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Background: Post-infectious irritable bowel syndrome (PI-IBS) has been defined as a new onset of IBS following an episode of acute infectious diarrhea. Objective: To determine the frequency of postinfectious irritable bowel syndrome (PI-IBS) among children who have an episode of acute infectious diarrhea. Subjects and Methods: A case control longitudinal study was conducted on 93 children who fulfilled the criteria for diagnosis of acute infectious gastroenteritis. Patients were recruited from the Outpatient Clinic, Children's Hospital, Ain Shams University, during a period of 6 months and were followed up for 3 months for the development of symptoms of IBS according to Rome IV criteria for diagnosis of IBS. They were compared to 100 age- and sex-matched controls who do not have history of acute infectious gastroenteritis during the last 3 months before enrollment. Result: The age of studied cases ranged between (4-15) years old with a mean ±SD=9.26 ± 3.20 years. Females represented 61.3% of cases. PI-IBS occurred in 14%of cases with age ranged between (4-14) years old and females represented 61.5% of PI-IBS cases. Meanwhile, the incidence of IBS 3.2% of uninfected controls (relative risk, RR = 4.33). Most cases of PI-IBS were diarrhea prominent. There was no significant association with the causative organism identified among cases. Rota virus represented the most common organism among our patients with incidence of (32.3%) followed by campylobacter, salmonella, adeno virus, and giardia with incidence of (9.7%), (8.6%), (5.4%), (6.5%), respectively, while (37.6%) of patients have negative stool cultures for the mentioned organisms. Conclusion: The frequency of PI-IBS is common among pediatrics but does not seem to be associated with the causative organism of the preceding episode of infectious diarrhea. Raising the awareness about this entity is of outmost importance as this will allow targeted treatment. [ABSTRACT FROM AUTHOR]

Abstract: Gastrointestinal infection is ubiquitous worldwide though the pattern of infection varies widely. Poor hygiene and lack of piped water is associated with a high incidence of childhood infection, both viral and bacterial. However in developed countries bacterial infection is commoner in young adults. Studies of bacterial infections in developed countries suggest 75% of adults fully recover, however around 25% have long lasting changes in bowel habit and a smaller number develop the irritable bowel syndrome (IBS). Whether the incidence is similar in developing countries is unknown. Post-infective IBS (PI-IBS) shares many features with unselected IBS but by having a defined onset allows better definition of risk factors. These are in order of importance: severity of initial illness, smoking, female gender and adverse psychological factors. Symptoms may last many years for reasons which are unclear. They are likely to include genetic factors controlling the immune response, alterations in serotonin signaling, low grade mucosal inflammation maintained by psychological stressors and alterations in gut microbiota. As yet there are no proven specific treatments, though 5HT3 receptor antagonists, anti-inflammatory agents and probiotics are all logical treatments which should be examined in large well-designed randomised placebo controlled trials. [Copyright &y& Elsevier]

Irritable bowel syndrome (IBS) is a widespread functional bowel disorder and its prevalence in Western societies ranges from 3-20%. The present study aimed to determine the prevalence of IBS in eastern Turkey, particularly in urban parts of Elazig where 250 000 people live. Of the 18 primary care centers, four were randomly selected for this study. All individuals (aged >17 years) living around the service area of these health centers were included. A total of 1900 subjects were randomly selected using the personal health records from the primary care centers. The total number of subjects that could be contacted was 1766. A questionnaire with multiple choice questions was applied to the subjects by medical students using the face-to-face technique. Prevalence of IBS and distribution of symptoms were evaluated by the Rome II criteria. Of the 1766 subjects, 45.4% were male and 54.6% were female. Prevalence of IBS was 5% in males, 7.4% in females and 6.3% overall. The percentage of subjects with IBS in the 17–30 years age group was 26.2%; 52.3% in the 30–50 years age group and 21.6% in the above 50 years age group. Prevalence of IBS was highest (10.2%) in persons who were illiterate and lowest (3.0%) in university graduates. A positive correlation was determined between low economical status and prevalence of IBS ( P < 0.05). Although IBS is widely present in Turkey, its prevalence is lower than that reported in Western communities. In the region where this study was carried out, IBS was more prevalent in females and in individuals with low educational and economical status. [ABSTRACT FROM AUTHOR]

Objective: The bladder and colon are from the same embryological origin and anatomically neighbors, and share a motor nerve. Since they are parts of the pelvic floor structure, the striated closing and supporting muscles are also the same. The bladder and colon have a similar function for storing and emptying urine and stool, respectively. Based on many similar features of these two diseases and their high prevalence in general population, it was aimed to investigate the frequency of gastroenterological complaints in patients with overactive bladder within this study. Method: This study was carried out with patients who applied Bezmialem Vakıf University Urology Clinic at February-December 2019. The 151 patients, who were diagnosed as overactive bladder according to OAB-V8, were informed about the subject and included in the study regarding their consent. Birmingham irritable bowel syndrome (IBS) symptom questionnaire was used to investigate the existence of IBS and it was aimed to interrogate the frequency of gastroenterological symptoms through this investigation. Results: The mean age of the 151 patients that participated to this study was 48.17±14.97 years. It was also reported that 109 (72.2%) of these participants were women and 42 (27.8%) of them were men. Participants’ average age was evaluated with the average scores of related questions investigating diarrhea, constipation and fecal urgency, respectively; it was seen that there was no relationship between age and related questions that interrogated these three symptoms (p>0.05). Nevertheless, participants’ mean age and the questions interrogating abdominal pain were considered as statistically significant (p<0.05). A statistically significant correlation was found between the participants’ OAB-V8 scores and Birmingham IBS symptom questionnaire scores (p<0.05). Conclusion: Previous studies have implied that patients with OAB have some other complaints besides urinary system complaints. Hereby, it is important to evaluate patients diagnosed with OAB with a multidisciplinary approach. To represent the population better, larger scale and multicenter studies are needed. [ABSTRACT FROM AUTHOR]