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Your search keyword '"Notaro, G."' showing total 5 results
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5 results on '"Notaro, G."'

1. 3-BETA,5-ALPHA,6-BETA-TRIHYDROXYLATED STEROLS WITH A SATURATED NUCLEUS FROM 2 POPULATIONS OF THE MARINE SPONGE CLIONA-COPIOSA

Author

NOTARO G., SICA D., Corriero G., PICCIALLI, VINCENZO, Notaro, G., Piccialli, Vincenzo, Sica, D., and Corriero, G.

Subjects
sponge, trihydroxisterol, Cliona copiosa, Isolation
Abstract

Two different populations of the marine sponges Cliona copiosa, collected in two different sites of the Mediterranean sea, were examined for polyoxygenated sterols. C. copiosa from the bay of Naples contained 5-alpha-cholestane-3-beta,5, 6-beta-triol [1] and the new trihydroxysterols (22E)-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [2], (22E,24S)-24-methyl-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [3], (22E,24R)-24-methyl-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [4], (24R)-24-ethyl-5-alpha-cholestane-3-beta,5,6-beta-triol [5], and (24S)-24-ethyl-5-alpha-cholestane-3-beta,5,6-beta-triol [6]. The population collected from Marsala lagoon, Sicily, contained only sterols 1, 5, and 6. The structures of these compounds were deduced by analysis of spectral data. Partial synthesis of compounds 1, 5, and 6 confirmed the structure assignment

Published
1991

2. New Steroidal Hydroxyketones and Closely Related Diols from the Marine Sponge Cliona copiosa

Author

Vincenzo Piccialli, Giacomo Notaro, Donato Sica, Notaro, G., Piccialli, Vincenzo, and Sica, D.

Subjects
Pharmacology, Stereochemistry, Organic Chemistry, steroidal hydroxyketone, Pharmaceutical Science, Cliona copiosa, Biology, biology.organism_classification, Animal origin, Chemical correlation, Analytical Chemistry, sponge, Sponge, Complementary and alternative medicine, Drug Discovery, Molecular Medicine, isolation
Abstract

DELTA5-3beta-Hydroxy-7-ketosteroids 1-7, DELTA5-3beta,7beta-dihydroxysterols 8-13, and DELTA5-3beta,7alpha-dihydroxysterols 14-17 were isolated from the sponge Cliona copiosa, and the structures were elucidated by spectroscopic methods and chemical correlation with known compounds.

Published
1992
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3. New Tetrahydroxylated Sterols from the Marine Sponge Spongia officinalis

Author

Anna Migliuolo, Giacomo Notaro, Donato Sica, Vincenzo Piccialli, Migliuolo, A., Notaro, G., Piccialli, Vincenzo, and Sica, D.

Subjects
Pharmacology, Spongia officinalis, biology, Ecology, Tetrahydroxylated sterol, Organic Chemistry, Pharmaceutical Science, Isolation (microbiology), biology.organism_classification, Animal origin, Sterol, Isolation, Analytical Chemistry, sponge, Sponge, Complementary and alternative medicine, Drug Discovery, Botany, Molecular Medicine
Abstract

Six new tetrahydroxylated sterols 1-6 were isolated from the marine sponge Spongia officinalis. The structures of these compounds, including stereochemical details, were deduced by H-1 and C-13 nmr, H-1- H-1 COSY, and nOe difference spectroscopy

Published
1990
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4. Minor 5,6-Secosterols from the Marine Sponge Hippospongia communis. Isolation and Synthesis of (7Z,22E,24R)-24-Methyl-5,6-secocholesta-7,22-diene-3β,5β,6-triol

Author

Vincenzo Piccialli, Donato Sica, Anna Madaio, Giacomo Notaro, M. A. D. A. I. O., A., Notaro, G., Piccialli, Vincenzo, and Sica, D.

Subjects
Pharmacology, Diene, biology, Stereochemistry, Hippospongia communis, medicine.medical_treatment, Organic Chemistry, Pharmaceutical Science, biology.organism_classification, Isolation (microbiology), Isolation, Analytical Chemistry, Steroid, sponge, chemistry.chemical_compound, Sponge, Complementary and alternative medicine, chemistry, Drug Discovery, medicine, Molecular Medicine, Triol, minor 5 6 secosterol
Abstract

Eight new 5,6-secosterols were isolated from the sponge H. communis and their structures elucidated by anal. of spectral data. A partial synthesis of (7Z,22E,24R)-24-methyl-5,6-secocholesta-7,22-diene-3β,5β,6-triol (I) confirmed the structure assignment

Published
1990
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5. A FURTHER C15 NONTERPENOID POLYBROMOETHER FROM THE ENCRUSTING SPONGE MYCALE-ROTALIS

Author

Federico Giordano, Luciano Mayol, Vincenzo Piccialli, Giacomo Notaro, Donato Sica, Notaro, G., Piccialli, Vincenzo, Sica, D., Mayol, Luciano, and Giordano, F.

Subjects
Pharmacology, biology, Ecology, Stereochemistry, Organic Chemistry, Pharmaceutical Science, Mycale rotalis, biology.organism_classification, polybrominated C15 acetogenin, Animal origin, Analytical Chemistry, Sponge, chemistry.chemical_compound, Complementary and alternative medicine, chemistry, Drug Discovery, Acetogenin, Molecular Medicine, isolation, encrusting sponge
Abstract

A new cyclic polybrominated C 15 acetogenin 1 has been isolated from the encrusring sponge Mycale rotalis, and its structure has been determined through a combination of spectroscopic and single crystal X-ray diffraction analyses and simple chemical transformations

Published
1992

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