1. Time to Initiation of Antihypertensive Therapy After Onset of Elevated Blood Pressure in Patients With Primary Proteinuric Kidney Disease
- Author
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Richard Eikstadt, Debbie S. Gipson, Samara Attalla, Meg M. Modes, Susan F. Massengill, Elaine S. Kamil, Patrick E. Gipson, David T. Selewski, Anne Pesenson, Richard A. Lafayette, Donald J. Weaver, Anne Waldo, Matthew Elliott, Jonathan P. Troost, Gia Oh, and Sharon G. Adler
- Subjects
Kidney ,medicine.medical_specialty ,Percentile ,Proteinuria ,hypertension ,business.industry ,Retrospective cohort study ,elevated blood pressure ,lcsh:Diseases of the genitourinary system. Urology ,lcsh:RC870-923 ,medicine.disease ,Blockade ,medicine.anatomical_structure ,Blood pressure ,Nephrology ,Internal medicine ,Chronic kidney disease ,Internal Medicine ,medicine ,medicine.symptom ,Disease management (health) ,proteinuria ,business ,Kidney disease ,Original Research - Abstract
Rationale & Objective: The objective of the study was to estimate the prevalence of hypertension in patients with proteinuric kidney disease and evaluate blood pressure (BP) control. Study Design: Retrospective cohort study. Setting & Participants: Data from adults and children with proteinuric kidney disease enrolled in the multicenter Kidney Research Network Registry were used for this study. Exposure: Proteinuric kidney disease. Outcomes: Hypertension and BP control. Analytical Approach: Patients with white-coat hypertension were excluded. Patients were censored at end-stage kidney disease onset. Patients were defined as hypertensive either by hypertension diagnosis code, having 2 or more encounters with elevated BPs, or treatment with antihypertensive therapy excluding renin-angiotensin-aldosterone system blockade. Elevated BP was defined as greater than 95th percentile for children and >140/90 mm Hg in adults. Sustained BP control was defined as 2 or more consecutive encounters with BPs lower than 95th percentile for children and
- Published
- 2020