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Through the use of experimental data and Monte Carlo simulations we investigate the shielding properties of spacecraft-shell compositions exposed to 1 GeV/nucleon ^56Fe ions, representative of the worst part of the Galactic Cosmic Ray (GCR) spectrum. Through the use of the Geant4 Radiation Analysis for Space (GRAS) tool, the dose reduction and the ^56Fe-fragmentation induced by those structures currently used to protect part of the International Space Station (ISS) or designed for future inflatable habitats, are analyzed. The possible effects on spacecraft electronics are discussed. [ABSTRACT FROM PUBLISHER]

Space exploration is demanding longer lasting human missions and water resupply from Earth will become increasingly unrealistic. In a near future, the spacecraft water monitoring systems will require technological advances to promptly identify and counteract contingent events of waterborne microbial contamination, posing health risks to astronauts with lowered immune responsiveness. The search for bio-analytical approaches, alternative to those applied on Earth by cultivation-dependent methods, is pushed by the compelling need to limit waste disposal and avoid microbial regrowth from analytical carryovers. Prospective technologies will be selected only if first validated in a flight-like environment, by following basic principles, advantages, and limitations beyond their current applications on Earth. Starting from the water monitoring activities applied on the International Space Station, we provide a critical overview of the nucleic acid amplification-based approaches (i.e., loop-mediated isothermal amplification, quantitative PCR, and high-throughput sequencing) and early-warning methods for total microbial load assessments (i.e., ATP-metry, flow cytometry), already used at a high readiness level aboard crewed space vehicles. Our findings suggest that the forthcoming space applications of mature technologies will be necessarily bounded by a compromise between analytical performances (e.g., speed to results, identification depth, reproducibility, multiparametricity) and detrimental technical requirements (e.g., reagent usage, waste production, operator skills, crew time). As space exploration progresses toward extended missions to Moon and Mars, miniaturized systems that also minimize crew involvement in their end-to-end operation are likely applicable on the long-term and suitable for the in-flight water and microbiological research. Image 1 • Space exploration is demanding longer lasting human missions with no water resupply. • Water technologies at high readiness level complement microbial monitoring in space. • Miniaturized biomolecular techniques and real-time monitoring systems are reviewed. • A single technological solution cannot meet the requirements of water monitoring. • Compromises between analytical performances and technical issues are critical. [ABSTRACT FROM AUTHOR]