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During lower-extremity rehabilitation training, muscle activity status needs to be monitored in real time to adjust the assisted force appropriately, but it is a challenging task to obtain muscle force noninvasively. Mechanomyography (MMG) signals offer unparalleled advantages over sEMG, reflecting the intention of human movement while being noninvasive. Therefore, in this paper, based on MMG, a combined scheme of gray relational analysis (GRA) and support vector regression optimized by an improved cuckoo search algorithm (ICS-SVR) is proposed to estimate the knee joint extension force. Firstly, the features reflecting muscle activity comprehensively, such as time-domain features, frequency-domain features, time-frequency-domain features, and nonlinear dynamics features, were extracted from MMG signals, and the relational degree was calculated using the GRA method to obtain the correlation features with high relatedness to the knee joint extension force sequence. Then, a combination of correlated features with high relational degree was input into the designed ICS-SVR model for muscle force estimation. The experimental results show that the evaluation indices of the knee joint extension force estimation obtained by the combined scheme of GRA and ICS-SVR were superior to other regression models and could estimate the muscle force with higher estimation accuracy. It is further demonstrated that the proposed scheme can meet the need of muscle force estimation required for rehabilitation devices, powered prostheses, etc.

Mechanomyography (MMG) is an important muscle physiological activity signal that can reflect the amount of motor units recruited as well as the contraction frequency. As a result, MMG can be utilized to estimate the force produced by skeletal muscle. However, cross-talk and time-series correlation severely affect MMG signal recognition in the real world. These restrict the accuracy of dynamic muscle force estimation and their interaction ability in wearable devices. To address these issues, a hypothesis that the accuracy of knee dynamic extension force estimation can be improved by using MMG signals from a single muscle with less cross-talk is first proposed. The hypothesis is then confirmed using the estimation results from different muscle signal feature combinations. Finally, a novel model (improved grey wolf optimizer optimized long short-term memory networks, i.e., IGWO-LSTM) is proposed for further improving the performance of knee dynamic extension force estimation. The experimental results demonstrate that MMG signals from a single muscle with less cross-talk have a superior ability to estimate dynamic knee extension force. In addition, the proposed IGWO-LSTM provides the best performance metrics in comparison to other state-of-the-art models. Our research is expected to not only improve the understanding of the mechanisms of quadriceps contraction but also enhance the flexibility and interaction capabilities of future rehabilitation and assistive devices. [ABSTRACT FROM AUTHOR]