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• Different residential groups varied in injection networks and travel behaviors. • Concentrated risk activity spaces of three residential groups spatially overlapped. • Concentrated risk activity spaces related to multiple neighborhood disadvantages. • Identified risk activity spaces useful for understanding syndemics in PWID populations. Recent studies underscore the significance of adopting a syndemics approach to study opioid misuse, overdose, hepatitis C (HCV) and HIV infections, within the broader context of social and environmental contexts in already marginalized communities. Social interactions and spatial contexts are crucial structural factors that remain relatively underexplored. This study examines the intersections of social interactions and spatial contexts around injection drug use. More specifically, we investigate the experiences of different residential groups among young (aged 18-30) people who inject drugs (PWID) regarding their social interactions, travel behaviors, and locations connected to their risk behaviors. By doing so, we aim to achieve a more comprehensive understanding of the multidimensional risk environment, thereby facilitating the development of informed policies. We collected and examined data regarding young PWID's egocentric injection network and geographic activity spaces (i.e., where they reside, inject drugs, purchase drugs, and meet sex partners). Participants were stratified based on the location of all place(s) of residence in the past year i.e., urban, suburban, and transient (both urban and suburban) to i) elucidate geospatial concentration of risk activities within multidimensional risk environments based on kernel density estimates; and ii) examine spatialized social networks for each residential group. Participants were mostly non-Hispanic white (59%); 42% were urban residents, 28% suburban, and 30% transient. We identified a spatial area with concentrated risky activities for each residential group on the West side of Chicago in Illinois where a large outdoor drug market area is located. The urban group (80%) reported a smaller concentrated area (14 census tracts) compared to the transient (93%) and suburban (91%) with 30 and 51 tracts, respectively. Compared to other areas in Chicago, the identified area had significantly higher neighborhood disadvantages. Significant differences were observed in social network structures and travel behaviors: suburban participants had the most homogenous network in terms of age and residence, transient participants had the largest network (degree) and more non-redundant connections, while the urban group had the shortest travel distance for all types of risk activities. Distinct residential groups exhibit varying patterns of network interaction, travel behaviors, and geographical contexts related to their risk behaviors. Nonetheless, these groups share common concentrated risk activity spaces in a large outdoor urban drug market area, underscoring the significance of accounting for risk spaces and social networks in addressing syndemics within PWID populations. [ABSTRACT FROM AUTHOR]

Despite growing awareness of opioid use disorder (OUD), fatal overdoses and downstream health conditions (e.g., hepatitis C and HIV) continue to rise in some populations. Various interrelated structural forces, together with social and economic determinants, contribute to this ongoing crisis; among these, access to medications for opioid use disorder (MOUD) and stigma towards people with OUD remain understudied. We combined data on methadone, buprenorphine, and naltrexone providers from SAMHSA's 2019 directory, additional naltrexone providers from Vivitrol's location finder service, with a nationally representative survey called "The AmeriSpeak survey on stigma toward people with OUD." Integrating the social-ecological framework, we focus on individual characteristics, personal and family members' experience with OUD, and spatial access to MOUD at the community level. We use nationally representative survey data from 3008 respondents who completed their survey in 2020. Recognizing that stigma is a multifaceted construct, we also examine how the process varies for different types of stigma, specifically perceived dangerousness and untrustworthiness, as well as social distancing measures under different scenarios. We found a significant association between stigma and spatial access to MOUD — more resources are related to weaker stigma. Respondents had a stronger stigma towards people experiencing current OUD (versus past OUD), and they were more concerned about OUD if the person would marry into their family (versus being their coworkers). Additionally, respondents' age, sex, education, and personal experience with OUD were also associated with their stigma, and the association can vary depending on the specific type of stigma. Overall, stigma towards people with OUD was associated with both personal experiences and environmental measures. • Stigma towards opioid use is multi-dimensional and relies on context. • Both personal experience and community measures were associated with stigma. • More providers of medications in the neighborhood associated with weaker stigma. • Education and family's opioid use experience related to varied stigma differently. • Younger respondents with personal history of opioid use showed weaker stigma. [ABSTRACT FROM AUTHOR]

Despite their positive effects in promoting participatory politics, digital publics have also manifested an offensive vernacular culture. This study takes a social network analytic approach to explain the contagion of offensive speech in online discussion contexts. The study examines four social interactional mechanisms underlying a user's adoption of political swearing: generalized reciprocity, direct reciprocity, leader-mimicry, and peer-mimicry. The empirical context of this study is a highly popular online discussion forum in Hong Kong. The study examines the effects of social interactional mechanisms on the occurrences of political swearing by analyzing five years of user comments. Findings show that peer-mimicry contributes to the contagion process the most, followed by generalized reciprocity and direct mimicry. The study demonstrates how individual-level speech behaviors spiral into a collective norm that potentially hinders a healthy discussion culture in mediated social spaces. • This study explained the contagion of offensive speech in online discussion. • We analyzed large-scale datasets collected from a popular discussion forum. • Various social interactional mechanisms (e.g., reciprocity and mimicry) were examined. • We illustrated how individual-level offensive speech spirals into a toxic vernacular culture online. [ABSTRACT FROM AUTHOR]