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The aim of this experiment was to investigate the effects of Chinese herbal preparations on serum biochemical and immune indexes, intestinal tissue morphology and digestive enzyme activity of Hu sheep. Eighteen 3-month-old healthy Hu male lambs with an average body weight of (19.60± 1.63) kg were randomly divided into 3 groups (control group, group A and group B) with 6 sheep in each group. The sheep in control group were fed a basal diet, and the sheep in groups A and B were fed 0.5% and 1.0% Chinese herbal preparations in concentrate supplement. The experiment lasted for 90 days. The results showed as follows: ① the total protein (TP) of sheep in group A was significantly higher than that of in control group (P<0.05), and the albumin (ALB) of control group was extremely significantly lower than that of groups A and B (P<0.05). ② Immunoglobulin A (IgA) in group B was extremely significantly higher than that of in control group and group A (P<0.01), immunoglobulin M (IgM) in control group was extremely significantly lower than that of groups A and B (P<0.01), lysozyme activity in control group was extremely significantly lower than that of groups A and B (P<0.01). ③ Ileum villi length in group B was extremely significantly higher than that in group A and control group (P<0.01), and muscle thickness in control group was extremely significantly lower than that in groups A and B (P<0.01). The muscle thickness of duodenum group B was significantly higher than that of group A (P<0.05), and the ratio of velvet to crypto in group B was significantly higher than that of control group (P<0.05). The villus length and pile-to-crypto ratio of jejunum in control group were extremely significantly lower than those in groups A and B (P<0.01). The results showed that Chinese herbal preparations could significantly improve the immunity and intestinal absorption and utilization ability of Hu sheep, the effect of 1% addition is better. [ABSTRACT FROM AUTHOR]