1. Hypopharyngeal cancer associated with synchronous oesophageal cancer: risk factors and benefits of image-enhanced endoscopic screening.
- Author
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Ni XG, Zhang QQ, Zhu JQ, and Wang GQ
- Subjects
- Adult, Aged, Aged, 80 and over, Female, Humans, Image Enhancement methods, Male, Middle Aged, Narrow Band Imaging methods, Retrospective Studies, Risk Factors, Carcinoma diagnostic imaging, Esophageal Neoplasms diagnostic imaging, Esophagoscopy methods, Hypopharyngeal Neoplasms diagnostic imaging, Laryngoscopy methods, Neoplasms, Multiple Primary diagnostic imaging
- Abstract
Objectives: To explore the risk factors associated with the occurrence of synchronous oesophageal cancer in patients with hypopharyngeal cancer, and to investigate the roles of image-enhanced endoscopic screening in the prediction and diagnosis of early oesophageal cancer., Methods: The clinical characteristics of patients with hypopharyngeal cancer (n = 160) were analysed. All patients underwent laryngoscopic and gastroscopic examination using image-enhanced endoscopic techniques before treatment., Results: Of 160 hypopharyngeal cancer patients, 43 (27 per cent) had synchronous oesophageal cancer. Heavy drinking (odds ratio = 4.787, p = 0.029) and local invasion of three or more anatomical sites (odds ratio = 14.391, p = 0.000) were independent risk factors for synchronous oesophageal cancer. Narrow-band imaging laryngoscopy could detect more invaded anatomical sites than ordinary white light endoscopy (t = 8.532, p = 0.000). More early oesophageal cancer cases were detected with Lugol chromoendoscopy than with non-Lugol iodine staining examination (χ2 = 4.925, p = 0.026)., Conclusion: Synchronous oesophageal cancer is common in patients with hypopharyngeal cancer. The heavy drinking patients with hypopharyngeal cancer should undergo intensive monitoring. Image-enhanced endoscopic screening is helpful in the prediction and early detection of second primary oesophageal cancer.
- Published
- 2018
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