus far, in leprosy patients little attention is paid to screening of plantar intrinsic muscles activity. This can be done with a new simple and non-invasive method, the Paper Grip Test (PGT). There are two variants for detecting intrinsic muscle weakness of the foot, PGT1 for the great toe and PGT2 for the combined lesser toes. In this study, 517 leprosy patients and 170 healthy volunteers were investigated with the PGT. Sensibility of the foot sole was tested by means of a 10 gram monofilament. Specificity to the PGT1 is found to be about 95.3% which is considered good for physical diagnostic tests. PGT2 is less specific than PGT1. Individual muscle power and understanding of the patient seems to influence the outcome of the test to a certain extent. Sensitivity can only be calculated when the diagnosis is confirmed by electromyography. Especially patients with anesthetic feet, females, older patients and patients with PN-, BB- or LL-types of leprosy appeared to have a higher prevalence of intrinsic foot muscle weakness. All results were analyzed by means of the bivariate Pearson correlation-analysis and proved to be statistically significant (p = < 0.05). It is concluded that the PGT1, more than the PGT2, is a useful screening test on the function of plantar intrinsic foot muscles in leprosy patients in hospitals and during fieldwork in developing countries.
- Published
- 2002
3. A new approach in muscle training to rehabilitate the hand in leprosy.
- Author
-
Sharangpani RC, Kulkarni VN, and Mehta JM
- Subjects
- Adult, Hand physiopathology, Hand surgery, Hand Deformities, Acquired physiopathology, Humans, Leprosy physiopathology, Male, Movement, Paper, Hand Deformities, Acquired rehabilitation, Leprosy rehabilitation, Physical Therapy Modalities
- Abstract
Rehabilitation of the hand in Leprosy with its deformities and anaesthesia no doubt poses a formidable challenge as far as rehabilitation is concerned. Here we have applied a combination of latest concepts in sports physiology and the exercise followed by the students of ancient Indian martial art known as Krishni Vidya. This exercise consists of crumpling a newspaper sheet with a single hand without any external support. We are unable to explain the type of exercise done by the people before existence of newspaper. They might be using naturally occurring materials for the same like woodbark. With this exercise we have been able to improve the function of the hand remarkably well and the rehabilitation time following surgery is drastically reduced, with function returning close to normalcy. The full function is achieved within four weeks from the date of removal of plaster as compared to eight to ten weeks or more with conventional physical therapy. This full function is not only in mobility but also in co-ordination, static and dynamic strength, speed of movement and flexibility required of a normal hand. 16 patients operated for lumbrical replacement (using sublimis as a motor from the long finger) at the Dr. Bandorawalla Leprosy Hospital were put under the paper crumpling exercise. It was observed that the average time for the achievement of fully close fist was two weeks. (All of them had thumb function intact, i.e. either normal or operated-out of sixteen, four patients were operated for opponens prior to lumbrical replacement).
- Published
- 1985
4. Use of Whatman chromatography paper for serological studies in leprosy in the field.
- Author
-
Bhatia VN, Sudarsanam D, and Roy RG
- Subjects
- Antibodies, Bacterial analysis, Blood Specimen Collection methods, Fluorescent Antibody Technique, Humans, Mycobacterium bovis, Paper, Blood Specimen Collection instrumentation, Leprosy immunology
- Abstract
Recently W.H.O. recommended further serological studies on leprosy using samples collected on filter paper strips. A study was therefore taken up at C.L.T. and R.I., Chengalpattu, to find out the relative efficiency of the serological tests conducted on sera and filter paper eluates. FLA-ABS and FA-BCG tests were carried out on 100 paired samples. With the former, exactly the same titres were obtained in 42% and with the latter in 52% cases. Most of the others showed positivity at one-dilution-low titres. In 6-8% cases only, the filter paper technique showed negativity. The correlation co-efficient was +0.87 with FLA-ABS and +0.85 with FA-BCG test. The filter paper technique was operationally more convenient and was acceptable without substantially loosing the efficacy.
- Published
- 1985
5. Sensory testing with the sharp point of a folded piece of paper
- Author
-
Hui Mei Cheng and Sujith Prasad Kumarasinghe
- Subjects
Hypesthesia ,Paper ,business.industry ,Sharp point ,Leprosy ,MEDLINE ,Medicine ,Humans ,Computer vision ,Artificial intelligence ,Dermatology ,business ,Sensory analysis - Published
- 2015
6. The paper grip test for screening on intrinsic muscle paralysis in the foot of leprosy patients
- Author
-
Maartje M L, de Win, Wim J, Theuvenet, Paul W, Roche, Rob A, de Bie, and Henk, van Mameren
- Subjects
Adult ,Male ,Neurologic Examination ,Paper ,Muscle Weakness ,Foot ,Foot Deformities, Acquired ,Reproducibility of Results ,Middle Aged ,Toes ,Sensitivity and Specificity ,Leprosy ,Humans ,Mass Screening ,Paralysis ,Female ,Muscle, Skeletal ,Aged - Abstract
Plantar intrinsic foot muscles provide structure to the foot during walking and thus regulate mechanical foot sole stresses. When paralyzed, for instance in leprosy patients with neuropathy of the distal part of the tibial nerve, there is a high prevalence of plantar ulceration and deformities, especially when muscle weakness goes together with loss of foot sole sensibility. These patients should get immediate care involving education, special footwear and reconstructive surgery before further foot impairment and deformity becomes manifest. Thus far, in leprosy patients little attention is paid to screening of plantar intrinsic muscles activity. This can be done with a new simple and non-invasive method, the Paper Grip Test (PGT). There are two variants for detecting intrinsic muscle weakness of the foot, PGT1 for the great toe and PGT2 for the combined lesser toes. In this study, 517 leprosy patients and 170 healthy volunteers were investigated with the PGT. Sensibility of the foot sole was tested by means of a 10 gram monofilament. Specificity to the PGT1 is found to be about 95.3% which is considered good for physical diagnostic tests. PGT2 is less specific than PGT1. Individual muscle power and understanding of the patient seems to influence the outcome of the test to a certain extent. Sensitivity can only be calculated when the diagnosis is confirmed by electromyography. Especially patients with anesthetic feet, females, older patients and patients with PN-, BB- or LL-types of leprosy appeared to have a higher prevalence of intrinsic foot muscle weakness. All results were analyzed by means of the bivariate Pearson correlation-analysis and proved to be statistically significant (p =0.05). It is concluded that the PGT1, more than the PGT2, is a useful screening test on the function of plantar intrinsic foot muscles in leprosy patients in hospitals and during fieldwork in developing countries.
- Published
- 2002
7. Evaluation of gelatin particle agglutination assay for the detection of anti-PGLI antibodies. Comparison with ELISA method and applicability on a large scale study using blood collected on filter paper
- Author
-
Suzanne Chanteau, J. L. Cartel, J.-F. Roux, and Jean-Paul Boutin
- Subjects
Paper ,musculoskeletal diseases ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,food.ingredient ,Enzyme-Linked Immunosorbent Assay ,Sensitivity and Specificity ,Gelatin ,Gastroenterology ,Serology ,food ,Particle agglutination ,Agglutination Tests ,Leprosy ,Internal medicine ,Direct agglutination test ,Humans ,Medicine ,Elisa method ,Antigens, Bacterial ,Blood Specimen Collection ,Filter paper ,biology ,business.industry ,General Medicine ,Antibodies, Bacterial ,Mycobacterium leprae ,Titer ,Immunology ,biology.protein ,Glycolipids ,Antibody ,business - Abstract
Given the technical difficulties of the ELISA method, a gelatin particle agglutination test (MLPA) has been developed recently for the detection of anti-PGLI antibodies. The purpose of this study was to compare these 2 tests. MLPA was found to be less specific than ELISA (91% versus 98%, chi 2 = 66.8, p less than 0.001). The sensitivity of both tests was of 95% for the diagnosis of multibacillary patients. In the case of paucibacillary patients. MLPA was found to be less sensitive than ELISA (21% versus 35%, chi 2 = 6.98, p greater than 0.01). The agreement between the 2 tests for a positive or a negative result was satisfying (85% to 100%), except for the weakly seropositive individuals (71%). The correlation between OD obtained with ELISA and antibody titre obtained with MLPA was statistically significant (r = 0.70, p less than 0.001). Conversely to ELISA, MLPA was not applicable on blood samples absorbed on filter paper without a serious loss of sensitivity. In conclusion, this study demonstrated that the MLPA test can only reliably detect anti-PGLI antibodies in multibacillary cases.
- Published
- 1991
8. A new approach in muscle training to rehabilitate the hand in leprosy
- Author
-
R C, Sharangpani, V N, Kulkarni, and J M, Mehta
- Subjects
Adult ,Male ,Paper ,Leprosy ,Movement ,Hand Deformities, Acquired ,Humans ,Hand ,Physical Therapy Modalities - Abstract
Rehabilitation of the hand in Leprosy with its deformities and anaesthesia no doubt poses a formidable challenge as far as rehabilitation is concerned. Here we have applied a combination of latest concepts in sports physiology and the exercise followed by the students of ancient Indian martial art known as Krishni Vidya. This exercise consists of crumpling a newspaper sheet with a single hand without any external support. We are unable to explain the type of exercise done by the people before existence of newspaper. They might be using naturally occurring materials for the same like woodbark. With this exercise we have been able to improve the function of the hand remarkably well and the rehabilitation time following surgery is drastically reduced, with function returning close to normalcy. The full function is achieved within four weeks from the date of removal of plaster as compared to eight to ten weeks or more with conventional physical therapy. This full function is not only in mobility but also in co-ordination, static and dynamic strength, speed of movement and flexibility required of a normal hand. 16 patients operated for lumbrical replacement (using sublimis as a motor from the long finger) at the Dr. Bandorawalla Leprosy Hospital were put under the paper crumpling exercise. It was observed that the average time for the achievement of fully close fist was two weeks. (All of them had thumb function intact, i.e. either normal or operated-out of sixteen, four patients were operated for opponens prior to lumbrical replacement).
- Published
- 1985
9. Use of Whatman chromatography paper for serological studies in leprosy in the field
- Author
-
V N, Bhatia, D, Sudarsanam, and R G, Roy
- Subjects
Paper ,Blood Specimen Collection ,Leprosy ,Fluorescent Antibody Technique ,Humans ,Antibodies, Bacterial ,Mycobacterium bovis - Abstract
Recently W.H.O. recommended further serological studies on leprosy using samples collected on filter paper strips. A study was therefore taken up at C.L.T. and R.I., Chengalpattu, to find out the relative efficiency of the serological tests conducted on sera and filter paper eluates. FLA-ABS and FA-BCG tests were carried out on 100 paired samples. With the former, exactly the same titres were obtained in 42% and with the latter in 52% cases. Most of the others showed positivity at one-dilution-low titres. In 6-8% cases only, the filter paper technique showed negativity. The correlation co-efficient was +0.87 with FLA-ABS and +0.85 with FA-BCG test. The filter paper technique was operationally more convenient and was acceptable without substantially loosing the efficacy.
- Published
- 1985
10. The Year of the Voucher
- Published
- 1981
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