1. Strigolactones, from Plants to Human Health: Achievements and Challenges.
- Author
-
Dell'Oste V, Spyrakis F, and Prandi C
- Subjects
- Adaptation, Physiological, Agriculture methods, Agrochemicals isolation & purification, Agrochemicals metabolism, Agrochemicals pharmacology, Anti-Bacterial Agents biosynthesis, Anti-Bacterial Agents isolation & purification, Anti-Bacterial Agents pharmacology, Antineoplastic Agents isolation & purification, Antineoplastic Agents metabolism, Apoptosis drug effects, Heterocyclic Compounds, 3-Ring isolation & purification, Heterocyclic Compounds, 3-Ring metabolism, Humans, Inflammation prevention & control, Lactones isolation & purification, Lactones metabolism, Mycorrhizae chemistry, Neoplasms drug therapy, Patents as Topic, Plant Growth Regulators biosynthesis, Plant Growth Regulators isolation & purification, Plants chemistry, Sesquiterpenes isolation & purification, Sesquiterpenes metabolism, Stress, Physiological, Weed Control methods, Antineoplastic Agents pharmacology, Heterocyclic Compounds, 3-Ring pharmacology, Lactones pharmacology, Mycorrhizae metabolism, Plant Growth Regulators pharmacology, Plants metabolism, Sesquiterpenes pharmacology
- Abstract
Strigolactones (SLs) are a class of sesquiterpenoid plant hormones that play a role in the response of plants to various biotic and abiotic stresses. When released into the rhizosphere, they are perceived by both beneficial symbiotic mycorrhizal fungi and parasitic plants. Due to their multiple roles, SLs are potentially interesting agricultural targets. Indeed, the use of SLs as agrochemicals can favor sustainable agriculture via multiple mechanisms, including shaping root architecture, promoting ideal branching, stimulating nutrient assimilation, controlling parasitic weeds, mitigating drought and enhancing mycorrhization. Moreover, over the last few years, a number of studies have shed light onto the effects exerted by SLs on human cells and on their possible applications in medicine. For example, SLs have been demonstrated to play a key role in the control of pathways related to apoptosis and inflammation. The elucidation of the molecular mechanisms behind their action has inspired further investigations into their effects on human cells and their possible uses as anti-cancer and antimicrobial agents.
- Published
- 2021
- Full Text
- View/download PDF