Search

Methods: Twenty nine patients (M/F: 19/10, age 67±9 years) with stable angina, and without prior myocardial infarction underwent cardiac catheterization, during which wall motion analysis (centerline method), quantitative coronary angiography (QCA) and CTFC (using a frame counter on a cine viewer) were measured. All patients had a standard 2-D and Doppler echocardiography and Pulsed wave TDI of systolic (Sm) and diastolic velocities (early: Em, late: Am) from the perfusion territories of the left anterior descendens (LAD), the circumflex (CX) and the right coronary artery (RCA), using the apical views, before and 24 hours after PCI. Results: All patients underwent elective PCI (19 LAD, 4 CX and 6 RCA stenoses, range 61 - 94%). There was TIMI grade 3 flow before and after PCI. Regional wall motion (centerline method and wall motion score with echocardiography) was normal in all patients before and after PCI. Significant improvement in the following parameters was observed post PCI (mean ± SD): QCA, 72±12% to 8± 6%; cTFC, 35 ±19 to 22±8; Sm, 5.4±1.1 to 8±1.4; p < 0.005 for all. An improvement was also seen in diastolic function E/A ratio from 0.87±0.23 to 0.97±0.2. A significant correlation was found between cTFC and stenosis severity pre PCI (r=0.58, p=0.0028), and the improvement in cTFC and the regional Sm values post PCI (r = 0.79, p

International audience; BACKGROUND: Allergic rhinitis (AR) is common and has been shown to impair social life and sleep. Patients with severe symptoms may have more sleep disturbances than those with a mild form of the disease, but this has never been assessed using a validated tool. The objective of our study was to assess, in patients with AR, whether duration and severity of AR are associated with sleep impairment. METHODS: A nationwide controlled cross-sectional epidemiological study was carried out. A representative sample of 260 French ear, nose, and throat and allergy specialists enrolled 591 patients with AR of at least 1 year's duration. Sleep disorders, sleep quality, and AR were assessed using validated tools (Sleep Disorders Questionnaire, Epworth Sleepiness Scale, and Score for Allergic Rhinitis). The severity of AR was assessed using the Allergic Rhinitis and its Impact on Asthma classification. RESULTS: All dimensions of sleep were impaired by AR, particularly by the severe type. Sleep was significantly more impaired in patients with severe AR than in those with the mild type. The duration of AR (intermittent or persistent) had no effect on sleep. CONCLUSION: These data underline the close relationship between AR and sleep and highlight the need for clinicians, particularly general practitioners, to be attentive in this respect.